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All Journal JURNAL INTEGRASI PROSES Jurnal Inovasi Teknik Kimia
Cika Amalia Shabira
Institut Teknologi Sumatera
Chemical Engineering, Chemistry & Bioengineering Other

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SINTESIS ANTI-SARIAWAN HYDROGEL PATCH FILM DARI EKSTRAK KULIT PISANG KEPOK TERHADAP STAPHYLOCOCCUS AUREUS MENGGUNAKAN METODE ULTRASOUND ASSISTED EXTRACTION Yunita Fahni; Safira Anggarini; Ridho Ramadhan Jakop; Agriadi Dwi Nugroho Putro; Cika Amalia Shabira; Azzaima Ayu Ulisya; Desi Riana Saputri; Wika Atro Auriyani; Damayanti Damayanti; Andri Sanjaya; Ibnu Maulana Hidayatullah
JURNAL INTEGRASI PROSES Vol 13, No 2 (2024)
Publisher : JURNAL INTEGRASI PROSES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/jip.v13i2.27862

Abstract

Penelitian ini mengeksplorasi potensi antibakteri dari ekstrak kulit pisang kepok (Musa spp.) terhadap bakteri Staphylococcus aureus (Sp. aureus) menggunakan metode ultrasound assisted extraction (UAE) dan mengaplikasikannya dalam bentuk patch hydrogel untuk pengobatan sariawan. Ekstrak kulit pisang kepok, yang mengandung senyawa aktif seperti flavonoid, tanin, saponin, dan fitosterol, menunjukkan aktivitas antibakteri yang signifikan terhadap Sp. aureus. Penelitian ini menemukan bahwa waktu sonikasi 50 menit mampu menghasilkan rendemen tertinggi pada ekstraksi kulit pisang kepok. Ekstrak kulit pisang kepok bekerja efektif sebagai antibakteri terhadap Sp. aureus pada konsentrasi 60-80%. Analisis GC-MS mengidentifikasi senyawa antimikroba dan antiinflamasi dalam ekstrak. Formulasi hydrogel patch film dengan ekstrak 60-80% memenuhi standar fisik dan kimia, termasuk ketahanan lipatan dan pH yang sesuai untuk penggunaan di rongga mulut, menunjukkan potensi sebagai bahan anti-sariawan.
OPTIMALISASI PROSES EKSTRAKSI MINYAK KAYU PUTIH MELALUI METODE RE-DISTILASI DALAM SKALA LABORATORIUM DAN PILOT PLANT Rifqi Sufra; Cika Amalia Shabira; Aiman Firjatullah; Misbahudin Alhanif; Yusron Darojat; Desi Riana Saputri; Vina Alfionita; Rizki Sheldian; Tantri Liris Nareswari
Jurnal Inovasi Teknik Kimia Vol. 10 No. 3 (2025): July | INTEKA - Jurnal Inovasi Teknik Kimia
Publisher : Fakultas Teknik Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/inteka.v10i3.14452

Abstract

Cajuput oil is an essential oil of high economic value and is widely used in the pharmaceutical and health industries. However, national production remains suboptimal, partly due to the low 1,8-cineole content. This study aims to compare improvements in cajuput oil quality achieved through laboratory-scale and pilot-scale redistillation processes. Redistillation was applied to cajuput oil obtained from the initial distillation, using young leaves, mature leaves, and mixed leaves as raw materials. The evaluation included organoleptic characteristics, refractive index, and 1,8-cineole content determined by GC–MS analysis. The results indicate that the highest 1,8-cineole content was achieved by redistilling young leaves, reaching 83.84%, and all distillates complied with the quality standards specified in SNI 3954:2014. The re-distillation process was proven to enhance color clarity, aroma, and chemical quality of cajuput oil. Therefore, redistillation shows strong potential for application at the production scale to support the development of high-quality cajuput oil using green technology.
Co-Authors Agriadi Dwi Nugroho Putro Aiman Firjatullah Andri Sanjaya Azzaima Ayu Ulisya Damayanti Damayanti Desi Riana Saputri Ibnu Maulana Hidayatullah Misbahudin Alhanif Ridho Ramadhan Jakop Rifqi Sufra Rizki Sheldian Safira Anggarini Tantri Liris Nareswari Vina Alfionita Wika Atro Auriyani Yunita Fahni Yusron Darojat