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All Journal Jurnal Kimia Riset Jurnal Kreativitas PKM PENITI BANGSA (Pemanfaatan Ilmu Pengetahuan dan Teknologi bagi Masyarakat)
Zulqaida, Salma
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Agriculture, Biological Sciences & Forestry Chemistry Economics, Econometrics & Finance Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Edukasi Pengelolaan Sampah Berbasis Eco enzyme untuk Mengurangi Dampak Pencemaran Lingkungan dan Resiko ISPA di Desa Karangdiyeng Kabupaten Mokokerto Zulqaida, Salma; Indah Budhy, Theresia; Megasari, Ni Luh Ayu; Minan Zuhri, Fu’ad; Qalbani Putri, Ardhanita; Rahmawati, Annisa; Elpira, Ririn; Kristianto, Sonny; Eryna Putri, Rury
PENITI BANGSA (Pemanfaatan Ilmu Pengetahuan dan Teknologi bagi Masyarakat) Vol 2 No 2 (2024): PENITI BANGSA
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/PENITI-BANGSA.v2i22024.421

Abstract

Waste management issues and its environmental and health impacts, particularly Acute Respiratory Infections (ARI), are significant concerns in Desa Karangdiyeng, Kabupaten Mojokerto. A large portion of the community still practices waste burning, which harms both the health and the environment. This community service activity aimed to increase public awareness of environmental pollution risks from waste burning and provide training on creating eco enzymes as an eco-friendly waste management solution. The methods used included seminars on environmental pollution and ARI, as well as practical eco enzyme production training. Results showed a significant improvement in community knowledge, with an average pretest score increasing by 47.5% after attending the seminar and training. Participants were also able to practice making eco enzymes and were given plant seedlings to utilize the eco enzyme as fertilizer. This activity successfully provided benefits by raising awareness of proper waste management and its health impacts, as well as offering practical skills in eco enzyme-based waste management.
Peningkatan Literasi Narkotika dan Psikotropika melalui Edukasi dan Pembentukan Satgas Anti Narkoba di SMPN 1 Pacet Kabupaten Mojokerto Kristianto, Sonny; Yudianto , Ahmad; Putri , Rury Eryna; Widodo , Wimbuh Tri; Ripki, Nadia; Zulqaida, Salma
PENITI BANGSA (Pemanfaatan Ilmu Pengetahuan dan Teknologi bagi Masyarakat) Vol 2 No 2 (2024): PENITI BANGSA
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/PENITI-BANGSA.v2i22024.422

Abstract

Drug abuse among adolescents continues to rise, particularly within school-aged groups. SMPN 1 Pacet in Mojokerto Regency, with students aged 13-15 years old, is an environment vulnerable to this risk. This community service activity aims to increase students' literacy about the dangers of narcotics and psychotropic drugs. This program involved 50 Grade 9 students along with the Osis/MPK and presented experts from Social Service and Airlangga University. Methods included a pre-test, education, practice of urine drug testing using rapid diagnostic tests independently and post-test. The results showed an increase in the average score of students' understanding by 12.4%, as well as the formation of the Anti-Drug Task Force as an agent of change. This success supports the goals of SDG 4 (quality education) and SDG 16 (peace, justice, and strong institutions). This program demonstrates the effectiveness of participatory-based education in creating a drug-free school environment.
BIOACTIVE COMPOUNDS OF Moringa oleifera AS KRASG12C INHIBITORS IN COLORECTAL CANCER: IN SILICO STUDY Marviella, Sephia Tiara; Zulqaida, Salma; Sulisetyawati, Theresia Indah Budhy; Ma'ruf, Anwar
Jurnal Kimia Riset Vol. 9 No. 2 (2024): December
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v9i2.64871

Abstract

KRAS is a GTPase enzyme that regulates cell growth and division. Mutations in KRAS can lead to its permanent activation, resulting in uncontrolled cell growth and cancer progression. Approximately 30–44% of colorectal cancer cases harbor KRAS mutations, with 1–3% involving the KRASG12C variant. Historically considered "undruggable," recent advancements, such as Sotorasib, have demonstrated the potential to target KRASG12C effectively, making it a promising focus for drug discovery. Moringa oleifera, a plant rich in phytochemicals, is a potential source of bioactive compounds with therapeutic applications. In this study, 218 compounds derived from M. oleifera were screened using molecular docking, targeting KRASG12C. Quercetin (3) exhibited the lowest binding affinity (-9.37 kcal/mol) and showed interactions with key residues, including GLN100A, VAL104A, LYS17A, and TYR97A, suggesting a binding mechanism similar to that of Sotorasib as native ligand. The physicochemical analysis further revealed high gastrointestinal absorption, good lipophilicity, and favorable bioavailability scores for Quercetin (3), supporting its potential as a drug candidate. These findings highlight the potential of M. oleifera compounds, particularly quercetin (3), as inhibitors of KRASG12C in colorectal cancer.
Edukasi Optimalisasi Bahan Alam sebagai Ramuan Herbal Kesehatan Reproduksi Remaja di MA Permata Kota Mojokerto Putri, Rury Eryna; Kristianto, Sonny; Yuliani, Gandul Atik; Abid, Istiana Firqah; Afdhila, Zakia; Uktutias, Sendy Ayu Mitra; Zulqaida, Salma; Widodo, Wimbuh Tri
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 4 (2025): Volume 8 No 4 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i4.18733

Abstract

ABSTRAK Bahan alam Indonesia dilaporkan memiliki beragam senyawa aktif seperti alkaloid, flavonoid, dan fenolik, yang menunjukkan aktifitas antibakteri dan antioksidan yang tinggi sehingga dimanfaatkan sebagai ramuan untuk menjaga kesehatan reproduksi. Namun, kurangnya perilaku perawatan diri sejak remaja dapat disebabkan oleh kurangnya kesadaran dan informasi yang memadai tentang cara menjaga kebersihan diri pada masa tersebut. Termasuk rendahnya kesadaran penggunaan bahan alam herbal. Edukasi tentang peningkatan pengetahuan tentang bahan alam sebagai bahan ramuan kesehatan reproduksi kepada siswa di dalam sataun pendidikan menjadi langkah strategis untuk membina siswa memahami problema di atas. Program ini menyasar siswa putri kelas X, Madrasah Aliyah (MA) Permata Kota Mojokerto. Metode pelaksanaannya meliputi tahap persiapan (survey awal), pelaksanaan program edukasi dan demo pembuatan jamu, lalu evaluasi. Berdasarkan hasil evaluasi berupa skor pre- dan post-test, didapatkan peningkatan signifikan performa siswa berupa pengetahuan bahan alam, ramuan yang dapat dibuat dari bahan alam, dan khasiat bahan alam untuk kesehatan reproduksi, yang ditandai dengan pergeseran distribusi skor ke rentang 90-100 atau skor maksimal. Melalui program edukasi di MA Permata Kota Mojokerto ini dapat menumbuhkan kesadaran dan pengetahuan yang baik bahan alam serta pembuatan dan penggunaan ramuan herbal yang tepat untuk menjaga kesehatan reproduksi Kata Kunci: Herbal, Learning Outcomes, Jamu, Student Awareness  ABSTRACT Indonesia's natural resources are reported to contain various active compounds such as alkaloids, flavonoids, and phenolics, which exhibit high antibacterial and antioxidant activities. Those natural resources are valuable as herbal remedies for maintaining reproductive health. However, a lack of self-care practices during adolescence can stem from limited awareness and insufficient information on personal hygiene, including a lack of understanding about the use of herbal natural resources. This program aims to educate students to increase their knowledge about natural resources as ingredients for reproductive health remedies, providing a strategic step to help adolescence address these issues. The program targeted female 10th-grade students of Madrasah Aliyah (MA) Permata, Mojokerto. The implementation included preparatory stages (preliminary surveys), program execution through educational sessions, herbal remedy-making demonstrations, and evaluations. Based on the evaluation, significant improvements were observed in students’ performance, reflected by increased knowledge about natural ingredients, herbal remedies that can be created from them, and their benefits for reproductive health. This was evidenced by a shift in score distribution to the 90-100 range, or the maximum score. This educational program at MA Permata Mojokerto successfully fostered awareness and understanding of natural ingredients, as well as the proper preparation and use of herbal remedies to support reproductive health. Keywords: Herbal Remedies, Learning Outcomes, Jamu, Student Awareness
Co-Authors Abid, Istiana Firqah Afdhila, Zakia Annisa Rahmawati Elpira, Ririn Indah Budhy, Theresia Kristianto, Sonny Ma'ruf, Anwar Marviella, Sephia Tiara Minan Zuhri, Fu’ad Ni Luh Ayu Megasari Qalbani Putri, Ardhanita Ripki, Nadia Rury Eryna Putri Sulisetyawati, Theresia Indah Budhy Uktutias, Sendy Ayu Mitra Wimbuh Tri Widodo Yudianto , Ahmad Yuliani, Gandul Atik