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All Journal Media Kedokteran Hewan Jurnal Kimia Riset Jurnal Medik Veteriner Jurnal Pengabdian Masyarakat Teknik journal of Basic Medical Veterinary Molekul: Jurnal Ilmiah Kimia Andan Jejama: Indonesian Journal Of Community Engagement
Ma'ruf, Anwar
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Engineering Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Veterinary

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Pengabdian kepada Masyarakat Peningkatan Pendapatan Komunitas Serayu Network Banjarnegara Melalui Produksi Kapsul Daun Kelor Ma'ruf, Anwar
Jurnal Pengabdian Masyarakat Teknik Vol 6, No 1 (2023): Jurnal Pengabdian Masyrakat Teknik (JPMT)
Publisher : Fakultas Teknik Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/jpmt.6.1.8-14

Abstract

Tanaman kelor memiliki manfaat selain sebagai tanaman pencegah erosi, daun kelor juga memiliki potensi ekonomi yang tinggi. Masyarakat di DAS Serayu sudah menanam Pohon kelor sebagai pengganti tanaman kentang yang menyebabkan terjadinya erosi tanah. Permasalahan yang dihadapi oleh Komunitas Serayu Network adalah belum adanya pengolahan produk daun kelor, sehingga pemasaran daun kelor belum dapat dilakukan. Kerjasama antara Tim Pelaksana Pengabdian UMP yang terdiri dari lintas disiplin ilmu bekerjasama dengan mitra komunitas Serayu Network melakukan kerjasama produksi kapsul daun kelor.  Dengan adanya kerjasama ini diharapkan dapat meningkatkan kemampuan komunitas Serayu Network dalam produksi kapsul kelor, sehingga permasalahan pasar daun kelor dapat diatasi. Proses pembuatan kapsul daun kelor terdiri dari tahapan : penyortiran kapsul daun kelor, pengeringan daun kelor, pembubukan dan pengayakan daun kelor kering dan pengapsulan daun kelor. Proses pembuatan kapsul daun kelor mudah untuk dilakukan dan mempunyai nilai ekonomi yang cukup tinggi. Penanaman pohon kelor dapat menjadi solusi untuk penggantian tanaman kentang di DAS Serayu, untuk mengurangi laju erosi, dengan pengolahan menjadi kapsul daun kelor. Perlu pendampingan lebih lanjut untuk control kualitas produk kapsul daun kelor dan manajemen pemasaran.
Production of High Protein MOCAF (Modified Cassava Flour) Using Papain and Lactic Acid Bacteria Afifah, DIni Nur; Ma'ruf, Anwar; Putri, Regita Nanda; Santosa, Arif Prashadi; Hamad, Alwani
Molekul Vol 19 No 1 (2024)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2024.19.1.9712

Abstract

Wheat is one of Indonesia's primary sources of carbohydrates. However, the need for wheat still depends on imports. So, developing local flour based on Indonesia's natural resources is necessary. One source of carbohydrates easily found in Indonesia is cassava (Manihot esculenta crantz). Although there are many in Indonesia, the diversification of cassava-based products is still limited. In this research, MOCAF flour was developed and produced by fermenting cassava tubers with lactic acid bacteria. The enzymatic activity during the MOCAF (Modified Cassava Flour) production process is believed to change the physicochemical properties of cassava so that MOCAF products have characteristics similar to wheat flour and are expected to meet the gap between the demand and availability of flour. Even though it can potentially substitute wheat, MOCAF flour only has about 1% protein content, influencing dough rheology. According to the problem, a process modification was done by adding the enzyme papain (PAP) as a support enzyme to improve the performance of lactic acid bacteria (LAB). In order to study the effect of the papain enzyme, variations were made on the ratio of lactic acid starter: papain enzyme (LAB: PAP) and fermentation time. The ratio of (LAB: PAP) was varied to 40:1, 40:3, 40:5, 40:7, and 40:9, while the fermentation period was varied to 24, 48, 72, 96, and 120 hours. The fermentation was conducted by using cassava varieties of Singkur aerobically. The primary starter contained Lactobacillus, sp, developed by PT. Rumah Mocaf Indonesia and the papain enzyme used have an activity of 100,000 U/g. Data analysis showed that the addition of papain enzyme doses with a ratio to the lactic acid starter of 40:7 was able to produce MOCAF with the best characteristics: protein content, starch content, and swelling power of 3.72%, 9.99%, 16.00%, respectively. The data trend of research also showed that the number of papain enzymes only significantly affects starch content and swelling power. On the other hand, fermentation time has a significant effect on these three characteristics (protein, starch, swelling power).
Identifikasi Limbah Pertanian dan Perkebunan Sebagai Bahan Pakan Inkonvensional Di Banyuwangi Agustono, Bodhi; Lamid, Mirni; Ma'ruf, Anwar
Jurnal Medik Veteriner Vol. 1 No. 1 (2017): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (537.369 KB) | DOI: 10.20473/jmv.vol1.iss1.2017.12-22

Abstract

Penelitian ini bertujuan untuk mengumpulkan data bahan pakan inkonvensional dari limbah pertanian dan perkebunan di Kabupaten Banyuwangi. Pakan merupakan aspek terpenting dalam pengelolaan peternakan. Ketersediaan pakan baik di musim hujan maupun musim kemarau harus tetap ada. Penelitian ini menggunakan metode purposive sampling sehingga sampel diambil di Kecamatan Kalibaru, Genteng, Purwoharjo, Songgon, Banyuwangi, Licin, Glagah dan Wongsorejo. Sampel bahan selanjutnya dianalisis proksimat untuk mengetahui kadar serat kasar (SK), protein kasar (PK), lemak kasar (LK), bahan ekstrak tanpa nitrogen (BETN) dan kadar abu. Hasil menunjukkan bahwa limbah jerami padi, jerami kedelai, nanas, rumput gajah, alang-alang, rumput lapang, kaliandra, turi dan lamtoro memiliki dominasi kandungan gizi yang bervariasi. Simpulan penelitian bahwa bahan limbah dapat diformulasikan sebagai pakan ternak inkonvensional.
Efficacy of Sauropus androgynous Leaves Extract Gel on Burn Wound Healing in Albino Rats Panggabean, Rosenna Tiara; Sudjarwo, Sri Agus; Ma'ruf, Anwar; Widiyatno, Thomas Valentinus; Yudaniayanti, Ira Sari; Kurnijasanti, Rochmah; Khairullah, Aswin Rafif
Jurnal Medik Veteriner Vol. 6 No. 3 (2023): Special Issue: International Conference on Veterinary Medicine and Health Scien
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss3.2023.107-115

Abstract

Burns not only damage skin locally but generally affect the body system and have been related as the secondary cause of death. Burns can be effectively treated with a topical drug to prevent chronic inflammation. Burn wound healing is really important for ensuring overall health and well-being. This study aimed to determine the effect of Sauropus androgynous leaves extract gel on the number of fibroblasts, fibrocytes, and collagen density on burn wound healing in albino rats. A total of 50 male albino rats were randomly divided into five groups i.e. (C-) was normal skin, (C+) was skin burn treated with placebo, (T1) was skin burn treated with 2.5% of S. androgynous leaves extract gel, (T2) was skin burn treated with 5% of S. androgynous leaves extract gel, and (T3) was skin burn treated with 10% of S. androgynous leaves extract the gel. The amount of 25 albino rats' skin samples were collected on the 8th day, and the remaining samples were collected on the 15th day. The results showed that 10% of S. androgynous leaves extract gel improved faster, as indicated by the increased number of fibroblasts, fibrocytes, and collagen density. This study can be concluded that 10% of S. androgynous leaves extract gel was the effective dosage to increase the number of fibroblasts, fibrocytes, and collagen density in burn wound healing.
The Prevalence of Domesticated Geriatri Cats in Surabaya City at April-May 2019 Rahmawati, Rr Indah Nur; Triakoso, Nusdianto; Ma'ruf, Anwar
Journal of Basic Medical Veterinary Vol. 10 No. 1 (2021): Journal of Basic Medical Veterinary, June 2021
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbmv.v10i1.28680

Abstract

This study is beneficial to give information about population of domesticated geriatric cats in Surabaya period from April to May 2019. This study is also beneficial to give information about likely risks of domesticated geriatric cats in Surabaya City based on gender, cat breed, and cat's disease. The design of this study was Observational Retrospective using cross-sectional method. Sampling used stratified random sampling method. This study collected primary data and was analyzed descriptively using prevalence test and relative risks. That domesticated geriatric cats in Surabaya City period from April-May 2019, the oldest cats were written 17 years for male cats and 9 years for female cats. The prevalence of domesticated geriatric cats in Surabaya City period from April-May 2019 was 9 (7,5%). Geriatric cats distributed by the gender were 5 (4,2%) male and 4 (3,3%) female, where geriatric cats distributed by the cat breed were 5 (4,2%) pure breed, 4 (3,3%) mixed breed, and 0 (0%) domestic sample. The result of geriatric cats analysis based on gender showed that male cats had a change of 1,4 times higher compared to the female to reach geriatric, whereas based on cat breed it showed pure breed had a change 3,3 times compared to mixed breed to reach geriatric. On this study, the disease often appeared in domesticated geriatric cats in Surabaya City period from April -May 2019 were: on skin, respiration, digestion, and eyes. Based on relative risk analysis on geriatric cats, it had a change of gastrointetinal tract that was higher compared to other diseases.
BIOACTIVE COMPOUNDS OF Moringa oleifera AS KRASG12C INHIBITORS IN COLORECTAL CANCER: IN SILICO STUDY Marviella, Sephia Tiara; Zulqaida, Salma; Sulisetyawati, Theresia Indah Budhy; Ma'ruf, Anwar
Jurnal Kimia Riset Vol. 9 No. 2 (2024): December
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v9i2.64871

Abstract

KRAS is a GTPase enzyme that regulates cell growth and division. Mutations in KRAS can lead to its permanent activation, resulting in uncontrolled cell growth and cancer progression. Approximately 30–44% of colorectal cancer cases harbor KRAS mutations, with 1–3% involving the KRASG12C variant. Historically considered "undruggable," recent advancements, such as Sotorasib, have demonstrated the potential to target KRASG12C effectively, making it a promising focus for drug discovery. Moringa oleifera, a plant rich in phytochemicals, is a potential source of bioactive compounds with therapeutic applications. In this study, 218 compounds derived from M. oleifera were screened using molecular docking, targeting KRASG12C. Quercetin (3) exhibited the lowest binding affinity (-9.37 kcal/mol) and showed interactions with key residues, including GLN100A, VAL104A, LYS17A, and TYR97A, suggesting a binding mechanism similar to that of Sotorasib as native ligand. The physicochemical analysis further revealed high gastrointestinal absorption, good lipophilicity, and favorable bioavailability scores for Quercetin (3), supporting its potential as a drug candidate. These findings highlight the potential of M. oleifera compounds, particularly quercetin (3), as inhibitors of KRASG12C in colorectal cancer.
IbM bagi Rumah Mocaf Banjarnegara : Pendampingan Kontrol Kualitas Produk Mocaf Ma'ruf, Anwar; Mulyadi, Abdul Haris
ANDAN JEJAMA: Indonesian Journal of Community Engagement (IJCE) Vol. 4 No. 2 (2025): Indonesian Journal of Community Engagement (IJCE) ANDAN JEJAMA
Publisher : FMIPA Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/ijceaj.v4i2.13

Abstract

Permasalahan yang dihadapi Rumah Mocaf Banjarnegara adalah dalam hal control kualitas produk mocaf. Karena proses produksi bersifat massal (masyarakat petani), maka control kualitas sulit untuk dikedalikan. Oleh karena itu diperlukan metode yang praktis dan efisien untuk kontrol kualitas produk mocaf yang diharapkan dapat menjaga kualitas produk mocaf. Penentuan spesifikasi ditentukan nilai yang cukup signifikan berbeda antara tepung mocaf dan tepung tapioka.Tujuan Iptek bagi masyarakat adalah untuk menemukan metode yang praktis dan efisien untuk menentukan kontrol kualitas produk mocaf dan memberi pelatihan kepada masyarakat terkait pengendalian kualitas produk mocaf. Solusi yang ditawarkan secara umum terdiri dari dua bagian utama, yaitu: (1) analisis produk mocaf dan tepung tapioka, dan (2) Penentuan kandungan utama yang menjadi dasar kontrol kualitas produk mocaf, dan (3) memberi pelatihan penentuan kualitas produk mocaf. Analisis kualitas meliputi kandungan HCN, rasio swelling, spectrum FTIR, pasta dan gel properties. Dari hasil pelatihan dapat disimpulkan bahwa kontrol kualitas produk mocaf Rumah Mocaf, dapat memberi pemahaman mitra untuk menjaga mutu produk mocaf yang menggunakan metode klaster pada proses produksinya
Analysis of Differences in Farmer Income Estimation Between Middlemen and Animeter For Bali Cattle in Jaro Subdistrict, Tabalong Regency, South Kalimantan Aulia Rakhman, Muhammad Andika; Soeharsono; Al-Arif, Moh. Anam; Lukiswanto, Bambang Sektiari; Triakoso, Nusdianto; Ma'ruf, Anwar
Media Kedokteran Hewan Vol. 35 No. 2 (2024): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v35i2.2024.146-156

Abstract

This study investigates differences in farmer income and body weight estimation for male and female Bali cattle in extensive farming in Jaro Subdistrict, Tabalong Regency, South Kalimantan. A random sampling approach was used, involving farmers from nine villages. Statistical analyses revealed a significant difference (p < 0.05) in the body weights of male Bali cattle measured by an animeter compared to those estimated by middlemen. In contrast, no significant difference (p > 0.05) was observed for female Bali cattle. These differences significantly impacted farmer income for male cattle because the income estimated by the animeter exceeded that estimated by the middlemen (p < 0.05). However, no significant difference (p > 0.05) was observed between the two estimation methods for female cattle. In addition, no significant relationship was observed between the estimates made by the middlemen and those made by the animeter for both sexes of Bali cattle. This study used the Monte Carlo simulation to predict demand for male and female Bali cattle in 2024. On average, farmers were able to supply between two and three male Bali cattle and between three to seven female Bali cattle per month. To ensure a steady income, farmers are advised to supply at least one male or female Bali cattle. Moreover, farmer groups are encouraged to compensate for cattle shortages or surpluses, thereby ensuring a stable supply for middlemen and consumers.
Co-Authors Abdul Haris Mulyadi Afifah, Dini Nur Agustono, Bodhi Al-Arif, Moh. Anam Alwani Hamad Aulia Rakhman, Muhammad Andika Bambang Sektiari Lukiswanto Ira Sari Yudaniayanti Khairullah, Aswin Rafif Marviella, Sephia Tiara Mirni Lamid Nusdianto Triakoso Panggabean, Rosenna Tiara Putri, Regita Nanda Rahmawati, Rr Indah Nur Rochmah Kurnijasanti Santosa, Arif Prashadi Soeharsono Sulisetyawati, Theresia Indah Budhy Widiyatno, Thomas Valentinus Zulqaida, Salma