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All Journal Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Journal of Global Research in Public Health
Yeti Mareta Undaryati
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Curcumin Protection on Spermatogenic Cells induced by Lead Acetate Yeti Mareta Undaryati; Yogho Prastyo; Fitriya Handayani
Journal of Global Research in Public Health Vol. 4 No. 2 (2019): December
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/jgrph.v4i2.161

Abstract

Curcumin is the most active component of turmeric. Curcumin is a herbal antioxidant that has a protective effect against metal exposure or poisoning such as lead exposure. The aim of this study was to analyze the effect of curcumin administration on lead acetate-induced mice spermatogonia, spermatocytes, and spermatids. Metode: 30 Balb / c mice (Mus musculus), divided into 5 groups. Group K- was the control group, the K + group was the group given lead acetate 0.075 g / KgBW 1x / day for 35 days, the K1 group was the group that was given curcumin 100 mg / KgBW 1x / day for 3 days then continued with 100 mg / day curcumin. KgBW + lead acetate 0.075 g / KgBW 1x / day for 35 days, the K2 group was the group given 200 mg / KgBB curcumin 1x / day for 3 days then continued with curcumin 200 mg / KgBW + lead acetate 0.075 g / KgBB 1x / day for 35 days, and the K3 group was the group that was given curcumin 400 mg / KgBW 1x / day for 3 days then continued with curcumin 400 mg / KgBW + lead acetate 0.075 g / KgBW 1x / day for 35 days Result: The results showed a significant difference in the number of spermatogonia cells in the K + and K2 groups, a significant difference in the number of spermatocytes in the K + and K2 groups, a significant difference in the number of spermatid cells in the K + with K2 and K3 groups.. Conclusion: Curcumin 200 mg / KgBW significantly protects the number of spermatogonia cells, spermatocytes, and spermatids of mice induced by lead acetate.
Literature Review: Effect Of Lead Toxicity On Reproductive System Yeti Mareta Undaryati; Sri Agus Sudjarwo; Reny I’thisom
Journal of Global Research in Public Health Vol. 5 No. 1 (2020): June
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/jgrph.v5i1.202

Abstract

Background: Lead (Pb) is a chemical that belongs to the heavy metal group is bluish grey and is the main pollutants in the environment. The lead that enters the body will be distributed into the blood compound 95% and interfere with the body sistem, one of which is in the reproductive system. The purpose of writing this article is to determine the effects of lead toxicity on the reproductive system. Method: The design of research used is the study of libraries from various sources. The articles are gathered using search engines such as PubMed, Google Schoolar, Science Direct, ProQuest and Elsevier. The article used in the study was published in 2011-2020. Results: Based on the articles collected, it is derived that the consequences of exposure or lead poisoning are disruptive to the body sistem. Disrupted sistems include the reproductive sistem, digestive sistem, cardiovascular sistem and nervous sistem. Reproductive sistem disorders can occur in men and women. In men there can be decreased quality and quantity of sperm, decreased prostate function, decreased testosterone, decreased sexual desire. In women there can be decreased sexual desire, increased cases of infertility, spontaneous abortion, menstrual disorders and stillbirths. Conclusion: Lead poisoning in the reproductive sistem, disorders that can arise are decreased fertility in men and women, increased miscarriage, stillbirth, premature birth, and increased sex desire
Health Problems in Female Reproductive Organs Linda Ayu Setya Indra S; Laura Morani Tamba; Nesti Taileleu; Yeti Mareta Undaryati
Journal of Global Research in Public Health Vol. 9 No. 2 (2024): December
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/jgrph.v9i2.543

Abstract

Women's reproductive health is an important aspect of general health that involves complex organ systems and is susceptible to various disorders. The purpose of this article is to review health problems related to female reproductive organs. By providing comprehensive information on the impact and prevention of these health problems, it is hoped that public awareness of the importance of reproductive health services will increase. Health problems of female reproductive organs such as sexually transmitted infections, non-sexual infections, menstrual disorders, and hormonal disorders. Health problems in the female reproductive system can have a significant impact on quality of life and fertility. If left untreated, these health issues not only impact physical health, but also impact a woman's mental and emotional health, leading to stress related to fertility and overall health. Prevention of sexually transmitted infections (STIs) in women can be done through several effective strategies, including consistent condom use, vaccination against viruses such as Human Papillomavirus (HPV) and Hepatitis B can reduce the risk of infection, comprehensive sexual education, and open communication with partners regarding sexual health history. Women's reproductive health is a vital aspect that affects physical, mental, and social well-being. can experience various health problems. Women's reproductive health problems have an impact. These problems can be prevented to help maintain reproductive health and improve a woman's overall quality of life.
Premenstrual Syndrome (PMS) pada Remaja Putri Anisah Nur Asidah; Elok Dwi Cahyani; Aldhina Janurti; Aulia Rahma; Nadila Afriza; Miftahul Janna; Yeti Mareta Undaryati
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 2 No. 3 (2025): Juli: Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v2i3.1994

Abstract

Background: Premenstrual Syndrome (PMS) is a combination of physical, emotional, and behavioral symptoms that occur cyclically before menstruation and are commonly experienced by adolescent girls. Common symptoms include fatigue, abdominal pain, headaches, anxiety, and mood disturbances, which can affect sleep quality, concentration, and academic productivity. This article provides an in-depth examination of the definition, types, prevalence, causes, impacts, and management of PMS in adolescent girls. Based on epidemiological data, the prevalence of PMS is quite high, both globally and nationally, with incidence rates in Indonesia reaching 70–90% among women of reproductive age, and most cases beginning during adolescence. There are four main types of PMS: Type A (anxiety), Type H (hyperhidrosis), Type C (food cravings), and Type D (depression), each with specific characteristics and etiologies. Causes of PMS include hormonal imbalances of estrogen and progesterone, reduced serotonin levels, poor sleep quality, psychological stress, genetic factors, and unhealthy lifestyles. The impact of PMS on adolescents is complex, including decreased academic performance, social relationship disturbances, and reduced psychological well-being. Therefore, PMS management should be approached holistically through pharmacological (such as NSAIDs, antidepressants, and diuretics) and non-pharmacological (physical exercise, relaxation, lifestyle changes, and nutritional education) interventions. Environmental support and reproductive health education are crucial to help adolescents effectively manage PMS symptoms and improve their quality of life. This study is expected to serve as a foundation for promotive and preventive interventions in adolescent health care.
Update Terbaru Kanker Seviks di Indonesia Asrina Asrina; Nur Azmi Aliya; Ira Pasira; Nur Magfira; Alya Putri Salsadila; Nurul Fadillah; Yeti Mareta Undaryati
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i4.1542

Abstract

Cervical cancer is a significant public health problem globally, including in Indonesia. This disease ranks fourth as the most common cancer in women in the world, with an estimated 604,000 new cases and 342,000 deaths in 2020. Analyzing the current condition of cervical cancer in Indonesia including prevalence, risk factors, impacts, prevention efforts, and treatment based on data to provide a comprehensive picture of the situation of cervical cancer in Indonesia. Cervical cancer is defined as a malignant tumor in the cervix that attacks the epithelial layer and has the potential to spread. Human Papilloma Virus (HPV) infection is the main cause of cervical cancer. In addition, several supporting risk factors include risky sexual behavior, long-term use of oral contraceptives, smoking habits, nutritional deficiencies (especially vitamins C, E, and folic acid), and poor personal hygiene. The Indonesian government has attempted to identify the disease early through the Visual Inspection of Acetic Acid (IVA) method used for early detection of cervical cancer in women aged 30 to 50 years. However, community participation in this program still needs to be improved sustainably. Treatment for cervical cancer can include surgery (eg cryosurgery, LEEP, hysterectomy), radiation, and chemotherapy. Cervical cancer remains a major health challenge in Indonesia. Improved education programs, participation in early detection of IVA, and strengthening of the health system as a whole are needed to effectively reduce morbidity and mortality caused by this disease.
Co-Authors Aldhina Janurti Alya Putri Salsadila Anisah Nur Asidah Asrina Asrina Aulia Rahma Elok Dwi Cahyani Fitriya Handayani Ira Pasira Laura Morani Tamba Linda Ayu Setya Indra S Miftahul Janna Nadila Afriza Nesti Taileleu Nur Azmi Aliya Nur Magfira Nurul Fadillah Reny I’thisom Sri Agus Sudjarwo Yogho Prastyo