Article Per Year (5 Year)
p-Index From 2020 - 2025
1.745
P-Index
This Author published in this journals
All Journal Folia Medica Indonesiana Jurnal Layanan Masyarakat (Journal of Public Service) Journal of Parasite Science Ovozoa: Journal of Animal Reproduction Indian Journal of Forensic Medicine & Toxicology Jurnal Agro Veteriner Journal of Global Research in Public Health
Sri Agus Sudjarwo
Division Of Basic Veterinary Medicine, Faculty Of Veterinary Medicine, Universitas Airlangga, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Decision Sciences, Operations Research & Management Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 9 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 9 Documents
Search

 1 
Nanocurcumin Potential Effect of SOD Enzyme and Caspase-3 Expression in Lead-Acetate Induced Rats Ovarian Granulosa Cells Anis Satus Syarifah; Sri Agus Sudjarwo; Hendy Hendarto; Reny I’tishom; Supriyanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14650

Abstract

Aim: This study investigated the potential effect of nanocurcumin on the increase of SOD enzyme expressionand decrease of caspase-3 in lead acetate-induced rats ovarian granulosa cells.Materials and Methods: Forty five female rats were divided into 5 groups, the negative control group (ratsreceiving corn oil, one hour later receiving distilled water), positive control group (rats receiving corn oil,one hour later receiving lead acetate of 40 mg/kg bw) and experimental groups 1, 2 and 3 (rats receivingnanocurcumin 50 mg, 100 mg and 200 mg/kg bw). One hour after administering the nanocurcumin, therats received 40 mg/kg of lead acetate. All groups received oral treatment once a day for 26 days. Onday 27 the rats were sacrificed and the expression of SOD and caspase-3 enzymes were measured usingimmunohistochemical methods.Results: This study found that lead acetate decreased SOD enzyme expression and increased caspase-3. Incontrast, nanocurcumin increased SOD enzyme and decreased caspase-3 expression in lead acetate-inducedrats ovarian granulosa cells.Conclusion: Nanocurcumin has potential as a strong natural antioxidant by affecting the increase of SODand the decrease of caspase-3 cells in lead acetate-induced rats ovarian granulosa cells.
The Protective Effect of Xanthone via Malondialdehyde and Superoxide DismutaseExpression on Mice Sertoli cell Induced by 2-Methoxyethanol Ernawati; Zufra Inayah; Sri Agus Sudjarwo
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15741

Abstract

The antioxidants can be used for protective in oxidative stress that is one of the important mechanisms of 2-methoxyethanol (2-ME)-induced testis toxicity. The current study was carried out to evaluate The protective effect of xanthone via Malondialdehyde (MDA) and Superoxide Dismutase (SOD) expression on mice Sertoli cell induced by 2-Methoxyethanolon the Sertoli cell number induced by 2-ME in mice. The study used 35 male mice divided into 5 groups: control group (mice were given daily with water purified by distillation); 2-ME group (mice were given daily with 2-ME 200 mg/kg BW orally once in a day for 35 days); and the treatment group ( mice were given the xanthone 60 mg, 120 mg, and 240 mg/kg BW orally once in a day for 38 days, and on the 3th day, were given 2-ME 200 mg/kg BW one hour after the xanthone administration). After 38 days, the testis tissues were collected to evaluate the histological of Sertoli cell number, and also evaluated the immunohistochemical of MDA and SOD expression on Sertoli cell. The result showed that 2-ME administration significantly increased MDA expression, and decreased both SOD expression and the number of Sertoli cells. However, the treatment of xanthone significantly decreased MDA expression, and increased the expression of SOD of the Sertoli cell in the immunohistochemical. Xanthone also significantly increased the Sertoli cell number in histopathological evaluation. In conclusion, From the results of this study demonstrated that xanthone is able to protect Sertoli cell number in mice treated with 2-ME through decreasing MDA and increasing SOD.
EFFECTS OF RED DRAGON FRUIT (Hylocereus polyrhizus) SKIN EXTRACT ON LEAD ACETATE TOXICITY IN THE MORPHOLOGY OF Balb/c MICE (Mus musculus) SPERMATOZOA Rahmawati Raharjo; Sri Agus Sudjarwo; Reny I'tishom
Folia Medica Indonesiana Vol. 53 No. 4 (2017): December 2017
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (187.436 KB) | DOI: 10.20473/fmi.v53i4.7152

Abstract

Red dragon fruit skin extract is used as an antioxidant to lead acetate toxicity. This study aimed to prove the difference in morphology of mice testicular spermatozoa exposed to lead acetate. Twenty-five mice were divided into 5 groups (5 mice per group). K- group was the control group without lead acetate and dragon fruit skin extract administration, K + group was treated with 8 mg/KgBW lead acetate administration for 14 days, P1 group was treated with the administration of 8 mg/KgBW lead acetate for 14 days + 250 mg/kgBW red dragon fruit skin extract for 21 days, P2 group was treated with the administration of 8 mg/KgBW lead acetate for 14 days + 500 mg/kgBW red dragon fruit skin extract for 21 days, and group P3 was a treatment group with the administration of 8 mg/KgBW lead acetate for 14 days + 1000 mg/kgBW red dragon fruit extract for 21 days. The results showed that there was significant difference (P<0.05) in normal sperm morphology among K-, K +, P1, P2, and P3. In conclusion, the administration of red dragon skin extract at a dose of 500 mg/kgBW (P2) is the optimal one which can be used as therapy to increase motility, morphology, and concentration of mice spermatozoa exposed to lead acetate.
Anthelmintic Activity Test of Pare Leaves Extract (Momordica charantia L.) Against Worms Raillietina sp. by In Vitro Trifena Pristi Anindyta; Setiawan Koesdarto; Sri Agus Sudjarwo; Lilik Maslachah; mufasirin mufasirin; Nunuk Dyah Retno Lastuti; Lutfiah Annisa Billa
Journal of Parasite Science (JoPS) Vol. 6 No. 1 (2022): Journal of Parasite Science
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (482.407 KB) | DOI: 10.20473/jops.v6i1.34496

Abstract

The purpose of this research is to prove that pare leaf extract (Momordica charantia L.) has anthelmintic activity against Raillietina sp. in vitro. This study consisted of four treatments and each treatment contained six replications, each of which consisted of six worms. The treatments in this research were K- with 1% CMC-Na, P1 with 2% extract concentration, P2 with 4% extract concentration, P3 with 8% extract concentration. Pare leaf extract has anthelmintic activity against Raillietina sp. in vitro with an effective dose of 8%. The higher the concentration of pare leaf extract, the higher the mortality rate of worms. The longer the immersion time, the higher the number of dead worms.
POTENTIAL OPTIMIZATION OF TOBACCO AGRICULTURE WASTE IN WATUBONANG VILLAGE, BADEGAN DISTRICT, PONOROGO Rochmah Kurnijasanti; Sri Agus Sudjarwo; Kadek Rachmawati
Jurnal Layanan Masyarakat Vol. 7 No. 2 (2023): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v7i2.2023.245-251

Abstract

The aims of this community dedication: 1) Improve the economy of the villagers of Watubonang and Biting, Badegan Ponorogo district through changing mindsets to improve people’s welfare 2) Increasing the knowledge and skills of the villagers of Watubonang and Biting, Badegan Ponorogo district through technology transfer for making pecticide formulations, antiscabies drugs, antiseptik, compost manure disinfectant, dipping solution based on tobacco waste. The result of the communiy dedication implementation showed an increase in participants on how to manufacture various kinds of tobacco waste products from 6.7% to 93.3% and an increase in the skills of participants on how to manufacture various kinds of tobacco waste products from 6.7% to 93.3%. in addition to the increased knwoledge and skills of the community dedication participants in Watubonang and Biting villages, Badegan Ponorogo district, it showed a decrease in the average cost of using medicines, antiseptiks, and disinfectants per house from 210 thousand rupiah to 42 thousand rupiah. Form the results of community dedication in the villages of Biting and Watubonang, Badegan Ponorogo district, it is hoped that they will become fostered villages of FKH Unair.
Histological Features of the Duodenum of Mice (Mus musculus) Treated with Liquid Probiotic Isolates of Bacillus coagulans, Bacillus subtilis, and Saccharomyces cerevisiae Devi Sri Rohmani; Mohammad Anam Al Arif; Sri Agus Sudjarwo; Mohammad Sukmanadi; Eka Pramyrtha Hestianah; Widya Paramita Lokapirnasari
Jurnal Agro Veteriner Vol. 7 No. 2 (2024): Journal Agro Veteriner
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/agrovet.v7i2.57620

Abstract

This study aims to determine the histological description of the height and width of the duodenal villi of mice (Mus musculus) treated with liquid probiotic isolates of Bacillus coagulans, Bacillus subtilis, and Saccharomyces cerevisiae. Histological examination of the duodenum of mice was carried out by making histological preparations from the height and width of the duodenal villi which were observed under a microscope with 100x magnification. Statistical analysis in this study used One-Way ANOVA and Duncan's test. The results showed that the control group and the treatment group had significantly different height and width of the duodenal villi (p<0.05). The conclusion of this study is that the administration of isolates Bacillus coagulans, Bacillus subtilis, and Saccharomyces cerevisiae can increase the height and width of the duodenal villi of mice and the P2 group with a dose of 0.27 mL/kg BW has the greatest average value for the height and width of the duodenal villi with an average height of 360.80 μm and an average width of 152.30 μm.
Literature Review: Effect Of Lead Toxicity On Reproductive System Yeti Mareta Undaryati; Sri Agus Sudjarwo; Reny I’thisom
Journal of Global Research in Public Health Vol. 5 No. 1 (2020): June
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/jgrph.v5i1.202

Abstract

Background: Lead (Pb) is a chemical that belongs to the heavy metal group is bluish grey and is the main pollutants in the environment. The lead that enters the body will be distributed into the blood compound 95% and interfere with the body sistem, one of which is in the reproductive system. The purpose of writing this article is to determine the effects of lead toxicity on the reproductive system. Method: The design of research used is the study of libraries from various sources. The articles are gathered using search engines such as PubMed, Google Schoolar, Science Direct, ProQuest and Elsevier. The article used in the study was published in 2011-2020. Results: Based on the articles collected, it is derived that the consequences of exposure or lead poisoning are disruptive to the body sistem. Disrupted sistems include the reproductive sistem, digestive sistem, cardiovascular sistem and nervous sistem. Reproductive sistem disorders can occur in men and women. In men there can be decreased quality and quantity of sperm, decreased prostate function, decreased testosterone, decreased sexual desire. In women there can be decreased sexual desire, increased cases of infertility, spontaneous abortion, menstrual disorders and stillbirths. Conclusion: Lead poisoning in the reproductive sistem, disorders that can arise are decreased fertility in men and women, increased miscarriage, stillbirth, premature birth, and increased sex desire
Reproductive Performance of Crossbreed Cows on Lowland Terrain Ardiyansyah, Septiana Alafia Yusi; Sri Agus Sudjarwo; Nusdianto Triakoso; Tri Wahyu Suprayogi; Ismudiono Ismudiono; Oky Setyo Widodo
Ovozoa: Journal of Animal Reproduction Vol. 12 No. 3 (2023): Ovozoa: Journal of Animal Reproduction
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ovz.v12i3.2023.124-130

Abstract

This study aims to identify the differences in reproduction performance of Ongole cross (PO), Limousine cross (Limpo), and Simmental cross (Simpo) in Kerek district, Tuban regency. Primary data was taken by interviewing inseminators and farmers, while secondary data was taken from the Fisheries and Animal Husbandry Department of Tuban regency. The total sample was 360 cows consisting of 30 PO, Limpo, and Simpo cows aged 3, 4, 5, and 6 years respectively which were calculated based on the Roscoe formula. Data was analyzed using the Simple Linear Regression and ANOVA followed by Duncan's multiple range test at a significance level of 95%. The results showed that the services per conception (S/C), conception rate (CR), and calving rate (CvR) were not significantly different (p >0.05) between PO, Limpo and Simpo cows. Meanwhile, days open (DO) and fertility status (FS) of PO cows were higher (p <0.05) than Limpo and Simpo cows. There was no significant difference (p >0.05) in DO and FS between Limpo and Simpo cows. The linear equation with age as a predictor (X) of S/C, DO, and CI (Y) values were not significant (p >0.05) in PO, Limpo, and Simpo cows. It could be concluded that the reproductive performance of PO cows was better than Limpo and Simpo cows.
Effect of white guava (Psidium guajava L.) fruit juice on the quality of lead acetate induced rats (Rattus norvegicus) spermatozoa Alifia, Annisa; Sri Mulyati; Wurlina Wurlina; Tatik Hernawati; Budi Utomo; Soeharsono Soeharsono; Sri Agus Sudjarwo; Muhammad Thohawi Elziyad Purnama
Ovozoa: Journal of Animal Reproduction Vol. 12 No. 3 (2023): Ovozoa: Journal of Animal Reproduction
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ovz.v12i3.2023.131-140

Abstract

This study aims to determine the effect of the administration of white guava (Psidium guajava L.) fruit juice on spermatozoa plasma membrane integrity (PMI), morphological abnormality, viability, and motility of lead acetate induced rats (Rattus norvegicus). Twenty-five male rats were divided into five groups: NC (negative control) group, rats were administered with distilled water twice daily at four-hour intervals; T0 (positive control) group, rats were administered daily with lead acetate 50 mg/kg bw and distilled water four hours later; T1, T2, and T3 groups, rats were administered daily with lead acetate 50 mg/kg bw and 0.5 mL of 25, 50, and 100% white guava fruit juice four hours later. The treatment of the rats was conducted for 14 days, and on day 15, all rats were sacrificed to assess the spermatozoa quality. Data was analyzed using ANOVA followed by Duncan's multiple range test at a confidence level of 95%. The results showed that exposure to lead acetate (T0) caused lower spermatozoa PMI, viability, and motility as well as higher spermatozoa morphological abnormalities (p <0.05) compared to those of the T0 group. Administration of white guava fruit juice starting at a dose of 25% (T1) resulted in higher spermatozoa motility, viability, and PMI as well as lower spermatozoa morphological abnormalities (p <0.05) compared to rats in the T0 group. It could be concluded that white guava fruit juice maintained the spermatozoa quality of lead acetate induced rats.
Co-Authors Al arif, Mohammad Anam Alifia, Annisa Ardiyansyah, Septiana Alafia Yusi BUDI UTOMO Devi Sri Rohmani Eka Pramyrtha Hestianah Ernawati Hendy Hendarto I'tishom, Reny Ismudiono Ismudiono Kadek Rachmawati Lilik Maslachah Lutfiah Annisa Billa Mohammad Sukmanadi Mufasirin Muhammad Thohawi Elziyad Purnama Nunuk Dyah Retno Lastuti Nusdianto Triakoso Raharjo, Rahmawati Reny I’thisom Rochmah Kurnijasanti Salsabila, Unik Hanifah Setiawan Koesdarto Soeharsono Soeharsono Sri Mulyati Syarifah, Anis Satus Tatik Hernawati Tri Wahyu Suprayogi Trifena Pristi Anindyta Widodo, Oky Setyo Widya Paramita Lokapirnasari Wurlina, W Yeti Mareta Undaryati Zufra Inayah