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Hemoglobin Levels and Number of Erythrocytes in Scabies-infected Male Mice (Mus musculus) Treated with Water Extract of Taro (Colocasia esculenta (L.) Schott Cultivar Hideung Widhyastini, I Gusti Ayu Manik; Nia Yuliani; Ananda Sarah Nur Azizah
Sains Natural: Journal of Biology and Chemistry Vol. 14 No. 1 (2024): Sains Natural
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31938/jsn.v14i1.694

Abstract

This study aims to analyze the hemoglobin levels and number of erythrocytes in scabies-infected male mice treated with taro water extract as a cheap and safe alternative treatment for scabies. The test animals were 24 mice weighing 20-25 grams, divided into 6 groups consisting of: K1: taro water extract 100gr/100 ml water, K2 taro water extract 200gr/100ml water, K3: using 300gr/100ml taro water extract water, K4: ivermectin positive control, K5: negative control with water alone, and K6 normal control not infected with scabies and not given treatment. The application of taro extract was carried out for five days. Observations were carried out every day, until day 7. Blood samples were taken from mice three times: before being infected with scabies (healthy), when infected with scabies, and after being treated with taro water extract. The data obtained was processed statistically using the SPSS software with the One Way ANOVA test. Sarcoptes scabiei infection affects the appearance of the blood profile of male mice when infected, there is an increase in the number of erythrocytes but does not affect hemoglobin levels. Treatment with water extract of the taro (Colocasia esculenta (L.) Schott) cultivar hideung in different concentrations did not show significant blood results, but it could heal wounds caused by scabies infection.
Phytochemical Composition of Sonneratia alba Mangrove Leaves and Fruits:  Opportunities for Functional Food, Herbal Medicine, and Forest Conservation I Gusti Ayu Manik Widhyastini; Messalina Lovenia Salampessy; Ni Gusti Ayu Manik Ermayanti
Forest and Nature Vol. 1 No. 3 (2025): July
Publisher : Green Insight Solutions

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63357/fornature.v1i3.14

Abstract

Mangrove ecosystems are vital coastal habitats that provide ecological, economic, and medicinal benefits. Sonneratia alba, a dominant mangrove species in Muara Gembong, Indonesia, is traditionally utilized for food products and herbal remedies; however, limited studies have compared its organ-specific phytochemical profiles. This study investigates the qualitative composition of secondary metabolites in the leaves and fruits of S. alba using 96% ethanol extracts and standard phytochemical screening methods. The results revealed that both plant parts contained saponins, tannins, phenolics, flavonoids, and glycosides, while triterpenoids were exclusively detected in the leaves, and steroids were absent in both organs. These findings highlight distinct organ-specific variations in secondary metabolites, suggesting that leaves may possess greater therapeutic potential than fruits. The identified bioactive compounds exhibit antioxidant, anti-inflammatory, antimicrobial, and anticancer properties, underscoring their relevance for natural drug discovery and the development of functional foods. Moreover, promoting the pharmacological value of S. alba contributes to enhancing community awareness and participation in mangrove conservation. This study provides a scientific basis for future exploration of targeted bioactivity and sustainable utilization of S. alba in coastal ecosystem management.