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PENGEMBANGAN HEURISTIK DIFERENSIAL TERKOMPRESI UNTUK ALGORITMA BLOCK A* Wicaksono, Teguh Budi; Munir, Rinaldi
JUTI: Jurnal Ilmiah Teknologi Informasi Vol 10, No 2, Juli 2012
Publisher : Department of Informatics, Institut Teknologi Sepuluh Nopember

Kami menawarkan sebuah optimasi dari fungsi heuristik diferensial terkompresi untuk algoritma Block A*. Optimasi yang ditawarkan berupa optimasi dari segi memori dan performa pencarian yang diukur berdasarkan jumlah simpul yang dikembangkan. Hasil dari optimasi ini menunjukkan bahwa optimasi yang kami tawarkan dapat mengurangi jumlah penggunaan memori walau dengan sedikit penurunan performa pencarian.

Terapi Saat Ini untuk Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): Sebuah Literature Review Hunaifi, Ilsa Hunaifi; Wicaksono, Teguh Budi; Nugraha, Gede Rama Hardy; Maulida, Rizka Ayu; Kusumadewi, Rima Cahyati; Pratiwi, Rukmanggana Satya; Amaliya, Annisa Risqi; Sepestian, Ghina Shadrina Rienti
JURNAL SAINS TEKNOLOGI & LINGKUNGAN Vol. 10 No. 3 (2024): JURNAL SAINS TEKNOLOGI & LINGKUNGAN
Publisher : LPPM Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jstl.v10i3.619

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disease. The European Academy of Neurology recommends treatment using corticosteroids, immunoglobulin, plasma exchange, & other treatments as treatment options for chronic inflammatory demyelinating polyradiculoneuropathy. However, several studies in recent years have shown that there is potential in the treatment of chronic inflammatory demyelinating Polyradiculoneuropathy. The aim of this literature review is to provide the latest therapy for chronic inflammatory demyelinating polyradiculoneuropathy based on guidelines as well as other information therapy alternatives. The method used in this literature review uses searches in several databases. The results of several studies show the development of chronic inflammatory demyelinating polyradiculoneuropathy therapy both pharmacologically & non-pharmacologically. The development of therapy for chronic inflammatory demyelinating polyradiculoneuropathy, namely hematopoietic stem cells & spinal cord stimulation, shows potential as a therapeutic option for patients with chronic inflammatory demyelinating polyradiculoneuropathy.

Getting to Know More about Tetanus Faqih, Fauzan; Aritiah, M. Awalul Rizky; Solihatin, Illiyani; Afifah, Fiza; Faranajhia, Hagia; Wicaksono, Teguh Budi; Irmayanto, Tomi
PROMOTOR Vol. 8 No. 3 (2025): JUNI
Publisher : Universitas Ibn Khaldun Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/pro.v8i3.1188

Tetanus is an acute disease that affects the central nervous system caused by tetanospasmin toxin produced by Clostridium tetani. Tetanus is a deadly disease in developing countries, killing approximately 500,000 people per year. This is due to lack of hygiene, easy contamination, poor wound care, lack of public awareness of the importance of hygiene and tetanus vaccination. In general, tetanus is characterized by rigidity, muscle spasm and autonomic disorders. Spasms almost always occur in the neck and jaw muscles causing jaw closure (trismus, lockjaw) and involve not only the extremity muscles, but also the trunk muscles. Tetanus is not transmitted from human to human and can be prevented through immunization. Clostridium tetani is quite widespread in nature and cannot be eradicated. To reduce the number of cases, tetanus treatment efforts focus on prevention using vaccination with active immunization or passive immunization and post-exposure care.

Current Therapies for Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A Literature Review Wicaksono, Teguh Budi; Nugraha, Gede Rama Hardy; Maulida, Rizka Ayu; Kusumadewi, Rima Cahyati; Pratiwi, Rukmanggana Satya; Amaliya, Annisa Risqi; Sepestian, Ghina Shadrina Rienti; Hunaifi, Ilsa
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7395

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disease. The European Academy of Neurology recommends treatment using corticosteroids, immunoglobulin, plasma exchange, & other treatments as treatment options for chronic inflammatory demyelinating polyradiculoneuropathy. However, several studies in recent years have shown that there is potential in the treatment of chronic inflammatory demyelinating Polyradiculoneuropathy. The aim of this literature review is to provide the latest therapy for chronic inflammatory demyelinating polyradiculoneuropathy based on guidelines as well as other information therapy alternatives. The method used in this literature review uses searches in several databases. The results of several studies show the development of chronic inflammatory demyelinating polyradiculoneuropathy therapy both pharmacologically & non-pharmacologically. The development of therapy for chronic inflammatory demyelinating polyradiculoneuropathy, namely hematopoietic stem cells & spinal cord stimulation, shows potential as a therapeutic option for patients with chronic inflammatory demyelinating polyradiculoneuropathy.

Marine Organisms with Anti-Amyloid Effect Through Their Role as BACE1 Inhibitors for Preventive Effort in Alzheimer’s Disease: A Literature Review Putra, Made Raditya Arhya; Saputri, Legis Ocktaviana; Wicaksono, Teguh Budi; Nugraha, Kadek Nandita; Putri, Ajeng Ayu; Salsabila, Rika Kamila; Fidelia, Puspa Zalika
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7546

Alzheimer’s Disease (AD) is a gradually worsening neurodegenerative condition characterized by the build-up of beta-amyloid proteins, resulting in a decline in cognitive abilities. β-site amyloid precursor protein cleaving enzyme-1 (BACE1) is known to play a role in the formation of beta-amyloid plaques. Thus, theoretically, inhibiting BACE1 can potentially prevent and slow down the accumulation of these plaques. This study is a literature review that compiles data from various research examining the inhibitory effects of compounds from marine organisms on the BACE1 enzyme. A comprehensive analysis was conducted on the available literature to evaluate the potential of these compounds. 19 marine organisms and 40 compounds were identified with low IC50 values, five compounds with notably low IC50 values were identified: (1) 8,8’-Bieckol [1.62 µM] from Ecklonia cava, (2) Phlorofucofuroeckol A [2.13 µM] and (3a) Dieckol [2.21 µM] from Eisenia bicyclis, (4) bis-(2,3,6-tribromo-4,5-dihydroxybenzyl) ether [2.32 µM] from Symphyocladia latiuscula, (3b) another Dieckol [2.34 µM] also from Ecklonia cava and (5) Heparan sulfate [2.89 µM] from Portunus pelagicus. These findings underscore the therapeutic potential of marine compounds as BACE1 inhibitors for AD. However, further research is needed to explore their bioavailability and clinical efficacy for practical application in preventing and treating Alzheimer’s Disease.

PENGENALAN KESEHATAN REPRODUKSI DAN PENCEGAHAN INFEKSI MENULAR SEKSUAL DI SMPN 2 DAN SMPN 6 MATARAM Octora, Metta; Danianto, Ario; Adni, Azizatul; Prihatina, Lale Maulin; Lasiaprillianty, Intan Wahyu; Wicaksono, Teguh Budi
Jurnal Abdi Insani Vol 11 No 2 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i2.1275

Teenager reproductive health is a health problem that concerns the nation's next generation, with high vulnerability to sexually transmitted infections (STIs). About 1 million transmissions of STIs, such as chlamydia, gonorrhea, syphilis and trichomoniasis occur every day worldwide, and the majority are asymptomatic. Every year, it is estimated 374 million cases are predominantly of reproductive age. This program is based on the trend increasing of promiscuous sexual relations among junior high school teenagers which results in early pregnancy and transmission of STIs. This program has purpose to increase the knowledge of junior high school students and teachers regarding sexually transmitted infections and reproductive health as well as preventing free sex. Counseling regarding reproductive health and sexually transmitted infections is carried out at SMPN 2 and SMPN 6 in Mataram. Extension activities include providing outreach materials, interactive question and answer sessions, Instagram competitions on related topics. The mean post-test score of participants was significantly higher than the pre-test (p <0.05). The scores of SMPN 6 students were found to have a significant increase in the mean during the post-test compared to the pre-test (p <0.05). There was a change in the knowledge of SMPN 2 and SMPN 6 Mataram students regarding reproductive health and STIs after the counseling

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