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Anatomical and Physiological Characteristics of Neonatal and Infant Skin: Effects on Immunity and Dermatitis Prevalence Mario, Andina Nabilah; Girsang, Andrew Deardo Purba; Srigede, Baiq Kayla; Hadiyati, Fathmi; Pramudya , I Nengah Andra Putra; Saraswati, Ni Wayan Citra Ayu; Helmiana, Putri Fatimah; Pramudia, Prananda Rizki; Fildzani, Qashrina Vania; Nurhidayati; Tarigan, Rizky Agung Fatahillah
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7918

Abstract

The skin has an important role in protecting the human body. However, in infants, the skin has a structure and function that are not fully mature yet, making infants vulnerable to various skin disorders. This article aims to review the structure, function, and development of infant skin, as well as the common diseases that occur in infant skin, including the causes, pathophysiology, and management. A literature review was conducted using scientific articles related to these topics. The review results show that infant skin has a different structure compared to adult skin, and the maturation of its structure and function occurs gradually. Infant skin is protected by the microbiota and the primary immune system. Common skin diseases in infants, such as dermatitis, are caused by an interaction between genetic and environmental factors, and involve the activation of skin cells, the release of mediators, and an immune response. A good understanding of the structure, function, and skin diseases of infants is very important for making the right diagnosis and management, so that the quality of life of infants can be maintained.
Pathophysiology of Rabies Encephalitis and Treatment of Rabies : A Literature Review Ginuluh, Gintis Dhimar; Kamila, Alya Syafa; Humam, Anang Muh Naufal; Helmiana, Putri Fatimah; Pratiwi, Rukmanggana Satya; Hunaifi, Ilsa; Arsy, Lazuardi
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7951

Abstract

Rabies is a zoonotic disease transmitted by the saliva of mammals infected with Rabies lyssavirus. Rabies is a lethal disease that is still a health problem in Indonesia. This article aims to review the clinical features, diagnosis, pathophysiology, and management of rabies. This research collects and analyzes literature related to rabies that was conducted through Google Scholar, Pubmed, and ScienceDirect. The review results show that rabies with clinical features, especially rabies encephalitis had poor outcomes. Rabies is a neurotropic virus that spreads through neurons and attack CNS causing rabies encephalitis. The management is categorized into pre-exposure treatment, post-exposure treatment, and palliative treatment. An understandable information regarding the mechanism of rabies encephalitis and rabies management is very important to minimize deaths caused by rabies.