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All Journal Jurnal Biologi Tropis
Kusuma, I Gusti Ketut Artha Jaya
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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The Incidence of Depression in Elderly Patients with Hypertension Stage 2 in Karang Taliwang Tantowi, Natalia; Wedayani, Anak Agung Ayu Niti; Pujiarohman, Pujiarohman; Adni, Azizatul; Kusuma, I Gusti Ketut Artha Jaya
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8804

Abstract

Depression is a common mental health disorder in the elderly, often coexisting with chronic conditions like hypertension. This study examines the relationship between depression and hypertension stage 2 among elderly individuals at Puskesmas Karang Taliwang, considering age and gender. A cross-sectional study of 30 elderly patients used a validated questionnaire to assess depressive symptoms. Results showed a significant association between age (≥60 years) and depression, while gender had no statistical correlation. Hypertension stage 2 was also significantly linked to depression, though with a small effect size. These findings highlight the need for integrated healthcare strategies addressing both mental and cardiovascular health in the elderly. Further research is needed to explore underlying mechanisms and potential interventions.
Osteochondroma: A Literature Review with Case Illustrations Firdaus, Nadine Aisyah Sultan; Aliyyu, Aisah; Zubaedi, Alisha Chaerani; Prawiro, Aurellia Wongso; Remtaya, Baiq; Rameci, Hadil Hudati Awwari; Aghni, Hasna Tazkia; Kusuma, I Gusti Ketut Artha Jaya; Ramadhan, Panji Sena; Mikailla, Romy Healthy
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10183

Abstract

Osteochondroma is the most common benign bone tumor, typically discovered during periods of skeletal growth. Although frequently asymptomatic, it may cause pain, deformity, neurovascular compression, or in rare instances undergo malignant transformation into secondary chondrosarcoma. This study presents a case-based literature review to illustrate the spectrum of clinical manifestations, diagnostic approaches, and management strategies of osteochondroma. Three representative cases were analyzed: a 52-year-old female with talar osteochondroma presenting with ankle pain and swelling; a 17-year-old male with distal femoral osteochondroma manifesting as a posterior thigh mass with minimal symptoms; and a 26-year-old female with Hereditary Multiple Exostoses (HME) who developed secondary chondrosarcoma. The comparison highlights that solitary lesions are often managed effectively with simple excision, while HME carries a higher risk of malignant transformation requiring more complex interventions, such as total hip replacement and adjuvant radiotherapy. Overall, osteochondroma generally has an excellent prognosis; however, careful evaluation and long-term monitoring are crucial, particularly in patients with HME.
Effectiveness of Artificial Wistar Rat Cage Size in Accelerating The Occurrence of Dysplasia in The Process of Formaldehyde Induction Kusuma, I Gusti Ketut Artha Jaya; Anak Agung Ayu Niti Wedayani; Restuningdyah, Novia Andansari Putri; Wiguna, Putu Aditya
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8172

Abstract

Cage is a medium used in placing experimental animals in experimental-based studies to serve as learning instruments related to studying the cause and effect to be investigated. The size of the cage can affect several health factors in experimental animals, such as the social level and stress level of the animal. Formaldehyde is a carcinogenic compound that can cause malignancies if exposed continuously to living things. Therefore, the purpose of this study was to determine whether cage size can affect the degree of dysplasia in Wistar rats induced by 40 ppm formaldehyde. This study is a quantitative study that uses a true experimental research design with post-test only control group design. This study used male Wistar rats (Rattus norvegicus) with a total of 15 rats divided into 3 groups, namely, a small cage group with a size of (27.5 x 21.5 x 9) cm3, a medium cage group with a size of (28 x 22.5 x 10) cm3, and a large cage group with a size of (30 x 24 x 11.5) cm3 with a total of 4 treatment rats (formaldehyde 40 ppm) and 1 control rat (untreated) in each group. The treatment given to rats was carried out 6 hours per day and lasted for 12 weeks until all rats were terminated at the same time. The rats were terminated and histopathological observations were made to assess the degree of dysplasia that occurred. The results of the Kruskal-Wallis statistical test showed a significant relationship (p < 0.05). This study shows that there is a relationship between the size of artificial cages and the degree of dysplasia in Wistar rats induced by 40 ppm formaldehyde.
Co-Authors Aghni, Hasna Tazkia Aliyyu, Aisah Anak Agung Ayu Niti Wedayani Azizatul Adni Firdaus, Nadine Aisyah Sultan Mikailla, Romy Healthy Prawiro, Aurellia Wongso Pujiarohman, Pujiarohman Putu Aditya Wiguna Ramadhan, Panji Sena Rameci, Hadil Hudati Awwari Remtaya, Baiq Restuningdyah, Novia Andansari Putri Tantowi, Natalia Zubaedi, Alisha Chaerani