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Rameci, Hadil Hudati Awwari
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Osteochondroma: A Literature Review with Case Illustrations Firdaus, Nadine Aisyah Sultan; Aliyyu, Aisah; Zubaedi, Alisha Chaerani; Prawiro, Aurellia Wongso; Remtaya, Baiq; Rameci, Hadil Hudati Awwari; Aghni, Hasna Tazkia; Kusuma, I Gusti Ketut Artha Jaya; Ramadhan, Panji Sena; Mikailla, Romy Healthy
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10183

Abstract

Osteochondroma is the most common benign bone tumor, typically discovered during periods of skeletal growth. Although frequently asymptomatic, it may cause pain, deformity, neurovascular compression, or in rare instances undergo malignant transformation into secondary chondrosarcoma. This study presents a case-based literature review to illustrate the spectrum of clinical manifestations, diagnostic approaches, and management strategies of osteochondroma. Three representative cases were analyzed: a 52-year-old female with talar osteochondroma presenting with ankle pain and swelling; a 17-year-old male with distal femoral osteochondroma manifesting as a posterior thigh mass with minimal symptoms; and a 26-year-old female with Hereditary Multiple Exostoses (HME) who developed secondary chondrosarcoma. The comparison highlights that solitary lesions are often managed effectively with simple excision, while HME carries a higher risk of malignant transformation requiring more complex interventions, such as total hip replacement and adjuvant radiotherapy. Overall, osteochondroma generally has an excellent prognosis; however, careful evaluation and long-term monitoring are crucial, particularly in patients with HME.
Literature Review: Pathophysiology, Clinical Features and Management of Cor Pulmonale Rameci, Hadil Hudati Awwari; Maya, Elyana Labib; Fauzan, Naufal Revaldy; Pambudi, Novanda Ayu Dila Putri; Anugrah, Yunan Prabu Jaya
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10357

Abstract

Cor pulmonale refers to a condition affecting the right ventricle of the heart due to increased pulmonary pressure causing dilation or hypertrophy. This article was compiled using a literature review method. This disorder can manifest acutely, often triggered by a massive pulmonary embolism, severe pneumonia, or Acute Respiratory Distress Syndrome (ARDS), or chronically, usually caused by Chronic Obstructive Pulmonary Disease (COPD), pulmonary fibrosis, bronchiectasis, sleep apnea, or obesity-related hypoventilation syndrome. The primary cause is a disturbance in ventilation-perfusion balance that progresses to pulmonary hypertension. Symptoms usually appear in the advanced stages and include shortness of breath, fatigue, weakness, fainting with exertion, chest discomfort, abdominal swelling, lower extremity edema, wheezing, and coughing. Diagnostic evaluation includes chest radiography, computed tomography (CT scan), electrocardiography (ECG), and cardiac catheterization, the latter being the definitive method. Treatment strategies aim to correct hypoxemia, relieve right ventricular strain, and address the underlying cause of the condition.
Co-Authors Aghni, Hasna Tazkia Aliyyu, Aisah Anugrah, Yunan Prabu Jaya Fauzan, Naufal Revaldy Firdaus, Nadine Aisyah Sultan Kusuma, I Gusti Ketut Artha Jaya Maya, Elyana Labib Mikailla, Romy Healthy Pambudi, Novanda Ayu Dila Putri Prawiro, Aurellia Wongso Ramadhan, Panji Sena Remtaya, Baiq Zubaedi, Alisha Chaerani