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All Journal Jurnal Biologi Tropis
Ramadhan, Panji Sena
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Functional Disorders of the Biliary System: Biliary Dyskinesia and Sphincter of Oddi Dysfunction Mikailla, Romy Healthy; Wulandari, Baiq Nurhandini; Wardana, Shira Putri; Firdaus, Nadine Aisyah Sultan; Ramadhan, Panji Sena; Aghni, Hasna Tazkia; Nurhidayati, Nurhidayati
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.9955

Abstract

Functional biliary disorders are conditions caused by biliary dysmotility without the presence of gallstones, sludge, microlithiasis, or microcrystalline disease. The most common functional biliary disorders are biliary dyskinesia and sphincter of Oddi dysfunction. This study employed a literature review method by searching and reviewing various references from online databases such as PubMed, Google Scholar, and ProQuest. Functional biliary disorders such as biliary dyskinesia and sphincter of Oddi dysfunction often cause biliary pain without gallstones. Although not life-threatening, these disorders can affect quality of life and require appropriate management. Pharmacological treatments such as NSAIDs and ursodeoxycholic acid (UDCA) can help alleviate symptoms of biliary disorders, but surgical interventions such as cholecystectomy and sphincterotomy may be necessary for more severe cases. The choice of treatment method should take into account the risks and complications, and be carried out by an experienced medical team.
Osteochondroma: A Literature Review with Case Illustrations Firdaus, Nadine Aisyah Sultan; Aliyyu, Aisah; Zubaedi, Alisha Chaerani; Prawiro, Aurellia Wongso; Remtaya, Baiq; Rameci, Hadil Hudati Awwari; Aghni, Hasna Tazkia; Kusuma, I Gusti Ketut Artha Jaya; Ramadhan, Panji Sena; Mikailla, Romy Healthy
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10183

Abstract

Osteochondroma is the most common benign bone tumor, typically discovered during periods of skeletal growth. Although frequently asymptomatic, it may cause pain, deformity, neurovascular compression, or in rare instances undergo malignant transformation into secondary chondrosarcoma. This study presents a case-based literature review to illustrate the spectrum of clinical manifestations, diagnostic approaches, and management strategies of osteochondroma. Three representative cases were analyzed: a 52-year-old female with talar osteochondroma presenting with ankle pain and swelling; a 17-year-old male with distal femoral osteochondroma manifesting as a posterior thigh mass with minimal symptoms; and a 26-year-old female with Hereditary Multiple Exostoses (HME) who developed secondary chondrosarcoma. The comparison highlights that solitary lesions are often managed effectively with simple excision, while HME carries a higher risk of malignant transformation requiring more complex interventions, such as total hip replacement and adjuvant radiotherapy. Overall, osteochondroma generally has an excellent prognosis; however, careful evaluation and long-term monitoring are crucial, particularly in patients with HME.
Clinical Status Asthmaticus as a Respiratory Emergency: Management in Pediatric and Adult Populations Ramadhan, Panji Sena; Nursiain, Aziza Chantiqka Aulia; Wardana, Shira Putri; Salsabila, Tsania Zulfa; Larasati, Anak Agung Ayu Regina
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10780

Abstract

Status asthmaticus is a life-threatening acute asthma exacerbation that fails to respond to initial standard therapy and requires prompt, protocol-based emergency care. This article aims to determine the clinical status of asthma as a respiratory emergency: management in pediatric and adult populations. The article was compiled using a Systematic Literature Review (SLR) approach, combining current evidence and clinical guideline recommendations regarding the management of status asthmaticus in pediatric and adult populations. Status asthmaticus is a form of severe asthma exacerbation that is an emergency because it can lead to respiratory arrest and death if not treated promptly. Patients generally present with complaints of progressive shortness of breath, cough, wheezing, and signs of respiratory failure such as tachypnea, accessory muscle retractions, and in severe cases, decreased consciousness. Symptoms in children are usually more dramatic due to narrower airways, while in adults the main risks are respiratory muscle fatigue and ventilation complications. Initial management includes airway stabilization, oxygen administration, and immediate initiation of a short-acting bronchodilator (nebulized beta-agonist/MDI). If improvement does not occur, inhaled anticholinergics and systemic corticosteroids are added. Thus, in both children and adults, status asthmaticus requires early recognition, rapid treatment, and close evaluation until the condition is fully stabilized. Continuous monitoring with pulse oximetry and arterial blood gas analysis is emphasized as essential for detecting deterioration. Early recognition and rapid escalation following standard emergency pathways are crucial to reducing morbidity and mortality in both age groups.
Co-Authors Aghni, Hasna Tazkia Aliyyu, Aisah Firdaus, Nadine Aisyah Sultan Kusuma, I Gusti Ketut Artha Jaya Larasati, Anak Agung Ayu Regina Mikailla, Romy Healthy Nurhidayati Nurhidayati Nursiain, Aziza Chantiqka Aulia Prawiro, Aurellia Wongso Rameci, Hadil Hudati Awwari Remtaya, Baiq Salsabila, Tsania Zulfa Wardana, Shira Putri Wulandari, Baiq Nurhandini Zubaedi, Alisha Chaerani