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All Journal PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Borneo Journal of Pharmacy
Rahman, Ave
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Agriculture, Biological Sciences & Forestry Economics, Econometrics & Finance Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Inovasi Produk Olahan Tahu dan Pengemasannya serta Pengembangan Pemasaran dalam Upaya Meningkatkan Pendapatan Perajin Tahu di Desa Karanganyar Kecamatan Wates Kabupaten Kediri: Innovation in Processed Tofu Products and Their Packaging and Marketing Development in an Effort to Increase the Income of Tofu Crafters in Karanganyar Village, Wates District, Kediri Regency Purwanto, Bambang Tri; Ekowati, Juni; Widiandani, Tri; Hariyadi, Dewi Melany; Hendradi, Esti; Yusuf, Helmy; Purnomo, Ahmad Toto; Ramadhani, Firmansyah Ardian; Siswandono, Siswandono; Wiyono, Anang Setyo; Yuliati, Ninis; Kristianingsih, Ida; Savitri, Orchidea Meidy Nurintan; Maulia, Arwinda; Rahman, Ave
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 11 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i11.8698

Abstract

MSMEs in the food sector are among the main supporters of Indonesia's economic activities. As a food production center in the form of tofu products, Kediri Regency is well known to the public, with white, yellow, silk, and other tofu products. Most of the tofu production carried out to date is only in the form of tofu products in their original form. This is because tofu craftsmen have not utilized other processed tofu products to increase their income. This community service activity aims to introduce innovations in processed tofu products, packaging, marketing, and processing of liquid tofu waste into new products which are expected to increase the income of tofu makers in Karanganyar village, Wates District, Kediri Regency. This community service activity was carried out using the media of presenting several materials and carrying out two-way interactive discussions. Evaluation of this activity was carried out with pre- and post-tests from the participants by answering 10 questions related to the three materials. The results obtained after being analyzed using the SPSS program showed differences between the pre-and post-tests of the participants, whereas the post-test results showed that the participants had understood the material provided during this activity. Thus, it can be concluded that this activity can be proven to be understood by the participants regarding innovation in processed tofu products and processing of tofu liquid waste.
Molecular Docking Study of Illicium verum Hook f. as Elastase and Collagenase Inhibitor in Anti-aging Mechanism Rahman, Ave; Widiandani, Tri; Widyowati, Retno
Borneo Journal of Pharmacy Vol. 8 No. 2 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i2.9574

Abstract

Skin aging, a natural physiological process intensified by external factors that augment the activity of aging-related enzymes such as elastase and collagenase, leads to the degradation of collagen solubility and the disruption of elastin fiber cross-linking. This study aimed to investigate the potential of secondary metabolites from Illicium verum fruit as inhibitors of both elastase and collagenase through an in silico molecular docking approach. The methodology involved ligand and protein preparation, validation of the docking protocol, the molecular docking simulation itself, and subsequent visualization of amino acid residue interactions. The protein targets utilized were elastase (PDB ID: 1Y93) and collagenase (PDB ID: 2D1N). The docking results identified gingerol as exhibiting the highest binding affinity for elastase (-7.99 kcal/mol), followed by carvacrol (-6.79 kcal/mol) and ferulic acid (-6.24 kcal/mol). Similarly, for collagenase, gingerol displayed the strongest interaction (-8.47 kcal/mol), followed by carvacrol (-6.30 kcal/mol) and α-pinene (-6.24 kcal/mol). Notably, gingerol and carvacrol also demonstrated favorable amino acid similarity scores and promising interactions within the active sites of both elastase and collagenase. In conclusion, this molecular docking study suggests that the secondary metabolites of I. verum fruit possess potential anti-aging activity by inhibiting elastase and collagenase enzymes.
Co-Authors Anang Setyo Wiyono Bambang Tri Purwanto Esti Hendradi Hariyadi, Dewi Melany Ida Kristianingsih Juni Ekowati Maulia, Arwinda Ninis Yuliati, Ninis Purnomo, Ahmad Toto Ramadhani, Firmansyah Ardian Retno Widyowati Savitri, Orchidea Meidy Nurintan Siswandono, Siswandono Tri Widiandani Yusuf, Helmy