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ANTIDIABETIC POTENTIAL OF SOLID LIPID NANOPARTICLES (SLNS) FROM KABAU SEED (ARCHIDENDRON BUBALINUM (JACK) I.C. NIELSEN) EXTRACT COATED WITH TRIMYRISTIN Balqis, Solina; Diah Miftahul Aini; Muhammad Arif Fadilah; Nurkayah; Mu'awiyatu Al-Laitsi; Lia Aseptin Murdini; Elva Febriyanti
ALOTROP Vol. 9 No. 1 (2025): Jurnal Pendidikan dan Ilmu Kimia
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/alo.v9i1.42075

Abstract

Type 2 diabetes mellitus is a global health problem that continues to increase. One alternative approach in managing diabetes is using natural materials with antihyperglycemic activity. This study aims to evaluate the effectiveness of solid lipid nanoparticles (SLN) containing Kabau seed extract (Archidendron bubalinum (Jack) I.C. Nielsen) coated with trimyristin in reducing blood glucose levels in hyperglycemic rats. Extraction was carried out by maceration using 96% ethanol, while SLN was synthesized by high-speed homogenization and ultrasonication methods. Particle size analysis showed an average diameter of 262.61 nm with a polydispersity index (PDI) of 0.144, indicating a homogeneous formulation. Phytochemical testing showed that Kabau seed extract contains alkaloids, flavonoids, tannins, and saponins contributing to antihyperglycemic activity. In vivo tests on Mus musculus showed that 20 % concentration of Kabau SLN reduced blood glucose levels by up to 97 mg/dL, approaching the effectiveness of metformin (104 mg/dL). Statistical analysis of ANOVA and BNT test showed significant differences between treatments. These results indicate that Kabau SLN has the potential as a candidate for phytopharmaceuticals in managing type 2 diabetes mellitus. Keywords: Diabetes mellitus; Kabau; solid lipid nanoparticles; trimyristin; flavonoids
Formulasi Busa dari Lateks Cair (Hevea brasiliensis) Asal Kabupaten Musi Rawas Aseptin Murdini, Lia; Nurkayah; Syaifudin
Konservasi Hayati Vol 21 No 2 (2025): OKTOBER
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/hayati.v21i2.45004

Abstract

Musi Rawas is one of the major rubber plantations (Hevea brasiliensis) in South Sumatra. However, prolonged fluctuations and the decline in natural rubber prices have contributed to reduced household income among rubber farmers, affecting their economic stability. This situation highlights the need to enhance the added value of natural rubber products as a strategy to improve farmer welfare and support the achievement of Sustainable Development Goal (SDGs) 1, which aims to alleviate poverty. One promising approach is the utilization of natural rubber latex for foam production through formulation optimization, particularly by adjusting the concentration of zinc-mercaptobenzothiazole (ZMBT), a secondary accelerator known to influence physical properties. This study aimed to evaluate the effect of ZMBT concentrations on the physical properties of natural rubber latex foam. The research was conducted from February to June 2025 at the Integrated Laboratory, Institut Teknologi Muhammadiyah Sumatera, utilizing natural rubber latex sourced from local farmers in Musi Rawas. Three ZMBT concentrations were tested, namely 0.5 phr (A), 1.0 phr (B), and 2.0 phr (C), while all other formulation ingredients were kept constant. The physical properties evaluated included Compression Set (ASTM D395-16e1), Hardness Shore A, Tensile Strength, and Elongation at Break (ASTM D412-16). Based on the results of the research and analysis conducted, it can be concluded that the optimal concentration of ZMBT is at 1 phr, exhibiting physical characteristics including a Compression Set of 86.29%, a Hardness Shore A of 60.05 E.S., a Tensile Strength of 0.1 MPa, and an Elongation at Break of 370%.
Multi-Stakeholder Collaboration in Liquid Organic Fertilizer Production Training for Community Empowerment in Sukakarya Village: Pengabdian Solina Balqis; Nurkayah; Rafikha Anggraini; Nadia Ulfa; Dayu Kristianto; Anggun Febiana; M. Agustian Alfarizi; Dwi Tusmila8; Malyan Khasanah Isnaini; Rohmadi
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 4 No. 3 (2026): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 4 Nomor 3 (Januari 202
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v4i3.4349

Abstract

This community service program aimed to enhance community capacity in managing household organic waste through training on liquid organic fertilizer (LOF) production in Sukakarya Village. The program was implemented using a multi-stakeholder collaboration involving university lecturers, an industrial partner (Pertamina), and the local women farmer group (KWT Melati). The activity adopted a participatory approach combining educational sessions, hands-on training, and evaluation through pre- and post-tests. Household organic waste such as vegetable residues, fruit peels, and leftover rice was processed using a simple anaerobic fermentation method with Effective Microorganisms 4 (EM4) as a bioactivator. The results showed a significant improvement in participants understanding of waste management, circular economy concepts, and LOF production procedures. In addition, participants demonstrated increased environmental awareness and readiness to independently produce LOF at the household level. Although the program was limited to the production stage without field application, the outcomes indicate strong potential for sustainable waste management and community empowerment. This initiative highlights the effectiveness of community-based education supported by multi-stakeholder collaboration as a replicable model for rural environmental sustainability programs.
Empowering Junior High School Students through Eco-Enzyme Production Training from Fruit Peel Waste: A Community Engagement Program at SMPIT Al-Qudwah, Tugumulyo District: Penelitian Solina Balqis; Elva Febriyanti; Nurkayah; Muhammad Arif Fadillah; Lia Aseptin Murdini; Aldi Fahlefi; Hosiaroba; Viar Refri Zadin
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 4 No. 3 (2026): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 4 Nomor 3 (Januari 202
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v4i3.4350

Abstract

Organic waste management, particularly fruit peel waste, remains a challenge in school environments. Eco-enzyme production offers a simple and environmentally friendly solution that also supports environmental education. This community service program aimed to improve students’ knowledge and skills in managing fruit peel waste through eco-enzyme production training at SMPIT Al-Qudwah. The program was implemented using a hands-on training approach, including material delivery, direct practice, and evaluation using a pretest–posttest design involving 15 students. The results showed a clear increase in posttest scores compared to pretest scores, indicating improved understanding of organic waste management and eco-enzyme production. The training effectively enhanced students’ environmental awareness and practical skills, demonstrating the potential of experiential learning as a replicable model for school-based environmental education