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All Journal Midwinerslion : Jurnal Kesehatan STIKes Buleleng Cakrawala Medika: Journal of Health Sciences
Cindy Junita Romli
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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UJI ANTIOKSIDAN PADA EKSTRAK ETANOL RIMPANG KUNYIT (CURCUMA LONGA L.) MENGGUNAKAN METODE DPPH (2,2-DIFENIL-1-PIKRILHIDRAZIL) Muhammad Anwar, La Ode; Cindy Junita Romli
Cakrawala Medika: Journal of Health Sciences Vol. 3 No. 1 (2024): Cakrawala Medika: Journal of Health Sciences
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Medika Suherman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59981/vt055345

Abstract

Kunyit (Curcuma longa L.), sebagai tanaman obat tropis dari famili Zingiberaceae, memiliki potensi antioksidan yang tinggi melalui kandungan kurkumin dan turunannya. Aktivitas antioksidan ini berperan penting dalam melindungi tubuh dari radikal bebas, sehingga menarik perhatian dalam penelitian fitoterapi. Penelitian ini bertujuan untuk mengevaluasi aktivitas antioksidan ekstrak kunyit menggunakan metode DPPH. Ekstrak etanol kunyit dengan konsentrasi 10, 15, dan 20 ppm dimana setiap seri konsentrasi diteteskan larutan DPPH sebanyak 1 mL. Setiap konsentrasi ekstrak diukur pada panjang gelombang 517 nm menggunakan alat spektrofotometri UV-Vis. Analiisi data menggunakan regresi linear untuk mendapatkan nilai IC50. Hasil menunjukkan bahwa ekstrak kunyit memiliki nilai IC50 sebesar 3,203 µg/mL, yang dikategorikan sebagai aktivitas antioksidan sangat kuat (IC50 <50 µg/mL). Aktivitas antioksidan menunjukkan hubungan positif dengan peningkatan konsentrasi ekstrak. Ekstrak kunyit memiliki potensi antioksidan yang sangat kuat, mendukung penggunaannya sebagai agen antioksidan alami.
PEMBERIAN SALEP EKSTRAK DAUN PISANG AMBON (Musa paradisiaca var.sapientum) TERHADAP ULKUS TIKUS DIABETIK YANG DIINDUKSI ALOKSAN: Array La Ode Muhammad Anwar; Armi Armi; Marselina Marselina; Masita Sari Dewi; Salma Hilmy Rusydi Hashim; Embriana Dinar Pramestyani; Nuzul Gyanata Adiwisastra; Cyto Yudha Kurniawan; Cindy Junita Romli; Awanda Pramudita Okhanza; Mahesa Mahesa
Midwinerslion : Jurnal Kesehatan STIKes Buleleng Vol 9 No 2 (2024): MIDWINERSLION Jurnal Kesehatan STIKes Buleleng
Publisher : LPPM STIKes Buleleng

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52073/mjksb.v9i2.382

Abstract

Introduction: Diabetes is a chronic condition that occurs when the pancreas does not produce enough insulin or when the body cannot adequately use the insulin it does produce. This increases the sugar in the blood. One of the effects of diabetes is the formation of ulcers. Method: The ointment preparation formulations that have been made are then evaluated, including organoleptics, homogeneity, spreadability, pH, viscosity, and stability. The test animals used were 30 test animals consisting of 5 groups, each group consisting of 5 rats. Group I rats were given a topical preparation of 10% extract ointment. Group II was given a topical preparation of ointment extract with a concentration of 15%. Group III topical preparation of ointment extract with a concentration of 20% Group IV without treatment. Group V, as a positive control, was given betadine ointment. Induction of rats was done by giving alloxan monohydrate intraperitoneally. Results: Ulcer testing on 10% ointment has the best healing rate compared to the control. The 20% ointment took four days to heal the ulcer. The 15% ointment and the control took six days to heal. Conclusion: The 10% ointment formula has the best healing of diabetic ulcers compared to the control given.
Co-Authors Armi Armi Awanda Pramudita Okhanza Cyto Yudha Kurniawan Embriana Dinar Pramestyani La Ode Muhammad Anwar La Ode Muhammad Anwar Mahesa Mahesa Marselina Marselina Masita Sari Dewi Nuzul Gyanata Adiwisastra Salma Hilmy Rusydi Hashim