Article Per Year (5 Year)
p-Index From 2020 - 2025
1.204
P-Index
This Author published in this journals
All Journal Jurnal Biologi Tropis Jurnal Kesehatan Tambusai
Yuar, Alana Akmal
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 8 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 8 Documents
Search

 1 
Hypothyroidism with Myxedema Coma Complications: A Review of Articles during November 2024 Paramadinda, Ni Made Ayu Mas Sista; Aulia, Siti Zahroni; Rahmawati, Fadila; Yuar, Alana Akmal; Valencia, Perlin Nigel; Qadri, Annisa Salsabila; Rabbani, Yaskuna Urfi; Hakim, Baiq Sheila Oktalia; Yolanda, Rizki; Wibawa, Galang Edi
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.9984

Abstract

Hypothyroidism is a condition characterized by decreased thyroid hormone production due to impaired thyroid or hypothalamic-pituitary gland function. Hypothyroidism is more common in women due to iodine deficiency. This condition can also be caused by autoimmune disorders. Symptoms of hypothyroidism vary, from mild, with few or no symptoms, to severe. Most symptoms are variable, vague, and delayed in onset. This paper aims to provide a comprehensive understanding of the diagnosis and management of hypothyroidism complicated by myxedema coma. The writing method used in this literature review is references from various Indonesian and English-language literature. The literature search was conducted during November 2024, with 10 articles obtained. The review results showed that severe and uncontrolled hypothyroidism can lead to myxedema coma. Myxedema coma is a condition characterized by decreased consciousness accompanied by generalized edema. This condition frequently associated with hypothermia and hyponatremia. Myxedema coma can be diagnosed using a scoring system. Therefore, an understanding of how to diagnose and properly manage hypothyroidism with complications of myxedema coma is needed for early detection so as not to worsen the patient's prognosis.
Diagnosis and Management of Cholangiocarcinoma (CCA) Hakim, Baiq Sheila Okthalia; Rahmawati, Fadila; Yuar, Alana Akmal; Setiasari, Febi Jian; Evana, Nafisya Ayu; Yolanda B.S, Moh Rizky
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10162

Abstract

Cholangiocarcinoma (CCA) is a malignant tumor of the biliary epithelium and represents the second most common primary liver cancer after hepatocellular carcinoma. Its incidence and mortality rates are particularly high in Asia. This review aims to provide an updated overview of risk factors, pathogenesis, diagnostic strategies, and current management of cholangiocarcinoma based on recent scientific evidence from the past decade. A narrative literature review was conducted using publications retrieved from PubMed, Scopus, and Google Scholar, limited to the last 10 years. Eligible studies included original research, systematic reviews, clinical trials, and international clinical practice guidelines addressing epidemiology, biomarkers, imaging modalities, molecular testing, as well as surgical and non-surgical treatment options. CCA is classified into intrahepatic (iCCA) and extrahepatic (eCCA: perihilar and distal). Risk factors include parasitic infections, congenital biliary anomalies, cirrhosis, viral hepatitis, and toxin exposure. Management depends on resectability: surgical resection with adjuvant capecitabine provides curative benefit, while advanced disease requires systemic chemotherapy (gemcitabine–cisplatin), second-line FOLFOX, and palliative interventions such as biliary stenting and drainage. Early detection in high-risk populations is essential to improve diagnostic accuracy and treatment outcomes. A multimodal strategy combining biomarkers, imaging, and molecular analysis enhances early recognition and guides therapy. Routine screening programs, development of novel biomarkers, and further studies on targeted therapies and immunotherapy are recommended to broaden future treatment options.
Literature Study: Primary Immunodeficiency Rahmadinna, Sandia Anggun; Yuar, Alana Akmal; Musyafa, Aulia Putri; Hardiant, Excell Defry; Putri, Baiq Ghefira Rojwani; Muliana, Atriska Citra; Salsabila, Septy Rianty Putri; Ningrum, Sania Tresna; Narendra, Ahmad Wahyu; Ramadhania, Yasmine Najla; Habib, Philip
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10168

Abstract

Abnormalities in immune system development and function result in increased susceptibility to infection and reactivation of latent infections. Other immunodeficiencies can result in mild infections and may first be detected in adulthood. This literature review aims to discuss primary immunodeficiencies, including their definition, causes, treatment, and examples of the diseases they cause. This literature review was compiled through a literature search method by reviewing various scientific journals obtained from databases such as PubMed, Google Scholar, and ScienceDirect. The results Primary immunodeficiency disease (PID) results from immune system defects caused by mutations in the genetic code that codes for components of the body's immune system. PID is broadly classified as either a disorder of adaptive immunity (T-cell, B-cell, or combined immune deficiencies) or innate immunity (phagocyte and complement deficiencies). Patients with PID may experience a variety of lung problems, including recurrent lower respiratory tract infections, lung parenchymal abnormalities, asthma, ventilation abnormalities, and bronchiectasis (BE). In conclusion, primary immunodeficiency disease (PID) refers to a large, heterogeneous group of disorders characterized by abnormalities in the development and/or function of the immune system. These conditions result from immune system defects caused by mutations in the genetic code that codes for components of the body's immune system.
Brain Arteriovenous Malformations: Diagnostic Challenges and Therapeutic Options Maurae, Perlin Nigel Valencia; Hakim, Baiq Sheila Oktalia; Yuar, Alana Akmal
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10205

Abstract

AVMs involve complex hemodynamic disturbances, including vascular steal and venous hypertension, as well as molecular underpinnings such as mutations in the KRAS, ENG, or ALK1 genes that trigger dysregulation of angiogenesis and endothelial-mesenchymal transition (EndMT). This literature review aims to comprehensively analyze the pathophysiological aspects, diagnosis, and current therapies for brain AVMs, including the development of targeted therapies such as MEK inhibitors and anti-VEGF, as well as their clinical implications in reducing bleeding risk and improving patient outcomes. This literature review was conducted using a systematic literature review method through searching scientific articles and references related to brain arteriovenous malformations (AVMs). The results of the literature study show that brain arteriovenous malformations (AVMs) are congenital vascular abnormalities characterized by abnormal connections. With an incidence of 1.34 per 100,000 person-years, AVMs are often asymptomatic until complications arise, with bleeding being the primary presentation in 50% of cases. Diagnosis requires multimodal imaging (CT/MRI/DSA) and the Spetzler-Martin classification to assess therapeutic risk. Treatment includes a multimodal approach: microsurgery (effective for small, non-eloquent AVMs), radiosurgery (staged obliteration with risk of edema), and embolization (as adjuvant therapy). The discovery of genetic mutations (KRAS, ENG) and dysregulation of signaling pathways (TGF-β/VEGF) opens the door to targeted therapies such as MEK inhibitors or anti-VEGF. Multidisciplinary collaboration and an understanding of the molecular pathophysiology are key to improving patient outcomes. In conclusion, brain AVMs represent a complex clinical challenge that requires an integrated understanding of pathophysiology, accurate diagnosis, and risk-based therapeutic strategies.
Effectiveness of Sunscreen in Preventing Skin Problems Wibawa, Galang Edi; Yuar, Alana Akmal; Rahmawati, Fadila; Maurae, Perlin Nigel Valencia; Hakim, Baiq Sheila Oktalia; Bisa, Muhammad Rizky Yolanda; Paramadinda, Ni Made Ayu Mas Sista; Aulia, Siti Zahroni; Rabbani, Yaskuna Urfi
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10301

Abstract

Sunlight contains ultraviolet (UV) radiation, which is part of the electromagnetic spectrum. Low awareness of the importance of skin protection, as well as the perception that sunscreen use is incompatible with masculine image, is due to a lack of education. This paper aims to discuss the importance of sunscreen use as a preventive measure in maintaining skin health, especially in areas with high UV exposure such as NTB. The results of a literature study found that ultraviolet light is part of the electromagnetic spectrum originating from the sun. UVA, UVB, and UVC rays are the three types of these rays that may be distinguished by their wavelength. One of the major risk factors for developing skin cancer is exposure to UVA and UVB radiation. Sunscreen is one way to chemically protect the skin from the sun. Active ingredients in sunscreen have the ability to absorb, disperse, and reflect sunlight to provide the best possible protection for the skin. The chemical structure known as aromatic molecules conjugated with carbonyl groups is the mechanism of action of chemical sunscreens. The degree of hyperpigmentation is greatly impacted by proper sunscreen use. In conclusion, the public should be taught about the importance of wearing sunscreen in order to avoid the acute and long-term consequences of excessive UV exposure.
TINJAUAN PUSTAKA TERBARU SKELETAL TRAKSI : INDIKASI, TEKNIK, DAN PERANNYA DALAM PENANGANAN FRAKTUR Rabbani, Yaskuna Urfi; Qadri, Annisa Salsabila; Yuar, Alana Akmal; Rahmawati, Fadila; Wibawa, Galang Edi; Maurae, Perlin Nigel Valencia; Hakim, Baiq Sheila Oktalia; Surya, Muhammad Rizky Yolanda Biman; Paramadinda, Ni Made Ayu Mas Sista; Aulia, Siti Zahroni
Jurnal Kesehatan Tambusai Vol. 6 No. 3 (2025): SEPTEMBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i3.49184

Abstract

Fraktur merupakan kondisi medis akibat patahnya tulang akibat trauma seperti kecelakaan lalu lintas, jatuh, atau cedera olahraga. Indonesia termasuk negara dengan jumlah kasus fraktur tertinggi di Asia Tenggara. Penanganan fraktur yang tidak tepat dapat menimbulkan komplikasi serius. Salah satu metode tatalaksana definitif yang digunakan adalah traksi skeletal, yakni teknik invasif yang menggunakan pin yang ditanamkan langsung ke tulang untuk menciptakan gaya tarik yang stabil. Tulisan ini bertujuan memberikan pemahaman menyeluruh mengenai indikasi, teknik, dan peran traksi skeletal dalam manajemen fraktur. Metode penulisan berbentuk tinjauan pustaka berdasarkan artikel jurnal nasional dan internasional yang relevan. Hasil pembahasan menunjukkan bahwa skeletal traksi memiliki banyak manfaat seperti stabilisasi fraktur, mengurangi nyeri akibat spasme otot, hingga memfasilitasi tindakan pembedahan lebih lanjut. Tindakan ini memerlukan teknik yang tepat dan perawatan khusus untuk mencegah komplikasi seperti infeksi dan kerusakan neurovaskular. Oleh karena itu, pemahaman terhadap teknik pemasangan, indikasi, kontraindikasi, dan pelepasan sangat penting untuk meningkatkan hasil klinis pasien dengan fraktur.
Comprehensive Review of Antihypertensive Therapy: Pathophysiology, Diagnosis, and Management Yuar, Alana Akmal
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10470

Abstract

Hypertension is fundamentally defined as a medical condition characterized by persistent elevations in systemic blood pressure. Various approaches to address hypertension include pharmacological and non-pharmacological therapies. This literature review aims to comprehensively review antihypertensive therapy: pathophysiology, diagnosis, and management. This article was compiled using a literature review method and developed using the PRISMA approach. The findings indicate that hypertension therapy can be carried out in two ways: pharmacological and non-pharmacological. Non-pharmacological therapy through lifestyle interventions is not only effective in lowering blood pressure but also provides overall health benefits. The main components of non-pharmacological interventions include dietary modification, physical activity, weight management, and cessation of detrimental habits such as smoking and excessive alcohol consumption. Pharmacological therapy is based on two main factors: blood pressure levels and the patient's total cardiovascular risk profile. Modern treatment strategies strongly recommend the use of combination therapy as an initial step in most patients. The recommended combination is a renin-angiotensin system (RAS) blocker (ACE inhibitor or ARB) with a calcium channel blocker (CCB) or a diuretic. A new and emerging pharmacological approach is more comprehensive RAAS inhibition. In conclusion, hypertension therapy can be carried out in 2 ways, namely non-pharmacological therapy and pharmacological therapy.
Pseudocyesis: From Psycho-Social Conflict to Somatic Reality, A Literature Review Athalia, Ihza Namira; Yuar, Alana Akmal
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10539

Abstract

Pseudocyesis or pseudopregnancy is a psychosomatic condition that can occur in certain extreme situations when mental anguish, neuroendocrine malfunction, and social stress intersect. Pseudocyesis is often associated with affective disorders such as major depressive disorder, which can modulate the activity of the hypothalamic-pituitary-ovarian axis. This literature review aims to comprehensively discuss the basic concept of pseudocyesis, its etiology and pathophysiology, its relationship to depression and socio-cultural factors, and highlight the importance of a multidisciplinary approach to diagnosis and management in understanding this phenomenon as a complex biopsychosocial disorder. This article was written using the Literature Review method and compiled with the PRISMA approach. Pseudocyesis is still reported to be quite common in developing countries, particularly in rural communities in Africa and Asia. Pseudocyesis occurs due to several factors, including psychological and hormonal, as well as social and cultural factors. The pathophysiology of pseudocyesis lies in dysregulation of the Hypothalamic-Pituitary-Ovarian (HPO) axis, which is the primary control system for the female reproductive cycle. Women with pseudocyesis exhibit an endocrine profile that shares many similarities with Polycystic Ovarian Syndrome (PCOS) and Major Depressive Disorder. The most commonly reported symptoms include menstrual disorders such as amenorrhea (cessation of menstruation) or oligomenorrhea (irregular menstrual cycles), morning sickness, vomiting, and weight gain. Pseudocyesis can be managed through a combination of supportive psychotherapy, cognitive-behavioral therapy (CBT), and psychoanalytic therapy. Furthermore, family involvement, especially the partner, in the therapy process plays a vital role.
Co-Authors Athalia, Ihza Namira Aulia, Siti Zahroni Bisa, Muhammad Rizky Yolanda Evana, Nafisya Ayu Habib, Philip Hakim, Baiq Sheila Oktalia Hakim, Baiq Sheila Okthalia Hardiant, Excell Defry Maurae, Perlin Nigel Valencia Muliana, Atriska Citra Musyafa, Aulia Putri Narendra, Ahmad Wahyu Ningrum, Sania Tresna Paramadinda, Ni Made Ayu Mas Sista Putri, Baiq Ghefira Rojwani Qadri, Annisa Salsabila Rabbani, Yaskuna Urfi Rahmadinna, Sandia Anggun Rahmawati, Fadila Ramadhania, Yasmine Najla Salsabila, Septy Rianty Putri Setiasari, Febi Jian Surya, Muhammad Rizky Yolanda Biman Valencia, Perlin Nigel Wibawa, Galang Edi Yolanda B.S, Moh Rizky Yolanda, Rizki