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Khotimah, Andi Husnul
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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A Literature Review: Acute Tonsillitis Azzahra, Anis Aura; Khotimah, Andi Husnul; Sugiono, Muhammad Rafly Adrian; Zulkifli, Yasmin Sabrina
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10202

Abstract

Acute tonsillitis is a bacterial infection characterized by painful swallowing, swelling, and redness of the tonsils. The purpose of this literature review is to improve understanding of acute tonsillitis, which is essential for patient care and a favorable prognosis. The method used is a systematic literature review. The results of this literature review indicate that tonsillitis is a common inflammatory condition affecting the palatine tonsils, accounting for approximately 1.3% of outpatient visits. The condition is typically caused by viral or bacterial infections and manifests with symptoms such as sore throat, fever, odynophagia, and tonsillar erythema or exudate. Viral tonsillitis is often self-limiting; however, bacterial causes most notably Streptococcus group A can lead to significant complications, including peritonsillar abscess, acute rheumatic fever, and poststreptococcal glomerulonephritis. Prompt and accurate diagnosis is essential to distinguish viral from bacterial etiologies. Clinical scoring systems, such as the Centor or McIsaac criteria, and microbiological testing, help guide appropriate management and reduce unnecessary antibiotic use. Early identification and intervention are critical to preventing complications and promoting effective recovery. In conclusion, the prognosis for acute tonsillitis is generally good, with most cases healing on their own without complications.
Cerebral Palsy: Risk Factors, Pathophysiology, Clinical Manifestations, Diagnosis, and Management Damayanti, Ida Ayu Andara; Prawira, I Nyoman Dio Yudha; Andini, Syabila; Hanifah, Hanum Retno; Wiguna, I Made Danuarta; Wulandari, Baiq Nurhandini; Sabrina, Khansa Aulia; Khotimah, Andi Husnul; Wardana, Shira Putri; Rizqullah, Rifqi; Haikal, Muhammad
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10564

Abstract

Cerebral palsy is a non-progressive neuromotor disorder and the leading cause of motor disability in children worldwide, particularly in low- and middle-income countries. This study aims to examine the risk factors, pathophysiology, clinical manifestations, diagnosis, and management of cerebral palsy based on recent scientific literature. This article includes a systematic literature review using the PRISMA method and selected 15 articles that met the inclusion and exclusion criteria. The results of the systematic literature review were obtained risk factors for cerebral palsy include intrauterine infection, preeclampsia, premature birth, asphyxia, and hypoxic-ischemic encephalopathy and hyperbilirubinemia. These risk factors can disrupt neurogenesis and brain maturation, leading to structural and functional damage to the central nervous system. Clinical manifestations of cerebral palsy include impaired muscle tone, abnormal reflexes, and postural deformities, classified as spastic, dyskinetic, and ataxic, and assessed using the Gross Motor Function Classification System (GMFCS). The diagnosis of cerebral palsy is established through evaluation of the clinical history, neurological/motor examination, neuroimaging, and genetic testing. Cerebral palsy management aims to improve functionality, ability, and health in movement, cognition, social interaction, and independence. Non-pharmacological management focuses on physiotherapy and occupational therapy to improve motor skills, reduce spasticity, and support independence. The mainstay of pharmacotherapy in cerebral palsy management uses systemic medications that are symptom-based and directed at specific movement disorders.
Co-Authors Andini, Syabila Azzahra, Anis Aura Damayanti, Ida Ayu Andara Hanifah, Hanum Retno Muhammad Haikal Prawira, I Nyoman Dio Yudha Rizqullah, Rifqi Sabrina, Khansa Aulia Sugiono, Muhammad Rafly Adrian Wardana, Shira Putri Wiguna, I Made Danuarta Wulandari, Baiq Nurhandini Zulkifli, Yasmin Sabrina