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All Journal Jurnal Ilmiah Kedokteran Wijaya Kusuma Oto Rhino Laryngologica Indonesiana MAHESA : Malahayati Health Student Journal Hang Tuah Medical Journal Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Holistik Jurnal Kesehatan
LINGGAWAN, STEPHANI
Fakultas Kedokteran Universitas Wijaya Kusuma Surabaya
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Membranous Tonsilitis as a Clinical Presentation of Acute Monocytic Leukemia: A Rare Case Report Linggawan, Stephani; Wibowo, Eric Satrio Adi; Gunawan, Catherine Keiko; Raharjo, Budiono; Sumarpo, Anton; Raharjo, Yohanes Timothy; Dwijayanti, Ni Made Intan; Yudho Bintoro, Siprianus Ugroseno
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol. 14 No. 2 (2025): SEPTEMBER 2025
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v14i2.4290

Abstract

Background: Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by the clonal proliferation of immature myeloid precursor cells in the bone marrow and peripheral circulation. Hematologic manifestations such as anemia, thrombocytopenia, and leukocytosis are welldocumented, its association with oral involvement, particularly tonsillitis, is a rare presenting feature. Objective: This case report emphasizes membranous tonsilitis as the primary presenting feature in acute monocytic leukemia (AML-M5). The aim of writing this case study is to provide an illustration that the causes of membranous tonsillitis, beside from the infection, can also be caused by infiltration of leukemia cells. Case Presentation: We report a case of a 27-year-old female presented with fever and was found to have a fluctuating mass on the right side of the neck along with gingival swelling and hyperemic, hypertrophic tonsils with a membranous exudate. The diagnosis from bone marrow aspiration and immunophenotyping revealed as acute monocytic leukemia (AML-M5). Bacterial and fungal infections were excluded through gram staining, potassium hydroxide (KOH) examination, and throat swab culture. The patient was initially stabilized with hydroxyurea, with subsequent clinical improvement, before being referred to a tertiary center for definitive management. Result: This diagnostic workup altogether from all the clinicians leads to the diagnosis of acute myeloid leukemia (AML-M5). Conclusion: This case highlights primary tonsilitis as the primary presenting feature of acute myeloid leukemia (AML-M5), emphasizing the need for continued monitoring and regular follow-up assessment to detect potential relapses and ensure optimal disease management
Hubungan Antara Kepatuhan Kontrol dan Minum Obat Pasien Diabates Melitus Tipe II dengan Kejadian Komplikasi di Rumah Sakit Aura Syifa Kediri Jordanio Viari Palallo; Febtarini Rahmawati; Stephani Linggawan
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 5 No. 2 (2026): Agustus: Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v5i2.9845

Abstract

Type 2 diabetes mellitus is a chronic disease characterized by impaired glucose metabolism resulting from insulin resistance or relative insulin deficiency. It is one of the major global health problems and can lead to various serious complications if not managed properly. Complications such as neuropathy, nephropathy, retinopathy, and diabetic ulcers frequently occur as a consequence of inadequate blood glucose control, which is strongly influenced by patients' adherence to medication and routine follow-up visits. This study aimed to determine the relationship between medication adherence, follow-up adherence, and the occurrence of complications among patients with type 2 diabetes mellitus at Aura Syifa Hospital, Kediri. This study employed an analytical observational design with a cross-sectional approach. A total of 35 patients were selected using purposive sampling. Data were collected from medical records and analyzed using Fisher's Exact Test. The results revealed a significant relationship between medication adherence and the occurrence of complications (p < 0.002), as well as between follow-up adherence and complications (p = 0.027). These findings indicate that patients who are non-adherent to medication and routine follow-up are at a higher risk of developing complications. Therefore, strengthening patient education, supervision, and adherence monitoring systems is essential in healthcare services to prevent disease progression and reduce the incidence of complications. This study is expected to serve as a basis for developing educational interventions and primary healthcare policies aimed at improving the management of patients with type 2 diabetes mellitus.
Co-Authors Agus Kurniawan Agus Kurniawan Anggono, Susan Jocelyn Anton Sumarpo Bintoro, Siprianus Ugroseno Yudho Catherine Keiko Gunawan Damayanti, Inggit Dewi, Ni Luh Arisda Satya Cahya Dwijayanti, Ni Made Intan Edi Handoko Efawati, Susi Endang Retnoningsih Eric Satrio Adi Prabowo Febtarini Rahmawati Febtarini Rahmawati Fitrianto, Muhammad Rizki Gunawan, Catherine Keiko Herawaty, Wike Hernanda, PratikaYuhyi Heru Setiawan Jordanio Viari Palallo Kurniawati, Renny Nastietie, Arinda Rindang Ngibad, Khoirul Prabowo, Eric Satrio Adi RAHARJO, BUDIONO Raharjo, Yohanes Timothy Rus Suheryanto Soehartono Soehartono Sugeng, Maria Widjianti Tjokro, Vanessa Susanto Wibowo, Eric Satrio Adi Wijayanti, Christina Destri Wiwis Yudho Bintoro, Siprianus Ugroseno