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All Journal MEDISAINS KOVALEN: Jurnal Riset Kimia CHEMPUBLISH JOURNAL Lantanida Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) As-syifaa Jurnal Farmasi Pharmasipha Jurnal Farmasi Higea Health Sciences and Pharmacy Journal INTEGRITAS : Jurnal Pengabdian Jurnal ABDINUS : Jurnal Pengabdian Nusantara Jurnal Inovasi Farmasi Indonesia Medicra (Journal of Medical Laboratory Science/Technology) Prosiding Conference on Research and Community Services MAHESA : Malahayati Health Student Journal Environmental and Toxicology Management (ETM) CHEDS: Journal of Chemistry, Education, and Science Jurnal Pengabdian Sosial Lestari: Jurnal Pengabdian Kepada Masyarakat JI-KES (Jurnal Ilmu Kesehatan)
Ngibad, Khoirul
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UJI FITOKIMIA DAN AKTIVITAS ANTIOKSIDAN EKSTRAK METANOL DAUN ZODIA (EVODIA SUAVEOLENS) Ngibad, Khoirul; Lestari, Lilla Puji
Jurnal Ilmiah As-Syifaa Vol 11, No 2 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (294.973 KB)

Abstract

Zodia (Evodia suaveolens) plant is commonly used by the community to repel mosquitoes. The plant is native to Papua but has been widely cultivated in Java such as: Batu, Depok, Bogor, Bandung and Surabaya. The aim of this study is to determine the antioxidant activity of zodia leaves methanol extract. In addition, to determine the class of secondary metabolites of the methanol extract of zodia leaves. The extraction process was carried out by maceration method using methanol solvent for 3 days then the filtrate was concentrated using a rotary evaporator. The antioxidant potential of zodia leaves methanol extract was tested using the DPPH method (1,1-Diphenyl-2-picrylhydrazyl) with a UV-Vis spectrophotometer while the determination of secondary metabolite compounds from zodia leaves methanol extract was carried out qualitatively using reagents. The results of the phytochemical test showed that the methanol extract of zodia plant leaves contained group of alkaloid, flavonoids, and tannins compounds while the antioxidant activity test of zodia methanol extract using the DPPH method were shown with an IC50 value of 55,69 ppm while These results indicated that the zodia leaves methanol extracts have strong category of antioxidant activity.
PENYULUHAN HIGIENE DAN SANITASI PADA UMKM SIRUP MARKISA DI DESA JATIKALANG SIDOARJO Ngibad, Khoirul; Sungging Pradana, Muhammad
Prosiding Conference on Research and Community Services Vol 2, No 1 (2020): Second Prosiding Conference on Research and Community Services
Publisher : STKIP PGRI Jombang

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Abstract

Buah markisa menjadi salah satu bahan untuk membuat minuman kesehatan. Biasanya masyarakat lebih menyukai konsumsi buah markisa dalam bentuk sirup.Dalam program PKM (Program Kemitraan Masyarakat) ini, yang kami pilih adalah 1 mitra usaha yang bergerak dalam pembuatan sirup markisa di Dusun Jatisari Desa Jatikalang Kecamatan Krian Kabupaten Sidoarjo. Salah satu permasalahan mitra dalam dalam aspek produksi adalah mitra PKM melupakan aspek higienitas dalam proses pembuatan sirup markisa. Oleh karena itu, tim pengabdian masyarakat akan memberikan penyuluhan tentang higiene dan sanitasi. Metode yang digunakan dalam pengabdian masyarakat ini adalah metode ceramah dan diskusi tentang higiene dan sanitasi. Kemudian, di akhir penyuluhan tim pengabdian masyarakat melakukan evaluasi dengan cara memberikan kuisioner tingkat pengetahuan personal higiene karyawan. Penyuluan tentang higiene dan sanitasi dengan mitra UMKM yang bergerak dalam pembuatan sirup markisa dapat diselenggarakan dengan lancar. Selain itu, penyuluhan higiene dan sanitasi dapat memberikan peningkatan pengetahuan dan ketrampilan SDM mitra.
Aktivitas Antioksidan Kombinasi Ekstrak Etanol 96 % Kulit Buah Markisa Ungu dan Kuning secara In-Vitro Fitria, Laila; Ngibad, Khoirul
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol. 6 No. 2 (2022): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v6i2.8682

Abstract

This study aimed to find the best combination of 96% ethanol extract from purple passion fruit (Passiflora edulis f. edulis Sims) peel and yellow passion fruit (Passiflora edulis Sims f. flavicarpa Deg) peel as in vitro antioxidants using the DPPH method. The 96% ethanol extract of purple and yellow passion fruit peel was obtained by the maceration method using 96% ethanol solvent. The combination treatment of purple and yellow passion fruit peel extracts was made with three comparisons of namely 1:1, 2:1, and 1:2, respectively. In vitro, antioxidant activity was assayed using the DPPH method to obtain the IC50 value. The results showed that the best combination of extracts as in vitro antioxidants was the combination of 96% ethanol extract from purple and yellow passion fruit peel with ratio (1:1) of 12.45 mg/L followed by the combination of extracts 1:2 (51.31 mg/L) and 2:1 (66.23 mg/L). In conclusion, the results suggest that the extracts combination of purple and yellow passion fruit peel with a ratio (1:1) can increase in vitro antioxidant activity.
Penentuan Konsentrasi Ammonium dalam Air Sungai Pelayaran Ngelom: Determination of Ammonium Concentration in Ngelom . Shipping River Water Ngibad, Khoirul
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 2 No. 1 (2019): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v2i1.2071

Abstract

Ammonium (NH4+) is a form of ammonia (NH) compound in thewater at low pH. The ammonium can cause poisoning in aquatic life. The purpose of this study was to determine the ammonium concentration in the Ngelom river water sample that flows in the Ngelom village, Taman district, Sidoarjo Regency. The measurement of ammonium concentration in river water samples was carried out using the UV-Vis spectrophotometrymethod with Nessler reagent based on the Nessler reagent reaction (K2HgI4) with ammonium in a base solution which would form a colloidal yellow brown dispersion which absorbance measured at 410 nm. Ammonium absorbance is proportional to the ammonium concentration in the sample. The sampling technique in this study used purposive sampling. Samples were taken at 10 trial points, every 5 meters to the right and left from the center point (Ngelom's River bridge to Maarif Hasyim Latif University). Ammonium concentration was determined in the linear concentration range of 1 – 5 mg/L with a correlation coefficiency value (r) of 0.9615 with limit of detection and limit of quantitation of 0.105 mg/L and 0.352 mg/L, respectively. The results of testing the river water samples showed that the ammonium concentration in 10 samples of river water ranged from 1.61 – 14.68 mg/L. All of the sample was not eligible requirements of the Republic of Indonesia PP No. 82 of 2001 about Water Quality Management and Water Pollution Control.
PENGUKURAN KADAR LOGAM Hg, KADMIUM, ARSEN, DAN KROMIUM (VALENSI 6) DALAM AIR SUMUR Ngibad, Khoirul
Lantanida Journal Vol 11, No 2 (2023)
Publisher : UIN AR-RANIRY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/lj.v11i2.18358

Abstract

The presence of metals such as Hg, Cd, As, and Cr6+ in waters can cause health problems. Hg poisoning causes central nervous system symptoms, Cd poisoning can cause digestive problems and kidney disease, As poisoning can cause jaundice, kidney bleeding, and skin cancer and Cr6+ is highly corrosive and can cause cancer. This study aimed to measure the levels of Hg, Cd, As, and Cr6+ in water wells in Taman District, Sidoarjo Regency. In this study, the AAS method was used at 253.7 nm for Hg analysis; 228.8 nm for Cd analysis; 193.7 nm on As analysis, and UV-Vis spectrophotometric method at 530/540 nm for Cr(VI) analysis. The water wells in Taman District, Sidoarjo Regency have Hg, As, Cd, and Cr6+ levels of 0.0006 each; <0.002; <0.0002; and <0.013 mg/L (well water A) and <0.0006; <0.002; <0.0002; and <0.013 mg/L (well water B). Based on the chemical parameters, it can be concluded that the levels of Hg, As, Cd, and Cr6+ still meet the quality standards (maximum levels).
PKM Strategi Pengembangan Petani Kopi Excelsa Wonosalam Desa Sumberjo Kecamatan Wonosalam Kabupaten Jombang Anam, Khairil; Arif, Donny; Putra, Bayu Charisma; Ngibad, Khoirul; Farkhan, M.; Andriansyah, Firman; Yanto, Fauzan Tri; Melinda, Selvina Dwi
Jurnal Pengabdian Sosial Vol. 1 No. 10 (2024): Agustus
Publisher : PT. Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/pp06cq66

Abstract

Wonosalam adalah salah satu daerah penghasil kopi terbaik di Kabupaten Jombang, Salah satunya adalah kopi jenis Excelsa. Berdasarkan hasil wawancara dan diskusi dengan mitra PKM, permasalahan utama yang dialami mitra PKM dalam aspek produksi yaitu mitra PKM belum menggunakan mesin produksi yang memiliki TTG (Teknologi Tepat Guna) seperti mesin pengupas biji kopi basah dan mesin penggiling pembuat bubuk kopi. Dalam aspek pemasaran yaitu mitra belum mempunyai branding label produk dan mitra belum mengetahui cara pemasaran menggunakan digital marketing. Dalam Aspek manajemen yaitu mitra belum memiliki aplikasi akuntansi penjualan dan mitra belum mempunyai ijin usaha. Tujuan kegiatan PKM ini adalah untuk mengatasi permasalahan prioritas yang sedang dihadapi mitra PKM baik dari aspek produksi, aspek pemasaran maupun aspek manajemen. Team PKM akan memberikan penyuluhan tentang pentingnya aspek  higienitas dalam proses produksi kopi excelsa serta melakukan pengadaan mesin pengupas biji kopi basah dan pengadaan mesin penggiling pembuat bubuk kopi. Dalam aspek pemasaran team PKM akan memberikan pelatihan branding pelabelan produk kopi dan memberikan pelatihan dalam pemasaran produk melalui digital marketing. Dalam aspek manajemen team PKM akan memberikan  pelatihan aplikasi akuntansi penjualan dan memberikan pendampingan pembuatan ijin usaha kepada mitra PKM. Kegiatan PKM ini dapat meningkatkan pengetahuan, keterampilan, jumlah produksi, jumlah omset, dan keuntungan mitra.
Peningkatan Penjualan Melalui Penggunaan Website pada UMKM Serbuk Minuman Herbal Farkhan, Muhammad; Aldimas, Reven; Anam, Khairil; Perdana, Dony; Lestari, Lilla Puji; Ngibad, Khoirul; Dianto, Annando Kusuma; Fahrudin, Ahmad Dani; Arrafi, David Khalik
Jurnal Pengabdian Sosial Vol. 1 No. 11 (2024): September
Publisher : PT. Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/h6y1kk57

Abstract

Dalam kegiatan Pengabdian kepada Masyarakat (PkM), kami bermitra dengan UMKM Queen Sae yang bergerak dalam pembuatan serbuk minuman herbal. UMKM Queen Sae telah memiliki P-IRT, sertifikat merek dan sertifikat halal. Mitra belum mempunyai websi teresmi yang berbayar tiap tahun. Mitra masih menggunakan website gratisan yang terkesan kurang profesional. Tujuan pelaksanaan PkM ini adalah untuk melakukan pendampingan usaha mitra dengan dalam pemasaran produk secara online menggunakan website sehingga dapat meningkatkan jumlah omset dan keuntungan mitra. Metode PkM ini adalah 1. Persiapan (tim PkM meliputi: pembuatan materi dan indikator – indikator penilaian keterampilan pengelolaan website), 2. Pelaksanaan (pelatihan dan pendampingan dalam pemasaran online melalui pembuatan dan pengelolaan website), dan 3. Monitoring dan evaluasi kegiatan PkM (hasil uji/skor dari beberapa kegiatan pelatihan dan pendampingan akan dikumpulkan untuk dilakukan analisis). Hasil PkM ini adalah mitra telah mempunyai website https://queensae.co.id/ untuk penjualan produk secara online. Ketrampilan mitra dalam mengelola website dibuktikan dengan kemampuan mitra dalam menguasai indikator-indikator penilaian keterampilan website yang mencapai 90%. Selain itu, juga terjadinya peningkatan omset dan pendapatan mitra yang mencapai 30-40%. Kegiatan PkM ini telah berdampak pada peningkatan penjualan melalui penggunaan website pada UMKM serbuk minuman herbal.
Aktivitas Antioksidan, Fenolik Total Dan Flavonoid Ekstrak Etanol Cangkang Kerang Simping Dan Cangkang Telur : Antioxidant Activity, Total Phenolic and Flavonoids of Ethanol Extracts of Scallop Shells and Egg Shells Ngibad, Khoirul; Muadifah , Afidatul; Sukmawati , Datin An Nisa
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol. 6 No. 1 (2024): Volume 6 No.1 (2024)
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v6i1.6389

Abstract

Cangkang kerang simping dan cangkang telur yang sering dianggap limbah berpotensi sebagai sumber antioksidan alami, mendukung kesehatan dan pengurangan limbah. Penelitian ini bertujuan mengidentifikasi aktivitas antioksidan, kadar fenolik, dan flavonoid dalam ekstrak etanol cangkang kerang simping dan cangkang telur. Ekstraksi dilakukan dengan merendam serbuk cangkang dalam etanol dan memekatkannya menggunakan rotary evaporator. Aktivitas antioksidan diukur dengan metode DPPH, sementara kadar flavonoid dan fenolik dianalisis menggunakan spektrofotometri UV-Vis dengan kuersetin dan asam galat sebagai standar. Cangkang telur memiliki kandungan flavonoid dan fenolik yang lebih tinggi dibandingkan cangkang kerang, yang mendukung potensinya sebagai sumber antioksidan yang lebih efektif. Cangkang kerang simping dan cangkang telur memiliki potensi sebagai sumber antioksidan alami, dengan cangkang telur menunjukkan efektivitas lebih tinggi karena kandungan flavonoid dan fenoliknya yang lebih tinggi. Temuan ini membuka peluang pemanfaatan cangkang kerang dan telur dalam produk nutraseutikal dan makanan fungsional untuk kesehatan.
Analisis Rasio Monosit terhadap Limfosit pada Penderita Osteoartritis di Surabaya Efawati, Susi; Ngibad, Khoirul; Raharjo, Budiono; Linggawan, Stephani; Sumarpo, Anton
MAHESA : Malahayati Health Student Journal Vol 5, No 5 (2025): Volume 5 Nomor 5 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i5.17922

Abstract

ABSTRACT Osteoarthritis is a degenerative joint disease characterized by progressive erosion of articular cartilage components. The known pathogenesis of osteoarthritis mainly includes immunological, bone metabolism, and biomechanical factors. Lymphocytes and monocytes are key regulatory cells for innate and acquired immunity, and monocyte-to-lymphocyte ratio may describe the immune status in osteoarthritis patients. This study aims to analyze the monocyte-to-lymphocyte ratio in osteoarthritis patients in Surabaya. This is an analytical observational research with a cross-sectional approach. The study was conducted in March - June 2024. The population in this study were osteoarthritis patients at Mitra Keluarga Hospital, Surabaya. The number of samples taken using the purposive sampling technique for this study was 31 people. The results showed that the average monocyte-to-lymphocyte ratio in osteoarthritis patients was 2.04. Meanwhile, the average monocyte-to-lymphocyte ratio in control subjects was 0.22. There was a significant difference in the monocyte-to-lymphocyte ratio between osteoarthritis patients compared to the control group. Keywords: Monocyte-To-Lymphocyte Ratio, Osteoarthritis, Joints  ABSTRAK Osteoartritis merupakan salah satu penyakit degeneratif pada sendi yang ditandai dengan erosi komponen kartilago artikular secara progresif. Patogenesis osteoartritis yang diketahui terutama mencakup faktor imunologi, metabolisme tulang, dan biomekanik. Limfosit dan monosit adalah sel kunci untuk imunitas bawaan dan didapat, dan rasio monosit terhadap limfosit menggambarkan status imunitas pada penderita osteoartritis. Penelitian ini bertujuan untuk menganalisis rasio monosit terhadap limfosit pada penderita osteoartritis di Surabaya. Penelitian ini dilakukan dengan metode analitik observasional dengan pendekatan cross-sectional. Penelitian dilakukan pada bulan Maret - Juni 2024. Populasi dalam penelitian ini adalah seluruh pasien osteoartritis di Rumah Sakit Mitra Keluarga, Surabaya. Jumlah sampel yang diambil dengan teknik purposive sampling untuk penelitian ini adalah sebanyak 31 orang. Hasil penelitian didapatkan rata-rata rasio monosit terhadap limfosit penderita osteoartritis sebesar 2,04 sedangkan rata-rata rasio monosit limfosit pasien kontrol adalah sebesar 0,22. Terdapat perbedaan yang signifikan pada rasio monosit terhadap limfosit antara penderita osteoarthritis dibandingkan dengan populasi kontrol. Kata Kunci: Rasio Monosit Terhadap Limfosit, Osteoartritis, Sendi
PENGARUH METODE MASERASI DAN SOKHLASI TERHADAP KANDUNGAN SENYAWA ANTIOKSIDAN DAUN Pluchea indica L. DENGAN METODE LC-MS Afidatul Muadifah; Tilarso, Dara Pranidya; Sowe, Momodou Salieu; Tarigan, Indra Lasmana; Ngibad, Khoirul; Yuliantari, Sonia Devi
Chempublish Journal Vol. 8 No. 2 (2024): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v8i2.36869

Abstract

Pluchea indica L. is a plant have some secondary metabolite compounds namely flavonoids, alkaloids, tannins, saponins, terpenoids, and phenols that have antioxidants activity. The purpose of this study was to compare the content of antioxidant compounds analyzed using LC-MS and determine the relationship of antioxidant activity through the DPPH test on P. indica leaves extracted by maceration and soxhlation. The extracts from maceration and soxhlation of P. indica leaves were analyzed using LC-MS to determine the composition of the compounds contained therein then continued with the antioxidant activity test using the DPPH method. In the antioxidant activity test using DPPH, each extract was made 3 variations of concentration, namely 10 ppm, 50 ppm, and 100 ppm, and measured based on the absorbance of DPPH at a wavelength of 515 nm using a UV-vis spectrometer. The results of analysis using LC-MS on macerated extracts of P. indica leaves are 112 compounds consisting of flavonoids 72.4841%, phenols 9.00625%, terpenoids 6.11827%, alkaloids 6.99075%, tannins 2.2256%, and saponins 2.04458%. The Soxhlet extraction contained 116 compounds consisting of flavonoids 67.14345%, phenols 8.95854%, terpenoids 13.82165%, alkaloids 5.35637%, tannins 2.53305%, and saponins 0.2969%. The results of the antioxidant activity test using DPPH on maceration extracts have an IC50 value of 76.7576 and soxhlation 62.580 ppm. Both maceration and soxhlation extracts of P. indica leaves contain compounds that have high antioxidant potential and have good antioxidant activity, namely in the strong antioxidant category. However, the soxhlation extract has more compounds and a lower IC50 value. Thus, the more antioxidant compounds contained in an extract, the lower the IC50 value so that the better the antioxidant activity.
Co-Authors Adhiba, Eka Indira Afidatul Muadifah Aldimas, Reven Ali Abraham, Ali Amanda, Lyrra Mirna Andriansyah, Firman Angge, Bagas Anton Sumarpo Ardiansah, Prianggara Arif Santoso Arif, Donny Arnando, Rasi Andante Arrafi, David Khalik As Syukri, Khoirul Anam Aulia, Rizza Fatma Ayu , Patricia Gaby Basyori, Imam Caesaria, Vica Ayu Candra Aldiansyah, Rio Chaniroh, St. Lutfi Choifin, Mochamad Cholik, Dimas Satria Nur Damayanti, Alvina Datin An Nisa Sukmawati Dianto, Annando Kusuma Dony Perdana Efawati, Susi Fafa , Angelica Rosia Fahrudin, Ahmad Dani Farichatul , Wachda Farkhan, M. Farkhan, Muhammad Galuh Puspita Sari Indra Lasmana Tarigan Islami, Putri Nova Nur Jannah Triarini, Lailatul Jannah, Elok Faiqotul Karel Damayanti, Novita Kholifah, Siti Nurriyatul Kristijono, Ary Laila Fitria Lilla Puji Lestari LINGGAWAN, STEPHANI Lukman Hakim Margalin, Brilliant Maulana, Nabilah Rosdiana Melinda, Selvina Dwi Merlina, Diana Mey Miftahul Jannah Miftakhul Huda Muadifah , Afidatul Muadifah, Afidatul Muhammad Aziz Muzakiyah, Nur Aini NURUL AZIZAH Pratama, Agung Firman Priambodo, Sigit Putra, Bayu Charisma Putri, Intan Syahrani RAHARJO, BUDIONO Rahma Diyan Martha Rahmatullah, Ilham Ramadani, Ade Ramadhina, Amanda Putri Ramadhini, Ananda Putri Rini, Yenny Puspa Rivaldo, M Ario Rizki Amalia, Laily Rodli, Achmad Fathoni Rosidin, Mochammad Khoirul Salsabila, Nabila Putri Saputra, Ahmad Bayu Saputra, Ifan Dwi Sari, Renny Nirwana Sari, Yuke Pramudita Sembilu, Nambi Setiawan Setiawan Sowe, Momodou Salieu Sukmawati , Datin An Nisa Sungging Pradana, Muhammad Tilarso, Dara Pranidya Tria , Novitasari Valenata, Valenata Wahyu Ningtias, Titis Wijayanti, Cicik Winarti, Siti Sri WULAN PURNAMASARI, WULAN Yanto, Fauzan Tri Yucha, Nikma Yuliantari, Sonia Devi Yusmiati, Siti Nur Husnul