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Jurnal Ilmiah Kedokteran Wijaya Kusuma
ISSN : 19782071     EISSN : 25805967     DOI : -
Core Subject : Health, Science,
Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.
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Articles 12 Documents
Search results for , issue "Vol 13, No 1 (2024): March 2024" : 12 Documents clear
D-Dimer As A Parameter Of Disease And Death Of Covid-19 Patients In Islamic Hospital, Surabaya Muzaijadah Retno Arimbi; Intan Nurani Indrajanu; Pratika Yuhyi Hernanda
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 1 (2024): March 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i1.3194

Abstract

Background: Previous studies of Community Associated Pneumonia (CAP) and Chronic Obstructive Pulmonary Disease (COPD), patients have shown that D-Dimer increases higher in severe cases and can be used as a prognostic biomarker and whilst D-Dimer> 1 mcg/ ml tends to be death for hospitalized adult patient with a diagnosis of Covid-19. However, D-Dimer's role in Covid-19 patients has not been fully studied.  We aim to conduct research on D-Dimer as a parameter of Clinical Severity and Death of Covid-19 Patients in Islamic Hospital, in Surabaya. Methods: This type of research is an analytic observational study with a retrospective approach. The population in this study were all patient’s data retrieved from the Dahlia Room’s database from June to July 2020 which were taken through EMR (an Electrical Medical Records) from a total of 189 patients with the total sample of 82 patients. Data analysis in this study used chi-square (X2) with a significant value of p <0.05. Results: Age over 60 years is associated with a higher risk of severe Covid-19 infection (P<0.05). A history of hypertension significantly affects the severity of Covid-19 infection (P < 0.05). The proportion of recoveries (53.7%) was higher than the number of deaths (46.3%), although the majority of patients experienced severe clinical severity (39%).  Laboratory parameters, such as D-dimer values, correlated significantly with patient age (P = 0.027, <0.05). Conclusion: The study highlights the importance of factors such as age and history of comorbid diseases in predicting the severity of Covid-19 infection. A better understanding of these risk factors can help in more effective management and management of Covid-19 patients.
Association of Vitamin D Intake in Pregnant Women and Birth Weight Cindy Rolexza; Fathia Meirina
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 1 (2024): March 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i1.2712

Abstract

Background: Insufficient maternal consumption of vitamin D can have adverse effects on fetal development and increase the likelihood of low birth weight. This research aimed to establish the correlation between the quantity of vitamin D consumed by expectant mothers and the weight of newborns. Methods: This study utilized an analytical observational design with a cross-sectional approach, collecting data from August to November 2022. Information on Vitamin D intake and birthweight was obtained via questionnaire interviews with 96 pregnant women delivering at the University of North Sumatera Hospital or Maharani Women’s and Children Hospital. Semi-Food Frequency Questionnaires (FFQs) served as the data collection instrument. Non-probability consecutive sampling was employed. Statistical techniques, including Chi-square and Fisher's Exact test, were used for data analysis. Findings indicated a prevalence of inadequate vitamin D intake among mothers (3.125%). The mean daily consumption of vitamin D among expectant women was 19.99 μg/day. Mother's education level did not significantly influence the outcome (p=0.589). Results: The results of this study suggest that there was no significant association between maternal age at pregnancy (p=0. 135), gestational age (p=0. 771), parity (p=0958), and baby's sex (p=0. 448) with birth weight. Conclusion: An observed association existed between the prenatal intake of vitamin D and neonatal birth weight in expectant mothers.
Isolation and Characterization of Lactic Acid Bacteria From Sago Wastewater As Antibacterial Satwika Tri Rahmadana; Eka Astuty; Ony Wibriyono Angkejaya
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 1 (2024): March 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i1.3022

Abstract

Background: Foodborne diseases are infections of the gastrointestinal tract caused by food containing microbiological agents and usually, these infections affect groups of individuals who have low immune systems. Lactic acid bacteria (LAB)are bacillus-shaped Gram-positive bacteria that work by inhibiting pathogenic bacteria that cause foodborne diseases. Maluku is a region in Indonesia rich in sago production.  Sago ihur (Metroxylon sylvestre) and tuni (Metroxylon rumphii) are types of sago commonly found in Maluku. Sago is rich in carbohydrates and therefore has the opportunity to produce LAB. This study aimed to isolate and characterize LAB from sago wastewater was a laboratory experimental research with descriptive method using primary data. Methods: Bacterial isolation was carried out using a selective media. Characterization carried out by macroscopicly characterization by observing shape, margin, elevation, pigmentation, appearance, optical properties, and texture. Microscopic characterization was performed using Gram and spore staining. Results: The results of this study showed that five bacterial isolates (I1, I2, T3, T4, and I5) were successfully isolated in a round shape, flat edges, yellowish white color (not pigmented), shiny appearance, and mucoid texture, but isolate T3 showed a raised elevation and translucent to light (transparent), while for other isolates it was convex and translucent, and non-spore forming gram positive. Conclusion: Antibacterial tests against S. aureus and E. coli showed no inhibition zones. LAB isolates from sago wastewater showed no significant antibacterial effect
Preface March 2024 Putu Oky Ari Tania
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 1 (2024): March 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i1.3656

Abstract

Routine hematology description and D-dimer COVID-19 patients at Sidoarjo Regional Hospital Nugroho Eko Wirawan Budianto; Budhi Setiawan; Nugrahadi Dwi Pasca Budiono
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 1 (2024): March 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i1.3537

Abstract

Background: COVID-19, caused by the SARS-COV-2 virus, is a contagious and potentially fatal disease that is commonly diagnosed using real-time reverse polymerase chain reaction (RT-PCR) assay. Studies have shown that the D-dimer level and the features of hematological exams can offer important prognostic value of the patients. This study aimed to describe data about the routine hematology features and D-Dimer levels of hospitalized COVID-19 patients in Sidoarjo Regional Hospital. Methods: This study used a retrospective, cross sectional, observational approach with descriptive analysis. Medical records of 167 COVID-19 patient were collected based on the criteria. The outcomes of the D-dimer and complete blood count of the patients were summarized. Results: According to the findings, the number of the patients with COVID-19, 53 (31.7%) were between the ages of 31 and 35, and at least 36 (21.6%) were between the ages of 17 and 30. Prominent hematology routine outcomes were the number of patients with anemia (103 or 61.7%), neutrophilia (105 or 62.9%), and lymphocytopenia (129 or 77.2%). The D-dimer value increased by 93 (55.7%) patients among 167 COVID-19 patients. Conclusion: Therefore, monitoring the patient's routine hematological presentation and D-dimer level during treatment is essential for preventing mortality and morbidity.
Laser Hemorrhoidoplasty Using Reusable Bare Fiber Combined Mucopexy on Grade IV Internal Hemorrhoid: A Case Report Fadli Robby Amsriza; Rizka Fakhriani
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 1 (2024): March 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i1.2874

Abstract

Background: Hemorrhoids are the most common anorectal disease, affecting millions worldwide. Hemorrhoids are categorized as "internal" or "external" based on their proximity to the pectinate line, which separates the upper 2/3 and lower 1/3 of the anus. The hemorrhoidal disease can be treated in various ways, from non-invasive methods like rubber band ligation, cryotherapy, sclerotherapy, laser photocoagulation, and phototherapy to invasive methods like surgical excision for patients with severe symptoms, grade III or IV hemorrhoids, or persistent bleeding. This study described the results of Laser Hemorrhoidoplasty (LHP) using reusable bare fiber combined mucopexy, a diode laser with wavelengths of 980 nm and 1470 nm, specifically gallium aluminum arsenide (GaAIAs). Methods: a case of a 28-year-old male with complaints of rectal prolapse mass one day ago and could not be reinserted with a finger, bleeding while passing stool, and rectal pain with a Visual analog scale was 7. The patient had experienced similar symptoms and had a sclerobanding procedure four years ago. However, it has reappeared in the past year. The patient was diagnosed with grade 4 internal hemorrhoids and underwent Conclusion: Laser hemorrhoidoplasty using reusable bare fiber with combined mucopexy. After the laser hemorrhoidoplasty procedure on day 4, the patient felt no pain, rectal bleeding, rectal lumps, or soiling.
Role of Anemia and Leukocytosis as Severity Predictors of Coronary Artery Disease Stenosis : A Retrospective Cross-sectional Study M Saugi Abduh; Muhammad Rizki Triono; Retno Widyastuti
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 1 (2024): March 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i1.3555

Abstract

Background: Anemia and leukocytosis were found to be associated with conditions that higher the risk for the formation of atherosclerotic plaque which will develop into cardiovascular disease. Basic laboratory parameters such as anemia and leukocytosis are not routinely used to assess Coronary Artery Disease (CAD) severity based on its stenosis. This study aimed to analyze the role of simple laboratory examiantion anemia and leukocytosis as predictors of the severity of stenosis in CAD. Methods: Cross-sectional approach was used in this study. Secondary data on CAD patients treated at Sultan Agung Islamic Hospital Semarang in 2022 were analyzed. Anemia and leukocytosis are the main risk factors analyzed in this study. Other risk factors such as gender, age, smoking status, hypertension and diabetes mellitus (DM) were also included in the analysis of this study. We performed bivariate analysis and multivariate analysis to see the relationship between these risk factors and the CAD stenosis severity. Results: Bivariate analysis with chi-square showed that anemia had a significant relationship with CAD severity (P<0.05). Multivariate analysis between anemia and smoking status reported that anemia was the most significant risk factor for the CAD stenosis severity (P<0.05). Conclusion: No association found between leukocytosis and CAD severity.
Effect of Ginger Extract in Lowering Blood Pressure in The Elderly with Hypertension Ulkomah Ulkomah; Desridius Chalid; Farida Murtiani; Aninda Dinar Widiantari
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 1 (2024): March 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i1.2986

Abstract

Background: Hypertension is a cardiovascular disease that is common to find in elderly. Its prevalence reached to 22% throughout the world in 2020. Pharmacological treatment to hypertension involves lifetime commitment to drug adherence. Ginger extract as complementary therapy has been widely common in Indonesia to reduce common flu symptoms and indigestion. It acts as a therapeutic effect that boosts immune system, improving the cardiovascular system by reducing the level of low-density lipoproteins and cholesterol. Prior studies showed its effect in lowering blood pressure in hypertension patients, while several other said the effect was stronger in less than 50 years old people. The aim of the study was to analyze red ginger extract as main therapy in hypertension in elderly. Methods: This study was a quasi-experimental with one group pretest-posttest without control group. Participants were 45-65 years old hypertension patients in Semper Barat II Primary Health Care. Intervention was 4 grams of minced ginger then added by 2 spoons of honey in 100 ml of water. The drink was consumed in 5 days. Results: Average age of participants were 62,9 (60-65) years old. Before intervention, mean blood pressure was 156,8 (140-180) / 98,03 (85-115) mmHg and lowered to 148,6 (125-170) / 92,57 (80-110) mmHg after 5 days of intervention (p=0,0001). Conclusion: We recommend ginger extract as an alternative to reduce blood pressure in elderly with hypertension. We hoped the results will become a new approach to treat hypertension.
Effect of Submaximal Exercise on Trained and Untrained Intensity on Estrogen Levels in Female White Rats (Rattus Norvegicus) Wistar Strains Cinthya Fitri Paramitha; Mita Herdiyantini; Eric Mayo Dagradi; Annisa Ulya Rasyida
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 1 (2024): March 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i1.2893

Abstract

Background: Trained and continuous physical activity can increase estrogen levels in women, while irregular activity can increase excessive Estrogen levels. Submaximal exercise is a recommended exercise to improve a woman's physiological function The purpose of this experiment was to determine the effect of submaximal exercise on trained and untrained intensity on Estrogen levels in female white rats (Rattus norvegicus) Wistar strains. Methods: This research was an experimental study using a post-test-only control group design using 30 female Wistar rats which were divided into 5 groups: control group not treated (K1), experimental group of animals with exercise intensity without intervention (K2), group of experimental animals with untrained intensity without intervention (K3), group of experimental animals with exercise intensity with intervention (K4), and experimental group of animals with exercise intensity with intervention (K4). experimental animals with untrained intensity treatment with intervention (K5). The intervention was swimming at moderate intensity with a duration of 85% of the maximum time to swim and a load of 8% of the rat's body weight. After the treatment period, all groups were terminated to take intracardiac blood measured using ELISA. Results: The data results were analyzed using statistical tests. The results of this study found that the trained group had lower Estrogen levels compared to the untrained group, but higher than the control group. The Kruskal-Wallis test show a significance value (p = 0.157), p> 0.05. Conclusion: In this study, there was no effect of submaximal exercise between trained and untrained intensity on Estrogen levels in Wistar strain female white rat.
Effect of Oatmeal on TNF-alfa of Blood of White Rats Exposed to Motor Vehicles Fumes Sukma Sahadewa; Fara Disa Durry; Zulfan Febriawan; I Putu Agus Aris Wijaya Kusuma
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 1 (2024): March 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i1.3421

Abstract

Background: Air pollution due to motor vehicle emissions causes several serious health problems including respiratory problems. Fumes exposure activated alveolar macrophages and epithelial cells release mediators such as LTB4, TNF-α, and IL-8. TNF-α are known induced acute inflammation and tissue damage. Oats are plant with high dietary fiber content and nutritional value. Oats are contain of antioxidant compounds source such as tocopherols and avenanthramides. Therefore, this research aims to determine the effect of oatmeal on TNF-α of white rats exposed to motor vehicle fumes. Methods: This research used true experiment design with Randomized Post-Test Only Control Group design using 16 white male rats divided into three groups: control group only was given standard fed (K1), second group was given standard fed and exposed with motor vehicle fumes (K2), third group was given standard fed mixed with 10 gr of oatmeal and exposed with motor vehicle fumes (K3) for ten days. After ten days of the treatment, blood of white rats from all groups will be taken intracardial then measured TNF- α levels. Results: Statistical test analyzed using SPSS Software 23. Oatmeal has an effect to decrease TNF-α levels (P<0.001). Conclusion: This study conclude that oatmeal can help reduce TNF-α levels when exposed to motor vehicle fumes.

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