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Jurnal Ilmiah Kedokteran Wijaya Kusuma

JIKW
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Published by Universitas Wijaya Kusuma Surabaya

ISSN : 19782071 EISSN : 25805967 DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.

Arjuna Subject : -

Articles 390 Documents

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Enterobakter Sakazakii (Cronobacter sakazakii): Sebagai bakteri pencemar susu bubuk formula bayi Asih Rahayu
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2011): Volume II, Nomor 1, Januari 2011
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v2i1.2188

Enterobacter sakazakii (Cronobacter sakazakii) adalah bakteribatang gram negatif, fakultatif anaerob dari famili enterobacteriaceae.

Pengaruh Pemberian Jus Tomat (Solanum lycopersicum L.) terhadap Kadar Kolesterol LDL Tikus Putih (Rattus norvegicus) Jantan Galur Wistar yang Diinduksi Aloksan Leny Alimatul Husna; Louis Djoko; Fitri Handajani; Tri Martini
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 8, No 1 (2019): EDISI MARET 2019 (available online since April 2019)
Publisher : Universitas Wijaya Kusuma Surabaya

Hiperkolesterolemia merupakan faktor resiko terjadinya gangguan kardiovaskuler pada diabetes mellitus. Pada diabetes mellitus kekurangan insulin meningkatkan lipolisis sehingga asam lemak bebas meningkat sehingga meningkatan kadar kolesterol total dan kolesterol LDL. Tomat mengandung likopen yang dapat menurunkan kadar kolesterol LDL karena mampu menghambat HMG-KoA reduktase. Penelitian ini untuk mengetahui pengaruh pemberian jus tomat (Solanum lycopersicum L.) terhadap kadar kolesterol total dan LDL tikus putih (Rattus norvegicus) jantan galur wistar yang diinduksi aloksan. 24 ekor yang dibagi menjadi 3 kelompok: 1). Kelompok kontrol negatif tanpa perlakuan 2). Kelompok kontrol positif hewan coba yang diinduksi aloksan 3). Kelompok perlakuan yang diinduksi aloksan dan diberi jus tomat dengan dosis 11 gram/KgBB selama 14 hari. Uji One-Way Annova menunjukkan peningkatan kadar kolesterol LDL yang signifikan antara kelompok kontrol positif dan kelompok hewan kontrol negatifnamun tidak pada kadar total kolesterol. Rerata kadar total kolesterol dan LDL pada kelompok perlakuan menunjukkan penurunan yang tidak signifikan di bandingkan kelompok hewan coba yang diinduksi aloksan. Pemberian aloksan dengan dosis 150 mg/Kg BB dapat meningkatkan kadar kolesterol LDL secarabermakna namun tidak pada kadar total kolesterol. Pemberian jus tomat dengan dosis 11 gram/KgBB cenderung menurunkan rerata kadar total kolesterol dan LDL.

Effect Of Intaking High-Fat Diet On White Rat’s (Rattus norvegicus)Blood Lipid Profil Made Subawa Harsa
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 1 (2014): Edisi Maret 2014
Publisher : Universitas Wijaya Kusuma Surabaya

Obesity and metabolic syndrom are characterized by dislipidemia. One of methods that is performed to increase body fat contents is by intaking of high-fat diet. The purpose of this study was to demonstrate the effect of a dietary intake of high-fat on the lipid profile (total cholesterol, HDL, LDL, and triacylglycerol) in white rat (Rattus norvegicus). This research was tested on 30 white rats that were divided into 2 randomized groups, and were treated for 4 weeks. Group 1 (K1) : was treated with standard diet, (K2) : with standard and high-fat diet. The results showed that intaking high-fat diet increases the total cholesterol content, triacylglycerol, LDL cholesterol, and decreases HDL cholesterol content.

Infeksi COVID-19 pada kehamilan dengan insulin dependent diabetes mellitus (IDDM) Arif Rahman Nurdianto; Rizal Fauzi Nurdianto; Dyah Ayu Febiyanti
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 9, No 2 (2020): SEPTEMBER 2020
Publisher : Universitas Wijaya Kusuma Surabaya

Research on pregnancies with insulin dependent diabetes mellitus (IDDM) infected with COVID-19 is very limited. In pregnant conditions, there is a shift from Th1 to Th2 and physiological changes that make it very susceptible to being infected by COVID-19 in pregnancy, in addition to complaints that are similar between changes due to pregnancy and symptoms of COVID-19. The aim of this study was to Explain the effect of COVID-19 infection in pregnant women with IDDM. This study was conducted using a descriptive method of clinical and laboratory examination results of one pregnant patient aged 26 years with IDDM and infected with COVID-19 at the Trosobo Health Center. The variables in this study were the results of clinical and laboratory examinations of patients during treatment. All data were then analyzed descriptively according to the latest journal literature. Result of this study showed that Pregnant women with IDDM and infected with COVID-19 might have disorders of the lung organs in the form of pneumonia on X-rays, disturbances in laboratory test and minor clinical disorders. In addition, it is important to note that the presence of heart problems as indicated by disturbances in the rhythm of the post partum ECG. COVID-19 infection in pregnant women with IDDM can show mild or severe symptoms such as heart problems and further research is needed on the effect of this infection with a larger sample.

Interaksi obat Herni Suprapti
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 3 (2011): Volume Edisi Khusus Desember 2011
Publisher : Universitas Wijaya Kusuma Surabaya

Banyak pasien, terutama orang tua diperlakukan terus menerus dengan satu atau lebih obat untuk penyakit kronis seperti hipertensi, gagal jantung, osteoarthritis dan sebagainya.

Pengaruh Ekstrak Tamarindus indica Terhadap Kenaikan Berat Badan Pada Tikus Rattus norvegicus Yang Diberi Diet Obesitas Candra Rini Hasanah Putri; Titiek Sunaryati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 6, No 1 (2017): Edisi Maret 2017
Publisher : Universitas Wijaya Kusuma Surabaya

Obesity is a health problem whose prevalence tends to increase in Indonesia. Obesity becomes a concern, because it is one of the parameters that often followed by impaired of glucose tolerance in the metabolic syndrome. In Indonesia, Tamarindus indica is believed as a body slimming substance so it has possibility to become an alternative therapy that is easily available and cheap for obesity. The purpose of this study was to determine the ability of Tamarindus indica in inhibiting obesity. This experiment used 28 male Wistar strains in 2-3 months age that were divided into groups: group 1 (negative control, normal diet without Tamarindus indica), group 2 (positive control, obese diet without Tamarindus indica), group 3 (obese diet + Tamarindus indica 2700mg/kg BW), and group 4 (obese diet + Tamarindus indica 3600mg/kg BW). Measurement were performed in the first day after acclimization before treatment (day 8), and repeated weekly afterwards, ie at day 15, 22, 29, 36, and 43. Anova and Tukey Simultaneous statistics test were performed to see the differences in wight gain per week compared with the first week of study, then compared between groups. Furthermore, a virtual screening that called insilico bioinformatics analyzes was performed to test the binding activity between quercetin and rutin (compounds in Tamarindus indica) with fatty acid synthase, an enzym that plays a role in de novo synthesis of fatty acids. Tamarindus indica was shown to significantly inhibit weight gain in rats with obese diet food (P=0.000), but differences dose of Tamarindus indica did not appear to have significant effect to inhibit obesity (P=0.321). The ability of Tamarindus indica is due to the compounds quercetin and rutin, where these two ingredients estimated to have the ability to inhibit fatty acid synthase with high strength.

Hormone Therapy as A New Hope for Achondroplasia Patients Basuki Supartono; Ayola Dewi Utami; Abyanka Rayhan Fuadi; Bintang Bayu Aryandi
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 11, No 1 (2022): MARET 2022
Publisher : Universitas Wijaya Kusuma Surabaya

Achondroplasia is a disorder of child bone growth due to gene mutation of growth factor receptor. Short stature is a major problem. Efforts to increase height are still a challenge. The method performed so far is the lengthening of the limbs with various complications and risks of re-surgery. A promising new alternative without surgery is the administration of growth hormone therapy. This review aims to find out the safety and effectiveness of hormone therapy. The review method used is a narrative review. The review results showed that growth hormone therapy is safe and effective. The review concludes that growth hormone therapy has been proven to be safe and effective in increasing the height of achondroplasia patients.

Pemanfaatan Seduhan Daun Ashitaba dengan Simvastatin dalam Menurunkan Kadar LDL Tikus Putih Jantan Strain Wistar Ernawati Ernawati; Theresia Ratnasari Widjaja
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 7, No 1 (2018): edisi Maret 2018
Publisher : Universitas Wijaya Kusuma Surabaya

High levels of blood cholesterol or hypercholesterolemia is an important risk factor for a cardiovascular disease. In order to overcome this problem, giving statins drug such as simvastatin is an intervention that is often applied. Besides using this drug, it can also be accompanied by consuming herbal plants which is Ashitaba leaves (Angelica keiskei). It contains Chalcones which demonstrates anti tumour property and also antioxidant activity that can lower cholesterol levels, especially LDL in the blood. This study aimed to investigate the effect of Ashitaba leaves (Angelica keiskei) steeping administration in assisting simvastatin drugs to decrease the levels of Low Density Lipoprotein (LDL) in the blood serum of male white rats Strain wistar (Rattus Norvegicus) with hypercholesterolemia. The population for this study was male white rats Strain wistar (Rattus Norvegicus) with samples taken in this study were 33 white rats. Data analysis for this study is using One Way Anova test.The result showed that supplementation of simvastatin treatment using steeping Ashitaba leaves might slightly reduce LDL level among male white rats Strain wistar (Rattus Norvegicus) with hypercholesterolemia. However, the result demonstrated not significant different. To assist simvastatin drugs in lowering LDL levels in male white rats Strain wistar (Rattus Norvegicus) which is made to be hypercholesterolemia can lower LDL levels slightly but not significantly (p-value = 0,177) which is >a (0,05).

PARKINSON’S DISEASE Titiek Sunaryati
Jurnal Ilmiah Kedokteran Wijaya Kusuma No 1 (2011): Edisi Juli 2011
Publisher : Universitas Wijaya Kusuma Surabaya

Parkinson's disease is a degenerative disorder of the central nervous system that often impairs thesufferer's motor skills, speech, and other functions. Parkinson's disease affects movement (motorsymptoms). Other typical symptoms include disorders of mood, behaviour, thinking, and sensation (nonmotorsymptoms). The symptoms of Parkinson's disease result from the greatly reduced activity of thedopaminergic neurons, which are primarily in the pars compacta region of the substantia nigra. Reviewsof depression estimate its occurrence in anywhere from 20-80% of cases. PD is not considered to be afatal disease by itself, but it progresses with time.

PCR and Southern Blot for Lymphoma Maligna Titiek Sunaryati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2011): Volume II, Nomor 1, Januari 2011
Publisher : Universitas Wijaya Kusuma Surabaya

Analisis Blot Southern tetap menjadi standar emas untuk mendeteksi T-Sel Reseptor antigen (TCR) penyusunan ulang gen, biasanya target gen TCR karena penataan-kembali TCR terlalu terbatas untuk membedakan andal monoklonal dari populasi T-sel poliklonal.

Page 30 of 39 | Total Record : 390

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Jawa timur

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