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INDONESIA
Paediatrica Indonesiana
Published by Ikatan Dokter Anak Indonesia
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 2,112 Documents
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Surgical aspects of arachnoid cysts: report of 3 cases and brief review Eka J. Wahjoepramono
Paediatrica Indonesiana Vol 48 No 3 (2008): May 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4063.387 KB) | DOI: 10.14238/pi48.3.2008.186-92

Abstract

This paper reports two cases with surgicalintervention and another case with non-surgicaltreatment.
Relationship of obesity and secondary sexual development in girls Ida Ayu Sri Kusuma Dewi; Soetjiningsih Soetjiningsih; Yudha Patria
Paediatrica Indonesiana Vol 50 No 1 (2010): January 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (437.465 KB)

Abstract

Background Obesity is a pathological condition due to consumption of excessive amount of food and is associated with early sexual maturation and irregular cycle of menstruation. Early sexual maturation is estimated from the age of menarche.Objective To determine relationship of obesity and age of secondary sexual development in girls.Methods This cross-sectional study was performed on all elementary school students in 4 sub-districts at Denpasar. Nutritional status was determined by BMI. Radiologic examination was performed to determine the bone age. Data were analyzed with appropriate statstical methods.Results Mean chronological age of breasts development for B2 and B3 stage on obese group was younger than non-obese groups (9.0 vs 9.9, P = 0.001; 9.7 vs 10.9, P = 0.006). Early menarche more frequent in obese group than non-obese groups {PR 5 (CI 95% 1.33 to 19.71)}. Mean age of children who experienced menarche on obese group was younger than non-obese group {10.9(SD 0.61) vs 11.1 (SD 0.28). Univariate analysis showed that maturation age of secondary sexual development on obese groups was differed with non-obese group {8.9 (SD 0.21) vs 9.4 (SD 0.13). Linear regression analysis showed relationship between age of breasts and pubic hair growth on both groups.Conclusions This study established that mean age of secondary sexual development was younger in obese girl than non-obese group. Bone age range on obese girls was wider than non-obese girls. [Paediatr Indones. 2010;50:49-5].
Fava bean–induced hemolytic crisis in glucose-6-phosphate dehydrogenase deficiency IPG Karyana; IB Mudita
Paediatrica Indonesiana Vol 43 No 6 (2003): November 2003
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (229.568 KB) | DOI: 10.14238/pi43.6.2003.230-3

Abstract

This paper reports a case of hemolytic crisis dueto fava beans in a child with G6PD deficiency.
Pulse pressure variation and systolic pressure variation in mechanically ventilated children Johnny Nurman; Antonius H. Pudjiadi; Arwin A. P. Akib
Paediatrica Indonesiana Vol 51 No 1 (2011): January 2011
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi51.1.2011.34-40

Abstract

Background In mechanically ventilated patients, changes in breathing patterns may affect the preload, causing stroke volume fluctuation. Pulse pressure variation (PPV) and systolic pressure variation (SPV) are dynamic means of the hemodynamic monitoring in ventilated patients. No study on PPV and SPY in children has been reported to date.Objective To study changes in PPV and SPY values in mechanically ventilated children.Method A descriptive cross􀁏sectional study was done at the Pediatric Critical Care Unit (PICU), Cipto Mangunkusumo Hospital, Jakarta. Subjects were mechanically ventilated children aged > 12 months. Echocardiography was performed in all patients to determine the cardiac index. Arterial pressure was measured by connecting an arterial line to a vital signs monitor. PPV and SPV were calculated using the standard formulas. Bivariate correlation tests were performed between cardiac index and PPV and between cardiac index and SPV. Receiver operator characteristic (ROC) curve analysis was done to determine the optimum PPV and SPV cut-off points to predict normal cardiac index (2:3.5 L/minute/m2).Results Eighteen patients were enrolled in the study, yielding 48 measurements. Mean cardiac index was 2.9 (SD 1-2.6) L/minute/m2. Median PPV was 18.9 (range 4.1-45.5)% and SPV was 12.1 (range 3.8- 18.9)%. We found strong negative correlations between PPY and cardiac index (r= ; p = ) and SPY and cardiac index (r= ; p = ). To predict nonnal cardiac index, the optimum cut-off point was 11.4% for PPV (100% sensitivity, 100% specificity) and 9.45% for SPV (91.7% sensitivity, 100% specificity).Conclusion In mechanically ventilated children, cardiac index is negatively correlated with PPV and SPV.
Lactose tolerance test on Indonesian newborn infants Achmad Surjono; Surjantoro Surjantoro; Tonny Sadjimin; Ismangun Ismangun
Paediatrica Indonesiana Vol 13 No 1 (1973): January 1973
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi13.1.1973.11-6

Abstract

It is well accepted that milk is the only source of nutrition for newborn infants. Human milk as well as cow's milk contains a considerable amount of specific carbohydrate, namely lactose. Lactose must be hydrolyzed into its components monosaccharides, glucose and galactose by small intestinal enzyme lactase in order to be utilized.
Procalcitonin vs. the combination of micro-erythrocyte sedimentation rate and C-reactive protein for diagnosing neonatal bacterial sepsis Afifa Ramadanti; Renya Hiasinta; Herman Bermawi; Erial Bahar
Paediatrica Indonesiana Vol 57 No 4 (2017): July 2017
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (251.643 KB) | DOI: 10.14238/pi57.4.2017.205-10

Abstract

Background Given the high rates of mortality and morbidity in neonatal sepsis, rapid, easy-to-use, and inexpensive biomarkers with high sensitivity and specificity are needed to diagnose neonatal sepsis. Procalcitonin is often used as a predictor in identifying neonatal sepsis, but C-reactive protein (CRP) and micro-erythrocte sedimentation rate (m-ESR) may also be valid biomarkers of neonatal sepsis.Objective To compare the accuracy of procalcitonin to the combination of CRP and m-ESR, as well as to find cut-off points for the three tests, in diagnosing bacterial neonatal sepsis.Methods Subjects were neonates hospitalized from July to October 2016 in Mohammad Hoesin Hospital, Palembang with sepsis at clinical presentation and healthy neonates with sepsis risk factors. All subjects underwent complete blood counts, CRP, m-ESR, blood cultures, and  procalcitonin examinations.Results Ninety-four infants were included, of whom 26 had proven sepsis. The combined values of m-ESR and CRP had 85% sensitivity, 59% specificity, and 66% accuracy. A procalcitonin (PCT) cut-off point of 9.7ng/mL showed 100% sensitivity, 96% specificity, and 97% accuracy level, which were significantly higher than the combined values of m-ESR and CRP.Conclusion The combined values of m-ESR (13 mm/hour) - CRP (17 mg/dL) and procalcitonin alone (2ng/mL) are both valid for the diagnosis of bacterial neonatal sepsis, but the accuracy of procalcitonin at 9.7ng/mL is significantly greater. 
Efficacy of dioctahedral smectite in infants with acute diarrhea: a double blind randomized controlled trial A. A. Made Widiasa; Soetjiningsih Soetjiningsih; Putu Gede Karyana
Paediatrica Indonesiana Vol 49 No 1 (2009): January 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (113.069 KB) | DOI: 10.14238/pi49.1.2009.48-53

Abstract

Background  Acute  diarrhea  is  a sudden diarrhea which lasts lessthan  seven days  on  babies and children.  The  standard  treatmentby  WHO  in managing acute diarrhea  is  still  not  satisfactory forparents whose infants and children suffering from the disease.Dioctahedral  smectite  is  expected  to  decrease  the  volume,frequency, and duration  of  diarrhea.Objective  To  assess the clinical effects  of  dioctahedral smectite ininfants with acute diarrhea.Methods  A double-blind, randomized clinical controlled trial wasperformed on six to  12  months-old infants who were hospitalizedin Sanglah Hospital, Denpasar due to acute diarrhea .The subjectswere divided into two groups.  The  treatment  group was givenstandard  management  with  adjuvant  dioctahedral  smectitewhile  and  control group was given standard management withplacebo.Results  From  68  infants enrolled in this study, the  mean  durationof  diarrhea was significantly shorter in treatment group comparedto placebo group  [39.03  hours (SD  2.03)  vs  70.58  hours (SD3.78),  mean  difference  31.6 (95%  CI  22.90  to  40.19), P=0.001].The  RRR was  50%,  and  ARR  was  29%.  Kaplan-Meier survivalanalysis showed  that  duration  of  acute diarrhea was shorter intreatment  group  [36  hours (SD  1.7)  versus 72 hours (SD  4.18),mean difference  36.0 (95%  CI  21.81  to  50.19),  log rank test,P<0.0001].  In multivariate Cox regression analysis, it was foundthat  dioctahedral smectite influenced the duration  of  diarrheain infants with acute diarrhea  [OR  4.403 (95%  CI  2.39  to  8.12),P<O.OOOl].Conclusion  Dioctahedral smectite  can  shorten the duration  ofacute diarrhea.
Hematological scoring system as an early diagnostic tool for neonatal sepsis Fathia Meirina; Bidasari Lubis; Tiangsa Sembiring; Nelly Rosdiana; Olga Siregar
Paediatrica Indonesiana Vol 55 No 6 (2015): November 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (112.432 KB) | DOI: 10.14238/pi55.6.2015.315-21

Abstract

Background Sepsis was the leading cause of death in babies by 30%-50% in developing countries. Early diagnosis of neonatal sepsis is still a difficult problem because of clinical features are not specific. Blood culture is the gold standard, but it takes several days and is expensive. The hematological scoring system (HSS) consists of hematologic parameters (leucocyte count, polymorphonuclear (PMN) cells, degenerative changes, and platelet count) for early diagnosis of neonatal sepsis. Objective To measure HSS as an early diagnostic tool for neonatal sepsis. Methods A cross sectional study was conducted in March to June 2013. Samples were collected by consecutive sampling. Fourty neonates suspected sepsis in neonatology unit H. Adam Malik Hospital, Medan, North Sumatera, underwent routine blood count, blood culture, and peripheral blood smear. Each hematologic parameters were analysed using the HSS of Rodwell et al. The hematologic parameters were total leucocyte count, total PMN cells, total PMN immature, I:T PMN ratio, I:M PMN ratio, degenerative changes, and platelet count. The total value revealed HSS score. Diagnostic study parameters were calculated. Results Ten of fourty neonates had sepsis based on blood culture results. The HSS score >=4 had sensitivity 80%, specificity 90%, with positive predictive value (PPV) 73%, negative predictive value (NPV) 93%, ROC curve showed cut off point 0.902 (95% CI 0.803 to 1.0). Conclusion Score HSS >=4 could be used as an early diagnostic tool for neonatal sepsis.
Effectiveness of lactose-free formula in management of acute rotavirus diarrhea I. Nyoman Budi Hartawan; S. Yati Soenarto; I. K. G. Suandi
Paediatrica Indonesiana Vol 49 No 5 (2009): September 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.632 KB) | DOI: 10.14238/pi49.5.2009.299-303

Abstract

Background Acute rota virus diarrhea causes mucosal destruction, blunted villi, villus shortening, and death of cells. The process also decreases lactose secretion which responsible in lactose absorption. Non-absorbed lactose then causes the progression of osmotic and secretory diarrhea causing delayed recovery. Lactose-free formula may decrease lactose, thus shortened the duration of diarrhea episode.Objective To compare the cure rate and duration of acute rota virus diarrhea in children treated with lactose-free formula and lactose containing formula.Methods A randomized, double-blind controlled trial was performed to infants and children aged 2: 6 to 59 months old with acute rotavirus diarrhea accompanied with mild or moderate dehydration that were admitted to pediatric gastroenterology division. Latex agglutination test was used to detect rota virus. After an appropriate rehydration therapy had been done, they were fed with either lactose-free formula (n = 29) or lactose-containing formula (n = 31). Comparisons between duration of diarrhea, weight gain, and defecation frequency were made. Statistical analysis for comparing the two groups were independent t-test and multivariate analysis (Cox regression). Statistical significant was defined ifF< 0.05 with 95% confidence interval.Results The mean duration of diarrhea in lactose-free formulagroup was 57.59 hours (SD 9.40) and lactose-containing formulawas 85.97 hours (SD 13.94), mean difference was 28.38 hours(SE 3.09) [P = 0.001; (95% CI 22.19 to 34.56)]. Decrease instool frequency was found significantly in the lactose-free formula group. Multivariate analysis (Cox regression) revealed that the intervention was affected significantly.Conclusion Lactose-free formula may shorten the duration of acute rotavirus diarrhea.
Thyroxine and thyroid stimulating hormone levels in under-five severe malnourished children Shelvi H. Tamzil; Ryadi Fadil; Diet S. Rustama; Melinda D. Nataprawira
Paediatrica Indonesiana Vol 43 No 2 (2003): March 2003
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi43.2.2003.42-5

Abstract

Background In Indonesia, protein energy malnutrition (PEM) inchildren is still a health problem. Malnourished children will havegrowth and development disruption, which is not only caused bynutritional factor, but might be associated with endocrine system,such as thyroid hormone metabolism. Hypothyroidism or thyroidhypofunction could be happened in malnourished children.Objective The purpose of this study was to assess thyroxine (T4)and thyroid stimulating hormone (TSH) levels in under-five severemalnourished children.Methods This was a descriptive study with cross sectional design.Subjects were all under-five severe malnourished childrenbased on nutritional evaluation in August 2001 done by local healthcare workers in Andir District, Bandung. Severe malnutrition wasdefined as weight for age less than -3SD (W/A <-3SD).Results There were 42 subjects who fulfilled inclusion criteria, aged11-57 months, five of them showed clinical manifestation of marasmus.The T4 levels of the 41 subjects were still in normal limitsand within the range of 4.5-11.2 mg/dl. Thirty-nine subjects hadnormal TSH levels, ranged from 0.9 to 5.0 mlU/ml, and 2 subjectsshowed increased TSH levels of 6.8 and 7.6 mlU/ml, respectively.Reduced T4 and TSH levels of 3.93 mg/dl and 0.2 mlU/ml, respectivelywere detected in one subjectConclusion In general, the T4 & TSH levels were still normal,with only one subject (2%) showed low levels of T4 & TSH.

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