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INDONESIA
Journal of Medicine and Health
Published by Universitas Kristen Maranatha
ISSN : 24425227     EISSN : -     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health
Journal of Medicine and Health (JMH) is an open access journal (OAJ), a periodic scientific publication biannually online published on February and August; using review and screening system by peer group reviewer. JMH receives original research articles which related to medicine, health, new developing therapy from traditional medicine or herbs and developing clinical therapy. JMH also receives otiginal review articles, case report, continuing medicine and health study. Articles should be written in good English or Indonesian language.
Arjuna Subject : -
Articles 264 Documents
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Analysis of Fibronectin and TGF-β1 Immunoexpression to Determination of Wound Vitality in Wistar Rats (Rattus norvegicus) Novita, Nita; Agustina, Hasrayati; Hernowo, Bethy S.; Hassan, Abdul H.
Journal of Medicine and Health Vol 1, No 1 (2015)
Publisher : Maranatha Christian University

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Abstract

Wound examination is indispensable in forensic practice. The scientific field of wound age determination has advanced progressively during recent years.The purpose of this study was to determine the differences of fibronectin and TGF-β1 expression in both antemortem and postmortem wounds. This study was an experimental with completely randomized design.  The skin wounds (vital and postmortem) were taken from fourty Wistar rats and divided into 10 groups of rats. Immunohistochemical staining was performed to determine the differences between antemortem and postmortem wounds. The result showed that in 30 minutes after antemortem wound infliction, all of samples showed weak reactivity for fibronectin and TGF-β1 (100%).  In first hour after wound infliction, 3 samples (75%) showed weakly positive and 1 sample (25%) strongly positive for fibronectin and TGF-β1.  In 2 hour after wound infliction, 1 sample (25%) showed weakly positive and 3 sample (75%) strongly positive for fibronectin and TGF-β1.  In 3 and 4 hour after wound infliction, all of samples strongly positive for fibronectin and TGF-β1.  In postmortem wound, all of samples showed negativity for fibronectin and TGF-β1. In conclusion, fibronectin and TGF-β1 may be useful in the determination of wound vitality. Keywords: wound, fibronectin, TGF-β1, vitality
A Case Report: Clozapine in Diabetic Patient with Bipolar Mood Disorder Vera, _; Sitha, Christine
Journal of Medicine and Health Vol 1, No 1 (2015)
Publisher : Maranatha Christian University

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Abstract

Depression and diabetes are often occur together and their morbidity has a significant impact of health outcomes. Antidepressants dan antipsychotics may cause metabolic abnormalities, as well as neurologic abnormalities. 52 years old diabetic woman presented to Immanuel Teaching Hospital with slurred speech. Since ten years ago, she had bipolar  mood  disorder, which was recently treated with clozapine. As patient consumed higher dose of clozapine (beyond her psychiatrist’s supervision), she had uncontrolled blood glucose level, fever, and slurred speech. The side effects of clozapine (weight gain, increased insulin resistance, dysarthria, fever) were discussed in this case report. During hospitalization, with strict supervision of clozapine use, the symptoms resolved. In diabetic patients with comorbid psychiatric disorders, a good collaboration between internist and psychiatrist is required to manage the patients effectively and comprehensively. Keywords: bipolar mood disorder, clozapine, diabetes mellitus, depression
NON MEDICAL FACTORS THAT AFFECT USAGE OF LONG ACTING REVERSIBLE CONTRACEPTIVE (LARC) IN WOMEN AFTER CHILDBIRTH IN INDONESIA Paskaria, Cindra
Journal of Medicine and Health Vol 1, No 2 (2015)
Publisher : Maranatha Christian University

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Abstract

The Long Acting Reversible Contraceptive ( LARC) is a method of contraception that is effective and efficient to prevent pregnancy or limit births, but its use in Indonesia is still low especially in women after childbirth.  This may increase the risk of unwanted pregnancy and short birth interval.  The purpose of this research is to find out what factors affect the use of LARC in women after childbirth in Indonesia. This research is an analysis of secondary data Indonesia Demographic and Health Survey 2012, with stamp 3,918 Women’s Reproductive Age, which is between 15-49 years  old and  they had given birth one year before the survey.  The data were analyzed by using simple logistic regression analysis.  This research shows that the proportion of women who used LARC after childbirth in Indonesia in 2012 was 7.31% and it was influenced by the level of socio-economic, domiciles, the husband’s level of education, the number of children born alive, the number of children still living, the desired number of children, the role of husband, and the role of religious figures. Keywords: LARC, women after childbirth, non medical factors
Peer Reviewers of JMH Volume 1 Number 2 Medicine and Health, Journal of
Journal of Medicine and Health Vol 1, No 2 (2015)
Publisher : Maranatha Christian University

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Abstract

We would like to thank our peer reviewers for the precious contributions in providing clinical,scientific, and methodological expertise for JMH Volume 1 Number 2. We appreciate everythoughtful review of submitted manuscripts and for making important contributions to improve thescientific quality of articles published in JMH. We listed the names in alphabetical order.Dr. dr Diana Krisanti Jasaputra, M.Kesdr. Djaja Rusmana, M.Si.Dra Endang Evacuasiany, M.S, AFKdr. Fenny, Sp.PKDr. dr. Hana Ratnawati, M.Kes., PA(K)Prof. Dr. Ida Parwati, dr, SpPK(K), PhDdr. Indra Sapta, Sp.THT-KLIngrid S. Surono, PhD.Dr. dr. Meilinah Hidayat, M.Kesdrg. Monica Irewaty Wibisana, M.Kes Sert Ortdr Sijani Prahastuti,M.Kesdrg.Susiana,Sp.OrtProf. Drs. Sutiman B.Sumitro,SU.,D.ScSylvia Soeng, dr., M.Kes., PA(K)Dr. Teresa Liliana W, S.Si., M.Kes., PA(K)Prof. dr. Wahyuni Lukita Atmadja, PhD.Dr. Yudi Mulyana H.,dr.,SpOG(K)
The Ethanol Extract of Neem Leaf (Azadirachta Indica A. Juss) Effect towards Wound Healing in Male Swiss Webster Mice Mustamu, Hillary L.; Evacuasiany, Endang; Liana, Laella K.
Journal of Medicine and Health Vol 1, No 3 (2016)
Publisher : Maranatha Christian University

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Abstract

accelerates wound healing. We examined the effect of Ethanol Extract of Neem Leaf (EENL) inaccelerating wound healing and compared its potential with povidone iodine. This was ananalytic experimental study, using Complete Randomized Design (CRD) with a comparativemethod. We used 30 male Swiss Webster mice that were divided into five groups (n=6). Eachgroup was given the Ethanol Extract of Neem Leaf (EENL) with a concentration of 25%, 12.5%and 25%, aquades (negative control) and povidone iodine 10% (comparison). The averagewound healing time of EENL 25%, EENL 12.5% , EENL 6.25% , povidone iodine and aquadeswere 11.2; 12.2;13.2;13.2;and 1.3 days respectively. The data was analized with one wayANOVA and showed a highly significant difference of p=0.000. Tukey HSD test showed thatEENL 25% and 12.5% had better potential than povidone iodine 10% and EENL 6.25% had thesame potential with povidone iodine 10%. This study concludes that ethanol extract of neem leafhas an effect in accelerating the duration of wound healing, with EENL 25% as the bestconcentration in accelerating the duration of wound healing.Keywords: neem leaf, Azadirachta indica A. Juss, wound healing, Swiss Webster mice
The New Perspective of Exercise as a Breast Cancer Therapy Wiharja, Alvin
Journal of Medicine and Health Vol 1, No 3 (2016)
Publisher : Maranatha Christian University

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Abstract

The prevalence of cancer increases each year, from 4.7‰ in 2007 to 5 ‰ in 2013. InWest Java, the prevalence of cancer is quite high at 1.0 ‰. Obesity becomes a risk factor forcancer. Exercise is aimed to solve the obesity problem, prevent and improve the cancer patientcondition, as well as improve the quality of life of cancer patients. Exercise plays a role in thetreatment of cancer patients. The potential benefits obtained during and after exercise areincrements of strength, speed, muscle mass, physical functions, range of motions, immunefunctions, the average completeness of chemotherapy, improved body shape, moods andconfidence. For patients diagnosed with breast cancer, exercise acts as a therapeutic to preventthe disease and its etiology factors (hormonal theory, the theory of immunity and inflammationtheory). Applying the proper exercise (frequency, intensity, type and time) in cancer patientswould improve the physical performance which is impaired due to cancer. Exercise canimprove levels of fitness, muscle strength, quality of life and fatigue in patients with cancersurvivors. Diagnosis and management of cancer can decrease the system performance organsand it would be upgrade by good exercise.Keywords: breast cancer,exercise
The Preventive Effect of Fig Leaves’s (Ficus carica L.) towards Colon Histopathological Feature and IL-6 Serum Level on Ulcerative Colitis Induced Mice Tiono, Hartini
Journal of Medicine and Health Vol 1, No 4 (2016)
Publisher : Maranatha Christian University

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Abstract

Ulcerative colitis is a chronic inflammatory disease mainly affects sigmoid colon and rectum. The inflammation process will activate NF-κB and leads to proinflamatory cytokine release such as Interleukin-6 (IL-6). Fig leaves contain a high level of flavonoid which can prevent NF-κB activation, and further inhibits IL-6 secretion. This research aims to see the preventive effect of methanolic extract of fig leaves towards colon histopathological feature and IL-6 serum level on ulcerative colitis induced mice. Balb/C male mice were randomly assigned into 5 groups (n=5). The treatment groups were dextran suphate sodium (DSS) control group (group I), methanolic extract of Fig leaves dose 28 mg/ day control group (group II), and methanolic extract of Fig leaves dose 7 mg/ day (group III), 14 mg/ day (group IV), and 28 mg/ day (group V) for 14 days, which at the 8th till 14th day were given DSS to induce colitis. The results showed that both of colon mucosal damage and IL-6 serum level of group I were significantly different from other groups (p=0,029). In  conclusion, the methanolic extract of Fig leaves can improve colon mucous damage and decrease IL-6 serum level on ulcerative colitis-induced mice. Keywords: ulcerative colitis, fig leaves, colon mucousal damage, interleukin-6
Effect of Chewing Xylitol Gum on Salivary Volume and Acidity Angwarmase, Alfonsa; Tih, Fen; Hidayat, Meilinah
Journal of Medicine and Health Vol. 1 No. 5 (2017)
Publisher : Universitas Kristen Maranatha

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Abstract

Dental caries or tooth decay is a result of the production of acid from fermentation ofbacteria that destroy tooth tissue. It can be prevented by maintaining the stability of salivaryvolume and acidity. Chewing xylitol gum is beneficial for increasing salivary volume andacidity. The aim of the study is to determine the effect of chewing xylitol gum on salivary volumeand acidity. The study is a quasi experiment conducted to 30 males aged between 17-25 yearsold. Pre and post treatment’s salivary volume are measured with measuring cup. Pre and posttreatment’s salivary acidity are measured using a pHmeter with 0,1 accuracy. Data areanalyzed with paired “t” test (a = 0,05). Average salivary volume after chewing xylitol gumincreased very significantly from 0,26 mL to 13,37mL (p=0,000). Average salivary acidity afterchewing xylitol gum increased very significantyly from 6,47 to 7,36(p=0,000). The researchconcludes that chewing xylitol gum increases salivary volume and acidity.Keywords : dental caries, xylitol, salivary volume, salivary acidity
Factors Related to Cognitive Function in Elderly People Fransiska YD Mardiyanto; Dedeh S Jahja; Yenni Limyati
Journal of Medicine and Health Vol. 1 No. 6 (2017)
Publisher : Universitas Kristen Maranatha

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Abstract

Each year in the world, especially in Indonesia, many elderly people exposed to higher risk of dementia due to an increased number of the elderly population and the incidence of mild cognitive impairment in the elderly. The aim of this study is to find out what factors are related with cognitive function in the elderly population. The study used analytic method with cross sectional study design. Subjects were 60 elderly people; male or female ≥ 60 years old. Data were analysed with Chi Square Test (α = 0.05). Cognitive function was measured by MMSE test. The result were found a significant relation between age and cognitive function ( p = 0.014), level of education and cognitive function (p value = 0.000), physical activity and cognitive function (p value = 0.003), cognitive activity and cognitive function (p value = 0.002), and social interaction and cognitive function (p value = 0.000). Gender variable did not have relation with cognitive function (p value = 0.343). This study conclude that there was a relation between age, education level, physical activity, cognitive activity and social interaction with cognitive function in the elderly population. There was no relation between gender and cognitive function in the elderly population.Keywords: cognitive function, cognitive impairment, elderly, MMSE
The Correlation between Fasting Blood Glucose Level with Infiltrated Axillary Limph Node Rate in Infiltrating Ductal Carcinoma of the Breast Thomas Aribowo; Widyanti Soewoto
Journal of Medicine and Health Vol. 1 No. 6 (2017)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (366.107 KB) | DOI: 10.28932/jmh.v1i6.552

Abstract

Cancer cell have been shown to extensively use glucose for proliferation, even at hypoxia environment. The consumption of glucose in a hypoxia environment induced HIF and VEGF, which play a role in cancer cell infiltration process . The objective of study is to determine the relationship between fasting blood glucose levels with the amount of infiltrated axillary lymph node in patients with infiltrating ductal carcinoma. This is an analytic observational study with cross sectional design. The data obtained were tested with chi-square test (α < 0.05). This study was conducted on 24 infiltrating ductal carcinoma patients. The results showed p value of 0.004, indicating there is a significant correlation between fasting blood glucose levels with the amount of infiltrated axillary lymph nodes. The correlation coefficient ( r) value was 0.505; indicating medium level correlation. As conclusion, there is a significant correlation between fasting blood glucose levels with the amount of infiltrated axillary lymph node in patients with infiltrating ductal carcinoma.Keywords: axillary lymph nodes, breast cancer, fasting blood glucose level, infiltrating ductal carcinoma

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