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Rachmat Kosman
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As-syifaa Jurnal Farmasi
Published by Universitas Muslim Indonesia
ISSN : 20854714     EISSN : 25029444     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 397 Documents
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KORELASI KADAR ASAM URAT DALAM DARAH DAN KRISTAL ASAM URAT DALAM URINE Naid, Tadjuddin; Mas'ud, Ita Ayuningsih; Haryono, Kus
Jurnal Ilmiah As-Syifaa Vol 6, No 1 (2014): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (190.372 KB) | DOI: 10.33096/jifa.v6i1.33

Abstract

The study had been done about the correlation test betweenblood uric acid level, and urine uric acid cristal. The objective of this study was to find the correlation betweenblood uric acid level, and urine uric acid cristal. This studywas an observational study with cross sectional approach using serum and urine samples were taken from patients who have met the criteria of the study sample. The samples number are36 that all of them analyzed with test blood uric acid, and urine uric acid cristal.The data of result was processed and analyzed with statistic test of correlation test. The results of study showed that there are correlation between blood uric acid level and urine urine uric acid, that the more uric acid cristal exrated viaurine will make to reduce blood uric acid level.
JAMUR ENDOSIOMBION SI BINTANG LAUT (Asterias forbesi ) SEBAGAI ALTERNATIF ANTIBAKTERI BARU PADA BAKTERI PENYEBAB INFEKSI SALURAN PENCERNAAN Rusli, Rusli; Fajri, Muh Danial; Sari, A. Sri Nila; Asmasari, Nur
Jurnal Ilmiah As-Syifaa Vol 8, No 2 (2016): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (146.858 KB) | DOI: 10.33096/jifa.v8i2.199

Abstract

Search of new antibacterial compounds, continuously carried out in line with the increasing number of new diseases emerging, ranging from infectious diseases, cancer and other dangerous diseases. Bioactive compounds can be obtained from several sources, including from plants, animals, microbes and marine organisms, one of which is a starfish, including the endosymbiont. The research of activity fungal isolates endosymbiont on the starfish Asterias forbesi types have been carried out in order to get a fungal isolates that have activity eradicate pathogenic bacteria, especially in the gastrointestinal tract. This research method is isolation of fungal endosymbionts on the sample starfish with Potato Dextrose Agar Chloramfenikol (PDAC) medium at room temperature for 3x24 hours. Endosymbiont fungal isolates was purified by the quadrant method, until pure fungal isolates obtained, then do the fermentation with Yeast Maltose Broth (MYB) medium on shaker at a speed of 200 rpm for 14x24 hours. The Results of fermentat continued antibacterial activity using agar diffusion method. The Results isolation of fungal endosymbiont on Starfish Asterias forbesi types obtained five (5) pure fungal isolates endosymbiont. From the results of fermentation obtained test results that indicate the antibacterial activity of fungal isolates endosymbiont on Starfish (Asterias forbesi) provide activity against Pseudomonas aeruginosa,  Eschericia coli, Salmonella thypi,  Shigella dysentriae, Staphylococcus auerus, and Vibrio cholerea bacterial. The conclusions in this study was isolate fungal endosymbionts IJBL FF-UMI 04 the most active inhibits all the bacterial test. Isolates with the greatest inhibit zone is isolate IJBL FF-UMI 03 on the test bacteria Salmonella thypi of 21.3 mm.
FORMULASI SEDIAAN MOUTHWASH DARI SARI BUAH SIRIH (Piper betle L.) VARIETAS SIRIBOAH Ririn, Ririn; Tandjung, Amran Ilyas; Wagola, Sarif
Jurnal Ilmiah As-Syifaa Vol 5, No 2 (2013): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (261.531 KB) | DOI: 10.33096/jifa.v5i2.56

Abstract

Piper betle fruit empirically is believed to maintain  oral health, but unfortunately the use of piper betle fruit not to be proven scientifically, therefore one of the efforts in explore benefits of betel fruit is to formulatedinto mouthwash. The aim of this research was to prepared stable and effective mouthwash preparation which is inhibit the growth of Streptococcus mutans. There were 3 formula designed  by varying the concentration of the piper betle fruit juice 3, 4 and 5 % v/v respectively. Stability evalution carried out before and after accelerated condition at 5oC and  35oC for 10 cycles in which the parameter  were organoleptic, pH value, viscosity and inhibitory  Streptococcus mutans of the bacteria. The assay results of the inhibition of each formula with agar diffusion method showed that the 3 formula were able to inhibit the growth of Streptococcus mutans, but the most optimum stability and effective inhibiting Streptococcus mutans was formula F3,that contain 5% fruit juice,  due to there was no significant change before and after accelerated condition. Key word : Mouthwash, Piper betle fruit (Piper betle L.), Streptococcus mutans
ANALISIS KADAR TIMBAL (Pb), SENG (Zn) DAN TEMBAGA (Cu) PADA IKAN BANDENG (Chanos chanos Forsk.) YANG BERASAL DARI LABBAKKANG KAB. PANGKEP SECARA SPEKTROFOTOMETRI SERAPAN ATOM (SSA) Zulfiah, Azizah; Seniwati, Seniwati; Sukmawati, Sukmawati
Jurnal Ilmiah As-Syifaa Vol 9, No 1 (2017): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (48.538 KB) | DOI: 10.33096/jifa.v9i1.257

Abstract

The research was done to analysis of amount lead (Pb), zinc (Zn) and copper (Cu) at milkfish (Chanos chanos Forsk.) from Labbakkang Pangkep by Atomic Absorbtion Spectrophotometry (AAS). Before to be analised, first to do destruction of milkfish (Chanos chanos Forsk.) later on HNO3. Quantitative analysis used atomic absorbtion spectrophotometry (AAS) at wave length of 283,3 nm for lead (Pb), 213,9 nm for zinc (Zn) and 324,8 nm for copper (Cu). Result of research find average rates of lead (Pb) and copper (Cu) from Labbakkang Pangkep is 0,0392 mg/kg and 0,0882 mg/kg. From result of research to showing that average rates Pb and Cu in the location, it is not over from still limit and according to Dirjen POM regulation.
PENENTUAN NILAI SPF (SUN PROTECTING FACTOR) EKSTRAK ETANOL JAMUR KANCING (Agaricus bisporus) SECARA IN VITRO DENGAN METODE SPEKTROFOTOMETRI UV-VIS Asriani Suhaenah; Masdiana Tahir; Nasra Nasra
As-Syifaa Jurnal Farmasi Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (380.156 KB) | DOI: 10.33096/jifa.v11i1.523

Abstract

Chronic exposure to ultraviolet light from the sun will cause changes in skin structure and oxidative stress on the skin. The effects can be in the form of acute changes such as erythema, pigmentation and photosensitivity, as well as long-term effects of premature aging and skin damage. Sun Protection Factor (SPF) is a universal indicator that explains the effectiveness of a product or substance that is UV protection. Natural ingredients that can be used as UV protection are button mushrooms (Agaricus bisporus). This study aims to determine UV light protection activity in the ethanol extract of button mushrooms (Agaricus bisporus) based on the SPF values analyzed by UV-Vis spectrophotometry at wavelengths of 290-320 nm. The results showed that at concentrations of 1% and 2% had a medium SPF category with SPF values of 17,762 and 28,643. For concentrations of 3% and 4% it has a high SPF category with SPF values of 30,592 and 31,325. The higher the concentration used, the better the SPF value.
PEMERIKSAAN FARMAKOGNOSTIK DAN SKRINING KOMPONEN KIMIA HERBA SURUHAN (Peperomia pellucida L.(Kunth).) ASAL KOTA MAKASSAR Asni Amin; Martati Martati
As-Syifaa Jurnal Farmasi Vol 1, No 1 (2009): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v1i1.88

Abstract

Peperomia pellucida  is  tradisional medicine used for treatment of hay fever, hipotensi, diuretic, and stomatichum in  Sulawesi Selatan, This research aimed to get data of morphology, anatomy and also data of physis and chemical from Suruhan for development of its for drug.  Sample extraction with methanoll 95%, physis data included content water soluble extractive 8,68%, dilute etanol soluble extractive 15,04 %, total ash  4 %, water insoluble ash  2,75%, acid insoluble ash  4,24%, identification by using chemical analysis to the powder of herb resulted alkaloid, steroid, tannin, lignin, pati, aleuron, and profil of TLC is steroid. Identification of morphology showed that Suruhan was Herb, wet bark, leaf simple, cordatus, strongly green, flowers are very small in dense spikes. Assay  anatomy to bark showed closed collateral vessel bundle, calsium oxalate crystal, transverse section of leaves indicated that epidermis with stomata type is anisositik, hypodermis, palisade, spons, vesicle bundle, and calsium oxalate crystal.Key Words : Identification, Piperomia pellucid
ANALISIS EFEKTIVITAS BIAYA PENGGUNAAN ANTIBIOTIK SIPROFLOKSASIN DAN SEFTRIAKSON PADA PASIEN INFEKSI SALURAN KEMIH RAWAT INAP DI RSU ANUTAPURA PALU TAHUN 2016-2017 Siti Atika; Ihwan Ihwan; Muhamad Rinaldhi Tandah
As-Syifaa Jurnal Farmasi Vol 10, No 2 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (333.531 KB) | DOI: 10.33096/jifa.v10i2.336

Abstract

Urinary tract infection is an infection that comes from bacteria and affects the top or bottom of the urinary tract. Effective treatment can be done  by choosing and using appropriate antibiotics. The principle of selecting  antibiotics is called cost effective. This  study aims to analyze the cost-effectiveness of using ciprofloxacin and ceftriaxone antibiotics in patients with urinary tract infection. The method used is  retrospectively quantitative. Data obtained from medical records, and medical payment in the form of direct medical costs of ciprofloxacin and ceftriaxone antibiotics on inpatient with urinary tract infection at General Hospital Anutapura in the period of 2016-2017. The results showed  the cost-effectiveness of antibiotics ceftriaxone is more cost effective than ciprofloxacin antibiotics with an ACER value of Rp12.249,5 and ICER value of Rp2.336,5. Based on the cost-effectiveness of antibiotics the results of chi-square test obtained p value = 0.157, it is concluded that there is no significant difference between ciprofloxacin and ceftriaxone.
PEMERIKSAAN FARMAKOGNOSTIK DAN PROFIL KROMATOGRAFI LAPIS TIPIS TUMBUHAN BAGORE (Caesalpinia crista Linn) ASAL DAERAH POLEWALI MANDAR SULAWESI BARAT Risda Waris
As-Syifaa Jurnal Farmasi Vol 3, No 1 (2011): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v3i1.120

Abstract

Pharmacognostic assay and using thin layer chromatography of Bagore plant (Caesalpinia crista, Linn).The morphology showed Bagore was the dycotiledonae with woody bark. Transverse section leaves indicated there are stomata anisositik. Transverse section of bark  showed open kolateral.                Physic measurement was including total ash level measurement 6,24 % and undissolved acid ass level equal to 0,55 %. Ekstraction level measurement which included dissolved water extraction level 73,69 % and dissolved etanol ectraction level equals 36,24 %. It was countaining steroid compounds.                Thin layer chromatography result with specific reagent that is on Lieberman-Bouchard reagent after sprayed showed violet this showed positifely countaining steroid compound groupKey word : Bagore(Caesalpinia crista Linn), identification, juice content, ash level.
Antibacterial Activity Assay Of Ethanolic Extract Of Bulbs Sticky Taro (Colocasia esculenta) Use TLC-Bioautografi Hibai, Achmad Rosyadi Yusuf; Herwin, Herwin; Kosman, Rachmat
Jurnal Ilmiah As-Syifaa Vol 7, No 1 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (156.96 KB) | DOI: 10.33096/jifa.v7i1.24

Abstract

A research on antibacterial activity assay of sticky ethanolic extract from taro tuber (Colocasia esculenta) has been conducted in order to determine the antibacterial activity of ethanolic extract of the stem Colocasia esculenta against several assay bacteria use TLC-Bioautografi. Results of antibacterial activity screening showed that the ethanol extract of te Colocasia esculenta at a concentration of 1 mg/ml exhibited inhibitory activity against bacteria of Bacillus subtilis, Escherichia coli, Pseudomonas aerugginosa, Salmonella typhi, Shigella dysentriae, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mutans, and Vibrio cholera. Test result showed by TLC-Bioautography using the eluent n-hexane : ethyl acetate (4:1) obtained Rf 0.38 value providing activity to Escherichia coli, Pseudomonas aerugginosa, Salmonella typhi, Shigella dysentriae, Staphylococcus aureus, Streptococcus mutans, and Vibrio cholera. The results of identification of active chemical component showed that the ethanolic extract of the stem of Colocasia esculenta on Rf 0.38 value was te alkaloid using dragendorf as the reagent.
FORMULASI DAN UJI EFEKTIVITAS GEL DAN SALEP MINYAK KEMANGI (Ocimum basilicum Linn) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS Ririn, Ririn; Zulkarnain, Iskandar; Natsir, Siska
Jurnal Ilmiah As-Syifaa Vol 8, No 1 (2016): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (221.995 KB) | DOI: 10.33096/jifa.v8i1.163

Abstract

Basil is one of a plant that has antibacterial activity on Staphylococcus aureus, the cause of furuncle. To cure the desease it is require preparations with a good penetrability, i.e gels and ointments. The goal of the research was to obtained the most stable both gel and ointment formulations of basil seed oil (Ocimum basilicum Linn.) pharmaceutically and effective microbiologically. Physical stability evaluations were performed by the parameters were organoleptic, viscosity measurement, homogeneity, spreadability, and flowing type at 5oC and 35oC for 12 hours on each temperature for 10 cycles. Organoleptic assay showed that there was no change in color, odor and concistency of all formula. Based on statistic analyses by Randomized design exhibited a significant change of gel and ointment formulation during storage. Homogeneity test showed that all formula possess even particle distribution. Based on rheogram exhibited thixotrophy-plastic flow type. Microbiological assay carried out by observe the formed inhibitory zone. Physical evaluation obtained formula II of gel was the most stable (12% basil seed oil) and formula III of ointment (18% basil seed oil) and microbiologically effective was formula III.  While the most effective microbiologically in inhibit the growth of Staphylococcus aureus was gel preparation in 18% concentration of basil seed oil.

Page 15 of 40 | Total Record : 397

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