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As-syifaa Jurnal Farmasi
Published by Universitas Muslim Indonesia
ISSN : 20854714     EISSN : 25029444     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 397 Documents
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FORMULASI YOGHURT SEBAGAI LOSIO PEMBERSIH WAJAH DENGAN MENGGUNAKAN VARIASI EMULGATOR Faradiba Faradiba; Nursiah Hasyim; Andi Fitriyati
As-Syifaa Jurnal Farmasi Vol 2, No 1 (2010): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v2i1.106

Abstract

Yoghurt formulation as facial cleansing lotion has been done in which the emulsifier were nonionic (tween 60 and span 60), amine soap (triethanolamin and stearic acid), and detergent (sodium lauryl sulfate) respectively. The aim was to determine the most optimum stabilty formulation. The evaluation was carried out before and after accelerated condition in 5ºC and 35ºC respectively for 10 cycles.Organoleptic, creaming volume, emulsion type, dirpersed globul, viscosity, and yield value were observed. The result of organoleptik showed that there were no change in color and smell, creaming volume and dispersed globul before and after accelerated condition. Statystic analyses foward the viscosity in formula I was apparently indifferent mean while the second and the third formula were different in viscosity. statystic analyses foward the yield value in formula I was apparently indifferent and the second  was different mean while  the third formula very different in yield value. Formula I showed the most minimum alteration in rheogram . Of it the has taken that the most stable emulsion was nonionic emulsifier (tween 60 and span 60).Key Words : Facial cleansing lotion, Yoghurt, Emulgator
UJI EFEK ANTIINFLAMASI FRAKSI KLOROFORM DAUN JOHAR (Cassia siamea Lamk.) DENGAN METODE RAT HIND PAW EDEMA Sitti Amirah; Hendra Herman
As-Syifaa Jurnal Farmasi Vol 7, No 2 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (316.391 KB) | DOI: 10.33096/jifa.v7i2.10

Abstract

Johar (Cassia siamea Lamk.) leaves widely used as a traditional medicine. Johar leaves contain chemical compounds such us alkaloids, tannins, saponins, flavonoids, sitosterol and barakol which have effect of treatment for several diseases including inflammatory. This study aims to determine anti-inflammatory effect of chloroform fraction C.siamea leaves. This study was conducted using 15 Wistar rats were divided into 5 groups: control group who were given suspension of Na.CMC 1% w / v, the comparison group were given diclofenac sodium suspension 0.35 mg / kg, the test group dose of 75 mg / kg, the test group dose of 150 mg / kg and a test group of 300 mg / kg. Evaluation of anti-inflammatory activity was done by measured initial volume of the foot all test animal then given the drug orally according to dosage of its group. After 30 minutes, each group made inflammatory by induced karagen 1% 0.1 mL by intraplatar. Furthermore, inflammation’s degrees was measured every hour for 8 hours. The results obtained show that after 2 hours, inflammatory of the control group Na.CMC had increased much higher compared to the other groups. This is shows that Na.CMC doesn’t have effects anti-inflammation. The comparison group diclofenac sodium gave the best inhibitory effect that have been shown from an increase volume of feet smaller than the test group chloroform fraction of Johar leaves. While in chloroform fraction of Johar leaves test group, group with dosage 75 mg/kg gave an inhibitory effect better than the other test group dosage.
UJI EFEK ANTIINFLAMASI EKSTRAK ETANOL DAUN SIRSAK (Annona muricata Linn.) TERHADAP MENCIT (Mus musculus) JANTAN YANG DIINDUKSI DENGAN KARAGEN Rahmawati Rahmawati; Safriani Rahman; Mustari Mustari
As-Syifaa Jurnal Farmasi Vol 4, No 1 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (155.291 KB) | DOI: 10.33096/jifa.v4i1.138

Abstract

The research about aniinflammatory effect of Sirsak leaves (Annona muricata Linn.) ethanolic extract in male mice (Mus musculus) was conducted, the aim to assay the anti-inflammatory effect of Sirsak leaves done extract based on decrease in oedema volume of foot palm male mice. It was used 15 male mices that evaluated and divided into 5 groups that each group has 3 mices given extract in dose 0f 0,182 g/kgBB, 0,546 g/kgBB and 0,91 g/kgBB, one group as the compore which administered diclofenac sodium, one negative control group which administered 1% Na.CMC. induction carried out by injection 1% w/v carrageen 0,05 ml subcutan in the feet palm of mice. One hour later each group administered the teste preparation orally 1 ml/30 gBW. Group 1 to 3 the series dose of the extract 0,182 g/kgBB, 0,546 g/kgBB and 0,91 g/kgBB. Group 5 diclofenac sodium suspension. The measurement of oedema volume carried out prior and after administration of the tested preparation 0, 30, 60, 90, and 120 minutes. The data correlation between oedema versus time analysed value with use SPSS 20.Result indicated variaties with ethanolic Extract of Sirsak leaves have the effect antiinflamatory at dose 0,182 g/kgBB, 0,546 g/kgBB, dan 0,91 g/kgBB and not differ the reality by Natrium Diklofenak.Keywords : Inflamation, Anona muricata’s leaf, Carageen.
FORMULASI BUBUR INSTAN KOMBINASI TEMPE DAN RUMPUT LAUT SERTA EFEK SINERGISMENYA TERHADAP KOLESTEROL DARAH Syamsuri Syakri; Natsir Djide; Faisal Attamimi
As-Syifaa Jurnal Farmasi Vol 6, No 2 (2014): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (116.227 KB) | DOI: 10.33096/jifa.v6i2.48

Abstract

Formulation  of Instant Porridge as the combination of Tempe and seaweed and its Synergism Effect Of Cholesterol level Blood. The aim of the research is to make instant porridge as the combination of tempe and seaweed which could be used as a food alternative and its influence on patients cholesterol and the determine  a suitable formulation in making instant porridge as the combination of tempe and seaweed. The absorption was measured by using photometer 5010 with a long unbroken wave 546 nm. The statictical analysis reveal that instant porridge as the combination of tempe and seaweed could decrease cholesterol in which decrease of cholesterol really  differs among formulation 1,2, and 3. The one in formulation 2 is 50%, and the one formulation  3 is 40%. The effect of synergism occurs in formulation 2, i.e 50% in which the comparison of tempe and seaweed is 50  : 50. Hedonic test by 10 respondents proves that all the respondents like instant porridge as the combination of tempe and seaweed about colour, aroma, taste, and texture. Key word : Instant Porridge, Formulation, Cholesterol, Seaweed, Tempe
PRODUKSI SEDIAAN KOMBUCHA DARI DAUN PERMOT (Passiflora foetida L) SECARA FERMENTASI Herwin Herwin; Rachmat Kosman; Iswan Siami
As-Syifaa Jurnal Farmasi Vol 5, No 1 (2013): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (144.595 KB) | DOI: 10.33096/jifa.v5i1.65

Abstract

A research has been done about profit of permot leaves (Passiflora foetida L.) by using culture of kombucha with the aim to know the use of permot leaves (Passiflora foetida L.) as preparation of kombucha in a fermentation. Permot dried leaves boiled in 1000 ml water until boiling then got extract of permot. Extract of permot leaves added with 100 gram glucose and 10% of inoculum kombucha culture then fermented for 5 – 12 days. The results of kombucha preparation from permot leaves then testing with organoleptic, measuring pH and total acid test. Based of the results in preparation kombucha permot leaves (Passiflora foetida L.) showed that the  color-test organoleptic with hedonic method was obtained values 2.5, flavor 1.9, and taste 2.4. pH measurement before fermentation is 4 and after that is 3 with total acid of 0.66%. Key Word : Permot Leaves (Passiflora foetida L.), Fermentation, Kombucha of Preparation
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN ARBENAN (Duchesnea indica (Jacks.) Focke) DENGAN METODE DPPH Nuraziza Nuraziza; Seniwati Dali; Risda Waris
As-Syifaa Jurnal Farmasi Vol 9, No 2 (2017): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (290.007 KB) | DOI: 10.33096/jifa.v9i2.303

Abstract

Arbenan (Duchesnea indica (Jacks.) Focke) is a plant belonging to Rosaceae family which server as an antioxidant, flavonoids. This research aimed to determine the antioxidant activity of ethanol extract of arbenan leaves using DPPH. The leaves were extracted using maceration method with a sample size of 300 gs dissolved using ethanol 70%, then obtained the viscous extract of 32,49 gs. The arrest of free radicals for each tested sample under the inhibition of DPPH. The tests were conducted at the 4 concentration series of 10, 20, 30, and 40 ppm by using methanol p.a by the addition of 0,5 mL with 3,5 mL DPPH of 30 ppm. Antioxidant activity absorbance was measured by a spectrophotometer at the wavelength of   515 nm and IC50 value was calculated based on the absorbance data. The calculations showed that the Arbenan leaves have a very strong antioxidant activity with IC50 value of 30,20 µg/mL.
ISOLASI FUNGI ENDOFIT KULIT BUAH MERAH (Pandanus conoideus Lam.) YANG BERPOTENSI SEBAGAI ANTIBAKTERI SECARA METODE KLT - BIOAUTOGRAFI Reza Ariyadi Deponda; Fitriana Fitriana; Siska Nuryanti; Herwin Herwin
As-Syifaa Jurnal Farmasi Vol 11, No 2 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (150.544 KB) | DOI: 10.33096/jifa.v11i2.583

Abstract

Red fruit (Pandanus conoideus Lam.) belongs to genus Pandanus. Red fruit oil has the activity as an antibacterial. The research aimed to obtain endophytic fungi isolates on the red fruit peel and assay the antibacterial activity by TLC-Bioautography. The research was experimentally conducted including the process of isolation of endophytic fungi, purification, macroscopic examination, screening for antibacterial activity against Staphylococcus aureus and Salmonella typhi, fermentation for 7, 14 and 21 days, separation and antibacterial assay by TLC-Bioautography against Staphylococcus aureus and Salmonella typhi, the isolate fermentate of endophytic fungi for 7 days showed an Rf value of 0.49 against Staphylococcus aureus and an 0.47 against Salmonella typhi. The isolate fermentate of endophytic fungi for 14 days showed an Rf value of 0.58 against Staphylococcus aureus and an 0.69 against Salmonella typhi. The isolate fermentate of endophytic fungi for 21 days showed an Rf value of 0.69 against Staphylococcus aureus and an 0.67 against Salmonella typhi. In conclusion, red fruit peel had endophytic fungi isolate with the potency as an antibacterial.
FORMULASI GEL MINYAK KAYU MANIS (Oleum Cinnamomi) SEBAGAI PEMBERSIH TANGAN MENGGUNAKAN VARIASI KONSENTRASI CARBOPOL Faradiba Faradiba; Ermina Pakki; Fanny Fardiyani
As-Syifaa Jurnal Farmasi Vol 1, No 2 (2009): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v1i2.97

Abstract

As investigation has been done on cinnamomi oil gel formulation as hand clean use carbopol gel bases. The aim of the investigation was to select the most stable formula if cinnamomi oil through stability evaluation which done by organoleptic observation, viscosity and yield value determination. It was made three formula with several different concentration carbopol in this investigation that are 0,3 %, 0,4 % and     0,5 %. Of the  result organoleptic observation there was no alternation before and after stress condition. Result statistic analyse on viscosity data shown that there was an influence of gel formula to viscosity before and after stress condition. At formula I and III shown that there was a  very real influence between of  before and after stress condition, while at formula II shown that there was no real influence. Result statistic analyse on yield value data shown that there was an influence of gel formula to yield value before and after stress condition. At formula I shown that there was a  real influence between of  before and after stress condition, at formula III shown that there was a  very real influence between of  before and after stress condition, while at formula II shown that there was no real influence. The conclution was formula II have the most optimal stability  use concentration of carbopol 0,4 %.Key Words : Oleum Cinnamomi, Hand Clean, Carbopol
ANALISIS PENGARUH BERWUDHU TERHADAP PERUBAHAN TEKANAN DARAH SESAAT Achmad Akbar Ramadhan; Mochammad Erwin Rachman
As-Syifaa Jurnal Farmasi Vol 7, No 2 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.894 KB) | DOI: 10.33096/jifa.v7i2.3

Abstract

The ablution is a very important Islamic teachings as a condition of validity of prayers, besides ablution provide a very important benefit to human health. Objective: To determine the effect of berwudhu to changes in blood pressure on high school students shortly Global Mandiri Al - Ashri Makassar. Methods: This study used a survey method that uses the analytic approach of Cross Sectional. The samples used were mostly high school students Global Mandiri Al - Ashri Makassar as many as 50 people. Results : The results showed a mean systolic blood pressure was 123.56 mmHg before her ablutions, then after berwudhu 122.28 mmHg. Mean diastolic blood pressure before berwudhu was 64.08 mmHg , and 62.32 mmHg after her ablutions, with kemanaknaan p > 0.005 ( p = 0.270 ). Conclusion : There is a change in blood pressure just before and after her ablutions, although it is not significant.
UJI AKTIVITAS ANTIRADIKAL BEBAS EKSTRAK DIETIL ETER DAUN SIRSAK (Annona muricata Linn.) ASAL KOTA MAKASSAR DENGAN METODE DPPH Sitti Amirah; Rahmawati Rahmawati; Andi Evi Wulandari Luspi
As-Syifaa Jurnal Farmasi Vol 3, No 2 (2011): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v3i2.129

Abstract

Has been on concerning test of activity radical scavenging of soursop leaves (Annonamuricata Linn.) extract of dietileter with DPPH method. This research aimed to know the level activity of free radical based on binding of DPPH free radicals of Soursop leaves (Annonamuricata Linn.).Extraction of soursop leaves (Annonamuricata Linn.) by macerate with methanol, methanol extract then is partition with dietileter.Than measured of quantitative by five concentration  50 ppm, 100 ppm, 200 ppm, 300 ppm and 400 ppm, the result of measured have done  with statistical method of regretion simple linier with average value of IC50 are 4980,4 ppm.  This potency explainextract activity is still very lowers than vitamin C and BHT with value of IC50 are 10,304 mg/ml dan 43,394 ppm.  Key Words :DPPH, Radical scavenging, Annonamuricata Linn. 

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