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Rachmat Kosman
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As-syifaa Jurnal Farmasi
Published by Universitas Muslim Indonesia
ISSN : 20854714     EISSN : 25029444     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 397 Documents
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ANALISIS KEPUASAN PELAYANAN OBAT PADA PASIEN DI PUSKESMAS BERSTANDAR ISO 9001:2008 DI DONGGALA KECAMATAN BANAWA Sri Ayu Noviyanti; Alwiyah Mukaddas; Muhamad Rinaldhi Tandah
As-Syifaa Jurnal Farmasi Vol 9, No 2 (2017): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (174.857 KB) | DOI: 10.33096/jifa.v9i2.260

Abstract

Community health center is technical implementation unit of a district / municipality health service who are responsible for organizing health development in a working area. The aims of this study is to determine the relationship between drug services with the level of patient satisfaction at the pharmacy unit of Donggala community health center in Banawa subdistrict, and also to know the level of  patient satisfaction and expectations by measuring with Importance Performance Analysis method to the five dimensions of service in the pharmacy unit at Donggala community health center of Banawa subdistrict. This research was conducted at the pharmacy unit of Donggala community health center in Banawa subdistrict on September 2016 until December 2016 by purposive sampling using questionnaire as instrument through Likert scale. Patient satisfaction are measured using 5 dimension of service which are tangible, relibility, responsiveness, assurance and empathy were analyzed by Importance Performance Analysis (IPA). As the result with 151 respondents at the average of gap (GAP) is -0.82 and 80.87% match rate and the most widely indicator were mapped by cartesius diagram is in quadrant A which are the quality service must still be considered and improved. This is also shows patient in Donggala community health center are still less satisfied and their expectation are still below.
FORMULASI DAN UJI STABILITAS FISIK SEDIAAN EMULSI MINYAK IKAN LEMURU (Sardinella lemuru) Patihul Husni; Yasarah Hisprastin; Melinda Januarti
As-Syifaa Jurnal Farmasi Vol 11, No 2 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (259.546 KB) | DOI: 10.33096/jifa.v11i2.575

Abstract

Lemuru fish (Sardinella lemuru), a small type of pelagic fish, is often found in Indonesia. Lemuru fish oil contains high omega-3 which is benecficial for health. One effort that can be done to optimize the benefits of lemuru fish oil is formulated as an emulsion dosage form. The purpose of this study was to determine the formula and physical stability of the lemuru fish oil emulsion. The method in this study included preparation of emulsions with varian concentration of fish oil (F1: 5%, F2: 10%, and F3: 15%) using natural emulgators (gummi arabicum) and physical stability tests carried out at two temperature variations, 25oC and 40oC for 30 days. Physical stability tests included organoleptic, homogeneity, emulsion type, viscosity, pH, and the size of the average globule. The organoleptic test results showed that the three formulas showed phase separation at different time points at both the storage temperatures. The viscosity test results showed that the viscosity of the three formulas has decreased during the storage period. In the emulsion type test it was shown that all three formulas had an oil-in-water (O/W) emulsion type. The pH test results indicated fluctuations during the storage period. The average globul size test results showed that the F3 emulsion formula has a larger average globule size than F1 and F2. In conclusion, the most stable formula was F3 that containing 15% fish oil. F3 was stable for more than 21 days at 25oC and more than 14 days at 40oC.
FORMULASI EKSTRAK ETANOL DAUN SALAM (Eugenia polyanthum Weight) DALAM SEDIAAN GRANUL EFFERVESCENT A. Muflihunna
As-Syifaa Jurnal Farmasi Vol 1, No 2 (2009): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v1i2.96

Abstract

A research of effervescent granule has been done of ethanol extract of eugenia leaf in variation of acid and carbonate sources as well as lactose as the adsorbent. The ratio between extract and lactose were 1 : 0,5, 1 : 1 and 1 : 2 resepectively in formula A, B, C. This aim was determine the best pharmaceutic properties of granule. The evaluation carried out by organoleptic, lost of drying, angle of repose, flowbility, porosity, and dispersibility analyse by block random design showed that formula (has the lowest lost of drying than formula B and A). Formula C has the highest flowbility. Mean while in dispersibility exhibited formula C was the slowest one. Conclusion that might be draw that formula C in ratio 1 : 2 has  the best pharmaceutics properties.Key words : Eugenia polyanthum Weight, effervescent, formulation
EFEK ANALGETIK KOMBINASI EKSTRAK BUAH BELIMBING WULUH (Averrhoa bilimbi L) DAN EKSTRAK DAUN PEPAYA (Carica Papaya L.) PADA MENCIT (Mus musculus) Amran Nur
As-Syifaa Jurnal Farmasi Vol 10, No 2 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (154.971 KB) | DOI: 10.33096/jifa.v10i2.430

Abstract

Starfruit fruit (Averrhoa bilimbi L.) and papaya (Carica papaya L.) containing the same are flavonoids which have activity as an analgesic. Flavonoids in both plants are thought to function as analgesics because they can inhibit prostrglandin synthesis which results in no release of pain meditors. The purpose of this study was to determine the analgesic effect on extract of starfruit fruit, papaya leaf extract , and a combination of both. starfruit fruit and papaya leaves macerated using 70% ethanol. Examining the analgesic activity of both extracts and combinations using a dose of 500 mg / kg BB. If the weight of the mice is 20 g/BB then the dose variation is 1 mg / 20 g BB. For the combination of the two extracts, it was made a comparison of extracts of starfruit fruit : papaya leaf extract 1: 3, 2: 2, and 1: 3. The first group was given CMC N a 0.5% as a negative control, the second group was given mefenamic acid as a positive control, the group was then given extract test solution as an extract control. After 30 minutes, 1 % acetic acid-inducing induction was given then observed mice stretching. The results showed that the fruit extract inasi komb starfruit: papaya leaf extract 1: 3 has the most excellent analgesic activity diba nding extract activity alone or in combination other.
UJI TOKSISITAS EKSTRAK ETANOL BUAH MERAH (Pandanus conoideus Lam) ASAL MANOKWARI PAPUA BARAT DENGAN METODE BRINE SHRIMP LETHALITY TEST Safriani Rahman; Riyan Wulansari Puspa Seruni
As-Syifaa Jurnal Farmasi Vol 3, No 2 (2011): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (281.402 KB) | DOI: 10.33096/jifa.v3i2.128

Abstract

A research on Toxicity assay of Extract Ethanol  Red Fruit (Pandanus conoideus Lam) upon Brine Shrimp Lethality Test which intended to know the toxic effect of Red Fruit and supposed to determine Lc50 of the Red fruit by method Brine Shrimp Lethality Test. The ethanol ekstrak, was made in various concentration 10, 100, 1000 µg/ml. Mean while, for negative control was seawater which made by the same concentration. In each concentration has put in 10 brine shrimp. Each concentration has put 1 drop of yeast extract as source of food. The volume is added to 10 ml, observation is done after 24 hours treatment. Observation result in dead brine shrimp data. From the counted of probit analysis method obtained Lc50 value was that  52,844 ± 25,679 µg/ml. Mean while in negative compare there were not brine shrimp killed. Key words : Pandanus conoideus Lam, Brine Shrimp Lethality Test, Toxicity assay
ANALISIS METODE SEROLOGI WIDAL LAPANGAN, WIDAL PEMBANDING, DAN KULTUR PADA PENDERITA SUSPEK DEMAM TIFOID DI SULAWESI SELATAN Syamsu Rijal
As-Syifaa Jurnal Farmasi Vol 6, No 1 (2014): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (131.49 KB) | DOI: 10.33096/jifa.v6i1.32

Abstract

The aim of the study was to discover the difference of field widal and comparative widal in detecting Salmonella typhi in typhoid suspect patient, sensitivity, specificity, positive and negative prediction scores of Widal and to culture. The study was conducted at the Biomolecular and Immunology Laboratory of the faculty of Medicine Hasanuddin University. The number of samples was 40 typhoid suspect patiens colleted from examination of field Widal at public health centers and hospitals in south Sulawesi. The serum samples of the patient were reexamined by using Widal comparative methods, and culture examination was done to blood sample. The results of the study indicate that comparative widal sensitivity 70%, spesificity 26%, positive predictive score 24,1%, negative predictive score 16,7%, and filed Widal sensitivity 30%, specificity 30%, positive predictive score 16,7%, and negative predictive score 68,2%. The comparative Widal has higher sensitivity than field Widal.
IDENTIFIKASI PENGGUNAAN OBAT PADA PASIEN DIABETES MELLITUS TIPE II USIA LANJUT DENGAN BEER’S CRITERIA DI INSTALASI RAWAT INAP RUMAH SAKIT IBNU SINA MAKASSAR PERIODE TAHUN 2012 Rizqi Nur Azizah; A. Hudayah
As-Syifaa Jurnal Farmasi Vol 8, No 1 (2016): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (299.416 KB) | DOI: 10.33096/jifa.v8i1.168

Abstract

Using identification in the use medicine  with Beer's Criteria to the advanced age patients in Inpatient installation in Ibnu Sina Makassar Hospital which aims to observe, report, and identify in the use medicine  in elderly patient of Type II Diabetes Mellitus are covered by Beer's Criteria in inpatient installation in Ibnu Sina Makassar Hospital period 2012. This is a descriptive research by collecting data retrospectively. The results of this research concluded in the use medicine  there are 8 types of  drugs covered by the Beer’s Criteria, they are alprazolam 14.28%, insulin 64.28%, gliburide (gluconic®) 1.19%, metoclopramide (sotatic®) 4.76%, Kal. Diklofenak (kataflam®) 1.19%, mefenamic acid 3.57%, meloxicam 2.38%, and ketorolak 8.33%.
PENELUSURAN MIKROORGANISME PENGHASIL ANTIBIOTIKA DARI LIMBAH AIR DANGKE KABUPATEN ENREKANG SULAWESI SELATAN Fitriana, Fitriana; Jurianti, Jurianti
Jurnal Ilmiah As-Syifaa Vol 5, No 2 (2013): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.079 KB) | DOI: 10.33096/jifa.v5i2.55

Abstract

Has been studied antibiotic-producing microbial isolation from waste water districs dangke enrekang. Preliminary studies carried out using the method of casting on medium Nutrient Agar (NA) and Potato Dextrosa Agar (PDA) with dilutions of 10-1 to 10-5. The results of four isolates of microbes are active in NA medium and four isolatesPDA medium, and then observed in macroscopic and microscopic. Furthermore, bacterial and fungal isolates was purified by the method of quadrants on each medim Nurien Agar (NA) and Potato Dextrosa Agar (PDA). To produce antibiotis from microbial fermentation performed using Yeast Maltose Broth medium (MYB). The results of testing the activity of an antibiotic fermentation with agar diffusion method. The results showed that the bacterial isolates I and II Salmonella typhi and is active againts Candida albicans. Bacterial isolates I, II, III, and IV, were active againts Staphylococcus epidermis, Streptococcus mutans, Pseudomonas aeruginosa, Vibrio sp, Escherichia coli, Bacillus subtilis and Staphylococcus aureus. I fungal isolates active against Salmonella typhi. II and IV of fungal isolates active against Pseudomonas aeruginosa. IV fungal isolates active against Vibriosp, Escherichiacoli and Stapylococcusaureus.Key word : Studied Antibiotic-Producing, Waste Water, Dangke, Enrekang
Efek Pemberian Minyak Zaitun (Olive oil) Terhadap Perubahan Profil Lipid Pada Tikus putih (Rattus novergicus) Syamsu, Rachmat Faisal
Jurnal Ilmiah As-Syifaa Vol 9, No 1 (2017): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.174 KB) | DOI: 10.33096/jifa.v9i1.236

Abstract

This research aims to know  the effects of olive oil  to changes profil lipid (total cholesterol, LDL, HDL, and triglycerides)  in the blood of the Rattus novergicus who were given a  high cholesterol diet. This research is experimental research methods laboratory with pre and post test control . Homogeneous data and normal data  next performed a test of paired t-Test and LSD test.  All test data using the 95% significance level (p = 0.05).  Conclusion of this research is the olive oil was able to lower the lipid profile, cholesterol 22,61%, LDL 38,48%, triglycerides 17.61% and increase the HDL 25.32%  in the blood of rats high cholesterol diet
UJI EFEK EPITELISASI EKSTRAK DAUN EKOR NAGA (Rhaphidophora pinnata (L.f) Schott.) PADA TIKUS Safriani Rahman; Andi Maulana Kamri
As-Syifaa Jurnal Farmasi Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (160.498 KB) | DOI: 10.33096/jifa.v11i1.516

Abstract

Burns are damage to the skin due to contact with sources of heat and radiation. The stage of handling burns involves several phases, namely the inflammatory phase, proliferation and maturation.  This study aims to determine the effect of epithelialization of ethanol extract of dragon tail leaves (Rhaphidophora pinnata (L.f) Schott.) In the process of wound healing. This research was conducted in an experimental laboratory and used rat test animals. 15 animals were divided into 5 groups consisting of group I (control) given Na.CMC, group II were given bioplacenton ointment, group III, IV and V (group given) giving ethanol leaves Rhaphidophora pinnata extract. Giving is done twice a day for 14 days. The wound is made by inducing the back of a mouse with a hot plate of 100o C for 2 seconds.. The results of the study data are the average wound diameter and percent of wound reduction in statistics using oneway ANOVA and LSD follow-up test. Based on the results of the research that has been done, it can be concluded that the ethanol extract of dragon tail leaves  has the effect of epithelialization in rats.

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