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Rachmat Kosman
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As-syifaa Jurnal Farmasi
Published by Universitas Muslim Indonesia
ISSN : 20854714     EISSN : 25029444     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 397 Documents
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ISOLASI DAN IDENTIFIKASI GOLONGAN SENYAWA KIMIA FRAKSI DIETIL ETER DAUN BERUWAS LAUT (Scaevola taccada (Gaertn.) Roxb.) ASAL KABUPATEN PINRANG (SULAWESI SELATAN) Kosman, Rachmat; Tappang, Kurniati
Jurnal Ilmiah As-Syifaa Vol 4, No 2 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (108.129 KB) | DOI: 10.33096/jifa.v4i2.87

Abstract

Isolation and identification of the chemical compound diethyl ether was done at beruwas laut leaves. Extraction is carried out using methanol and then partitioned with diethyl ether. Fraction of diethyl ether then isolated by column chromatography method using adsorben and n-hexane: ethyl acetate (3:7) as the elution fluid. Then obtained 30 fractions by color and by KLT profiles obtained 16 fractions. dominant fraction with patches further purified by preparative KLT to obtain the pure compound. Tape I at 366 nm UV rays were analyzed by ultraviolet-visible spectroscopy showed maximum absorption at a wavelength of 239.5 nm as measured from wavelength 200-800 nm. Whereas isolates infrared spectroscopic data allow hydroxy, aromatic, and alkyl ketones.Whereas chemical reactions showed positive flavanoid compounds.Key Words : Isolation and identification, fractions of diethyl ether, Scaevola taccada (Gaertn.) Roxb
HUBUNGAN LAMA PENGGUNAAN ALAT ORTODONTIK CEKAT TERHADAP AKUMULASI PLAK DAN pH SALIVA MAHASISWA FKG-UMI TAHUN 2017 Lestari, Nurasisa; Puspitasari, Yustisia; Masdar, Tri Audia
Jurnal Ilmiah As-Syifaa Vol 10, No 1 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (248.358 KB) | DOI: 10.33096/jifa.v10i1.410

Abstract

Orthodontic treatment is a form of treatment in the field of dentistry which plays an important role in improving dental structure. Fixed orthodontic tools have an important role to obtain optimal and harmonic occlusion. Orthodontic appliance also affects plaque accumulation and salivary pH so that it can cause various dental and oral diseases The purpose of this study was to determine the relationship between the length of fixed orthodontic use to plaque accumulation and salivary pH of FKG UMI students in 2017. This study was an analytic observational, cross sectional study method.The sample of this study was FKG UMI students who used fixed orthodontics, sampling techniques with total sampling.Statistical test used Independent Samples Test. The results of this study showed <12 months long fixed orthodontic use of 30.8% and> 12 months of 69.2%. Based on plaque accumulation the highest score was 74.4%. Based on salivary pH the highest score is acid 94.9%, and based on statistical tests obtained a significant value of p = 0.001 (<α = 0.05). The results showed that there was a correlation between the length of fixed orthodontic use of plaque accumulation and salivary pH of FKG-UMI students in 2017.
UJI SENSITIVITAS BEBERAPA ANTIBIOTIKA PADA JAMUR PENYEBAB KANDIDIASIS MULUT Herman, Hendra
Jurnal Ilmiah As-Syifaa Vol 3, No 1 (2011): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v3i1.119

Abstract

Has been done research Sensitivity Test of Several Antibiotic on  Candidiasis Mouth – Caused by mushroom. Kirby Bouer agar diffuse method used in this research, in which 15 specimen of acne were taken and performed three times replication to get a better result. Result of the research based on diameter of inhibitory zone showed that from three replication the antibiotic which sensitivity the most on   Candidiasis mouth – cause mushroom are Nystatin (60%), Griseofulvin (33,33%), Ketokenazol(26,67%), Flukonazol (26,67%) , Myconazol (6,67 %). The conclusion is antibiotic which sensitivity the most on Candidiasis mouth– caused by mushroom is Nystatin.   Key Words : Sensitivity Test, Antibiotic, Candidiasis Mouth.
UJI AKTIVITAS ANTIOKSIDAN KOMBINASI INFUSA BIJI ALPUKAT (Persea americana) DAN BIJI PEPAYA (Carica papaya L.) TERHADAP TIKUS PUTIH (Rattus norvegicus) DIABETES MELLITUS DENGAN PARAMETER MDA Rahman, Safriani; Kosman, Rachmat; Sudrianto, Sudrianto
Jurnal Ilmiah As-Syifaa Vol 7, No 1 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (188.707 KB) | DOI: 10.33096/jifa.v7i1.23

Abstract

This research aims to determine the concentration Infusa Seeds Avocado and papaya seeds effective leaves that have antioxidant activity to MDA levels in diabetic mellitus with rats was induced with alloxan. This research used 21 white rats were divided into 7 groups. All rats were induced by alloxan 110 mg/KgBB intraperitoneally. Group I as a normal control,group II was administered with Na.CMC as a negative control, group III avocado seed infusion of 10%, group IV papaya seed infusion of 10%, group V infusion combination of avocado seeds and papaya seeds 4%v/v, group IV infusion combination of avocado seeds and papaya seeds 6%v/v, group VII infusion combination of avocado seeds and papaya seeds 8%v/v. Administration were given orally for 14 days orally. Before treatment, all groups except the group I was induced with alloxan 110 mg/kgBB in intraperitonially. Measurement of MDA levels before and after administration of infusion. MDA levels as measured on a spectrophotometer 532 nm wavelength. MDA Assay performed with TBA method. The results showed that the combined infusion of avocado seeds and papaya seeds, concentrations of 4%v/v, 6%v/v, 8%v/v effective as an antioxidant.
FERMENTASI NATA DARI SARI BUAH KURMA (Phoenix dactylifera) TERHADAP BEBERAPA VARIASI KONSENTRASI STARTER Acetobacter xylinum Rumi, Amelia
Jurnal Ilmiah As-Syifaa Vol 8, No 1 (2016): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (127.031 KB) | DOI: 10.33096/jifa.v8i1.162

Abstract

It has conducted research on the utilization of kurma juice to several concentration variant starter Acetobacter xylinum, by measuring the thickness, weight, moisture content, ash content, and crude fiber content. Date palm juice which was added glacial acetic acid, potassium dihidrogen phosphate 600 mg, magnesium sulphate 600 mg, sugar 48 gram, and 6 gram of urea and incorporated into several containers of 100 ml and varied the volume of the starter 5 %, 10 %, and 20 % of 14x24 hours fermented in 37  temperature. Results showed the concentration of 5 % was obtained thickness 14 mm, weight 30,7 gram, 81,75 % moisture content, ash content 0,10 %, and 3,93 % crude fiber content, the concentration of 10 % obtained thickness 16 mm, weight 39,7 gram, 85,44% moisture content, ash content 0,11 %, and 4,5 % crude fiber content, the concentration of 20 % obtained thickness 15 mm, weight 32,5%, 82,65% moisture content, ash content 0,08 %, and 4,5 % crude fiber content.
ISOLASI DAN AKTIVITAS ANTIMIKROBA AKTINOMYCETES DARI TANAH KARST TAMAN WISATA BANTIMURUNG ASAL MAROS SULAWESI SELATAN Fhahri Mubarak; Herlina Rante; Natsir Djide
As-Syifaa Jurnal Farmasi Vol 9, No 1 (2017): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (549.166 KB) | DOI: 10.33096/jifa.v9i1.226

Abstract

The increasing number of deaths caused by infection encourage researchers conduct early stage in the search for new antibiotics to resolve the issue. This study aims to isolate microbes aktinomicetes contained in karst areas of Bantimurung-tourist park district South Sulawesi province to see the antimicrobial inhibitory activity. The initial stage to get new antibiotics, researcher isolated, identified, characterized and tested the antimicrobial activity of isolates to be studied. One of microbes widely studied to be taken of its active compound is aktinomycetes. The research phase is actinomycetes isolation, isolates purification, and testing isolates antagonistic  actinomycetes  to see  whether  there  is a power resistor formed. From the results obtained 8 isolates  actinomycetes isolation, but only 6 isolates that can be grown back properly. Six of isolates  actinomycetes obtained, tested antagonist was done to see  the activity of inhibitory  power. Two of active isolateswas  obtained  that have  inhibitory  against  several  microbes  that P. aeruginosa and S. aureus which is then coded isolates of K21 and K32.
PENENTUAN KADAR FENOLAT TOTAL DAN AKTIVITAS ANTIOKSIDAN DARI EKSTRAK DAUN DADAP MERAH (Erythrina fusca Lour) SECARA SPEKTROFOTOMETRI UV-Vis Wardi, Epi Supri; Zulkarni R, Zulkarni R; Nurdianti, Desy
Jurnal Ilmiah As-Syifaa Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (348.452 KB) | DOI: 10.33096/jifa.v11i1.501

Abstract

Determination of total phenolate and antioxidant activity of red leaf extract (Erythrina fusca Lour) was done by UV-Vis spectrophotometry. This study aims to determine the total phenolic content and antioxidant activity of hexane, ethyl acetate and ethanol extract. The extracts were prepared using a non-polar-maseration method with hexane, ethyl acetate and ethanol solvents. The results showed total phenolic concentration using the Folin-Ciocalteu method were 0.412 g/100 g in the hexane extract, 1.782 g/100 g in the ethyl acetate extract and 5.455 g/100 g in the ethanol extract. Antioxidant activity conducted by using FRAP method (Ferric Reducing Antioxidant Power) were obtained 0,682 mmol Fe (II)/100 g at hexane extract, 5,186 mmol Fe (II)/100 g at ethyl acetate extract and 10,591 mmol Fe (II)/100 g on the ethanol extract. The antioxidant activity of gallic acid as standard was 44.356 g mmol Fe (II)/100g.
STANDARISASI EKSTRAK DIETIL ETER HERBA Oxalis corniculata L. Herwin Herwin; Aminah Hamzah
As-Syifaa Jurnal Farmasi Vol 4, No 2 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (145.687 KB) | DOI: 10.33096/jifa.v4i2.78

Abstract

A research have been conducted about standarisation of  diethyl ether ekstrack Oxalis corniculata L. herb from West Sulawesi of Mamuju with a purpose standarisation of  diethyl ether ekstrack Oxalis corniculata L. based on specific and non specific parameter. On the way KLT-Bioautography diethyl ether ekstrack with Rf 0.47 value to give activity to Staphylococcus aureus, Streptococcus mutans, Staphylococcus epidermidis, Salmonella thypi, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Vibrio sp, and Candida albicans. Based on standarisation to result diethyl ether ekstrack obtained that specific parameter to organoleptic fixing ekstrac is green chocolate, typically smelling, bitter  feel, jell konsistance, dissolve compound rate of ethanol 95% counted 31.37%, dissolve compound rate of water counted 24.00% and non specific parameter to stipulating on water rate counted 16.66%, dusty rate counted 4.16%, sour insoluble dusty rate counted 0.41%, total determination of bacterium 10x102 koloni/g and total kapang 37x101koloni/g. Key word : Oxalis corniculata L. Herb, Standarisation of the Diethyl Ether Ekstrack, Antimicrobial 
EFEK ANTIINFLAMASI EKSTRAK ETANOL DAUN KAMBOJA (Plumeria rubra L.) PADA TIKUS PUTIH (Rattus norvegicus) Safriani Rahman; Aulia Wati; Ema Sukmawati
As-Syifaa Jurnal Farmasi Vol 10, No 1 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (155.994 KB) | DOI: 10.33096/jifa.v10i1.329

Abstract

Inflammation is a body protective response against tissue injury which can be characterizet by the formation of edema. Frangipani Leaves contain flavanoids, saponins and alkaloids. The flavanoid compound is considered to have a useful effect for healing edema. This research aimed to examine the effects of anti-inflamatory and determined the dose of ethanol extract of the frangipani leaves (Plumeria rubra L.) as an anti-inflammatory  in the rat. The test of anti-inflammatory effect was done by using the Rat Hind Paw Edema method in which test animals it used 15 rats divided into 5 groups: groups I (negative control)  was given Na.CMC 1% w/v, group II (positive control) was given diclofenac sodium, group III, IV and V were given the ethanol extract of the frangipani leaves successive doses of 166,6mg/kgBW, 222,2 mg/kgBW, and 277,7 mg/kgBW, all groups were orally administered. The tested animals were induced carrageenan 1% w/v in intraplantar 0,5 mL and were meansured their foot edema volume before performed before induction as the intial volume (Vo), after induction, and 1 hour after the administration of the dosage form for 5 hours with the intervals of 1 hours using the pletismometer. The research result data were proccessed statistically using on-wey anova. Based of the data analysis showed that the ethanol extract of the frangipani leaves have the activity as the anti-inflammatory and statistically, the assay extract group showed the result not significantly different (p>0,05) against the diclofenac sodium group and a dose of 277,7mg/kgBW possessed the best activity compared to a dose of 166,6mg/kgBW and 222,2mg/kgBW.
ISOLASI DAN KARAKTERISASI SENYAWA BIOAKTIF EKSTRAK DIETIL ETER DAUN MIANA (Coleus scutellarioides (L) Benth) YANG AKTIF TERHADAP BEBERAPA MIKROBA UJI Nurmaya Effendi
As-Syifaa Jurnal Farmasi Vol 2, No 2 (2010): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v2i2.110

Abstract

Has been conducted research Isolation and characterization of compounds Bioaktif Leaf Extract Diethyl Ether Miana (Coleus scutellarioides (L) Benth) is active against some microbes Test. Maceration extraction is done with diethyl ether. Diethyl ether extracts obtained isolated by method column chromatography with using silica gel as absorbent and hexane-ethyl acetate as dilution fluid, and obtained six fractions. Fraction III-9 was isolated by Preparatif Thin Layer Chromatography (KLTP) and obtained ten tapes.Isolates fraction III-9 identified by chemical reaction with ammonia vapor, aluminum chloride and boric citro, and showed a positive reaction to the flavonoid class of compounds. Data ultraviolet-visible spectroscopy showed a maximum wavelength of 420 nm, while the infrared spectroscopy showed the existence of functional groups - C = C -; - OH; - CH3; and - CH - alifatis and - CH - aromatic. Isolates fraction III-9 with KLT-bioautgraphy was active against  microbial testing Staphylococcus aureus, Candida albicans and Salmonella thyposaKey Words : Leaf Extract Diethyl Ether Miana, Maceration, KLT-Bioautography

Page 10 of 40 | Total Record : 397

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