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Berkala Ilmiah Kedokteran Duta Wacana
Published by Universitas Kristen Duta Wacana
ISSN : 24609684     EISSN : 24768863     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Berkala Ilmiah Kedokteran Duta Wacana is a Scientific Journal to publish medical research articles, and other scientific medical articles from Medical Faculty of Duta Wacana Christian University academic community and also receive articles from other resources with appropriate and related topics. The policies taken for the largest composition of articles are the results of research, but can also receive scientific articles in the form of literature review and case reports. To maintain the quality of writing, Berkala Ilmiah Kedokteran Duta Wacana also cooperate with other Medical Education Institutions, especially in the recruitment of reviewer partner to conduct a "review" of all incoming articles. Funding for publication is entirely sourced from the Faculty of Medicine and also from Duta Wacana Christian University.
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Articles 161 Documents
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A REVIEW OF KOMBUCHA ANTIOXIDANT EFFECTS ON ATHEROSCLEROSIS IN PRECLINICAL STUDIES Elizabeth; Sharone Amabel; Ardo Sanjaya; Julia Windi Gunadi; Diana Krisanti Jasaputra
Berkala Ilmiah Kedokteran Duta Wacana Vol. 8 No. 2 (2023): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v8i2.521

Abstract

Background Atherosclerosis is the leading cause of death among cardiovascular diseases in Indonesia, in which death is possible if uncontrolled. The prevalence of the disease may be prevented by consuming foods or drinks containing high levels of antioxidant such as kombucha. Exploration of kombucha properties as an antioxidant that will improve atherosclerosis could be obtained from preclinical studies. Objective To discuss the antioxidant effect of kombucha on atherosclerosis in preclinical studies. Method This study is a narrative review with literatures from 2013 to 2022. Result Kombucha is an antioxidant-rich beverage made from enzymes generated by the SCOBY bacteria, which are fermented in sweet tea for 7-14 days to achieve optimal quantities of polyphenols. In addition to the antioxidants in the blood, the effect will lower the levels of LDL, VLDL, triglycerides, and total cholesterol in the blood. Moreover, it can increase HDL in blood and inhibit lesion forming in the aorta. Conclusion Polyphenol in kombucha tea has an antiatherogenic effect that may prevent atherosclerosis in preclinical studies. Keywords: antioxidant, atherosclerosis, kombucha, polyphenol
THE CORRELATION OF ABO BLOOD TYPES AND COVID-19 SEVERITY IN BETHESDA HOSPITAL YOGYAKARTA Pranata, Korin Bagas; Probowati, Wiwiek; Wuryaningsih, Nining Sri
Berkala Ilmiah Kedokteran Duta Wacana Vol. 8 No. 2 (2023): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v8i2.588

Abstract

Background COVID-19 is caused by the SARS-CoV-2 virus. The most recent study showed that there was a possible correlation between ABO blood types and COVID-19 risk. However, some studies disproved the correlation. The contradiction indicated that the correlation between the two variables has not been established. Objective To find the correlation between ABO blood types and the severity of COVID-19.  Methods It applied an observational-analytic method with a retrospective cohort approach. It used secondary data from 2020-2021 in Bethesda Hospital Yogyakarta. Samples were taken using a consecutive sampling technique. The collected data were analyzed using SPSS 26. Univariate analysis was made using descriptive statistics. Sequentially, bivariate and multivariate analyses were made using chi-square, odds-ratio, relative-risk, and ordinal logistic regression analysis. Results There were 212 data. Blood type O got the biggest percentage (38.2%) with a sample of 81 individuals. There were 88 patients with severe symptoms (41.5%), 86 patients with moderate symptoms (40.6%), and 38 patients with mild symptoms (17.9%). The Chi-square analysis of ABO blood types and the severity of COVID-19 was 0.05 (?0.05). The blood type B had a 2.8 times higher probability of severe incidence (95% CI 0.618–12.16) than the non-B blood type. Meanwhile, blood type O had a 0.33 times lower probability of severe incidence (95% CI 0.618–12.16) than non-O blood type. Conclusion The ABO blood types correlated with COVID-19 severity. Blood type O became a protective factor, and blood type B is the risk factor for severe COVID-19. TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian     TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back
MANAGEMENT OF CROUP IN CHILDREN: A CASE REPORT Wenly Susanto; Novia Bella Rianto; Dewa Agung Ayu Sridharaswari
Berkala Ilmiah Kedokteran Duta Wacana Vol. 8 No. 2 (2023): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v8i2.615

Abstract

Background Croup is a viral respiratory disease in children that attacks the larynx and trachea causes obstruction or blockage of the upper respiratory tract which, if severe, can be life-threatening.  Diagnosis of respiratory tract infection in children requires keen clinical vigilance to understand the risk of airway obstruction and the possible need for prompt intervention. Clinical symptoms in croup usually fever, runny nose, painful swallowing, and mild cough. This condition can develop into a loud, hoarse and harsh cough. Recognition of signs and symptoms is very important to prevent morbidity and mortality. Objective To describe diagnosis and management of croup in children. Case Description  A 3-year-old boy, came to the emergency room with complaints of sudden shortness of breath this morning accompanied by fever and a barking cough. These complaints had been felt for 3 days before going to the hospital, but they can reduce on their own and according to the parents there were no danger signs for complaints in their children. Conclusion  Croup is a self-limited disease, but sometimes it tends to be severe and even fatal. Prompt and appropriate management can prevent or reduce the risk of croup morbidity and mortality in children .              
MATERNAL AGE INCREASES THE RISK OF DOWN SYNDROME: A CASE-CONTROL STUDY IN YOGYAKARTA, INDONESIA Zevanya, Evita; Indrarto, Wikan; Lestari, Dewi; Widagdo, The Maria Meiwati
Berkala Ilmiah Kedokteran Duta Wacana Vol. 9 No. 1 (2024): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v9i1.636

Abstract

Background: Down syndrome incidence increases year to year and ranks first in birth defect cases in Indonesia. Down syndrome birth may burden family physically, socially, economically, and emotionally. The most common risk factor associated to Down syndrome is maternal age. Objective: This research is conducted to understand the association between maternal age and parity as the risk factors of Down syndrome births. Methods: Analytical observation design with case-control approach is used in this study. Bivariate and multivariate analysis were calculated using Chi-Square and binary logistic regression test. Results: This research’s results showed significant association between maternal age as risk factor with the incidence of Down syndrome (p-value < 0.001) and no significant association between parity with the incidence of Down syndrome (p-value > 0.05) in Yogyakarta, Indonesia. Mothers aged ? 35 years have 18.82 greater risk to give birth Down syndrome baby compared to mothers aged < 35 years (OR=18.82). The mean of maternal age when birth Down Syndrome children was 35.1 years old. Biological ovarium aging hypothesis presumed cause higher probability of chromosomal segregation failure during oocyte meiosis. Advanced maternal age naturally causes biological ovarium aging. Biological ovarium aging may caused or influenced by hormonal imbalance, limited oocyte pool, oxidative stress, change of spontaneous abortus mechanism, and genetic abnormality or mutation. No significant association between parity with the incidence of Down Syndrome (p-value=0.0689). Conclusion: Mothers with age of 35 year or older are the only the risk factor for having child with Syndrome Down in this research, with 18.82 more greater risk than mothers under 35 years old. The mean of maternal age when birth Down Syndrome children was 35.1 years old.
UKRIDA HOSPITAL WORKERS STRESS PROFILE USE PERCEIVED STRESS SCALE AND HEART RATE VARIABILITY METHODS Ronald Winardi Kartika; Fira Sonia; Chrispian Mahmudi; Hartanto; Yosephin Sri Sutanti
Berkala Ilmiah Kedokteran Duta Wacana Vol. 8 No. 2 (2023): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v8i2.652

Abstract

Background Stress is a condition of unbalance the physical and mental states, unable to respond of stimulus situations, and the end cause stress responses. Stress is one of the fourth ranked diseases in the world that experience stress. The symptoms of stress are palpitations, headaches, high blood pressure, disturbed digestion, shortness of breath, and difficulty sleeping. The measuring of stress using the perceived stress scale questionnaire in which the questionnaire has ten questions and the results obtained can determine the level of stress. If stimulation from internal or external stress occurs, will affect the nervous system, a heart rate variability tool used to measure the level of stress. Objective The aims of this study are to determine the relationship between stress and heart rate variability, and stress levels based on gender and age. Methods The conducted study was with quantitative analysis methods using cross-sectional design on 262 data. Results Based on the results of this study, the majority were aged less than thirty-five years and there were more women than men. In addition, the results of the chi-square test showed no significant relationship between stress and heart rate variability because the results of significancy was 0,432. Conclusions Measurement of stress on UKRIDA Hospital workers has not shown a significant relationship between the stress questionnaire and heart rate variability. However, there was a tendency for the worker to experience stress accompanied with an increase of the sympathetic nervous system measured by the Heart Rate Variability methods.
CIPLUKAN’S ANTI-INFLAMMATORY EFFECTS: MECHANISMS UNCOVERED Prasetyo, Yacobus Christian; Purwanti, Noerlina
Berkala Ilmiah Kedokteran Duta Wacana Vol. 9 No. 1 (2024): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v9i1.656

Abstract

Background: Ciplukan (Physalis angulata Linn) is a native American plant widely distributed in tropical regions including Indonesia. This herb has been used as a traditional ingredient to treat inflammation as well as other diseases. Ciplukan’s anti-inflammatory effects are thought to be triggered by the active compounds in the various parts of the herb. Objective: This review aims to describe the herb’s anti-inflammatory effects and its mechanisms. Methods: PubMed and Google Scholar databases were searched for articles using Boolean operations with keywords related to Physalis angulata and inflammatory components. We included literature in English and Indonesian without limiting the publication time range. Results: Ciplukan has an anti-inflammatory effect by regulating inflammatory mediators, inhibiting immune signaling pathways, and the genes associated with the immune system.
CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION: HOW TO DIAGNOSE? A CASE REPORT Sidhi Laksono; Hillary Kusharsamita
Berkala Ilmiah Kedokteran Duta Wacana Vol. 8 No. 2 (2023): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v8i2.665

Abstract

Background Chronic thromboembolic pulmonary hypertension (CTEPH) is a pulmonary embolism (PE) complication that is a primary cause of pulmonary hypertension (PH) and may lead to right heart failure and significant mortality especially when left untreated. Although CTEPH is the only cause of PH that is curable without needing to resort to lung transplant, it is often misdiagnosed due to the absence of diagnostic instruments and the absence of specific presenting symptoms. This also complicates the process of distinguishing between acute thromboembolic disease and the acute embolic event worsening of undiscovered CTEPH. Objective A better understanding of CTEPH is crucial, therefore we discuss a diagnosis rare case of CTEPH. Case Description A 44-year-old man presenting with syncope and chest discomfort who had no previous episodes of acute PE. Conclusion Computed Tomography Pulmonary Angiography (CTPA) is a significant test for identifying CTPEH. Oral anticoagulants may provide patients with CTEPH a safe and beneficial life-long treatment.
CHARACTERISTICS OF ADVERSE EVENTS OF CORONAVIRUS DISEASE 2019 VACCINES FIRST, SECOND AND BOOSTER Wiwiek Probowati; Tejo Jayadi; Brenda Miriane Rustam
Berkala Ilmiah Kedokteran Duta Wacana Vol. 8 No. 2 (2023): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v8i2.721

Abstract

Background Coronavirus Disease 2019 (COVID-19)  was a new type of highly contagious disease that had a high risk of developing Acute Respiratory Distress Syndrome (ARDS). According to the World Health Organization (WHO), COVID-19 can be transmitted mainly through aerosol particles contiguous to another human in one meter. To cope with this pandemic, the government programmed vaccinations around the world, including in Indonesia. Objective This study provided new information about the description of the characteristics of adverse events following vaccination participation in vaccination COVID-19 first, second and booster doses. Method This descriptive research was conducted using a cross-sectional method. Subjects were populations with various characteristics at Bethesda Hospital, Bethesda Lempuyangwangi Hospital, and the Jawa Dayu Christian Church who had received the COVID-19 vaccine. The data were univariately presented as a distribution table using the IBM  SPSS - Statistical Program for Social Science Statistics 23. Result From 400 respondents, the most common types of vaccine received during the first dose were Sinovac, the second dose of Sinovac,  and the Moderna for booster dose. Conclusion The first dose was the same as the second dose. Most felt drowsiness 87.9%, swelling and pain at the injection site 77.9%, and weakness at 60.4%.   In phase 1 clinical research of the mRNA vaccine from Moderna, side effects occurred in more than 50% of vaccination participants in the form of fatigue, chills, headache, myalgia, and pain at the injection site, especially at higher doses.
GERMINATED BLACK RICE (GEMAR) FUNCTIONAL BEVERAGE POWDER: A POTENTIAL ANTIOXIDANT FOR MANAGING DIABETES MELLITUS Sudana Fatahillah Pasaribu; Putra Chandra; Reno Irwanto; Nisya Ayu Rachmawati; Ratna Sari Dinaryanti
Berkala Ilmiah Kedokteran Duta Wacana Vol. 8 No. 2 (2023): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v8i2.778

Abstract

Background Diabetes mellitus (DM) is a degenerative disease and a leading global cause of death, often linked to increased oxidative stress and free radicals. Prolonged DM can lead to various complications, including kidney issues, heart problems, vision impairment, and more. Dietary regulation is a recommended approach to managing DM. GEMAR beverage powder, derived from germinated black rice and mung bean, holds the potential as a source of antioxidants and is beneficial for individuals with DM due to its rich phytochemical content. Objective This study aims to determine the yield and antioxidant activity of GEMAR powder beverage as a therapy for DM. Methods This is a quantitative research study employing a true experimental design, which will be analyzed descriptively. The ingredients GEMAR beverage powder germinated black rice, germinated mung bean, tempeh, red spinach, skimmed milk, soy protein isolate, and maltodextrin. The GEMAR beverage powder production includes sorting, mixing, roasting, drying, milling, and filtration stages. The GEMAR beverage yield value was obtained by comparing the final powder weight and the initial powder weight. Analysis of the antioxidant activity of GEMAR beverage powder using the DPPH method. Results The yield of GEMAR beverage powder was 41,6% and the antioxidant activity of GEMAR powder beverage was 24,30±0,07%. Conclusion This study concluded that GEMAR beverage powder is a functional beverage that has antioxidant activity and has the potential to be used as a therapy for DM. Keywords: antioxidants; functional beverages; black rice; diabetes mellitus.
THE RELATIONSHIP BETWEEN SCREEN TIME AND EMOTIONAL QUOTIENT IN MEDICAL STUDENTS Justinus Putranto Agung Nugroho; Yanti Ivana Suryanto; Lucas Nando Nugraha; Anggitya Bayu Prakoso
Berkala Ilmiah Kedokteran Duta Wacana Vol. 8 No. 2 (2023): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v8i2.786

Abstract

Background The use of gadgets, especially smartphones, is common among college students. The duration of smartphone usage in a day can be seen through the screen time records. High screen time records indicate high smartphone usage. Excessive use of smartphones has the potential to disrupt social interaction. Emotional Quotient (EQ) is very important in supporting social interaction. Emotional Quotient is a person's ability to express his feelings appropriately and effectively. Objectives This research was conducted to know the relationship between screen time duration and EQ in college students. Methods This research is an analytic observational study with a cross-sectional approach. Respondents in this study were students who met the inclusion and exclusion criteria. They were recruited using the consecutive sampling method. The duration of the screen time is obtained from the default smartphone application. Emotional Quotient was measured with the Trait Emotional Intelligence Questionnaire-Short Form (TEIQue-SF) questionnaire. Results There were 90 respondents (male = 27 people; female = 63 people) with an average age of 19.4 + 0.69 years. Spearman's test showed a relationship between screen time duration and EQ (p<0.01; r=-0.97). Conclusions This study concludes that the duration of screen time is related to EQ, the higher the duration of screen time, the lower the EQ. Therefore, to prevent EQ deterioration, it is important to limit screen time.

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