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Prediksi Tinggi Badan Ditentukan dari Panjang Rentang Lengan dan Panjang Telapak Kaki Pada Mongoloid Feminina Khususnya Etnis Jawa Nur Mujaddidah Mochtar
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 2, No 2 (2018)
Publisher : Universitas Muhammadiyah Surabaya

Background: There are various circumstances where measurements are not actually possible, replacement parameters can be used to estimate body height. Many characteristics of body height measurement and how to measure it. These include anthropometric measurements that can be used for the identification of medicolegal-forensic processes. Body height in clinical medicine and in the field of scientific research can be easily estimated using various anthropometric parameters such as arm span, knee height, foot length and foot breadth, and others. The arm span and foot length has proved to be one of the most reliable predictors. This study was conducted to estimate of body height from arm span and foot length using the regression equation and to determine the correlation between the body height and arm span and foot length.Methods: This study was conducted at Universitas Muhammadiyah Surabaya with 182 Javanese female students. Stature, arm span and foot length measured directly using anthropometric technique and measuring tape. The data obtained were then analyzed with SPSS version 16. The regression equation was derived for the estimate of body height and the relationship between stature, arm span and foot length determined by the Pearson correlation. Results: We found that the mean body height of Javanese women was 1534,45 ± 47,623 mm, mean of arm span 1543,25 ± 60,468 mm and the mean of foot length 226,14 ± 9,586 mm. The correlation between stature and arm span was positive and significant (r = 0,715 , p <0,05). The correlation between stature and foot length was positive and significant (r = 0,726 , p <0,05). The correlation between stature and arm span and foot length was positive and significant (r = 0,798, p <0,05). Conclusion: Body height correlates well with the arm span and foot length so that it can be used as a reliable marker for high estimates using regression equations.

Autopsi Verbal pada Kasus Kematian Mendadak di Instalasi Kedokteran Forensik RSUD Dr. Soetomo pada 1 November 2017 - 30 November 2017 Ambarini Isa Pratiwi
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 2, No 2 (2018)
Publisher : Universitas Muhammadiyah Surabaya

ABSTRAKKematian mendadak biasanya terjadi pada orang-orang yang merasa sehat dan tidak memiliki keluhan sebelumnya. Sebab kematian pada kasus kematian mendadak perlu dikonfirmasi oleh dokter secara legal pada surat keterangan kematian. Dalam rangka menentukan sebab kematian kasus kematian mendadak harus melakukan autopsi. Namun, pelaksanaan autopsi pada kasus kematian mendadak sangat kecil. Berdasarkan data di Instalasi Kedokteran Forensik RSUD Dr. Soetomo periode 2014-2016, hanya sekitar 12% kasus kematian mendadak yang dilakukan autopsi. Autopsi verbal dikembangkan untuk menentukan sebab kematian jenazah tanpa autopsi. Penggunaan autopsi verbal diharapkan dapat digunakan untuk menentukan sebab kematian yang valid sehingga pencatatan kematian di rumah sakit akan semakin baik. Penelitian ini menggunakan desain deskriptif observasional berdasarkan data primer hasil wawancara kepada keluarga 20 sampel jenazah yang memenuhi kriteria inklusi dan eksklusi. Penelitian ini dilakukan pada jenazah kasus kematian mendadakdi Instalasi Kedokteran Forensik pada 1 November 2017 – 30 November 2017. Dari 20 jenazah kasus kematian mendadak, 75% jenazah merupakan jenazah laki-laki. Kejadian kematian mendadak didominasi kelompok usia 40-60 tahun (50%). Sebab kematian mendadak didominasi sebab kematian terkait sistem kardiovaskular (55%). Pada penelitian autopsi verbal pada kasus kematian mendadak, laki-laki mempunyai risiko lebih tinggi dibandingkan perempuan dan angka kejadian akan meningkat seiring bertambahnya usia. Penyebab kematian pada kasus kematian mendadak banyak ditemukan pada kematian terkait sistem kardiovaskular, sistem respiratori, sistem saraf pusat, sistem pencernaan dan SIDS.Kata kunci: Kematian mendadak, autopsi verbal, sebab kematian. ABSTRACTSudden death is common and usually happen to a people who are feeling healthy and having no symptom before. Any suspicions about the cause of sudden death are need to be confirmed by the doctor with the legal cause of death written in the letter of death. In order to confirm the cause of sudden death the doctor has to held an autopsy. Unluckily, there is only little number of an autopsy are held in the case of sudden death. Based on the data in Instalasi Kedokteran Forensik RSUD Dr. Soetomo, an autopsy are held only about 12% from all the case of sudden death in the periode 2014-2016. Autopsy verbal are developed in order to define the cause of death without an autopsy. The used of an autopsy verbal expected to define a valid cause of death therefore the death registration in the hospital will be good. This research used observasional descriptive study which use primary data collected from the interview records with the family of the dead body involving a sample of 20 dead body after considering the inclusion and exclusion criteria. The study was conducted in the dead body who were on sudden death case admitted to Instalasi Kedokteran Forensik from November, 1st 2017-November, 30st 2017. Out of 20 patients with sudden death case, 75% was male. The incidence of sudden death was dominated by 40-60 years age group (50%). The cause of the sudden death was dominated by the cardiovascular system (55%). In this study of the autopsy verbal on sudden death, males were more at risk than females where the incidence was increased by the increasing of the age. The cause of sudden death were mostly found in the cardiovascular system, followed by respiratory system, central nervous system, digestive system, and SIDS. Keywords: Sudden Death, Autopsy Verbal, Cause of death. Correspondence: Ambarini Isa Pratiwi, Jln. Serayu BH-12, Wisma Troposo, Waru, Sidoarjo Phone: 085785406614; E-mail: ambrnsprtw@gmail.com

Insomnia is not a Risk Factor for Impaired Cognitive Function in Elderly yudhiakuari sincihu; Nita Kurniawati
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 2, No 2 (2018)
Publisher : Universitas Muhammadiyah Surabaya

Background: Elderly are often considered as a burden because of their physical limitations. Reduced cognitive function is one of the important causes for this physical limitation. Quality of sleep used to be associated with changes in cognitive function. Methods: A comparative analytic research to assess insomnia as a risk factor for the incidence of cognitive function impairment in the elderly. A case control study in elderly community at the nursing home St.Yosef, Surabaya. Result: Fifty respondents were taken by consecutive sampling and meeting the inclusion criteria. This study also excluded people with depression, schizophrenia, and users of psychotropic drugs. Eighty four percent of respondents with impaired cognitive function. Not much difference in percentage of insomnia disturbance in control group (37,5%) and case group (35,8%). Fisher's Exact Test show Sig.0,609 and OR=0.926 on CI [(0,194),(4,425)]. Conclusion: It was concluded that insomnia alone was not a risk factor for impaired cognitive modalities. Elderly exposed to sleep disorders have the same tendency to suffer cognitive impairment with unexposed.

Comparing Effectiveness of Hay Infusion and Sugar Fermentation Solution as Ovitrap's Attractans to Aedes aegypti Nastiti Widoretno
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 2, No 2 (2018)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v2i2.1232

Dengue Hemorrhagic Fever (DHF) is still one of the major public health problems in the world and Indonesia. There are several methods of mosquito vector control, one of them is the use of ovitrap and the addition of attractants which is a compound that may attract gravid mosquitoes to lay eggs. Some examples of attractants are hay infusion and sugar fermentation solution. This research aimed to compare effectiveness of hay infusion and sugar fermentation solution as Aedes aegypti attractants. This research type was true experimental laboratory with complete randomized design which is divided into 3 groups of ovitrap containing aquades as control, 20% hay infusion and 20% sugar fermentation solution. Ovitraps with those attractants were put into a mosquito coop containing 25 gravid female mosquitoes. Mosquito’s eggs counting was done after 2 days with 9 times repetition. The data were then analyzed using Kruskal-Wallis and Mann-Whitney test. It was found that the difference of mosquito’s eggs number in the ovitrap containing the fermentation solution of sugar and hay infusion had a significance value of 0.000 (p> 0,05). It means that hay infusion is more effective compared with sugar fermentation. Keywords : DHF, ovitrap, attractant, hay infusion, sugar fermentation solution

CA 125 dan Pemakaian Klinis Dalam Penatalaksanaan Kanker Ovarium Ninuk Dwi ariningtyas
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 2, No 2 (2018)
Publisher : Universitas Muhammadiyah Surabaya

Today there are three types of ovarian cancer, namely epithelial cell tumors (70%), which are the largest part of the tumor, Germ cell tumors with a smaller frequency, and sex cord-stroma tumors which is the smallest proportion of about 8% of neoplasm. Ovarian cancer is characterized by unusual early symptoms, real symptoms at advanced stages and low survival rates. Therefore, ovarian cancer is the leading cause of death from gynecological cancer. Over the past decade, several studies have been directed at increasing outcomes of ovarian cancer by performing preclinical screening tests, determining the early stages of disease by using radiological examination or tumor marker serum. The purpose of screening for ovarian cancer is to reduce mortality by detection of stage 1 ovarian invasive epithelial cancer that is potential to be cured. Serum CA 125 measurements are often used to monitor disease status or predict residual disease. A number of cell surface antigens and serum proteins are produced by ovarian tumors and can be tested with monoclonal antibodies. Some of these tests have been clinically applied as a marker of disease and are useful in the detection of subclinical diseases and the diagnosis of recurrent ovarian cancer. Among the multiple biochemical markers in ovarian cancer, the most studied are CA 125. CA 125 is a surface glycoprotein detectable cells in more than 80% of cases of ovarian epithelial cancer. This test is clinically used in the evaluation of mass diagnostics in the ovaries, observation of response to treatment, and further evaluation of patients with ovarian cancer

Analisis Histopatologi Pembuluh Darah Tikus Berdasarkan Jarak Luka Masuk Pasca Paparan Listrik Annisa Sarfina Djunaedy; Ulfa Elfiah; Heni Fatmawati
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 2, No 2 (2018)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v2i2.1237

Electrical injury merupakan suatu kerusakan pada jaringan atau organ tubuh akibat adanya aliran arus listrik yang melewati tubuh. Pembuluh darah merupakan salah satu jaringan yang mengalami kerusakan ketika terjadi electrical injury. Salah satu kerusakan pada pembuluh darah adalah adanya trombus yang dapat mengganggu aliran darah sehingga menyebabkan tatalaksana electric injury menjadi kurang baik. Tujuan umum dari penelitian ini adalah menganalisis histopatologi pembuluh darah tikus berdasarkan jarak luka masuk pasca paparan listrik. Jenis penelitian yang digunakan adalah penelitian eksperimental sebenarnya dengan rancangan post test only control group design. Penelitian ini menggunakan 25 ekor tikus wistar yang dibagi menjadi lima kelompok. Perlakuan yang diberikan berupa paparan listrik sebesar 140 V selama 17 detik. Kelompok kontrol merupakan kelompok yang tidak diberi paparan listrik, kelompok H0 diterminasi pada hari ke-0 pasca paparan listrik, kelompok H3 diterminasi pada hari ke-3 pasca paparan listrik, kelompok H7 diterminasi pada hari ke-7 pasca paparan listrik, kelompok H10 diterminasi pada hari ke-10 pasca paparan listrik. Pada penelitian ini, hal yang diamati yaitu persentase trombus pada arteri saphena dekstra berdasaran jarak dari luka masuk. Hipotesis diterima apabila hasil analisis data menggunakan One Way Anova atau Kruskall Wallis menghasilkan p<0.05. Secara garis besar, pada hasil penelitian didapatkan bahwa bahwa persentase trombus semakin berkurang ketika semakin jauh dari luka masuk, kecuali pada kelompok H7. Selain itu, hasil penelitian menunjukkan bahwa secara garis besar persentase trombus bertambah seiring berjalannya waktu dan menurun pada waktu tertentu. Namun, pada penelitian ini didapatkan bahwa tidak terdapat perbedaan yang signifikan secara statistik pada gambaran histopatologi pembuluh darah, khususnya trombus pasca paparan listrik berdasarkan jarak luka masuk di hari ke-0, ke-3, ke-7, dan ke-10.

Toksisitas Senyawa Tembaga(II)Klorida Dihidrat Terhadap Sel Kanker Payudara T74D Secara in vitro Teguh Hari Sucipto; Harsasi Setyawati; Fahimah Martak
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 2, No 2 (2018)
Publisher : Universitas Muhammadiyah Surabaya

Cancer is a transformation of normal cells in the body into malignancy due to the induction of carcinogens. Breast cancer is the second leading cause of death in Indonesia. The field of treatment with inorganic compounds has been widely developed and shows better anticancer activity than organic compounds. This research aims to know the toxicity level of copper value of 29.021 μg/ml. The value of IC 50 obtained <100 μg/ml so that the copperCancer is a transformation of normal cells in the body into malignancy due to the induction ofcarcinogens. Breast cancer is the second leading cause of death in Indonesia. The field oftreatment with inorganic compounds has been widely developed and shows better anticanceractivity than organic compounds. This research aims to know the toxicity level ofcoppervalue of 29.021 μg/ml. The value of IC50obtained<100 μg/ml so that the copper

Triple Curve Scoliosis Presented with Developmental Dysplasia of the Left Hip in Marfan Syndrome Lukas Widhiyanto; Tri Wahyu Martanto; Febrian Brahmana
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 2, No 2 (2018)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v2i2.975

Introduction: Marfan syndrome is an autosomal dominant disorder of connective tissue, and skeletal system involvements are the cardinal features. Triple rigid large major curve in conjunction with developmental dysplasia of the hip in Marfan syndrome is rare then sagittal and coronal imbalance correction on this case is challengingCase Presentation: We reported a case of 12 years old female with Marfan syndrome presented triple rigid large Major curve scoliosis on left cervico-thoracal, right main thoracal and left thorakolumbal, also developmental dysplasia of the left hip has been done correction surgery consist of open reduction following cast immobilization of the left hip, multiple ponte osteotomy and asymetrical pedicle substraction osteotomy to correct sagittal and coronal imbalance.Discussion: the treatment of scoliosis in patients with Marfan syndrome parallels that in patients with idiopathic scoliosis and spinal fusion and instrumentation should be considered for curves greater than 45 to 50 degrees. Posterior technique, Ponte osteotomy correct 10 to 20 degrees and pedicle substraction osteotomy correct 30 to 40 degrees at each segment are effective for managing sagittal and coronal imbalance in scoliosis. Open reduction developmental dysplasia of the hip to overcome complicated coronal balance correction.Conclusion : Detailed planning scoliosis surgery is needed to correct a rare the sagittal and coronal imbalance due to scoliosis complicated with developmental dysplasia of the hip in Marfan syndrome.

Ekstrak Etanol Teh Hijau (Camellia sinensis) Meningkatkan Kadar Folicle Stimulating Hormone (FSH) dan Jumlah Folikel Antral pada Tikus Betina yang Dipapar Sipermetrin Melati Puspita Sari; Sri Winarsih; Tri Yudani Mardining Raras; Karyono Mintaroem
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 2, No 2 (2018)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v2i2.1559

Latar Belakang: Sipermetrin adalah insektisida jenis piretroid sintetik yang dapat menganggu sistem reproduksi. Sipermetrin juga mampu menghasilkan reactive oxygene species (ROS) sehingga bertanggung jawab menimbulkan terjadinya stres oksidatif. Teh hijau (Camellia sinensis) mengandung polifenol sehingga dapat menghambat radikal hidroksil dan enzim prooksidan. Tujuan: Penelitian ini bertujuan untuk membuktikan pemberian ekstrak etanol teh hijau dapat meningkatkan kadar FSH dan jumlah folikel antral pada tikus betina yang dipapar sipermetrin. Metode: Penelitian yaitu true experimental pada 25 ekor tikus betina galur wistar (Rattus norvegicus) yang dibagi menjadi 5 kelompok; KN: tanpa perlakuan, KP: sipermetrin 20 mg/kgBB/hari, P1: sipermetrin 20 mg/kgBB/hari + ekstrak etanol teh hijau 7 mg/kgBB/hari, P2: sipermetrin 20 mg/kgBB/hari + ekstrak etanol teh hijau 14 mg/kgBB/hari, P3: sipermetrin 20 mg/kgBB/hari + ekstrak etanol teh hijau 28 mg/kgBB/hari per oral selama 28 hari. Kadar FSH diukur dengan metode ELISA dan organ ovarium diambil untuk pemeriksaan jumlah folikel antral dengan metode pewarnaan hematoxylin eosin. Hasil: Kadar FSH dan jumlah folikel antral pada tikus betina menunjukkan hubungan yang positif dan kuat dengan nilai koefisien korelasi 0,742 yang berarti peningkatan kadar FSH diikuti penambahan jumlah folikel antral. Ada perbedaan bermakna pada kadar FSH (p=0,005) dan jumlah folikel antral (p=0,001) antara kelompok kontrol dengan kelompok perlakuan. Kesimpulan: Pemberian ekstrak etanol teh hijau dapat meningkatkan kadar FSH dan jumlah folikel antral pada tikus betina yang dipapar sipermetrin.

The Effectiveness of Scaevola tacada Extract (Gaertn roxb) on the Level of Cytokine IL-10 of Strain Sprague dawly (Female Laboratory Rats) Induced by the Staphylococcus Aureus Bactera Andi Sitti Umrah
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 2, No 2 (2018)
Publisher : Universitas Muhammadiyah Surabaya

Background: Staphylococcus aureus is a sort of bacteria causing mastitis on women, generally found after delivery and during breastfeeding. These bacteria stimulate the immune system to respond, during which Sitikon is released. IL-10 is an anti-inflmation that impedes cell damage on the body, so it is required to do a complementary therapy stemming from the extract of Scaevola Taccada extract (Gaertn Roxb), generally known as sea lettuce. This study aimed to examine the effectiveness of Scaevola Taccada extract (Gaertn Roxb) on the level of Sitokin Il-10 of Strain Strain Sprague Dawly (Female Laboratory Rat) induced by the Staphylococcus Aureus Bacteria.Methods: This true experimental study employing pre- and post-test control design used 18 Sprangue Dawley, laboratory rats, that weighed between 200-250g, and that were divided into three groups, each of which comprised of six rats. The negative control group, positive control group and expiremental group were respectively given 1ml of aqua pro injection/250grBB rats, 9.6mg/ml of antibiotic amoxicillin/250gramBB rats, and 9.6mg of antibiotic amoxicillin/250grBB + 400mg/ml of Scaevola Taccada extract (Gaertn Roxb)/kgBB rats for five days. The sea lettuce plants were taken from the district of Pinrang, South Sulawesi. All groups were induced by staphylococcus aureus 0.2 ml x108 ml/CFU. The level of IL-10 was investigated using R&D method system ELISA Rat, in which the data were analyzed using ANOVA + post hoc test formula with the significant value ρ ≤ 0.05 and CI 95%.Results: The empirical evidence showed that there was no a significant different of Sitokin IL-10 level, either before or after the induction of the bacteria staphylococcus aureus for the length of ± 24 hours of all groups (ρ > 0.05). It was also found that there was a different level of IL-10 after the treatment between all of the groups given the value ρ < 0.05. The increase of IL-10 level was higher in the experimental group (mean ± 72,8 pg/ml) compared to the positive control group (mean ± 41, pg/ml).Conclusions: This research concluded that giving the extract of Scaevola taccada (Gaertn)Roxb) was effective in the boost of sitokin IL-10 level as an anti inflammation that plays central role in the stimulation of immune responses and the prevention of lichen imunopatologia development. The extract of sea lettuce (Scaevola taccada (Gaertn)Roxb)) can be given as a complementary therapy.

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