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Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Published by Universitas Muhammadiyah Surabaya
ISSN : 25412272     EISSN : 25489526     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 301 Documents
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Characteristics of Laryngopharyngeal Reflux: A retrospective descriptive study Rizka Fathoni Perdana; Reyna Cesariyani Rahmadianti Rusuldi; Husin Thamrin; Rosa Falerina
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.11647

Abstract

Laryngopharyngeal reflux (LPR) is a condition of reverse flow of gastric and duodenal fluid that reaches the aerodigestive tract, causing inflammation in the upper respiratory tract. Reflux Symptoms Index (RSI) and Reflux Finding Score (RFS) have been used as instruments to determine the symptoms and signs in LPR patients. This study aims to find out the characteristics of patients with LPR. A retrospective descriptive study was performed using medical records as a source of information to obtain the characteristics of patients with LPR in ENT Outpatient Clinic Dr. Soetomo General Academic Hospital Surabaya. The study population is all patients that has been diagnosed with LPR based on RSI >13 and RFS >7 in the period 2018-2019. Our finding shows the total patients diagnosed with LPR were 58. There were 45 patients diagnosed solitarily according to the results of the RSI score, while the RFS was 34 patients. The total patients diagnosed according to both of RSI and RFS were 21 patients. In this study, 67.24% patients with LPR were female, while the male patients were 32.76%. Most patients with LPR belonged to 50 – 59 years (25.86%). The distribution of occupation shows the highest number of patients is unemployed (43.10%). The most frequent and severe complaints from LPR patients were throat clearing, sensation of something sticking in throat or lump, and excess throat mucus or postnasal drip. The laryngoscopy findings compiled on the RFS showed that the most common signs in LPR patients were subglottic edema, thick endolaryngeal mucus, and posterior commissure hypertrophy.
Correlation between exclusive breastfeeding and obesity among children at kindergartens in Una-Una Central Sulawesi Dipta Tejo Nugroho; Sepfrita Katerine Aftabuddin
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.12946

Abstract

Obesity has become a global health problem that strongly correlates with morbidity and mortality. Despite the importance of obesity, there remains a paucity of evidence on obesity among kindergarten children in Tonjouna, Central Sulawesi. Obesity in children is influenced by various factors, one of which is exclusive breastfeeding. This study aims to find the correlation between exclusive breastfeeding and obesity among children aged four to six years in three kindergartens in Una-Una. The study uses a cross-sectional design involving all children at this kindergarten.   Anthropometric measurement was carried out in school before questionnaires were distributed to determine the number of breastfeeding given to the children. The data analysis revealed that 25% of children suffer from obesity. Five out of 68 children or 29.4% of those who get exclusive breast milk suffer from obesity. The statistical analysis using the Chi-square test shows a p-value of 0.002 (p<0.05), which means that exclusive breastfeeding correlates with obesity in children aged four to six years. This is rather disappointing that the percentage of obesity is relatively high. Hence, educating parents and schools about the causes, risks, and ways to prevent obesity is necessary.
Amplification genetic engineering strategy by Crispr-Cas13 Enzymes for detection and treatment COVID-19 mediated with gold nanoparticle (AUNP) Salsabila Farah Rafidah; Ilham Rahmanto; Ardellia Bertha Pratiska
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.11227

Abstract

WHO declared the disease outbreak due to the COVID-19 coronavirus a global pandemic. Indonesian government's efforts to eradicate the pandemic through mass screening have not been effective due to the limitations of the three main modalities used to detect COVID-19, including Rapid Test Diagnostic (RTD) antibodies, RTD antigens, and Reverse Transcriptase-Polymerase Chain Reaction (RT-RTD PCR), In addition, other detection tools are sometimes used, such as Enzyme-Linked Immunosorbent Assay (ELISA) and rapid molecular tests. To eradicate this pandemic, the government needs COVID-19 detection tools that are effective, cheap, fast, and accessible. To determine the application of the genetic engineering strategy of amplification by the CRISPR-cas13 enzyme for detecting and treating COVID-19 mediated by gold nanoparticles (AuNP). This research uses a qualitative literature study with content analysis, observation development, and literature study; an alternative solution to this problem is CRISPR-Cas13, achieved by the SHERLOCK method. This method designs and screens a targeted group of CRISPR RNAs based on the identification of functional crRNAs of SARS-CoV-2. Amplification of CRISPR-Cas13 by SHERLOCK and PAC-MAN enzymes has the potential to be the latest detection and treatment method for gold nanoparticle-mediated COVID-19 (AuNP) in Indonesia.
Severe anemia on the treatment of a Lepra patient with a history of long-term steroid consumption suspect of Cushing syndrome Gede Padmawijaya; Andi Ridwan Jalal; Zakaria Mustari
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.11786

Abstract

ABSTRACT Anemia is a clinical symptom caused by the disruption of erythrocyte formation, bleeding, and premature blood hemolysis. Severe anemia can occur in patients taking dapsone for the treatment of leprosy. Long-term use of steroids is also a predisposing factor for the occurrence of hematological changes and raises the suspicion of Cushing's syndrome. Reportedly a 20-year-old woman with the main complaint of sudden shortness of breath, accompanied by a cough with phlegm. The patient has had a history of multibacillary type leprosy since a month ago. There was a history of steroid consumption for about two years and only stopped a couple of months ago. Physical examination showed the oxygen saturation was 93%, conjunctival anemia, hyperpigmented plaques, tenderness in the abdominal, meteorism, and pitting edema in the upper and lower extremities. Laboratory examination revealed hemoglobin (Hb) level 2.4 mg/dl, erythrocytes 0.8x106/ul, and albumin 3.2g/dl. Peripheral blood smear results suggest refractory anemia and myelodysplasia syndrome. After being treated for seven days, the patient was re-evaluated and controlled at the Internal Medicine outpatient clinic, Syekh Yusuf Hospital. Complex symptoms and limited investigations make it difficult to establish the exact cause. Immediate blood transfusion and management of the underlying disease causing anemia, such as discontinuation of dapsone, are the primary management of this case. Keywords                : severe anemia, leprosy, steroid, Cushing syndrome.Correspondence        : gedepadmawijaya@yahoo.com
The Role of Social Support on Resilience in People Living With HIV/AIDS : A Systematic Literature Review Firman Firman; Sri Yona; Allenidekania Allenidekania
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.12922

Abstract

During the COVID-19 pandemic, it had a fairly heavy psychological impact, so resilience or resilience was needed, especially for people with HIV/AIDS (PLWHA). This study is to determine the role of social support on resilience in people with HIV/AIDS. Resilience is a person's ability to adapt, survive and thrive in difficult situations. This study used a systematic literature review, which was carried out by means of a systematic review of several articles discussing social support and resilience in people with HIV/AIDS. Article criteria include international publication in English and full text. Article searches were carried out in February 2022 through 4 databases, namely PubMed, Wiley, Proquest, and Springer. Search using keyword ("PLWHA" AND "Social Support" OR "Perceived Social Supports" AND "Resilience" OR "Resiliences"). Articles were analyzed using JBI and Prisma tables. Based on the search for articles in the database, 217 articles were found, then selected through systematic stages so that eight selected journals were obtained. This systematic literature review found that social support was an important factor in increasing resilience in PLWHA. The most influential source of support was support from the family, namely: 30.4%, with (P=0.001). The perceived social support can reduce the impact of stress experienced. With high social support, it can reduce the use of harmful substances and increase ART adherence and contribute to improving the patient's health condition. In conclusion, perceived social support can play an important role, especially in increasing resilience, so it impacts the physical and psychological well-being of people living with HIV/AIDS.
Mapping of antibiotic resistance in Multi-Drug Resistance Tuberculosis at RSUD Arifin Achmad, Riau Province Andralia Mayangsasati; Sri Sundari
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.11288

Abstract

 Tuberculosis is a disease caused by the bacteria Mycobacterium tuberculosis. Resistance is a condition where an antibiotic is not able to kill Mycobacterium tuberculosis. The type of research used is descriptive with a mixed-method approach. It was found that most MDR-TB patients were male (67.2%), aged 41-50 years (26.9%), and lived in Pekanbaru City (65.7%). There were 30 patients (44.8%) who underwent microscopic examination, 12 patients (44.4%) who had a previous medical history of TB disease who had been informed finished taking medication by their doctors. Nine patients (33.3%) with a history of inadequate TB treatment. Three patients (11.1%) were confirmed as a treatment failure. Three patients (11.1%) were primary TB and confirmed the result of laboratory tests for resistance to anti-TB drugs. MDR TB patients who smoke were nine patients (33.3%), and DM patients were two people (7.4%). So, information about the characteristics of Multi-Drug Resistance Tuberculosis is needed, and it is hoped that appropriate treatment can be given  
Relationship of knowledge and attitude with smoking habits at low healthy family index Aisyah Lahdji; Hema Dewi Anggraheni; Nina Anggraeni Noviasari; Muhammad Ridhwan Hamdan
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.10859

Abstract

 Smoking is one of the habits that are often done by the people of Indonesia. Smoking habits are influenced by several things, such as knowledge and attitudes. Having good knowledge will tend to avoid smoking habits, and having a positive attitude will make someone stop smoking. This study aims to determine the relationship between knowledge and attitudes toward smoking habits in Tugu District residents with a Low Healthy Family Index. This research is an observational study with a cross-sectional approach carried out in Tugu District with residents with a low Healthy Family Index. The samples used were 81 samples. The analysis used is the Spearman test. The results showed that 34 respondents (42%) had sufficient knowledge, 64 respondents had a negative attitude (79%), 36 respondents were heavy smokers (44.4%), and 45 respondents were moderate smokers (55.6%). The results of the relationship between knowledge and attitudes toward smoking habits are each with p values of 0.000 and 0.005. This study concludes that there is a relationship between knowledge and attitudes toward smoking habits in Tugu District residents with a Low Healthy Family Index.  
The potential of ethanol extracts 96% mature Papaya fruit seeds (Carica papaya L) as anti-diarrhea medicine Wilujeng Suciati; Sri Wahyu Basuki
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.4168

Abstract

Mature papaya fruit seeds (Carica papaya L.) reduce diarrhea because of phytochemical compounds. This study aimed to determine the potential of 96% ethanol extract of mature papaya fruit seeds as antidiarrhea. This study used experimental laboratory research with pre and post-test with control group design. The research subjects were 25 mice divided into 5 groups, KI group (negative control), KII (positive control) loperamide, and KIII-KIV-KV given treatment with a dose (200 mg; 400 mg; 800 mg). A decrease in diarrhea is known by observing the consistency of feces, stool weight, and stool diameter. Data were analyzed by the Kruskal Wallis test and the Mann Whitney Post Hoc test. The results of the consistency of feces in group K(I) were compared with groups of K(II), K(III), K(IV), K(V) p=0.046, 0.083, 0.014, and 0.014. In stool weight K(I) compared to K(II), K(III), K(IV), K(V) with p=0.053, 0.102, 0.016, and 0.053. In the observation of absorption diameter K(-) compared to K(+), KI(200), KII(400), KIII(800) the p=0.121, 0.0197, 0.051 and 0.21. In conclusion, the mature extract papaya fruit seeds can reduce diarrhea seen from the stool consistency in the group extract 400 and 800 mg/Kilograms body weight and fecal weight in the 400mg/Kilograms body weight extract group.
Informed consent management guidance model of regional anesthesia: Education of young doctors in Teaching Hospitals Titin Setyowati; Aisyah Lahdji
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.13313

Abstract

Informed consent is not necessarily a guarantee for a hospital or health service to avoid disputes between the health provider and the recipient of the health service. This can be caused by the disruption of communication that is less effective and efficient where an Anesthesia Co-Assistant is less clear in delivering the informed consent problem so that the patient has another understanding of what the Anesthesia Co-Assistant is saying. So it takes guidance for Co-Assistant Anesthesia to have comprehensive abilities about a) understanding of regional anesthesia, b) understanding of regional anesthetic techniques, c) understanding of indications and contraindications, d) understanding of drug pharmacology, e) understanding of how to deal with complications, f) understanding of effective communication with patients.
Comparison of functional outcome after early and delayed anterior cruciate ligament reconstruction: A systematic review I Putu Dharma Kresna; Kukuh Dwiputra Hernugrahanto; Rr. Indrayuni Lukitra Wardhani; Dwikora Novembri Utomo
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.11315

Abstract

 This study aims to find the optimal timing for Anterior Cruciate Ligament (ACL) reconstruction by comparing the outcome of early versus delayed ACL reconstruction, meniscus, and chondral damage. A systematic literature search was performed from February to March 2021 from 4 databases. Inclusion criteria were English language Randomized Control Trial (RCT) and observational studies published in 2000-2020, 20-50 years old patients with an isolated ACL tear with/without meniscal injury underwent ACL reconstruction. Early ACL reconstruction was estimated at less than six weeks post-injury, and delayed ACL reconstruction was estimated at more than six weeks. Tegner and Lysholm were the functional outcomes to compare early and delayed ACL reconstruction with a meniscus tear and chondral damage. The search yielded 3094 studies. After removing duplicates, titles and abstracts were screened, leaving 154 potential studies. The studies were selected, and eight studies were eligible. No statistically significant difference between early and delayed ACL reconstruction in Lysholm and Tegner score (p>0,05) was found. Both scores were similar regarding whether the patient performs early/delayed ACL reconstruction. Therefore, early ACL reconstruction could be an optimal timing for the patient who will undergo ACL reconstruction.

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