cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
M. Widyo Wartono
Contact Email
widyo@mipa.uns.ac.id
Phone
-
Journal Mail Official
alchemymipauns@gmail.com
Editorial Address
-
Location
Kota surakarta,
Jawa tengah
INDONESIA
ALCHEMY Jurnal Penelitian Kimia
Published by Universitas Sebelas Maret
ISSN : 14124092     EISSN : 24434183     DOI : -
Core Subject : Science, Social, Engineering,
Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Environmental Science Materials Science & Nanotechnology
ALCHEMY Jurnal Penelitian Kimia is a chemistry journal published by Sebelas Maret University, Surakarta. ALCHEMY Jurnal Penelitian Kimia publishes original research articles or review articles in organic chemistry, inorganic chemistry, analytical chemistry, physical chemistry, biochemistry, and environmental chemistry.
Arjuna Subject : -
Articles 281 Documents
 21   22   23   24   25 
Karakterisasi Pektin yang Diekstraksi dari Kulit Pisang Ambon Hijau (Musa acuminata Colla) dengan Spektroskopi FT-IR dan Analisis Kemometrik Indrawati, Renny; Nitte, Olivia Laura; Yuniati, Yuyun
ALCHEMY Jurnal Penelitian Kimia Vol 20, No 1 (2024): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.20.1.70208.1-11

Abstract

Limbah kulit buah pisang ambon hijau (Musa acuminata Colla) merupakan salah satu kandidat bahan baku pektin yang murah dan mudah ditemukan. Ekstraksi pektin dapat dilakukan dengan berbagai metode dan pelarut asam, namun akan mempengaruhi rendemen serta karakteristik pektin yang dihasilkan. Di sisi lain, spektroskopi FTIR dapat digunakan untuk karakterisasi pektin secara cepat, mudah, dengan sejumlah kecil sampel, tetapi data spektrum vibrasi pada rentang bilangan gelombang yang cukup luas seringkali tidak mudah dibedakan antar sampel. Analisis kemometrik multivariat dapat diterapkan untuk memudahkan analisis data. Tujuan penelitian ini adalah untuk membandingkan karakteristik pektin yang diekstraksi dari kulit pisang dengan variasi pelarut (asam klorida dan asam sitrat) dan waktu ekstraksi (5, 10, dan 15 menit) menggunakan metode microwave, serta melakukan komparasi pektin hasil ekstraksi terhadap pektin komersial dengan metode analisis FTIR dan kemometrik. Hasil penelitian menunjukkan keberhasilan ekstraksi pektin yang dikonfirmasi dengan adanya vibrasi gugus fungsi pektin pada spektrum FTIR. Analisis semi-kuantitatif dengan perbandingan data serapan gugus karboksil teresterifikasi dan karboksil bebas menunjukkan pektin hasil ekstraksi dengan pelarut asam sitrat memiliki derajat esterifikasi lebih tinggi dibandingkan hasil ekstraksi dengan asam klorida. Analisis komponen utama mengonfirmasi kedekatan spektrum pektin hasil ekstraksi dengan asam sitrat ataupun asam klorida selama 10 menit dengan spektrum pektin komersial.Characterization of Pectin Extracted from Banana Peels (Musa acuminata Colla) using FTIR Spectroscopy and Chemometric Analysis. The peel of green banana Musa acuminata Colla is a potential source of pectin. Pectin extraction can be performed using various methods and solvents, but it might influence the characteristics of the result. On the other hand, FTIR spectroscopy can be used to rapidly and simply characterize pectin, but the vibrational data over a wide range of wavenumbers is not easily distinguished between samples. Multivariate chemometric analysis can be applied to ease data analysis. This study aimed to compare the characteristics of pectin obtained after microwave-assisted extraction of the banana peels using different solvents (hydrochloric acid and citric acid) and extraction time (5, 10, and 15 minutes), as well as to compare those pectins toward its commercial grade using chemometric analysis. The result showed successful pectin extraction, as revealed by particular vibrations of functional groups in the pectin structure. Based on semi-quantitative analysis, the absorption band ratio between esterified carboxyl groups and free carboxyl groups revealed that the pectin extracted using citric acid had a higher degree of esterification than that extracted using hydrochloric acid. Principal component analysis confirmed the closeness of pectin obtained after 10 minutes of extraction using citric acid or hydrochloric acid to that of commercial pectin.
Studi Bioakumulasi Ion Logam Pb(II) oleh Tumbuhan Mangrove (Sonneratia alba) di Perairan Desa Passo Kota Ambon Abraham Mariwy; Sunarti Sunarti; Cynthia T Tewernussa
ALCHEMY Jurnal Penelitian Kimia Vol 20, No 2 (2024): September
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.20.2.74274.267-277

Abstract

ABSTRAK. Jenis partikel dan kandungan Pb pada sedimen, akar dan daun, adalah variabel penting untuk mempelajari akumulasi ion logam Pb(II) oleh tumbuhan mangrove pada perairan Desa Passo Kota Ambon. Jenis partikel sedimen dianalisis menggunakan sieve shaker. Kandungan logam timbal (Pb) pada sedimen, akar dan daun mangrove diukur menggunakan spektrofotometer serapan atom. Kemampuan akumulasi dan translokasi timbal (Pb) pada tumbuhan mangrove (Sonneratia alba) diketahui dari nilai BCF (bioconcentration factor) dan TF (translocation factor). Hasil penelitian menunjukkan bahwa jenis partikel pada stasiun I untuk graval 33,55%, pasir 63,38%, dan lumpur 0,98%, pada stasiun II graval 28,41%, pasir 70,06%, dan lumpur 3,01%, dan stasiun III untuk graval 49,69%, pasir 51,24%, dan lumpur 2,83%. Kandungan logam  timbal (Pb) pada sedimen, akar dan daun di stasiun I secara berturut-turut adalah 41,53; 7,04; dan 2,52 mg/kg; pada stasiun II secara berturut-turut sebesar 44,34; 1,12; dan 3,12 mg/kg; sedangkan pada stasiun III sebesar 43,19; 15,37; dan 20,31 mg/kg. Nilai BCF yang diperoleh pada stasiun I, II, dan III secara berturut-turut yakni 0,22; 0,09; 0,82. Nilai TF pada stasiun I, II, dan III berturut-turut adalah 0,35, 2,78, 1,32. ABSTRACT. (Pb(II) Metal Ions Bioaccumulation Study by Mangrove Plants (Sonneratia alba) in Passo Village Waters Ambon City). Particle types and Pb content in sediments, roots, and leaves are important variables in studying the accumulation of Pb metal by mangrove plants in Passo Village Ambon City waters. Sediment particles were analyzed using a sieve shaker. The content of lead metal (Pb) in sediments, roots, and leaves of mangroves was measured using an atomic absorption spectrophotometer. The ability of lead (Pb) accumulation and translocation in mangrove (Sonneratia alba) plants is known from the BCF (bioconcentration factor)  and TF (translocation factor) values. The results showed that the particle available at station I for gravel 33.55%, sand 63.38%, and mud 0.98%, at station II for gravel 28.41%, sand 70.06%, and mud 3.01 %, and at station III for gravel 49.69%, sand 51.24%, and mud 2.83%. Metal lead (Pb) content in sediments, roots, and leaves in station I were 41.53, 7.04, 2.52 mg /kg, in station II were 44.34, 1.12, 3.12 mg/kg, while in station III were 43.19, 15.37, 20.31 mg/kg, respectively. The BCF values obtained at stations I, II, and III were 0.22, 0.09, and 0.82, respectively. The TF values at stations I, II, and III were 0.35, 2.78, and 1.32, respectively.
TiO2-N/Polystyrene photocatalyst-combined Corona Plasma Treatment for Methylene Blue Degradation Kusumandari Kusumandari; Ahmad Qusnudin; Teguh Endah Saraswati; Davit Dhruv
ALCHEMY Jurnal Penelitian Kimia Vol 20, No 1 (2024): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.20.1.76692.62-69

Abstract

This study employed the corona plasma method combined with TiO2-N/PS photocatalyst to degrade dye pollutants. The plasma reactor consisted of two needle-shaped stainless steel electrodes connected to a voltage of 8 kV. Methylene blue (MB) solution was used as a model pollutant with varied initial concentrations of 10, 50, and 100 ppm. The degradation efficiency was evaluated based on the absorbance of the degraded MB solution measured using a UV-Vis spectrophotometer. The results exhibited that the longer plasma treatment duration caused the absorbance value of the degraded MB to decrease, and then the MB degradation efficiency increased. MB-10 demonstrated a maximum degradation efficiency of 99.40% after plasma treatment for 30 minutes. Meanwhile, MB-50 and MB-100 reached maximum degradation efficiencies of 95.29 and 86.55% efficiency after plasma treatment for 60 minutes. The greater initial MB concentration caused the longer degradation process. Furthermore, the results revealed no increase in degradation efficiency due to the addition of TiO2-N/PS photocatalyst into the plasma treatment. The degradation efficiencies of MB-10, MB-50, and MB-100 under TiO2-N/PS-combined plasma treatment for 30 min were 94.48, 81.57, and 5.22%, respectively. This suggests the possibility that the UV light generated during the plasma process cannot activate the TiO2-N/PS photocatalyst.
Nessler Method Verification for Determining Ammonia in Shrimp Pond Wastewater and Its Application in the Ammonia Adsorption Test with Lampung Natural Zeolite Ni Luh Gede Ratna Juliasih; Lia Madyo Ratri; Andi Setiawan; Mita Rilyanti; Rinawati Rinawati; Agung Abadi Kiswandono; Fitri Kurniawati
ALCHEMY Jurnal Penelitian Kimia Vol 20, No 2 (2024): September
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.20.2.72456.257-266

Abstract

Ammonia levels exceeding 0.50 mg/L can threaten organisms in aquatic environments. The Nessler method is one of the ammonia analysis methods based on the reaction between ammonia in a basic solution and Nessler reagent (K2HgI4), forming a colloidal dispersion with a brownish-yellow colour. The colour intensity is determined by spectrophotometry. This research aims to verify the Nessler method for determining ammonia levels in shrimp pond wastewater. The research results indicate that the Nessler method shows good linearity in the range of ammonia concentrations from 1 to 5 mg/L, with a correlation coefficient (R2) value of 0.9962. The precision value was determined from repeatability, expressed as %RSD (Relative Standard Deviation), i.e., 1.92%, and it meets acceptance criteria, which should be less than 0.5 of the Horwitz RSD. The accuracy obtained from the standard addition method provides a percentage recovery value of 99.25%, meeting the AOAC acceptance criteria. The detection limit and quantification limit of the technique are 0.3883 mg/L and 1.2943 mg/L, respectively. The verified method is then applied to analyze shrimp pond wastewater samples from Sriminosari Village, East Lampung, resulting in an ammonia concentration of 1.52 mg/L. The ammonia levels were then reduced by adsorption with natural zeolite Lampung, decreasing ammonia levels by 20.30%. Meanwhile, adsorption with an activated zeolite reduced the ammonia levels by 45.30%.
Preparation and Characterization of Carbon/Si Nanocomposites Synthesized by Chemical Vapor Deposition (CVD) Using SiC and SiO2 Retno Duwi Hardini; Teguh Endah Saraswati; Sentot Budi Rahardjo; Alaa Keshtta
ALCHEMY Jurnal Penelitian Kimia Vol 20, No 2 (2024): September
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.20.2.80438.218-225

Abstract

Carbon-based nanocomposite materials have attracted the attention of researchers in the last decade due to their unique properties applicable in wide applications. This study aims to synthesize and study the characteristics of the carbon-based nanocomposite material produced using the chemical vapor deposition (CVD) method with SiC and SiO2. The CVD process was carried out at 900 ℃ in a vacuum with flowing argon, hydrogen, and acetylene gases. The CVD process produced nanocomposites with more sp3 hybridized carbon atoms, as indicated by the D peak in the Raman spectra. The diffraction pattern analyses show that the resulting carbon powder nanocomposite growth with SiC powder (CSiC) reveals a carbon diffraction peak C(002) and has an elongated form confirmed by an electron microscope. In comparison, the resulting carbon powder nanocomposite growth with SiO2 powder (CSiO2) has a spherical form and presents a carbon diffraction peak C(002). CSiC nanocomposites showed both symmetric and asymmetric C‒H stretching. In FTIR data, CSiO2 nanocomposites show more intense O‒H group peaks but lower-intensity C‒H group vibrations.
Pengaruh Variasi Konsentrasi Gliserol pada Ekstraksi Glukomanan dari Umbi Porang (Amorphophallus oncophyllus) Triana Kusumaningsih; Melinia Puspita Prahastiwi; Venty Suryanti
ALCHEMY Jurnal Penelitian Kimia Vol 20, No 1 (2024): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.20.1.79438.138-150

Abstract

Kandungan glukomanan yang tinggi pada umbi tanaman porang (Amorphophallus oncophyllus) telah menjadikannya sebagai salah satu sumber glukomanan potensial di Indonesia. Glukomanan yang dikenal dengan kandungan gulanya yang rendah, dapat menjadi makanan pengganti beras yang sehat. Penelitian ini berfokus pada ekstraksi glukomanan menggunakan gliserol, penentuan kadar proksimat, dan penilaian kadar kalsium oksalat dalam glukomanan. Gliserol cairan yang tidak berwarna, tidak berbau, berasa manis, dan tidak beracun, digunakan dalam proses ekstraksi. Ekstraksi glukomanan melibatkan maserasi dengan berbagai konsentrasi gliserol (45, 65, dan 85% v/v). Proses maserasi dilakukan dengan pengadukan pada 12.000 rpm selama 1 jam, diulang dua kali, dan diikuti dengan tiga kali pencucian dengan air suling. Untuk mengurangi kadar kalsium oksalat pada umbi porang, dilakukan perendaman dalam larutan NaCl 10% dan 20% (b/v) pada suhu 80°C selama 30 menit. Konsentrasi gliserol 85% (v/v) memberikan hasil yang optimal untuk ekstraksi glukomanan, menghasilkan glukomanan dengan kandungan 61,2%. Analisis proksimat menunjukkan glukomanan dengan kadar lemak 0,29%; protein 2,33%; karbohidrat 9,41%; air 9,40%; dan abu 2,08%. Konsentrasi NaCl yang paling efektif untuk menurunkan kadar kalsium oksalat adalah 20%, yang menghasilkan penurunan kadar kalsium oksalat sebesar 88,44%. Effect of Glycerol Concentration Variation on Glucomannan Extraction from Porang Tubers (Amorphophallus oncophyllus). Due to the high glucomannan content in its tubers, the porang plant (Amorphophallus oncophyllus) emerges as a potential glucomannan source in Indonesia. Glucomannan, known for its low sugar content, can serve as a healthy rice substitute. This study focuses on glucomannan extraction using glycerol, determining proximate levels, and assessing calcium oxalate levels in glucomannan. Glycerol, a colorless, odorless, sweet-tasting, and non-toxic liquid, was employed in the extraction process. Glucomannan extraction involved maceration with varying glycerol concentrations (45, 65, and 85% v/v). Maceration, accompanied by stirring at 12,000 rpm for 1 hour, was repeated twice, followed by three washes with distilled water. To reduce calcium oxalate levels in porang tubers, soaking using 10% and 20% (w/v) NaCl solution at 80°C for 30 minutes was carried out. An 85% (v/v) glycerol concentration yielded optimal results for glucomannan extraction, producing glucomannan with a content of 61.2%. Proximate analysis indicated glucomannan with 0.29% fat, 2.33% protein, 9.41% carbohydrates, 9.40% water, and 2.08% ash content. The most effective NaCl concentration for reducing calcium oxalate content was 20%, resulting in an 88.44% reduction in calcium oxalate levels
The Characterization of Capsule Shell from Acid-Hydrolyzed Palm Oil Starch Amalia Khairunnisa; Pratika Viogenta; Nani Kartinah; Desy Aulia Azzahra
ALCHEMY Jurnal Penelitian Kimia Vol 21, No 1 (2025): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.21.1.93550.72-81

Abstract

Acid hydrolysis of palm trunk starch can increase the amylose content in starch, providing a stronger and more stable film. This study aims to obtain the best-modified starch concentration ratio with hydroxypropyl methylcellulose (HPMC) and identify their characteristics. Modifying palm trunk starch was conducted with an acetic buffer using CH3COONa and CH3COOH, decolorizing starch with activated carbon. Manufacturing a capsule shell was performed with weight ratio variations of modified starch and HPMC 1:1 (F1), 2:1 (F2), and 3:1 (F3). All formulations produced firm and elastic capsule shells. The capsule products were consistent in an average weight of F1 (0.10 g), F2 (0.11 g), and F3 (0.14 g). The average disintegration test results were F1 (10 minutes, 27.57 seconds), F2 (6 minutes, 47.06 seconds), and F3 (4 minutes, 34.24 seconds). Tensile strength results were F1 (2.147 MPa), F2 (2.565 MPa), and F3 (2.159 MPa). Fourier Transform Infrared (FTIR) results showed a vibration at a wavenumber of 1560 cm-1 corresponding to the characteristic fingerprint of the C–O vibration stretching in the capsule shell made from starch modified by HPMC. The concentration of modified starch affects the capsule shell’s characteristics, showing that capsule shell F2 (2:1) has the best formulation.
Elektroda Pasta Karbon Termodifikasi Bentonit Alam untuk Analisis Ion Pb(II) dalam Air Laut Irdhawati Irdhawati; Ni Putu Gita Widi Saraswati; Emmy Sahara; Ayu Jyostisya Yotirani Arya Wijana
ALCHEMY Jurnal Penelitian Kimia Vol 21, No 1 (2025): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.21.1.80131.82-93

Abstract

Pada penelitian ini, elektroda pasta karbon termodifikasi bentonit alam digunakan untuk analisis ion Pb(II) dengan teknik voltametri pelucutan anodik. Tujuan penelitian ini untuk meningkatkan kepekaan pengukuran ion Pb(II). Parameter yang dioptimasi yaitu konsentrasi bentonit dalam pasta karbon, waktu deposisi, potensial deposisi, serta laju pindai. Rentang konsentrasi linier, limit deteksi, limit kuantisasi, keberulangan, dan persentase perolehan kembali telah divalidasi. Hasil yang diperoleh yaitu konsentrasi optimum bentonit dalam pasta karbon adalah 12%. Waktu deposisi optimum untuk elektroda pasta karbon (EPK) 120 detik, dan 90 detik menggunakan EPK termodifikasi bentonit alam (EPK-B), potensial deposisi optimum yaitu -0,43 V dengan EPK dan -0,23 V dengan EPK-B, serta laju pindai optimum yaitu 15 mV/s dengan EPK dan EPK-B. Hasil validasi pengukuran ion Pb(II) diperoleh konsentrasi linear pada rentang 10 – 1000 μg/L dengan EPK dan 5 – 500 μg/L dengan EPK-B. Limit deteksi dan limit kuantisasi masing-masing pengukuran yaitu 0,08 mg/L dan 0,25 mg/L menggunakan EPK, dan 0,19 mg/L dan 0,64 mg/L menggunakan EPK-B. Keberulangan pengukuran diperoleh nilai lebih kecil dari dua untuk kedua elektroda kerja. EPK-B pada kondisi optimum digunakan untuk menentukan konsentrasi ion Pb(II) dalam sampel air laut, diperoleh hasil 1,47 ± 0,31 mg/L.Carbon Paste Electrode Modified with Natural Bentonite for Analysis of Pb(II) Ion in Seawater. This research used a modified bentonite carbon paste electrode for Pb(II) ion analysis using the anodic stripping voltammetry technique. This research aims to increase the sensitivity of Pb(II) ion measurement. Optimized parameters were the concentration of natural bentonite in carbon paste, deposition time, deposition potential, and scan rate. The range of linear concentration, detection limit, quantitation limit, repeatability, and recovery percentage were validated. The results were obtained the optimum concentration of natural bentonite in carbon paste at 12%. The optimum deposition time with carbon paste electrode (CPE) was 120 seconds and with natural bentonite-modified carbon paste electrode (CPE-B) was 90 seconds, the optimum deposition potential with CPE was -0.43 V, and with CPE-B was -0.23 V, the optimum scan rate for both working electrodes had the same value of 15 mV/s. Pb (II) ion measurements were obtained in the linear concentration range of 10 – 1000 μg/L using CPE and 5 – 500 μg/L using CPE-B. The detection and quantitation limits were found at 0.08 mg/L and 0.25 mg /L for CPE, and 0.19 mg /L and 0.64 mg /L using CPE-B, respectively. The repeated measurements for both CPE and CPE-B produced Horwitz ratio values were less than two. CPE-B at the optimum measurement conditions was used to measure the concentration of Pb (II) ion in seawater sample, found at 1.47 ± 0.31 mg/L.
Phytochemical and Pharmacological Properties of Myristica fragrans Leaves Houtt. Ariyanti Saputri; Sofa Fajriah; Antonius Herry Cahyana
ALCHEMY Jurnal Penelitian Kimia Vol 21, No 1 (2025): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.21.1.93701.17-32

Abstract

Myristica fragrans is a widely distributed plant that grows well in Indonesia. This plant, also known as nutmeg, has been used in various fields such as food, aromatherapy, and other industries. Research on nutmeg plants has been widely conducted, but most of it discusses the seeds and mace of nutmeg. However, research on nutmeg leaves is still limited, with only a few studies to be discussed in this review article. This article provides an overview of the chemical compounds, bioactivity, and toxic effects of essential oils and nutmeg leaf extracts collected from the latest literatures (2014–2024). This article aims to draw more attention to nutmeg leaf research to be developed into natural-based medicinal products. Some compounds contained in nutmeg leaves include dihydrokaempferol, myristicin, 1,1,3,3,5,5,7,7,9,9,11,11,13,13-tetradecamethylheptasiloxane, 2,2-dimethyl-1-decanol, bis(2-ethyl hexyl) phthalate, and 9-dodecane-1-al, gamma-terpinene; caryophyllene and others. In addition, nutmeg leaf compounds also have various interesting bioactivities such as antibacterial, antifungal, antioxidant, larvicidal, and good cytotoxic activity. Overall, nutmeg leaves show great potential as a raw material for medicine. The results of this study also show various types of secondary metabolites with interesting bioactivities that require further study.
Implementation of FTIR-Based Fingerprinting, Antioxidant Compounds Profiling by UHPLC-Q-Orbitrap HRMS, and Docking Study COVID-19 Inhibitor of Buas-Buas (Premna serratifolia) Leaf Extract from Pontianak Indonesia Dini Hadiarti; Mahwar Qurbaniah; Ely Setiawan; Taufan Hari Sugara
ALCHEMY Jurnal Penelitian Kimia Vol 21, No 1 (2025): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.21.1.92020.149-161

Abstract

This research aims to profile the active antioxidant compounds from leaf extracts of Buas-buas (Premna serratifolia) growing in Pontianak of West Kalimantan (Indonesia) through a metabolomics approach and their activity as anti-COVID-19 candidates by molecular docking. In this study, P. serratifolia leaves were macerated and fractionated using solvents with different polarities. The extracts were then tested for antioxidant activity using the DPPH method, determined the total phenolic content (TPC), flavonoids (TFC), and steroids (TSC), and analyzed antioxidant the functional groups and compounds by Fourier Transform Infrared spectroscopy (FTIR) and Ultra High-Performance Chromatography UHPLC-Q-Orbitrap HRMS. The functional groups on antioxidant activity were determined by Principal Component Analysis (PCA) and Partial Least Square (PLS) regression. Based on a metabolomics approach, the PCA and PLS analysis shows that hydroxyl was the most active antioxidant from P. serratifolia leaves. UHPLC-Q-Orbitrap HRMS analysis showed the presence of scopoletin, esculetin, 7-hydroxycoumarine, matairesinol, hymecromone, and hexylresorcinol in the water fraction of P. serratifolia leaves. Molecular docking with 4YE6, 1OG5, and 3NRZ shows that matairesinol had the most potential as an antioxidant. Mataresinol and hexyresorcinol are phenolic compounds that have great potential as a COVID-19 inhibitor based on molecular docking with 5R81, 7CMD, and 6M2N.

Page 23 of 29 | Total Record : 281

 21   22   23   24   25 

Filter by Year

2014 2026


Reset
Filter By Issues
All Issue Vol 22, No 1 (2026): March Vol 21, No 2 (2025): September Vol 21, No 1 (2025): March Vol 20, No 2 (2024): September Vol 20, No 1 (2024): March Vol 19, No 2 (2023): September Vol 19, No 1 (2023): March Vol 18, No 2 (2022): September Vol 18, No 1 (2022): March Vol 17, No 2 (2021): September Vol 17, No 1 (2021): March Vol 16, No 2 (2020): September Vol 16, No 1 (2020): March Vol 15, No 2 (2019): September Vol 15, No 1 (2019): March Vol 14, No 2 (2018): September Vol 14, No 1 (2018): March Vol 13, No 2 (2017): September Vol 13, No 1 (2017): March Vol 12, No 2 (2016): September Vol 12, No 1 (2016): March Vol 11, No 2 (2015): September Vol 11, No 1 (2015): March Vol 10, No 2 (2014): September Vol 10, No 1 (2014): March More Issue