Garuda - Garba Rujukan Digital

All

Jurnal Kimia Terapan Indonesia

InaJAC
Website

Published by Lembaga Ilmu Pengetahuan Indonesia

ISSN : 08532788 EISSN : 25277669 DOI : -

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Materials Science & Nanotechnology

Arjuna Subject : -

Articles 283 Documents

18 19 20 21 22

AKTIVITAS ANTIOKSIDAN DAN TOKSISITAS EKSTRAK AIR DAN ETANOL DAUN BENALU (Dendrophthoe pentandra L. Miq) YANG TUMBUH PADA BERBAGAI INANG Nina Artanti; Retno Widayati; Sofa Fajriah
Jurnal Kimia Terapan Indonesia Vol 11, No 1 (2009)
Publisher : Research Center for Chemistry - LIPI

Mistletoes are used traditionally in Indonesiaas medicinal plant, one of this as anticancer. Cancer isone of degenerative diseases could be triggered by toomuch free radicals in the body, whereas antioxidantcould reduced the risk of degenerative diseases.Mistletoes reposted content flavonoids which known have antioxidant activity. Mistletoe potency as drugmaterial should be studied sa the utilization ofmistletoe could be developed. Antioxidant activitytest using "DPPH free radical scavenger" methodand toxicity test using BSLT (Brine Shrimp LethalityTest) method had been conducted on water andethanol extracts of mistletoe Dendropthoe pentandra(L.) Miq.) that grown on various trees (star fruit,mango, cananga, 'duku, sour-sop, kepel, mahkotadewa, and tea). The result showed that ethanol andwater extracte-ofD, petandra on all host plants haveantioxidant activity (IC50 value between 6.4 - 51.8ug/mL). The result of toxicity test showed that ethanolextract of mistletoe on cananga, starfruit, kepel andmahkota dewa host plants have toxicity effect againstA. salina larvae with LCso value below 1000 ug/mL,nevertheless ethanol extract on others host plants andwater extract didn It give toxicity effect against A.salina larvae (LC50 > 1000 ug/mL).Key words: mistletoe, D. petandra, DPPH, antioxidant,toxicity, degenerative disea.

APLlKASI KALSIUM KLORIDA DAN ETHEPHON DALAM UPAYA PENINGKATAN KUALITAS BUAH NANAS (Ananas comosus (L) Merr) Nungki Kusuma Astuti; Moch Dawam Maghfoer; Roedy Soelistyono
Jurnal Kimia Terapan Indonesia Vol 15, No 1 (2013)
Publisher : Research Center for Chemistry - LIPI

The objective of research was to obtain the treatmenttime of CaCl2 applications, dosage of CaCl2 and ethephonapplications to improve the fruit quality of pineapple. Thisresearch used Split-Split Plot Design and each treatmentreplicated 3times. The main plot is time ofCaCl2 applicationsthat consists of three levels, those are 90 day after flowering(daf), 120 daf and twice of CaCl2 applications at 90 and 120daf The sub plot is dosage of CaCl2 that consists of threelevels, those are 50 kg ha', 75 kg ha' and 100 kg ha', The subsub plot is dosage of ethephon that consists of two levels,those areO L ha' and 2,5 L ha', The results showed that thecombined treatment ofCaCl2 application on 90 daf, dosage ofCaCl250 kg ha' and dosage of ethephon 2.5 L ha' producedistribution external fruit maturity level of 25% and 50%higher than the other treatments. Combined treatment twiceof CaCl2 application on 90 and 120 daf with dosage of CaCl2100 kg ha' produces calcium content higher than the othertreatment and produce fruit texture, percentage of fruitdiseases and percentage of fruit bruised lower than othertreatments. Ethephon application had noeffect on calciumcontent but decreasing fruit texture, percentage of fruitdiseases and improved percentage offruit bruised. CaCl2 andethephonapplications didnot affect the total soluble solid,total acidity and vitamin C. .Keywords: CaCl2, ethephon, pineapple, fruit quality.

LOW-TEMPERATURE SYNTHESIS OF LEAD ZIRCONATE TITANATE (PZT) POWDER FROM METAL ALKOXIDES Silvester Tursiloadi; Hiroaki Imai; Hiroshi Hirashima
Jurnal Kimia Terapan Indonesia Vol 5, No 1 (1995)
Publisher : Research Center for Chemistry - LIPI

PZT powder precipitate has been prepared by hydrolyzing a mixture of lead di-i-propoxide, zirconium tetra-n-butoxide and titanium tetrai-propoxide. The crystallization process of the amorphous PZT was studied by means of X-ray diffraction analysis. It was found that the powder precipitate was still amorphous on heating until 400°C for 2k As an intermediate product, metastable cubic Pb2Ti2O6 (pyrochlore phase) was found after heating at 450°C for 2h. In addition to Pb2Ti206 peaks, the diffraction peaks of perovskite PZT phase were observed after heating at 430°C for 24 h. After heating at 600 °C for 2h, only diffraction peaks of tetragonal perovskite PZT phase were found. The lattice parameters of the tetragonal PZT have been obtained to be a=4.066 A c=4.196 A This tetragonal perovskite phase was stable on heating until 1000 "C. The density of the compacted powder precipitate after heating at 1000°C (a relatively low temperature for the sintering of PZT) for 30 min. was 6.1 g/cm3, about 76% of the theoretical value.

PEMANFAATAN KULIT UDANG UNTUK PEMBUATAN KITOSAN DAN GLUKOSAMIN Muhammad Hanafi; Syahrul Aiman; D Efrina; B. Suwandl
Jurnal Kimia Terapan Indonesia Vol 10, No 1-2 (2000)
Publisher : Research Center for Chemistry - LIPI

Shrimp shells as side product of frozen shrimp industry isnot yet used in pharmaceutical or chemical industries. Shrimpshells has a chemical constituent called chitin, calcium carbonateand protein as main compounds. By decalcination in dilute aqueosHCl solution (1-2 N) and deproteination ill dilute aqueos NaOHsolution (3-4 Nj gives a chitin. Deacetylation of chitin in theexcess of aqueous 50 % NaOH solution produces chitosan. Inthe preleminary experiment indicated that water (< 10%) andash (< 2%) content of chit os an same as standard. Based on theexperiment result the optimum condition was obtained as 1N HCIsolution (1: 10), 3N NaOH solution (1:6) and 50 % NaOH solution(1: 5) resulted 12,61 % chitosan with deacetylation degree valueabout 70 % with FT1R methode. Hydrolysis of chitin or chitosanin excess HCl gives glucosamine about 17 %, it's a mixture of aand B-glucosa11line. Glucoseamine is identified using 1H and13C NMR spectrum.

PENAPISAN AKTIVITAS ANTIPROTOZOA DALAM BIJI SAGA (Adenanthera pavonina LINN) Lenny Sutedja
Jurnal Kimia Terapan Indonesia Vol 5, No 1 (1995)
Publisher : Research Center for Chemistry - LIPI

The protozoa Tetrahymena pyriformis GL is an eucaryote. Its metabolism is similar to that of mammalia, so that it is widely used as a biological tool in protein quality as well as toxicity assays. In the framework of searching toxic or antinutritive properties in saga seed (Adenanthera pavonina LINN), extracts of saga bean were tested for their antiprotozoa activity. The saga bean extracts were obtained after successive extraction with nhexane and ethanol. Observation of total and motile cell population indicated that 0,1% saga oil in the medium did not show significant effect on the growth of T.pyriformis GL during 96 hours incubation at 30°C. While ethanol extract of saga showed significant inhibition on the growth of T.pyriformis GL. Smaller cell population was already observed at 7 hours incubation at 30°C. At 24 hours incubation, 0,1% and 1% ethanol extract of saga in the medium showed 55,1% and 87,6% inhibition respectively. Ethanol extract showed the largest anttprotozoal activity compared to the other extract. Qualitative analysis indicated the presence of saponin and alkaloid in the ethanol extract of saga bean. Chromatographic analysis with high performance liquid chromatography showed the presence of at least eight components in the ethanol extract of saga.

DEVELOPMENT AND VALIDATION OF A TLC DENSITOMETRIC METHOD FOR DETERMINATION OF GLIMEPIRIDE IN TABLETS Yuni Retnaningtyas; Lestyo Wulandiri; Gabriella F Punu
Jurnal Kimia Terapan Indonesia Vol 16, No 1 (2014)
Publisher : Research Center for Chemistry - LIPI

A simple and valid TLC method has been developed for the determination of glimepiride in tablet formulation. After extraction of the analyte with a mixture of methanol and ammonia 0,2M (1:1, v/v), the extracts were spotted on precoated TLC silica gel F254 plates, which were developed with a mixture of toluene:methanol:ethyl acetate (75:20:5, v/v/v). Quantitative evaluation was performed by measuring the absorbance reflectance of the analyte spots at 238 nm. The method was validated for specificity, linearity, accuracy and precision. Good linearity was achieved in the concentration range 100â€“800 ng/spot. The RSD of repeatability and intermediate precision were found to be less than 2%, whereas the mean of the recovery data was 100-101%. The detection limit and quantification limit were 22 and 74 ng/spot, respectively. The method is specific, linear, precise, and accurate; it can be used for the routine quality control testing of marketed formulations.Keywords: glimepiride, TLC densitometric, validation of pharmaceutical methods, pharmaceutical analysis, antidiabetic drugÂ Sebuah metode Kromatografi Lapis Tipis (KLT) yang sederhana dan valid telah dikembangkan untuk penentuan glimepiride dalam sediaan tablet. Setelah analit dalam sampel diekstraksi dengan campuran metanol dan amonia 0,2 M (1:1,v/v), ekstrak yang terlihat pada lempeng silika gel F254, yang dikembangkan dengan campuran toluen : metanol : etil asetat (75:20:5, v/v/v). Evaluasi kuantitatif dilakukan dengan mengukur reflektansi absorbansi noda analit pada panjang gelombang 238 nm.Metode ini divalidasi meliputi spesifisitas, linearitas, akurasi dan presisi.Linearitas yang baik dicapai pada rentang konsentrasi 100-800 ng / spot. RSD pengulangan dan presisi intermediate menunjukkan nilai kurang dari 2 %, sedangkan rata-rata data recovery adalah 100-101 % .Batas deteksi dan batas kuantifikasi adalah 22 dan 74 ng / noda.Metode ini spesifik, linear, tepat, dan akurat, bisa digunakan untuk pengujian kontrol kualitas rutin tablet glimepirid dipasarkan. Kata Kunci: glimepiride, TLC densitometric, validation of pharmaceutical methods, pharmaceutical analysis, antidiabetic drug

MENUJU LABORATORIUM ANALISIS LlNGKUNGAN TERPADU DAN TANTANGAN MASA DEPAN Soefjan Tsauri; Soemanto Imamkhasani
Jurnal Kimia Terapan Indonesia Vol 10, No 1-2 (2000)
Publisher : Research Center for Chemistry - LIPI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14203/jkti.v10i1-2.185

An idea on an integrated environmental analytical laboratoryand its challenges for the future were discussed. A generalanalytical laboratory equipped with conventional and instrumentalmethods could be improved to environmental laboratory byaddition of sampler eguipment. These include water sampler, impinger for sampling of ambient air, stack gas sampler andleaching test (TCLP) , all of these have been made locally andtherefore easily purchased with low price. Laboratory accreditationwas also discussed for improving the quality of laboratory as areliable environmental data generator. Accreditation requirementssuch as registration, methods of analysis, quality control, physicalcondition of lab oratory, equipment and instrument were explained.In addition, other challenges in research were pointed out on thearea of semi-micro techniques, sensor, micro-instruments,automation and telemetric system. Experiences showed thatenvironmental analytical laboratory had good challenges forbusiness. Analytical services, development of monitoring systemand training were identified as prospective business in Indonesiaparticularly in East of Java.

Evaluation of Uncertainty in the Determination of Pesticide Residues in Tea using GC-ECD Yohanes Susanto Ridwan; Andreas Andreas; Dyah Styarini; Retno Yusiasih
Jurnal Kimia Terapan Indonesia Vol 19, No 1 (2017)
Publisher : Research Center for Chemistry - LIPI

Key indicator of quality in test results is the uncertainty value, which could be evaluated using several common approach. Uncertainty evaluation in a-endosulfan and bifenthrin in Oolong tea, and cypermethrin in green tea using bottom-up approach showed that uncertainty component arising from GC-ECD instrument calibration, method performance i.e. repeatability and recovery were the main contributors to total uncertainty. Uncertainty component arising from weighing, dilution factor, stock standard solution, calibration solution, and moisture correction had no significant effect to total uncertainty, hence they could be neglected. Relative standard uncertainty obtained for all of pesticides residue were 18.23, 10.44, dan 14.98% for a-endosulfan, bifenthrin, and cypermethrin, respectively. Comparison with 2/3 CV Horwitz of 17.33, 10.62, and 12.44% respectively for all pesticide residues indicated that the evaluation of uncertainties were realistic

OPTIMASI DAN VALIDASI METODA PENGUJIAN WEDELOLAKTON SECARA KROMATOGRAFI CAIR KINERJA TINGGI DENGAN TEKNIK DETEKSI FLUORESENSI (KCKT - F) Iiisna Yuliana; Yosi Aristiawan; Iwan Bastiawanz; Julia J. Kantasubrata; Muljadji Agma
Jurnal Kimia Terapan Indonesia Vol 14, No 1 (2012)
Publisher : Research Center for Chemistry - LIPI

Wedelolakton has a wide range of biologicalactivities and used for the treatment of variousailments. In the present study an experiment ofquantitative determination of wedelolactone inherbal extract of Eclipta alba L. Hask has beendeveloped by using RP - HPLC - Fluorimetrytechnique and mixture methanol:0.35% acetic acid(H20) (50:50 vlv) as mobile phase, applied to theherbal extract as inhouse reference materialcandidate samples. The method was validated forthe confirmation of identity (selectivity), linearity,precision, recovery, sensitifity, limit of detectionJKTI, Vol. 14, No.1, Juni 2012and limit of quantitation. Statistical analysis of thedata showed that the method is reproducible andselective for the estimation of wedelolactonedetermination.Keywords: Wedelolactone, HPLC-F, method optimization,method validation, confidence limi

AMOBILISASI ENZIM PENISILIN ASILASE SEL TRANSFORMAN ESCHERICHIA COLI SC 50 MENGGUNAKAN GEL POLIAKRILAMIDA S. Pudjiraharti; M. Wirahadikusumah
Jurnal Kimia Terapan Indonesia Vol 4, No 1 (1994)
Publisher : Research Center for Chemistry - LIPI

Results of study on the immobilization of dialysed fraction of penicillin acylase using various concentrations of acrylamide at BIS concentration 0,8 % are described. The study is an effort to increase the stability and efficiency of the enzyme use. The highest specific activity of the immobilized enzyme (1.38 U/mg protein) was found on immobilization using acrylamide 12.5 %. The penicillin acylase used in this study was obtained from the extraction of Escherichia coli Sc 50 cells. The optimum conditions of catalytic reaction of the enzyme were found 65°C and pH 7.00 both for immobilized and free enzymes. Theoptimum catalytic time was 230 minutes for the immobilized enzyme and 100 minutes for the free one. The immobilized enzyme was found more stable against pH, temperature changes, and storage at the experimental conditions and could be used five times repeatedly with remaining activity of 50 %. The Km value of free enzyme was 7.21 mM and the Vmax was 0.065 unol 6APA/mg protein/minute. Immobilization increased the Km value to 20.26 mM, and decreased Vmax to 0,033 unol 6-APA/mg protein/ minute. Phenylacetic acid was found to be a mixed inhibitor for penicillin acylase E. coli Sc 50 with the inhibition constants of Ki 720.31 mM and Ki' 504.31 mM. Immobilization decreased Ki to 176.58 mM and Ki' to 27.61 mM.

Page 20 of 29 | Total Record : 283

18 19 20 21 22

Filter by Year

1991 2022

Filter By Issues

All Issue Vol 24, No 1 (2022): Jurnal Kimia Terapan Indonesia Vol 23, No 2 (2021): Jurnal Kimia Terapan Indonesia Vol 23, No 1 (2021) Vol 22, No 1 (2020) Vol 21, No 2 (2020) Vol 21, No 1 (2019) Vol 20, No 2 (2018) Vol 20, No 1 (2018) Vol 19, No 2 (2017) Vol 19, No 1 (2017) Vol 18, No 02 (2016) Vol 18, No 01 (2016) Vol 17, No 2 (2015) Vol 17, No 1 (2015) Vol 16, No 2 (2014) Vol 16, No 1 (2014) Vol 15, No 2 (2013) Vol 15, No 1 (2013) Vol 14, No 2 (2012) Vol 14, No 1 (2012) Vol 13, No 2 (2011) Vol 13, No 1 (2011) Vol 12, No 2 (2010) Vol 12, No 1 (2010) Vol 11, No 2 (2009) Vol 11, No 1 (2009) Vol 10, No 1-2 (2000) Vol 9, No 1-2 (1999) Vol 8, No 1-2 (1998) Vol 7, No 1-2 (1997) Vol 6, No 1-2 (1996) Vol 5, No 1 (1995) Vol 4, No 2 (1994) Vol 4, No 1 (1994) Vol 3, No 2 (1993) Vol 3, No 1 (1993) Vol 2, No 1-2 (1992) Vol 1, No 2 (1991) Vol 1, No 1 (1991) More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota adm. jakarta selatan,

Dki jakarta

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kota adm. jakarta selatan, Dki jakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota adm. jakarta selatan,

Dki jakarta

INDONESIA