Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Indonesian Journal of Chemistry

ijc
Website

Published by Universitas Gadjah Mada

ISSN : 14119420 EISSN : 24601578 DOI : -

Core Subject : Science, Engineering,

Chemical Engineering, Chemistry & Bioengineering Chemistry

Indonesian Journal of Chemistry is an International, peer-reviewed, open access journal that publishes original research articles, review articles, as well as short communication in all areas of chemistry including applied chemistry. The journal is accredited by The Ministry of Research, Technology and Higher Education (RISTEKDIKTI) No : 21/E/KPT/2018 (in First Rank) and indexed in Scopus since 2012. Since 2018 (Volume 18), Indonesian Journal of Chemistry publish four issues (numbers) annually (February, May, August and November).

Arjuna Subject : -

Articles 1,956 Documents

1 2 3 4 5

Synthesis of Zeolite NaA from Low Grade (High Impurities) Indonesian Natural Zeolite Asalil Mustain; Gede Wibawa; Mukhammad Furoiddun Nais; Miftakhul Falah
Indonesian Journal of Chemistry Vol 14, No 2 (2014)
Publisher : Universitas Gadjah Mada

The zeolite NaA has been successfully synthesized from the low grade natural zeolite with high impurities. The synthesis method was started by mixing natural zeolite powder with NH4Cl aqueous solution in the reactor as pretreatment. The use of pretreatment was to reduce the impurities contents in the zeolite. The process was followed by alkaline fusion hydrothermal treatment to modify the framework structure of natural zeolite and reduce the SiO2/Al2O3 ratio. Finally, the synthesized zeolite was calcined at 600 °C for 2 h. The final zeolite product was characterized by X-ray fluorescence (XRF), X-ray diffraction (XRD) and scanning electron microscopy (SEM). The results showed that the morphology of the zeolite NaA was cubic shape as observed by SEM analysis and the synthesized zeolite NaA with pretreatment gave less impurity than without pretreatment.

FLAVANONES FROM THE WOOD OF Morus nigra WITH CYTOTOXIC ACTIVITY Ferlinahayati Ferlinahayati; Yana Maolana Syah; Lia Dewi Juliawaty; Euis Holisotan Hakim
Indonesian Journal of Chemistry Vol 13, No 3 (2013)
Publisher : Universitas Gadjah Mada

Two flavanone derivatives, norartocarpanone (1) and euchrenone a7 (2) had been isolated for the first time from the methanol extract of the wood of Morus nigra. The structures of these compounds were determined base on spectral evidence, including UV, IR, and NMR. The first compound also confirmed by comparison with the reported data. Cytotoxic properties of these compounds were evaluated against murine leukemia P-388 cells. Euchrenone a7 (2) was found more cytotoxic than norartocarpanone (1) with their IC50 7.8 and 12.7 mg/mL respectively.

SYNTHESIS AND CYTOTOXIC ACTIVITY OF CHALCONE DERIVATIVES ON HUMAN BREAST CANCER CELL LINES Nuraini Harmastuti; Rina Herowati; Dyah Susilowati; Harno Dwi Pranowo; Sofia Mubarika
Indonesian Journal of Chemistry Vol 12, No 3 (2012)
Publisher : Universitas Gadjah Mada

Chalcone, an α,β-unsaturated ketone, has been shown have many biological activities such as anticancer and antifungi. This research was conducted to synthesize the chalcone derivatives and to obtain their cytotoxic activity on human cervix cancer cell lines. Synthesis of chalcone and its derivatives, 4II-methylchalcone, 4II-methoxychalcone, and 3II,4II-dichlorochalcone was carried out using starting materials of benzaldehide and acetofenon, p-methylacetophenone, p-methoxyacetophenone, as well as m,p-dichloroacetophenone through Claisen Schmidt condensation catalized by NaOH in ethanol at 15 °C. The purity of synthesized compounds were analyzed by thin layer chromatography, melting range, and gas chromatography. Structure elucidations were conducted by UV spectrophotometer, IR spectrometer, 1H-NMR spectrometer, as well as mass spectrometer. Cytotoxic activities were determined by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) microculture tetrazolium viability assay. The results showed that chalcone and derivatives compounds have been able to be synthesized and purified and had the same structure as a predicted structure. Chalcone had highest cytotoxic activity compared to that of its derivatives, with the IC50 values of chalcone, 4II-methylchalcone, 4II-methoxychalcone, and 3II,4II-dichlorochalcone were 9.49, 14.79, 11.48, and 24.26 µg/mL respectively. It was concluded that methyl, methoxy as well as chlorine substitution at 3 II and 4II position decrease the cytotoxic activity of chalcone.

Characterization of Butanediol-Alginate Ester as Candidate of Hemodialysis Membrane Choirul Amri; Mudasir Mudasir; Dwi Siswanta; Roto Roto
Indonesian Journal of Chemistry Vol 15, No 2 (2015)
Publisher : Universitas Gadjah Mada

An ester of butanediol-alginate has been studied as a possible hemodialysis membrane. With 1,4-butanediol molar ratio of 0.1, 0.5, and 1.0, it showed that the membrane mechanical properties, stability, protein adsorption, platelet adhesion and performance for urea and creatinine clearance are better than that of unmodified alginate. The increase in 1,4-butanediol molar ratio causes hemodialysis ratio to improve, and causes protein adsorption and platelet adhesion at the membrane surface to decrease. In the case of protein adsorption and platelet adhesion, the membrane with the molar ratio of 1.0 has better hemocompatibility properties. In the hemodialysis test for 4 h, using 2.742 mg cm-2 h-1 of urea and 0.058 mg cm-2 h-1 of creatinine flux, this membrane showed that 48.5% of urea and 44.2% of creatinine were cleaned.

Synthesis and Characterization of [Fe(picolinate)3][MnNi(oxalate)3].CH3OH Polymeric Complex Fahimah Martak; Djulia Onggo; Ismunandar Ismunandar; Agung Nugroho
Indonesian Journal of Chemistry Vol 14, No 3 (2014)
Publisher : Universitas Gadjah Mada

Polymeric complex [Fe(picolinate)3][MnNi(oxalate)3].CH3OH has been successfully synthesized using H-tube technique. The chemical composition of the synthesized product was determined by Elemental Analysis and Atomic Absorption Spectrometry. Infrared spectrum shows that the oxalate ligand acts as a bridging ligand. The crystalline product exists in the form of monoclinic structure and space group P21n as shown on the pattern of X-Ray Diffraction and has a similar structure with [Fe(bpp)2][MnCr(oxalate)3] complex. The magnetic susceptibility of the polymeric complex exhibits high spin and paramagnetic behavior.

THE INFLUENCE OF PVA.cl.CITRIC ACID/CHITOSAN MEMBRANE HYDROPHICILITY ON THE TRANSPORT OF CREATININE AND UREA Retno Ariadi Lusiana; Dwi Siswanta; Mudasir Mudasir; Takashi Hayashita
Indonesian Journal of Chemistry Vol 13, No 3 (2013)
Publisher : Universitas Gadjah Mada

The influence of cross-linking and membrane hydrophilicity on the transport rate had been studied using a membrane prepared from a mixture of chitosan/PVA cross-linked citric acid (PVA.cl.CA) for creatinine and urea transport. The optimum mole ratio of PVA:citric acid as well as the best composition of chitosan:PVA.cl.CA were determined using creatinine transport study. Using the optimum compositions, further study was done using different thickness of the membrane in transporting creatinine, urea and a mixture of 3 species (creatinine, urea and vitamin B12). Membrane characterization was done using FT-IR spectrophotometer, water absorption test, TG/DTG and SEM. The results showed that the optimum composition PVA:citric acid was obtained to be 90:1, having % WU of 113.74% and creatinine transport percentage of 18.16%. Meanwhile, the optimum composition of chitosan:PVA.cl.CA was found at 4:6 ratio having % WU and % transport of 136.67% and 24.26%, respectively. The optimum transport capacity was found for membrane thickness of 50 µm with WU% at 139.61% and the percent transport of creatinine and urea each was 38.93% and 60.36%. The presence vitamin B12 in the solution of is proved to disturb the transport of creatinine and urea through the membrane. Finally, hydrophilicity seemed to give substantial contribution in the transport process as well as the mechanical strength of the membrane.

Inhibition Kinetics of Sida rhombifolia L. Extract Toward Xanthine Oxidase by Electrochemical Method Dyah Iswantini; Muammar Yulian; Sri Mulijani; Trivadila Trivadila
Indonesian Journal of Chemistry Vol 14, No 1 (2014)
Publisher : Universitas Gadjah Mada

Sida rhombifolia L. is a traditional medicinal plant that has been known with potential as antigout. The previous research suggested that flavonoids crude extract of S. rhombifolia had an inhibitory activity toward xanthine oxidase by 71% and a spectrophotometric measurement showed that the type of flavonoids crude extract inhibition was a competitive inhibition. The purpose of the research was to investigate the type of inhibition kinetic of S. Rhombifolia’s ethanol extract by electrochemical method and to compare the measurements of linearity and sensitivity between spectrophotometric and electrochemical methods. The results showed that the yield of S. Rhombifolia’s ethanol extract was 9.82% with the inhibitory activity ranging from 13.64% to 82.69% (5.00-200 mg L-1) and IC50 value was 91.15±5.74 mg L-1. Allopurinol as a control showed the inhibitory activity of 15.26-70.95% (0.10-4.00 mg L-1) and IC50 value was 2.45±2.21 mg L-1. Inhibition kinetics of the ethanol extract caused a KM increase and unchange of VMAX. Based on the data, the type of inhibition kinetics was a competitive inhibition, with an inhibitor affinity (α) value of 3.18. Linearity of xanthine oxidase activity assay by electrochemical and spectrophotometric methods showed the range of 0.01-1.00 mM (R2 = 0.978) and 0.05-0.70 mM (R2 = 0.977) respectively. The sensitivity of electrochemical method was reported higher (0.95 μA mM-1) than the spectrophotometric method (0.007 min-1).

TOTAL HYDROGENATION OF BIOMASS-DERIVED FURFURAL OVER RANEY NICKEL-CLAY NANOCOMPOSITE CATALYSTS Rodiansono Rodiansono; Takayoshi Hara; Shogo Shimazu
Indonesian Journal of Chemistry Vol 13, No 2 (2013)
Publisher : Universitas Gadjah Mada

Inexpensive Raney Ni-clay composite (R-Ni/clay) catalysts exhibited excellent activity and reusability in the total hydrogenation of biomass-derived furfural into tetrahydrofurfuryl alcohol under mild conditions. For the Raney Ni-bentonite (R-Ni/BNT) catalysts, the complete reaction was achieved at 393 K, 180 min giving almost 99% yield of tetrahydrofurfuryl alcohol. The R-Ni/BNT catalyst was found to be reusable without any significant loss of activity and selectivity for at least six consecutive runs.

Glucose Oxidase Immobilization on TMAH-Modified Bentonite Ruth Chrisnasari; Zerlina Gabriela Wuisan; Arief Budhyantoro; Restu Kartiko Widi
Indonesian Journal of Chemistry Vol 15, No 1 (2015)
Publisher : Universitas Gadjah Mada

The influence of bentonite modification by tetramethyl ammonium hydroxide (TMAH) on its capability to immobilize glucose oxidase (GOX) was studied. Modification of bentonite was conducted by the adding of 0-5% (v/v) TMAH. The observed results show that the different concentrations of TMAH affect the percentage of immobilized enzyme. The results of this study show that the best concentration of TMAH is 5% (v/v) which can immobilize up to 84.71% of GOX. X-ray diffraction (XRD) and Fourier Transforms Infrared Spectroscopy (FTIR) studies have been carried out to observe the structural changes in bentonite due to TMAH modification. The obtained immobilized GOX show the optimum catalytic activity on reaction temperature of 40-50 °C and pH of 7. The immobilized GOX kinetics at the optimum conditions determined the Km and Vmax value to be 4.96x10-2 mM and 4.99x10-3 mM.min-1 respectively. In addition, the immobilized GOX on TMAH-modified bentonite is stable enough so it could be re-used six times before its activity decreased by 39.44%.

Synthesis and Characterization Superabsorbent Hydrogels of Partially Neutralized Acrylic Acid Prepared Using Gamma Irradiation; Swelling and Thermal Behavior Erizal Erizal; Basril Abbas; Sulistioso Giat Sukaryo; Dhena Ria Barleany
Indonesian Journal of Chemistry Vol 15, No 3 (2015)
Publisher : Universitas Gadjah Mada

A series of superabsorbent hydrogels were synthesized from partially neutralized acrylic acid with varying degree of neutralization (0-1) using gamma radiation. The effects of degree neutralization of acrylic acid on swelling ratio were studied. DSC measurement was performed to understand the type of end products resulting from irradiation. The morphologies of the hydrogels were examined using SEM. The chemical changes of the hydrogels were characterized using FTIR. At optimum conditions (10 kGy, 15 min), the hydrogels with neutralization degree 0.5 exhibited rapid swelling with the highest swelling ratio ~1000 g/g. The results of DSC studies confirmed the possible formation of the type hydrogels from irradiated partially neutralized acrylic acid, and the hydrogels showed large numbers of pores from SEM examination.

Page 3 of 196 | Total Record : 1956

1 2 3 4 5

Filter by Year

2001 2025

Filter By Issues

All Issue Vol 25, No 5 (2025) Vol 25, No 4 (2025) Vol 25, No 3 (2025) Vol 25, No 2 (2025) Vol 25, No 1 (2025) Vol 24, No 6 (2024) Vol 24, No 5 (2024) Vol 24, No 4 (2024) Vol 24, No 3 (2024) Vol 24, No 2 (2024) Vol 24, No 1 (2024) Vol 23, No 6 (2023) Vol 23, No 5 (2023) Vol 23, No 4 (2023) Vol 23, No 3 (2023) Vol 23, No 2 (2023) Vol 23, No 1 (2023) Vol 22, No 6 (2022) Vol 22, No 5 (2022) Vol 22, No 4 (2022) Vol 22, No 3 (2022) Vol 22, No 1 (2022) Vol 22, No 2 (2022) Vol 21, No 6 (2021) Vol 21, No 5 (2021) Vol 21, No 4 (2021) Vol 21, No 3 (2021) Vol 21, No 2 (2021) Vol 21, No 1 (2021) Vol 20, No 6 (2020) Vol 20, No 5 (2020) Vol 20, No 4 (2020) Vol 20, No 3 (2020) Vol 20, No 2 (2020) Vol 20, No 1 (2020) Vol 19, No 4 (2019) Vol 19, No 3 (2019) Vol 19, No 2 (2019) Vol 19, No 1 (2019) Vol 18, No 4 (2018) Vol 18, No 3 (2018) Vol 18, No 2 (2018) Vol 18, No 1 (2018) Vol 17, No 3 (2017) Vol 17, No 2 (2017) Vol 17, No 1 (2017) Vol 16, No 3 (2016) Vol 16, No 2 (2016) Vol 16, No 1 (2016) Vol 15, No 3 (2015) Vol 15, No 2 (2015) Vol 15, No 1 (2015) Vol 14, No 3 (2014) Vol 14, No 2 (2014) Vol 14, No 1 (2014) Vol 13, No 3 (2013) Vol 13, No 2 (2013) Vol 13, No 1 (2013) Vol 12, No 3 (2012) Vol 12, No 2 (2012) Vol 12, No 1 (2012) Vol 11, No 3 (2011) Vol 11, No 2 (2011) Vol 11, No 1 (2011) Vol 10, No 3 (2010) Vol 10, No 2 (2010) Vol 10, No 1 (2010) Vol 9, No 3 (2009) Vol 9, No 2 (2009) Vol 9, No 1 (2009) Vol 8, No 3 (2008) Vol 8, No 2 (2008) Vol 8, No 1 (2008) Vol 7, No 3 (2007) Vol 7, No 2 (2007) Vol 7, No 1 (2007) Vol 6, No 3 (2006) Vol 6, No 2 (2006) Vol 6, No 1 (2006) Vol 5, No 3 (2005) Vol 5, No 2 (2005) Vol 5, No 1 (2005) Vol 4, No 3 (2004) Vol 4, No 2 (2004) Vol 4, No 1 (2004) Vol 3, No 3 (2003) Vol 3, No 2 (2003) Vol 3, No 1 (2003) Vol 2, No 3 (2002) Vol 2, No 2 (2002) Vol 2, No 1 (2002) Vol 1, No 3 (2001) Vol 1, No 2 (2001) Vol 1, No 1 (2001) ARTICLE IN PRESS Article in press More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kab. sleman, Daerah istimewa yogyakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA