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INDONESIA
Jurnal Penelitian Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Farmasi Indonesia Riau
ISSN : 2302187X     EISSN : 26563614     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Jurnal Penelitian Farmasi Indonesia adalah publikasi ilmiah berkala yang terbit dua kali dalam satu tahun (September dan Maret) dan menggunakan sistem peer-riview dalam seleksi makalah. Jurnal Penelitian Farmasi Indonesia menerima naskah publikasi tentang hasil penelitian, survei dan telaah pustaka yang erat kaitanya dengan bidang kefarmasian dan kesehatan.
Arjuna Subject : -
Articles 111 Documents
 8   9   10   11   12 
UJI AKTIVITAS ANTIBAKTERI INFUSA DAUN SIRIH (Piper betle L.) TERHADAP BAKTERI Escherichia coli Hasyrul Hamzah; Amrina Rossada Septilapani; Neni Frimayanti
Jurnal Penelitian Farmasi Indonesia Vol. 10 No. 2 (2021): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v10i2.1434

Abstract

Research has been carried out on the antibacterial activity test of betel leaf infusion against Escherichia coli bacteria by solid dilution method. This study aims to determine the antibacterial activity of betel leaf infusion (Piper betle L.) against Escherichia coli bacteria. Bacterial control used a bacterial suspension dilution of 10-5 with a colony count of 212.33 colonies/mL and the control media showed that the media used was free from contamination. The results of the antibacterial research showed that the infusion of betel leaf had activity in inhibiting the growth of Escherichia coli bacteria at an infusion concentration of 25% with the number of colonies 188.33 colonies/mL, 50% with the number of colonies 160.66 colonies/mL, 75% with the number of colonies 137, 33 colonies/mL and 100% with the number of colonies 106.33 colonies/mL. The results of data analysis with the percentage decrease in the number of betel leaf infusion colonies against Escherichia coli bacteria that the higher the betel leaf infusion concentration, the less the number of bacterial colony growth, there was a difference marked by the difference in the number of bacterial colonies between control bacteria and the number of bacterial colonies at each concentration infusion.
T Tingkat Pengetahuan Masyarakat Tentang Penyakit Tuberkulosis di Kelurahan Rintis Pekanbaru: Level of Public Knowledge about Tuberculosis at Rintis Village Pekanbaru erniza - pratiwi; Nouval Zamra
Jurnal Penelitian Farmasi Indonesia Vol. 11 No. 1 (2022): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v11i1.1414

Abstract

Research on the level of public knowledge about tuberculosis was conducted in Rintis Village, Pekanbaru City. This study aims to determine the level of public knowledge about tuberculosis in Rintis Village, Pekanbaru City. This study uses an observational method that is descriptive analytic using a cross sectional design through filling out questionnaires. The sampling technique in this study was carried out by non probability sampling with a purposive sampling method. The sample that became this study was 100 respondents who met the inclusion criteria. Research respondents who met the inclusion criteria were given a questionnaire which was then filled in by the respondent. Then the data is processed and analyzed by researchers. Based on the results of the study, it shows that people who have high knowledge are as much as 47%, people who have sufficient knowledge are as many as 32% and people who have low knowledge are as much as 21%. High knowledge is dominated by respondents with an age range of 56-65 years, female gender, high education (college) and secondary, and civil servant occupations.
PENGARUH MEDIA EDUKASI E-BOOKLET TERHADAP TINGKAT PERILAKU TENAGA TEKNIS KEFARMASIAN PADA PENGGALIAN INFORMASI SWAMEDIKASI COMMON COLD Septi Muharni; Fadila Toha; Fina Aryani; Husnawati
Jurnal Penelitian Farmasi Indonesia Vol. 11 No. 1 (2022): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v11i1.1538

Abstract

Self-medication service is a high service practice carried out by pharmaceutical technical personnel, one of which is the common cold self-medication service. This demands a fairly high TTK role, one of which is in information research. The purpose of this study was to see the effect of providing educational media for TTK level e-booklets on common cold self-medication information. This research is quasi-experimental research: non-equivalent control group design using non-probability sampling method with purposive sampling technique. The sample in this study was 100 TTK who were registered with the Regional Board of the Indonesian Pharmacists Association of Riau Province and worked in pharmacies. The data were analyzed by marginal homogeneity test with significant results in the provision of educational media e-booklets on the level of TTK behavior in the treatment group during pre-test and post-test with p value = 0,011 (p <0.05). Based on the results of this study, it is said that presenting e-booklet educational media can increase TTK in Riau Province on the behavior of self-medication information on common cold.
Explaining the Knowledge and Attitudes of Medan City Residents in Using Telemedicine During the COVID-19 Pandemic Nadroh Br Sitepu; Tasya Sevrina
Jurnal Penelitian Farmasi Indonesia Vol. 11 No. 1 (2022): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v11i1.1652

Abstract

Coronavirus disease 2019 (COVID-19) is a transmissible respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Governments should encourage telemedicine, the use of technology that combines information and communication with medical expertise to deliver health services, and the ability to diagnose and administer medical care without being held in confined spaces or remote locations. We are calling on the public to start consultations on. Study this aim for knowing description knowledge and attitude the people of Medan City in utilising telemedicine during the COVID-19 pandemic. Method study character survey descriptive, taking sample use method purposive sampling with amount sample as many as 99 respondents. Research results show that the level of knowledge of the people of Medan City against telemedicine with categories good (86.9%), enough good (10.1%), and less good (3%). Attitude level the people of Medan City utilise telemedicine with categories good (66.7%), enough good (32.3%), and less good (1%). The study this is description level knowledge and attitude the people of Medan City are in category good.
FORMULASI MINYAK ANGIN AROMATERAPI MINYAK JERUK KASTURI (Citrofortunella microcarpa) Wira Noviana Suhery; Dinda Wijayaningsih; Ratna Fitry Yenny
Jurnal Penelitian Farmasi Indonesia Vol. 11 No. 1 (2022): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v11i1.1744

Abstract

Inovasi terhadap bentuk sediaan dan aroma minyak angin dilakukan agar dapat memperluas pasar minyak angin, termasuk kalangan remaja dan anak muda. Inovasi minyak angin yang lebih modern, baik terhadap aroma khasnya serta kemasannya tanpa mengurangi efektivitas farmakologi. Penelitian ini bertujuan untuk memformulasikan minyak angin aromaterapi dengan minyak jeruk kasturi sebagai pengaroma dan menevaluasi sifat fisik minyak angin, dan menguji tingkat kesukaan terhadap minyak angin yang dibuat. Penelitian ini merupakan penelitian eksperimental yang memformulasi minyak angin menggunakan 3 konsentrasi minyak jeruk kasturi (4%, 6%, dan 10%) sebagai aromaterapi. Uji tingkat kesukaan terhadap produk dilakukan pada 100 panelis dengan parameter organoleptis sediaan terhadap warna, bau, dan sensasi di kulit. Hasil menunjukkan bahwa F3 (10%) memiliki sifat fisik baik dan memiliki tingkat kesukaan yang tinggi diantara 100 panelis.
TINGKAT PENGETAHUAN DAN SIKAP MAHASISWA FARMASI DAN NON FARMASI TERHADAP PENGGUNAAN TABIR SURYA Hesti Hesti; Ida Ida; Tajuddin Abdullah
Jurnal Penelitian Farmasi Indonesia Vol. 11 No. 2 (2022): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v11i2.1435

Abstract

Indonesia is a tropical country that is blessed with an abundance of sunlight which causes the importance of skin protection. One of them is the use of sunscreen. The correct application of sunscreen greatly affects its effectiveness in providing protection. Knowledge is one of the factors that support the use of sunscreen. One of the fields studied by pharmacy students is cosmetics. This study was conducted to compare the level of knowledge and attitudes of pharmacy and non-pharmaceutical students towards the use of sunscreen. This study is a descriptive study using a cross sectional design. Sampling in this study using the table Isaac and Michael. The data collection technique used a questionnaire that was filled out online consisting of 14 questions about knowledge and 21 questions about attitudes. The results showed that pharmacy and non-pharmaceutical students had a bad level of knowledge with scores of 17 and 16 respectively. Meanwhile, the attitude level of the two majors was good with scores of 39 and 38, respectively. After the Mann Whitney test was carried out, there was a significant difference at the level of knowledge between pharmacy and non-pharmaceutical students (P=0.000). However, at the attitude level, there was no significant difference (P=0.578). These results indicate that pharmacy students have a better level of knowledge than non-pharmacy students, although they are still in the same category, namely bad. So education related to sunscreen needs to be done to improve this condition.
PENGARUH PEMBERIAN EKSTRAK ETANOL HERBA KROKOT (Portulaca grandiflora) TERHADAP EFEK ANALGETIK PADA MENCIT (Mus musculus) Bida cincin Kirana; Antonius Budiawan
Jurnal Penelitian Farmasi Indonesia Vol. 11 No. 2 (2022): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v11i2.1536

Abstract

Portulaca grandiflora diketahui memiliki kandungan metabolit sekunder flavonoid, polisakarida, sterol, karotenoid, dan asam polifenol. Kandungan tersebut memiliki kemiripan dengan Portulaca oleracea. Portulaca oleracea mengandung flavonoid yang memiliki aktivitas antiinflamasi dengan mekanisme menghambat enzim COX (Cyclooxygenase) dan enzim lipoxygenase. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol herba krokot (P. grandiflora) terhadap efek analgetik. Aktivitas analgetik diuji menggunakan metode hot plate dengan suhu 50-55°C. Pembagian kelompok uji antara lain kelompok kontrol negatif (diberi perlakuan suspensi CMC Na), kelompok kontrol positif (diberi ibuprofen 26 mg/kgBB), kelompok ekstrak dosis 1 (diberi ekstrak etanol herba krokot dosis 200 mg/kgBB), kelompok ekstrak dosis 2 (diberi ekstrak etanol herba krokot dosis 400 mg/kgBB), kelompok ekstrak dosis 3 (diberi ekstrak etanol herba krokot dosis 800 mg/kgBB). Hasil uji menunjukkan bahwa ekstrak etanol krokot (P. grandiflora) memiliki aktivitas analgetik pada mencit (Mus musculus) dengan dengan rata-rata total respon 3,3±1,5 untuk dosis 800 mg/kgBB, 6,0±0,0 untuk dosis 400 mg/kgBB, dan 6,5±4,0 untuk dosis 200 mg/kgBB yang seluruhnya berbeda signifikan dengan kontrol negatif pada menit ke-60.
S SINTESIS DAN UJI AKTIVITAS ANTIBAKTERI SENYAWA 3ꞌ-BROMO-4-METOKSI KALKON TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli Rahma Dona; Haiyul Fadhli; Adel Zamri; Winda Tria Safitri; Abdi Wira Septama
Jurnal Penelitian Farmasi Indonesia Vol. 11 No. 2 (2022): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v11i2.1547

Abstract

Chalcone is a flavonoid derivative that has a variety of interesting biological activities. One of the compounds suspected of being an antibacterial agent is chalcone. The properties of chalcone compounds depend on the substituents that depend on the two aromatic rings, such as Cl, Br, OH groups and so on. The purpose of this study was to synthesize chalcone analogue compounds and determine the potential of these analog compounds as antibiotics. In this research, a chalcone analogue compound has been successfully synthesized, namely 3ꞌ-Bromo-4-methoxy-chalcone through the stirring method using KOH catalyst, ethanol solvent. The results of the synthesis carried out by recrystallization and the yield obtained were 64 %. Identification of compounds that have been carried out by TLC test, melting point, and HPLC analysis. The structure of the compound was characterized by UV-Vis spectroscopy, FTIR and 1H NMR, indicating that the analogue chalcone compound has a structure as expected. Testing the activity of chalcone analogue compounds was carried out on Staphylococcus aureus and Escherichia coli at a concentration of 1%, 5%, 10% and 20% test solutions. The test results showed that the antibacterial activity of the compound 3ꞌ-Bromo-4-methoxy-chalcone was categorized as weak.
Aktivitas Antioksidan AKTIVITAS ANTIOKSIDAN DARI EKSTRAK ETANOL KULIT BATANG SUKUN (Artocarpus altilis (Parkinson ex F.A.Zom) Fosberg : AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL KULIT BATANG SUKUN (Artocarpus altilis (Parkinson ex F.A.Zom) Fosberg Syilfia Hasti; Raoda makbul
Jurnal Penelitian Farmasi Indonesia Vol. 11 No. 2 (2022): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v11i2.1739

Abstract

Artocarpus altilis (Parkinson ex F.A.Zom) Fosberg is also widely used in traditional medicine. People living in  Indonesia, use the fruit flesh as a tonic for the liver and use decoction of the leaves to treat to treat liver cirrhosis, hypertension, and diabetes. Research has been done on antioxidant activity  using DPPH method on ethanol extract of breadfruit bark (Artocarpus altilis (Parkinson ex F.A.Zom) Fosberg using 2-Diphenyl-1-picrylhydrazyl as a free radical. Antioxidant activity test with comparison of vitamin C. The parameter measured is the absorbance using a 96 well Microplate Reader (Epoch®), then the IC50 value is calculated. This study aimed to determine the antioxidant activity of the ethanolic extract of the breadfruit (Artocarpus altilis (Parkinson ex F.A.Zom) stem bark extract. The antioxidant test results of the ethanol extract of breadfruit stem bark (Artocarpus altilis (Parkinson ex F.A.Zom) Fosberg had an IC50 value of 133.98 µg/mL with the medium category.
FORMULASI DAN EVALUASI FISIK MASKER GEL PEEL OFF EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus Polyrhizus) Nofriyanti - Nofriyanti; wira noviana suhery; nesa agistia; wildan khairi muhtadi
Jurnal Penelitian Farmasi Indonesia Vol. 11 No. 2 (2022): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v11i2.1741

Abstract

Kulit adalah organ penting dari tubuh kita, umumnya wanita menginginkan kulit yang bersih dan cerah terutama pada kulit wajah, salah satu sediaan kosmetik untuk menjaga kebersihan dan perawatan kulit wajah adalah masker wajah. Jenis masker wajah yang praktis digunakan yaitu masker gel yang setelah kering dapat langsung dikelupas atau biasa dikenal dengan sebutan masker gel peel off. Masker gel peel off merupakan masker gel yang mudah dalam penggunaannya, setelah kering masker dapat langsung dilepas dan menghilangkan sisa-sisa kotoran yang menempel pada permukaan kulit wajah. Penelitian ini bertujuan untuk memformulasi sediaan masker gel peel off dengan variasi konsentrasi F1 (3%), F2 (5%) dan F3 (7%), yang memiliki stabilitas fisik yang baik dari ekstrak kulit buah naga merah, serta menegetahui variasi konsentrasi zat aktif manakah yang lebih baik. Dari hasil yang didapatkan selama empat minggu penyimpanan didapatkan F1, F2, dan F3 homogen pada minggu pertama dan kedua penyimpanan, namun pada minggu ketiga sampai keempat penyimpanan sediaan tidak homogen lagi karena membentuk dua bagian yaitu air dan basis, pemeriksaan pH pada sediaan menunjukan bahwa pH masker gel selama empat minggu penyimpanan menunjukan penurunan pH yaitu basis dengan rentang 6,48-5,38, F1 dengan rentang 5,22-4,71, F2 dengan rentang 5,19-4,91, dan F3 dengan rentang 5,06-4,79 tetapi masih dalam range pH kulit yaitu 4,5-6,5. Untuk daya sebar dan waktu mengering tidak masuk dalam syarat masing-masing evaluasi karena sediaan tidak homogen selama penyimpanan empat minggu.

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