Garuda - Garba Rujukan Digital

Update Manajemen Preeklamsia dengan Komplikasi Berat (Eklamsia, Edema Paru, Sindrom HELLP) Nuswil Bernolian; Wim T Pangemanan; A. Kurdi Syamsuri; M. Hatta Ansyori; Putri Mirani; Peby Maulina Lestari; Abarham Martadiansyah; Cindy Kesty
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 1 Maret 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v6n1.402

Tujuan: Seiring dengan bertambahnya insidensi preeklamsia dengan komplikasi berat, manajemen yang adekuat diperlukan. Penulisan artikel ini bertujuan untuk memaparkan update manajemen preeklamsia dengan komplikasi berat (eklamsia, edema paru, dan sindrom HELLP).Metode: Tinjauan pustaka (literature review) dengan menggunakan 15 referensi antara tahun 2011–2020.Hasil: Manajemen preeklamsia dengan komplikasi berat membutuhkan pendekatan multidisiplin, medikamentosa (kalsium 1,5–2 gram/hari; aspirin dosis rendah 75–150 mg/hari; MgSO4 dengan dosis awal 4–6 gram IV dan pemeliharaan 1-2 gram/jam hingga 24 jam pascasalin; kortikosteroid; antihipertensi seperti labetalol, hidralazin, nifedipin, natrium nitroprusside, nitrogliserin), dan non-medikamentosa (olahraga, pembatasan cairan). Sementara itu, prinsip penanganan awal eklamsia, yaitu D (Dangers) – R (Response) – S (Send for Help) – A (Airway) – B (Breathing) – C (Compressions) – D (Defibrillation). Adapun manajemen obstetri pada kasus preeklamsia dengan gejala berat, yaitu manajemen ekspektatif dan persalinan (spontan ataupun seksio sesaria).Kesimpulan: Tatalaksana yang cepat dan tepat pada kasus preeklamsia dengan komplikasi berat sangat diperlukan untuk mengurangi morbiditas pada ibu dan janin. Manajemen kasus preeklamsia dengan gejala berat berupa manajemen ekspektatif dan persalinan (spontan ataupun seksio sesaria).Update on Management of Preeclampsia with Severe Features (Eclampsia, Pulmonary Edema, HELLP Syndrome)AbstractObjective: As the incidence of preeclampsia with severe features increases, adequate management is required. The purpose of this review is to present an update on the management of preeclampsia with severe features (eclampsia, pulmonary edema, and HELLP syndrome).Method: Literature review using 15 references between 2011–2020.Results: Management of preeclampsia with severe features requires a multidisciplinary, medical approach (calcium 1.5–2 g/day; low-dose aspirin 75–150 mg/day; magnesium sulfate at an initial dose of 4–6 g IV and maintenance 1-2 g/hour to 24 hours postpartum; corticosteroids; antihypertensives such as labetalol, hydralazine, nifedipine, sodium nitroprusside, nitroglycerin) and non-medical (exercise, fluid restriction). Meanwhile, the principles of early management of eclampsia, namely D (Dangers) – R (Response) – S (Send for Help) – A (Airway) – B (Breathing) – C (Compressions) – D (Defibrillation). The obstetric management in cases of preeclampsia with severe features is expectant management and delivery (spontaneous or cesarean section).Conclusion: Prompt and appropriate management of cases of preeclampsia with severe features is needed to reduce maternal and fetal morbidity. Management of preeclampsia cases with severe features is expectant management and delivery (spontaneous or cesarean section).Key words: preeclampsia, eclampsia, HELLP syndrome, severe.

Nyeri Haid dan Kista Endometriosis pada Remaja Ruswana Anwar; Jaeni Pringgowibowo
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 1 Maret 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v6n1.458

Tujuan: Kegiatan pengabdian masyarakat ini bertujuan untuk untuk menganalisis tingkat pengetahuan dismenore yaitu dismenore primer dan sekunder dengan memberikan solusi melalui penyuluhan di Kota Bandung.Metode: Kegiatan pertama adalah kunjungan dan wawancara dengan pasien wanita di UPT Puskesmas Garuda Kota Bandung. Seusai acara, kami melakukan angket dan diskusi dengan siswa SMAN 24 Bandung dengan pendekatan konseling, serta membagikan booklet berjudul “mengenal nyeri haid normal” dan tayangan video. Hasil: Sikap responden 86,7% siswa mengalami ketidaknyamanan selama menstruasi: 1-2 hari sebelum dan 1-2 hari selama menstruasi; dan 63,9% siswa ditangani dengan istirahat. Pengetahuan responden setelah diberikan penyuluhan sebanyak 98,5% menjawab benar pengertian dismenore; 100% menjawab tipe dismenore adalah primer dan sekunder; 94% menjawab salah satu pengobatan komplementer saat nyeri haid kompres dengan air hangat; 100% menjawab penyakit yang menyebabkan dismenore adalah endometriosis; 97% menjawab gejala khas endometriosis adalah nyeri haid saat menstruasi.Kesimpulan: Terdapat peningkatan pengetahuan setelah diberikan penyuluhan tentang nyeri haid (dismenore) meningkat, terutama pengetahuan tentang endometriosis dan tipe dismenore primer maupun sekunder, sehingga dapat disimpulkan upaya pemberian penyuluhan sangat penting untuk menambah pengetahuan dan meningkatkan kesadaran mengenai upaya preventif dalam tata kelola penanganan nyeri haid.Menstrual Pain and Endometriosis Cysts in AdolescentsAbstractObjective: This community service activity aims to analyze the level of knowledge of dysmenorrhea, namely primary and secondary dysmenorrhea by providing solutions through counseling in the city of Bandung. Methods: The first activity was visits and interviews with female patients at UPT Puskesmas Garuda Bandung City. After the event, we conducted a questionnaire and discussion with students of sman 24 bandung with a counseling approach and distributed a booklet entitled “knowing normal menstrual pain” and video shows. Result: The attitude of respondents 86.7% of students experienced discomfort during menstruation: 1-2 days before and 1-2 days during menstruation; and 63.9% of students were treated with rest. Knowledge of respondents after being given counseling as much as 98.5% answered correctly the meaning of dysmenorrhea; 100% answered that the type of dysmenorrhea was primary and secondary; 94% answered one of the complementary treatments when menstrual pain was compressed with warm water; 100% answered that the disease that causes dysmenorrhea is endometriosis; 97% answered that the typical symptom of endometriosis is menstrual pain during menstruation. Conclusions: There is an increase in knowledge after being given counseling about menstrual pain (dysmenorrhea), especially knowledge about endometriosis and the types of primary and secondary dysmenorrhea, so it can be concluded that the effort to provide counseling is very important to increase knowledge and increase awareness about preventive efforts in the management of menstrual pain management.Key words: dysmenorrhea, menstrual pain, endometriosis.

Pengaruh Spektrum Plasenta Akreta terhadap Luaran Maternal di RSUP Dr. Hasan Sadikin Bandung Wati Puspitasari; Hadi Susiarno; Akhmad Yogi Pramatirta
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 1 Maret 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v6n1.468

Tujuan: Penelitian bertujuan untuk menganalisis pengaruh spektrum plasenta akreta terhadap volume perdarahan, infeksi daerah operasi, dan lama hari rawat.Metode: Metode yang digunakan adalah analitik observasional dengan desain kohor retrospektif. Data diambil dengan meninjau rekam medis. Pengambilan sampel untuk kedua kelompok diambil dengan menggunakan teknik purposive sampling melalui penetapan kriteria inklusi dan ekslusi. Kelompok pertama subjek dengan spektrum plasenta akreta yang tercatat di dalam rekam medik dalam kurun waktu dari tahun 2016 – 2021, dan kelompok kedua subjek dengan non spektrum plasenta akreta diambil dengan perbandingan 1:2 terhadap kelompok pertama. Data dianalisis menggunakan uji Fisher Exact dan Regresi Logistik Ganda dengan nilai p<0,05 dianggap bermakna secara statistik.Hasil: Hasil penelitian menunjukkan bahwa terdapat pengaruh yang signifikan (p<α) terhadap volume perdarahan (p=0,025), infeksi daerah operasi (p=0,025), dan lama hari rawat (p<0,001). Peluang spektrum plasenta akreta terhadap terjadinya volume perdarahan sebesar 3,58 kali, infeksi daerah operasi 4,03 kali, dan lama hari rawat 50,09 kali. Meskipun pengaruh spektrum plasenta akreta secara multivariat tidak dominan terhadap volume perdarahan dan infeksi daerah operasi namun berpengaruh secara bermakna terhadap lama hari rawat.Kesimpulan: Terdapat pengaruh spektrum plasenta akreta terhadap volume perdarahan, infeksi daerah operasi, dan lama hari rawat.The Effect of Placenta Accreta Spectrum on Maternal Outcomes at Hasan Sadikin Bandung General HospitalAbstractObjective: The aim of this study was to analyze the effect of placenta accreta spectrum on bleeding volume, surgical site infection, and length of stay.Methods: This was an observational analytic study with a retrospective cohort design. Data were taken by reviewing medical records with samples divided into two groups. Sampling for both groups was taken using a purposive sampling technique, the samples were selected by establishing inclusion and exclusion criteria. The first group of subjects with the placenta accreta spectrum recorded in the medical record in the period from 2016 – 2021, and the second group of subjects with non-spectrum placenta accreta was taken in a ratio of 1:2 to the first group. Data were analyzed using the Fisher Exact test and Multiple Logistic Regression with a value of p <0.05 which was considered statistically significant.Result: The results showed there was a significant effect (p<α) on bleeding volume (p=0.025), surgical site infection (p=0.025), and length of stay (p<0.001). The probability of placenta accreta spectrum for the occurrence of bleeding volume is 3.58 times, 4.03 times for surgical site infection, and 50.09 times for length of stay. Even though the placenta accreta spectrum multivariate test did not show a significant effect on bleeding volume and surgical site infection, but has a significant effect on length of stay.Conclusion: There was an effect of placenta accreta spectrum on bleeding volume, surgical site infection, and length of stay.Key words: bleeding, length of stay, maternal outcome, surgical site infection, placenta accreta spectrum.

Hernia Umbilikalis Post Sectio Sesarea pada Kehamilan Ganda: Sebuah Laporan Kasus Fenyta Christyani; Sigit Pradono Diptoadi
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 1 Maret 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v6n1.338

Tujuan: Mengetahui faktor risiko dan mekanisme terjadinya hernia umbilikalis pada pasien wanita post partumMetode:Teknik pengumpulan data melalui wawancara, pemeriksaan, observasi, serta dokumentasiKasus: Perempuan G2P1A0 hamil 35-36 minggu, bekas sectio sesarea, janin ganda intrauterine dengan rencana sectio sesarea. Riwayat ANC rutin dan tidak ditemukan kelainan. Dua hari setelah operasi section sesarea pasien mengeluhkan mual, muntah, dan ditemukan massa pada regio umbilikalis dengan konsistensi keras, immobile, terdapat nyeri tekan dan suara bising usus. Luka operasi baik. Pada pemeriksaan USG abdomen tampak gambaran hernia ventralis paramedian kanan abdomen. Pasien kemudian dilakukan operasi laparotomi hernioraphyDiskusi: Hernia umbilikal merupakan penonjolan usus yang berlokasi dekat umbilikus. Hal ini disebabkan oleh peningkatan tekanan intraabdominal dan kelemahan dari dinding perut. Terdapat beberapa faktor risiko yang mencetuskan. Faktor risiko pada kasus ini adalah obesitas, riwayat operasi sectio sesarea, dan kehamilan. Obesitas menyebabkan peningkatan tekanan intraabdominal, terjadi stress mekanik yang mengakibatkan gangguan dari metabolisme kolagen. Kesimpulan: Pada wanita dengan kehamilan ganda, obesitas dan riwayat operasi sebelumnya menjadi faktor risiko terjadinya kejadian hernia umbilikal. Umbilical Hernia Post Sectio Caesarea in Multiple Pregnancies: A Case ReportAbstractObjective: To know the risk factors and mechanism of umbilical hernia in post partum female patientsMethods:Techniques through interviews, examinations, observations, and documentationCase: G2P1A0 woman 35-36 weeks, former cesarean section with intrauterine multiple fetus with planned cesarean section. A history of routine ANC and no abnormalities were found. Two days after cesarean section the patient complained of nausea, vomiting, and found a mass in the umbilical region with a firm consistency, immobile, tenderness and bowel sounds. The surgical wound is good. On ultrasound examination of the abdomen showed a picture of the right paramedian ventral hernia of the abdomen. The patient then underwent laparotomy for hernioraphyDiscussion: Umbilical hernia is a protrusion of the intestine that is located near the umbilicus. It is caused by increased intraabdominal pressure and weakness of the abdominal wall. There are several risk factors that trigger it. The risk factors in this case were obesity, history of cesarean section, and pregnancy. Obesity causes an increase in intraabdominal pressure, mechanical stress occurs which results in disruption of collagen metabolism. Conclusion: In women with multiple pregnancies, obesity and a history of previous surgery are risk factors for the occurrence of umbilical herniaKey words: Umbilical hernia, cesarean section, multiple pregnancies

Front Cover, Editorial Team, Table of Contents, and Back Cover obgyn jurnal
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 1 Maret 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar

Hubungan Antara Indeks Massa Tubuh dan Paritas dengan Inkontinensia Urin Tipe Tekanan dan Desakan pada Lansia Farahdiba Aisyah Putri Ridwan; Sadakata Sinulingga; Amir Fauzi; Hadrians Kesuma Putra; Ridwan Abdullah Putra
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 2 Juli 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v6.n2.524

Tujuan: Mengetahui hubungan antara IMT dan paritas dengan SUI dan UUI pada lansia. Metode: Penelitian observasional analitik dengan pendekatan desain cross sectional, penelitian ini menggunakan data primer yang diperoleh melalui wawancara menggunakan kuesioner untuk diagnosis inkontinensia urin (QUID).Hasil: Dari 64 responden lansia perempuan terdapat 26 yang mengalami SUI (40,6 %) dan 14 yang mengalami UUI (21,9%), terdapat hubungan yang signifikan antara IMT dengan SUI (p<0,05). Selain itu, paritas memiliki hubungan yang tidak signifikan dengan SUI (P>0,05, UUI memiliki hubungan yang tidak signifikan dengan IMT dan paritas (p>0,05). Kesimpulan: Terdapat hubungan yang signifikan antara IMT dan SUI.Kata kunci: IU, IMT, Paritas, Perempuan Lansia Association between Body Mass Indeks and Parity with Stress and Urgency Urinary Incontinence in the Elderly AbstractObjective: To find out the association between BMI and parity with SUI and UUI in the elderly. Method: This research was an analytic observational study with a cross sectional approach, This study used primary data obtained through interviews and uses the Questionnaire for Urinary Incontinence Diagnosis (QUID). Results: Data from 64 female elderly respondents showed that there was 26 female elderly with SUI (40,6%) and 14 with UUI (21,9%), there is a significant association between BMI for SUI (p<0,05). In addition, parity had no significant association with SUI (p>0,05). Meanwhile, UUI has no significant relationship with BMI and parity (p>0,05).Conclution: There was a significant association between BMI and SUI.Key words: UI, BMI, Parity, Elderly Women

Effect Of Corona Virus Disease 2019 (Covid-19) on the Incidence of Preterm Birth And Asphyxia at Banjar Regional General Hospital Kulfa Sholehah; Akhmad Yogi Pramatirta; Firman F. Wirakusumah
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 2 Juli 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v6.n2.490

Objective: This study aims to determine and analyze the effect of Corona Virus Disease (Covid-19) on the incidence of preterm birth and asphyxia at Banjar Regional General Hospital. Method: This was an analytical observational study with a retrospective cohort approach. The type of data involved in this study was secondary data derived from medical record with a total sample of 59 women in labor diagnosed with Covid-19 and 513 women in labor who were not diagnosed with Covid-19.Results : The result of the study showed that there was a significant difference in the incidence of preterm birth between women in labor diagnosed with Covid-19 and those who were not diagnosed with Covid-19 (ρ value=0.000 or ρ<0.05). Regarding the incidence of asphyxia, the result showed that there was no difference in the incidence of asphyxia between infants born to women diagnosed with Covid-19 and those born to women who were not diagnosed with Covid-19, with a ρ value of 0.523 or ρ>0.05. Women diagnosed with Covid-19 were at risk of giving birth to premature infants 5.308 times compared to women not diagnosed with Covid-19. The OR of the incidence of preterm birth was 5.308 with a 95% CI of 3.035-9.281. Furthermore, based on the statistical test result, it was revealed that Covid-19 had a low effect on the incidence of asphyxia with the OR value of 0.839 and a 95% CI of 0.489-1.439.Conclusion: Based on the results of the study, it can be concluded that there was an effect of Covid-19 just on the incidence of preterm birth.Pengaruh Corona Virus Disease 2019 (Covid-19) terhadap Kejadian Prematur dan Asfiksia di RSUD Kota BanjarAbstrak Tujuan: Penelitian ini mengukur dan menganalisis pengaruh Corona Virus Disease (Covid-19) terhadap kejadian prematur dan asfiksia di RSUD Kota Banjar. Metode: Penelitian berupa analitik observasi dengan pendekatan kohor retrospektif. Jenis data dalam penelitian ini adalah data sekunder dari rekam medis dengan jumlah sampel menggunakan total sampel yaitu 59 ibu bersalin dengan Covid-19 dan 513 ibu bersalin tidak dengan Covid-19.Hasil: Hasil penelitian menunjukkan terdapat perbedaan yang bermakna kejadian prematur pada Ibu Covid-19 dengan ibu yang tidak terdiagnosis Covid-19 (nilai ρ0.000) yang artinya p0.05. Ibu dengan Covid-19 berisiko melahirkan bayi prematur 5.308 kali dibandingkan pada ibu yang tidak terdiagnosis Covid-19, nilai OR kejadian prematur 5.308 dengan IK 95% 3.035-9.281. Dan dari hasil uji statistik diperoleh hasil yaitu Covid-19 berpengaruh rendah terhadap kejadian asfiksia dengan hasil uji statistik nilai OR 0.839 dengan IK 95% 0.489-1.439. Kesimpulan: Dari hasil penelitian dapat disimpulkan bahwa terdapat pengaruh Covid-19 terhadap kejadian prematur.Kata kunci: Asfiksia, Covid-19, Prematur

Perbandingan Faktor Risiko antara Pertumbuhan Janin Terhambat Onset Dini dan Lambat di RSUD Dr. Moewardi Prilla Firsty Prasetyo Putri; Muhammad Adrianes Bachnas; Nutria Widya Purna Anggraini; Abdurahman Laqif
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 2 Juli 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v6.n2.459

Tujuan: Mengetahui perbandingan faktor risiko antara pertumbuhan janin terhambat onset dini dan lambat di RSUD Dr. Moewardi.Metode: Penelitian observasional analitik dengan pendekatan cross sectional menggunakan data sekunder rekam medis ibu dengan pertumbuhan janin terhambat di RSUD Dr. Moewardi mulai 1 Januari 2020–31 Desember 2021. Pengambilan data menggunakan teknik total sampling, Data diolah menggunakan SPSS dan dianalisis menggunakan uji univariat, kemudia bivariat yaitu uji Chi Square.Hasil: Hasil analisis bivariat menunjukkan bahwa tidak terdapat perbedaan bermakna pada variabel usia, paritas, Indeks Massa Tubuh (IMT), pekerjaan ibu, hipertensi, preeklamsi, diabetes melitus, anemia, asma antara pertumbuhan janin terhambat onset dini dan onset lambat (p>0,05).Kesimpulan: Tidak terdapat perbedaan yang bermakna pada usia ibu, paritas, Indeks Massa Tubuh (IMT), pekerjaan ibu, preeklamsi, hipertensi, diabetes melitus, anemia, asma antara kejadian pertumbuhan janin terhambat onset dini dan lambat di RSUD Dr. Moewardi.Comparison of Risk Factor For Early and Late Onset Intrauterine Growth Restriction in RSUD Dr. MoewardiAbstract Objective: To find out the comparison of risk factors between early-onset and late onset intrauterine growth restriction at RSUD Dr. Moewardi.Method: This research is an analytical observational with a cross sectional approach was done by using medical records of pregnant woman with intrauterine growth restriction at RSUD Dr. Moewardi from January 1, 2020– December 31, 2021. Data was collected using a total sampling technique. And processed by SPSS then analyzed using univariate test, and Chi Square test.Results: The results of bivariate analysis showed that there was no significant differences of age, maternal employment, parity, Body Mass Index (BMI), maternal employment, hypertension, preeclampsia, diabetes mellitus, anemia, asthma between early-onset and late-onset with intrauterine growth restriction (p>0,05).Conclusion: There were no significant differences of maternal age, parity, Body Mass Index (BMI), preeclampsia, maternal employment, hypertension, diabetes mellitus, anemia, asthma between early and late onset intrauterine growth restriction at RSUD Dr. Moewardi.Key words: Risk Factor, Intrauterine Growth Restriction, Early Onset, Late Onset

Effect of Curcumin towards Metabolic Disturbance Parameters in Patient with PCOS: A Systematic Review and Meta-Analysis of Clinical and Preclinical Randomized Controlled Trials Angeline Ekafentie; Nicolas Daniel Widjanarko; Yuliana Yosephine; Mutiara Riani
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 2 Juli 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v6.n2.484

Objective: Polycystic Ovarian Syndrome (PCOS) is a gynecologic and endocrine disorder with metabolic disturbances and infertility as the most common long-term consequences. Curcumin comes up as one of the alternative herbal remedies in PCOS treatment options. This study aimed to investigate the therapeutic effect of curcumin on metabolic disturbance parameters in PCOS patients and PCOS-modeled rats. Method: A systematic search of eligible studies was done using PubMed, Google Scholar, EBSCO-Host, and ProQuest according to the PRISMA 2009 guideline. We further assessed for risk of bias using SYRCLE’s risk of bias tool for preclinical studies and The Cochrane risk of bias assessment tool for the clinical studies. We used Review Manager (version 5.4) with random effect model to obtain a pooled mean difference with 95% CIs. Results: Five preclinical studies and three clinical studies were selected and pooled. The significant decrease in the level of Fasting Plasma Glucose (FPG), Fasting Insulin (FI), lipid profile, and Homeostatic Model of Insulin Resistance (HOMA-IR) value, and a significant increase in Quantitative Insulin-Sensitivity Check Index (QUICKI) value found in preclinical studies. The result for clinical studies showed a significantly decreased HOMA-IR values (SMD=-0.36, p=0.001), FPG level (SMD=-3.32, p=0.0001), Serum Insulin level (SMD=-1.47, p=0.002), and increased QUICKI value (SMD=0.01, p=0.006). Conclusion: Curcumin offers a substantial effect on metabolic disturbance parameters in PCOS patients and could be an alternative promising treatment for PCOS patients in the future.Pengaruh Kurkuma terhadap Parameter Gangguan Metabolik pada Pasien SOPK: Tinjauan Sistematis dan Meta-Analisis Uji Acak Preklinis dan Klinis TerkontrolAbstrakTujuan: Sindrom Ovarian Polikistik (PCOS) merupakan suatu kelainan ginekologi dan endokrin dengan gangguan metabolisme dan infertilitas sebagai konsekuensi jangka panjang yang paling umum ditemukan. Kurkumin muncul sebagai salah satu pengobatan herbal alternatif dalam pilihan terapi PCOS. Penelitian ini bertujuan untuk menyelidiki efek terapeutik kurkumin terhadap parameter gangguan metabolik pada pasien PCOS dan model tikus yang mengalami PCOS.Metode: Penelitian ini dilakukan dengan mencari studi penelitian yang memenuhi syarat menggunakan PubMed, Google Scholar, EBSCO-Host, dan ProQuest mengikuti PRISMA 2009. Penilaian risiko bias studi menggunakan SYRCLE’s Risk of Bias Tool untuk penelitian preklinis dan The Cochrane Risk of Bias Assessment Tool untuk penelitian klinis. Sintesis kuantitatifmenggunakan Review Manager (versi 5.4) dengan random effect model untuk mendapatkan pooled mean difference dengan interval kepercayaan 95%.Hasil: Sebanyak lima studi penelitian preklinis dan tiga studi penelitian klinis memenuhi kriteria. Terdapat penurunan signifikan kadar gula darah puasa, insulin puasa, profil lipid, dan nilai HOMA-IR, serta peningkatan nilai QUICKI pada studi preklinis. Pada studi klinis menunjukkan penurunan nilai HOMA-IR (SMD=-0,36, p=0,001), gula darah puasa (SMD=-3,32, p=0,0001), insulin serum (SMD=-1,47, p=0,002), dan peningkatan nilai QUICKI (SMD=0,01, p=0,006).Kesimpulan: Curcumin dapat memberikan efek terapeutik terhadap parameter gangguan metabolik pasien PCOS dan menjadi salah satu tatalaksana alternatif pasien PCOS di masa depan.Kata kunci: kurkuma; gula darah puasa; sindrom ovarium polikistik.

Successful Repair Management for Urinary Bladder Perforation During Myomectomy on Cervical Myoma on Patients with Previous Cesarean Section: A Challenging Case Report Indra Adi Susianto; Ferry Santoso; Iwan Prasetyo; Diana Novitasari; Dimas Sindhu Wibisono; Jerry Ferdinand Haposan Saragih
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 2 Juli 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v6.n2.497

The 20-25% incidence of uterine myoma often experienced by women in childbearing age and 2% of these uterine myomas attach and grow in the uterine cervical area. The chief complain of cervical myom are lumps in the lower abdomen that are getting bigger and pressing on the urinary bladder cause difficulty in urinating and are accompanied by bloody urine, although the amount of menstrual blood is still within reasonable limits. Like uterine myomas, cervical myomas are not fused with the myometrial lining but are covered by thin connective tissue on the surface.The procedure of cervical myoma based on ACOG (American College of Obstetrics and Gynecology) is hysterectomy if the patient no longer wants to get pregnant, or myomectomy if the patient still wants to have children. Both of these actions have a very high risk in which vascularization in the pelvic area will be very complex, pressure on cervical myoma will have a high risk of injuring the urinary bladder mucosa and when setting aside the lower segment of the uterus there is a risk of injury. We present a 38-year-old woman with 30x 26 x 22 cm giant cervical myoma and secondary infertility that was treated with challenging laparotomi myomectomy in colaboration with urologist to preserve fertility. There was a tear in the upper part of the urinary bladder which was elongated with irregular edges measuring 12 x 5 cm after enucleation cervical myoma. The tear was repaired immediately and there are no complications in the form of vesico-vaginal fistulas or vesico-cervical postoperatively. Penanganan Komplikasi Perforasi Vesika Urinaria saat tindakan Miomektomi pada Mioma Servikal pada Pasien Bekas Seksio Sesaria: Sebuah Laporan KasusAbstrak20-25% insiden neoplasma jinak ini sering dialami oleh wanita terjadi pada wanita usia subur dan 2% nya melekat dan tumbuh pada area servik uteri. Meskipun jumlah darah menstruasi masih dalam batas wajar, tapi keluhan dari mioma uteri yang melekat pada servik adalah benjolan pada perut bawah yang semakin membesar dan menekan pada vesika urinaria sehingga menyebabkan kesulitan berkemih. Menurut American Collage of Obstetric and Gynecology tindakan miomektomi apabila pasien masih ingin mempunyai keturunan. Meskipun resiko yang sangat tinggi karena vaskularisasi area pelvis sangat kompleks, tindakan inijuga beresiko mencederai mukosa vesika urinaria dan resiko cedera pada ureter tunnel. Tulisan ini merupakan kasus seorang wanita berusia 38 tahun dengan mioma serviks permagna berukuran 30 x 26 x 22 cm dengan infertilitas sekunder yang dilakukan miomektomi secara laparotomi bersama ahli urologi. Terdapat perforasi pada vesica urinaria bagian atas memanjang dengan tepi tidak beraturan berukuran 12 x 5 cm setelah tindakan enukleasi mioma serviks. Robekan tersebut dapat diperbaiki dan tidak ada komplikasi berupa fistula vesiko- vagina atau vesiko-serviks pasca operasi.Kata kunci: Perforasi Kandung Kemih, Miomektomi, Mioma Serviks, Infertilitas Sekunder

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Wiryawan Permadi

Contact Email
obgyniajurnal@gmail.com

Phone
-

Journal Mail Official
obgyniajurnal@gmail.com

Editorial Address
-

Location
Kota bandung,

Jawa barat

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Wiryawan Permadi

Contact Email obgyniajurnal@gmail.com

Phone -

Journal Mail Official obgyniajurnal@gmail.com

Editorial Address -

Location Kota bandung, Jawa barat INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Wiryawan Permadi

Contact Email
obgyniajurnal@gmail.com

Phone
-

Journal Mail Official
obgyniajurnal@gmail.com

Editorial Address
-

Location
Kota bandung,

Jawa barat

INDONESIA