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INDONESIA
Indonesian Journal of Medicine
Published by Universitas Sebelas Maret
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
Arjuna Subject : -
Articles 7 Documents
 1 
Search results for , issue "vol.11 no.2 (2026)" : 7 Documents clear
The Diagnostic and Therapeutic Challenges of A Progressive Male Breast Cancer with Brain Metastases: A Case Report Putra, Benaya; Hamdani, Fakhriel Muhammad; Afnan, Alvin
Indonesian Journal of Medicine Vol.11 No.2 (2026)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2016.1.2.927

Abstract

Background: Male breast cancer (MBC) is a rare malignancy that is often associated with advanced stages and poor prognosis due to lack of public awareness and early screening, along with stigmatization of the disease. Aims: This case report aims to highlight the diagnostic and therapeutic challenges of rapidly-progressive MBC in resource-limited healthcare, particularly those compounded by systemic and patient-attributable delays, and emphasize the importance of prevention and early detection of breast cancer in the male population. Subject report: We report the case of a 71-year-old man with a three-month history of a progressively enlarging lump on right breast, weight loss, and right-sided hemiparesis. Medical history included chronic heart failure, dyslipidemia, heavy smoking, and labour work background. The diagnosis of invasive ductal breast carcinoma was established through clinical assessment, imaging, and biopsy. Results: The patient underwent primary tumor resection (PTR) in the form of radical mastectomy, where the main purpose was tumor debulking, revealing tumor invasion into the pectoralis major muscle (pT4 disease). The clinical course was severely impacted by Treatment Delay, encompassing Provider Delay and Patient Delay, which was caused by logistical, operational, and policy barriers. This delay critically postponed the scheduled non-contrast computed tomography (CT) of the head. The delayed CT subsequently revealed multiple metastases. The patient was then referred for immunohistochemistry (IHC) evaluation and systemic therapies but passed away before the scheduled workup due to a declining neurological state from confirmed brain metastases. Conclusion: This case underscores how the challenges of rapidly progressive MBC with brain metastases, combined with a variety of delays and constrained treatment options, resulted in a poor outcome. It highlights the critical need for increased awareness, stigma reduction, and streamlined resource pathways to improve early detection and timely intervention in resource-limited settings.
IMPACT OF PATENT DUCTUS ARTERIOSUS CLOSURE ON LINEAR GROWTH AND WEIGHT GAIN IN CHILDREN: A PROSPECTIVE COHORT STUDY Widjaja, Sri Lilijanti; Putri, Pritania Prameswara; Artiko, Bagus; Anniazi, Masayu Lubna; Ahmadwirawan, Mylco Trisaputra
Indonesian Journal of Medicine Vol.11 No.2 (2026)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2026.11.2.944

Abstract

Background: Patent ductus arteriosus (PDA) can cause pulmonary circulatory volume overload and hemodynamic disturbances that result in feeding difficulties, recurrent infections, and growth retardation. PDA closure intervention is expected to improve physiological conditions, thereby supporting improvements in linear growth and weight gain. Subject and Methods: This prospective cohort study was conducted at Dr. Moewardi General Hospital from January 2024 to July 2025. The target population was children diagnosed with patent ductus arteriosus (PDA). Subject was all of pediatric PDA patients at Dr. Moewardi General Hospital Surakarta who underwent PDA closure procedures (total sampling). Subjects with complete anthropometric data such as body weight and height at PDA pre-procedure, with 3 and 6 months after PDA procedure (post-procedure) were selected. The dependent variables were changes in height (cm) and body weight (kg), measured using standard anthropometric methods. Data were analyzed using the Friedman test for repeated measures, followed by paired Wilcoxon tests with Bonferroni correction for post-hoc comparisons. Results: Total there were 48 children who underwent PDA closure with complete anthropometric data at PDA pre- and 3 to 6 months post-procedure. Mean height significantly increased 4.5% from 83,60 ± 26,23 cm at PDA pre-procedure to 87,34 ± 24,87 cm at 3 months post-procedure, and increased 8.1% to90,39 ± 23,64 cm at 6 months post-procedure( p<0,001). Mean body weight also significantly increased 9.3% from 11,49 ± 12,21 kg at PDA pre-procedure to 12,56 ± 11,93 kg at 3 months post-pocedure then increase 16.1% to 13,34 ± 11,88 kg at 6 months post-procedure (p<0,001). The height and weight of children with PDA closure increased over the observation period. Conclusion: PDA closure is associated with a significant increase in linear growth and weight gain up to 6 months post-procedure.
Correlation of Serum Immunoglobulin-E Level With Allergic Rhinitis Severity Based on Symptoms Classification Widuri, Asti
Indonesian Journal of Medicine Vol.11 No.2 (2026)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2026.11.2.946

Abstract

Background: Allergic rhinitis (AR) is defined as an Imunoglobulin-E (IgE) -mediated reactions to inhaled allergens in atopic individual, with symptoms including runny nose, itchy nose, nasal congestion, and sneezing.  Serum IgE was a reliable diagnostic marker for allergic rhinitis. This study aimed to reveal the correlation between IgE levels and the severity of allergic rhinitis symptoms according to the Allergic Rhinitis and Its Impacts on Asthma (ARIA) classification. Subject and Methods: A cross-sectional observational study was conducted involving 45 patients diagnosed with allergic rhinitis at the Otorhinolaryngology outpatient clinic. Subjects were identified through clinical evaluation, blood screening, and skin prick tests. Serum total IgE levels were measured using the enzyme-linked immunosorbent assay (ELISA) method. Allergic rhinitis severity was categorized according to the ARIA classification into mild and moderate groups. Data were analyzed using the Chi-square test, and the association was presented as prevalence ratio (PR) with a 95% confidence interval (CI). Results: Forty-five patients with allergic rhinitis comprised of 30 females (66.70%) and 15 males (33.30%). The average IgE levels examination results were 204.24 IU/ml, with 23 subjects (48.89%) classified as standard, while those with higher-than-normal IgE levels were 22 subjects (53.49%). The Pearson chi-square test showed a significant correlation between higher-than-normal IgE levels and ARIA severity (PR = 1.65; 95% CI = 1.03–2.64; p = 0.045) Conclusion: Elevated serum IgE levels were significantly associated with greater allergic rhinitis severity based on ARIA classification and may serve as a useful supporting marker for disease severity assessment.
Unilateral Left-Sided Tessier Type 4 Facial Cleft in a 6-Mont-Old Infant: A Case Report with Surgical Reconstruction and Outcome Fadli Robby Amsriza; Rizka Fakhriani
Indonesian Journal of Medicine Vol.11 No.2 (2026)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2026.11.2.952

Abstract

Background: Cleft Tessier is the most complex classification characterized by oro-orbital malformations with a transverse defect in the mouth extending to the nose and crossing to the lower eyelids. Recent research shows a lack of optimal reconstruction techniques, both surgical methodology and procedural. This case report aims to describe the clinical presentation, surgical reconstruction methodology, and outcomes in a 6-month-old baby with a left unilateral Tessier type 4 facial cleft. Subject and Methods: A 6-month-old female newborn appears with a congenital left unilateral facial cleft that has existed since birth.  Ocular examination showed partial involvement of the lower eyelid with a risk of exposure, while the eyeball was intact. Tessier type 4 cleft arises from failure of fusion between the maxillary and lateral nasal prominences during embryogenesis. Results: Surgical management focuses on restoring both function particularly ocular protection and oral competence and facial aesthetics. Early intervention during infancy offers advantages such as improved tissue healing, better adaptation to facial growth, and reduced psychosocial impact. The reconstruction results achieved good initial functional and esthetic outcomes. Further monitoring during the growth period is necessary to assess facial asymmetry and hyperpigmentation that may occur. Conclusion: Infant reconstruction can yield better esthetics and function, although monitoring and follow-up actions are necessary.  
When the Eustachian Tube Is Normal: Selective Epitympanic Dysventilation Syndrome in Primary Acquired Cholesteatoma – An Evidence-Based Case Report Pratiwi, Dewi; Sudrajad, Hadi; Primadewi, Novi; Ramliana, Dienia Nop
Indonesian Journal of Medicine Vol.11 No.2 (2026)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2026.11.2.953

Abstract

Background: Primary acquired cholesteatoma is a benign yet locally destructive middle ear lesion with an incompletely understood pathogenesis. While Eustachian tube dysfunction is commonly implicated, it does not explain cases with normal middle ear pressure. Selective epitympanic dysventilation syndrome (SEDS) has been proposed as an alternative mechanism involving localized ventilation impairment within the epitympanum. This study aims to provide a clearer understanding of the clinical features of cholesteatoma associated with SEDS, which may help clarify its etiopathogenesis, support earlier detection, limit disease progression, and guide more appropriate, individualized clinical decision-making. Case presentation A 55-year-old female presented with one year of persistent, malodorous left otorrhea and progressive hearing loss over three months. Otoscopy revealed mucopurulent discharge with an attic perforation. Nasoendoscopy showed a patent Eustachian tube. Audiometry demonstrated mild conductive hearing loss (31.25 dB), and tympanometry showed a Type A curve, indicating normal middle ear pressure. Mastoid MSCT revealed opacification of mastoid air cells and antrum with intact ossicles and no mesotympanic involvement, suggesting a localized ventilation disorder consistent with SEDS. Conclusion: SEDS is an important and underrecognized mechanism in primary acquired cholesteatoma. Its recognition is essential for early diagnosis and for guiding surgical strategies that restore epitympanic ventilation to prevent recurrence.
Identification of Physiotherapy Problems in Patients with Chronic Obstructive Pulmonary Disease at Respira Hospital Yogyakarta: An Observational Study Kusumaningtyas, Mei; Handari, Herdianty Kusuma; Prayitno, Prayitno
Indonesian Journal of Medicine Vol.11 No.2 (2026)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed....955

Abstract

Background: Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality worldwide. Common symptoms include dyspnea, chest pain, reduced thoracic expansion, and impaired pulmonary function. This study aimed to identify physiotherapy-related problems among patients with COPD at Respira Hospital Yogyakarta. Subject and Methods: This observational study was conducted from June to August 2025 at the Physiotherapy Outpatient Clinic of Respira Pulmonary Hospital, Yogyakarta. Physiotherapy-related problems were assessed using the modified Medical Research Council (mMRC) Dyspnea Scale, COPD Assessment Test (CAT), thoracic mobility measurements, Visual Analog Scale (VAS), Peak Flow Meter (PFM), and Incentive Spirometer. Results: A total of 102 patients with COPD participated in the study. Most participants were male (60.8%). Grade 2 dyspnea was reported by 50.0% of subjects, while 65.7% had moderate COPD symptoms. Impaired thoracic mobility was observed in 40.2%–47.1% of patients. Chest pain was reported by only one subject. Severe airflow obstruction was found in 60.8% of participants, with a mean peak expiratory flow of 52.08% of the predicted value. Impaired inspiratory capacity was identified in 48.0% of subjects. Conclusion: The main physiotherapy-related problems identified among patients with COPD at Respira Hospital Yogyakarta were dyspnea, COPD symptoms, impaired thoracic mobility, reduced peak expiratory flow, and decreased inspiratory capacity.
Association Between Early-Life Nutritional Practices and Children's Feeding and Swallowing Skills Putri, Anggi Resina; Mangunsong, Roy Romey Daulas
Indonesian Journal of Medicine Vol.11 No.2 (2026)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2026.11.2.960

Abstract

Background: Children's feeding and swallowing abilities are vital functions that support optimal growth and development, involving the complex coordination of muscles and neural systems to ensure the safe and efficient consumption of food. This study aimed to analyze the role of early-life nutritional practices in the development of feeding and swallowing abilities among children in the Surakarta region using logistic regression analysis. Subjects and Method: This cross-sectional study was conducted in Surakarta, Central Java, from April to August 2025 and involved 50 children selected through purposive sampling. The indepen­dent variables were lactation-based early nutrition and post-lactation complementary nutrition practices, while feeding and swallowing abilities served as the dependent variables. Data were collected through interviews, observations, questionnaires, and the Dysphagia Disorder Survey (DDS). Associations between variables were analyzed using logistic regression in Stata 13. Results: The results of this study indicated that both a history of appropriate lactation-based early nutrition and appropriate post-lactation complementary nutrition practices were significantly associated with children's feeding and swallowing abilities. Children with a history of lactation-based early nutrition (b= 3.13; 95% CI= 0.97 to 4.27; p= 0.002) and appropriate post-lactation complemen­tary nutrition practices (b = 2.48; 95% CI = 0.49 to 4.23; p = 0.013) were more likely to demonstrate appropriate feeding abilities. Similarly, children with a history of lactation-based early nutrition (b = 3.11; 95% CI= 1.08 to 4.76; p= 0.002) and appropriate post-lactation complementary nutrition practices (b= 3.03; 95% CI= 1.10 to 5.18; p= 0.002) were more likely to exhibit appropriate swallowing abilities. Conclusion: This study concludes that both lactation-based early nutrition and appropriate post-lactation complementary nutrition practices are significant determinants of feeding and swallowing abilities in children.

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