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INDONESIA
Indonesian Journal of Medicine
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
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Articles 407 Documents
Effect of Exercise on Cognitive Ability, Cardiovascular Fitness, and Quality of Life in Post-Stroke Patients: Systematic Review and Meta-Analysis Maingu, Bertha Sylvester; Murti, Bhisma; Widyaningsih, Vitri
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.737

Abstract

Background: Following a stroke, cognitive ability, and cardiovascular fitness decline, exerting a substantial influence on physical rehabilitation and overall quality of life. Stroke management encompasses a multidisciplinary approach, with emerging studies highlighting the role of exercise in enhancing cognitive ability and cardiovascular fitness post-stroke. This study aims to analyze the effects of exercise on cognitive ability, cardiovascular fitness, and quality of life in stroke survivors, shedding light on potential therapeutic benefits. Subject and Methods: The PICO Model eligibility criteria were employed to execute the article search including P= post-stroke patients; I= exercises C= standard care, O= cognitive ability OR cardiovascular fitness OR quality of life. The study extracted articles from PubMed and Science­Direct databases, with keywords "exercises" AND "cognitive ability" OR "cardiovascular fitness" OR "quality of life" AND "post-stroke patients". Inclusion criteria required full-text articles with rando­mized controlled trial (RCT) designs, focusing on post-stroke patients and evaluating improve­ments in cognitive ability, cardiovascular fitness, or quality of life. PRISMA diagram and Review Manager 5.4.1 tool were used to analyse the selected articles. Results: 25 studies included in the review had 2,110 participants, across Asia; Australia, Europe, North America, and South America eligible for meta-analysis. The result indicated a positive effect of exercise on cognitive ability (SMD=0.68, CI 95% (0.21 to 1.16); p=0.005); cardiovascular fitness (SMD=0.63, CI 95% (0.17 to 1.08); p=0.007) and quality of life (SMD=0.60, CI 95% (-0.08 to 1.27); p=0.080). Conclusion: Engagement in diverse forms and durations of exercise emerges as a crucial element in post-stroke rehabilitation. This intervention signifies a promising avenue toward enhancing cognitive abilities, and cardiovascular fitness, and potentially elevating quality of life among stroke survivors.
The Role of Hypertonic Saline in Managing Malignant Cerebral Edema Due to Large Vessel Occlusion Stroke: A Case Report Zairinal, Ramdinal Aviesena; Malutfi, Chandrika Najwa; Hidayati, Diah Balqis Ikfi
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.738

Abstract

Background: Malignant cerebral edema (MCE) is a complication of large vessel occlusion stroke mainly treated by decompressive craniectomy. The aim of this case report is to demonstrate the efficacy of providing hypertonic saline (3% NaCl) as an alternative treatment for reducing intracranial pressure (ICP) in an MCE patient who refuses surgery. Case Presentation: A 66-year-old man went to the emergency department with unconsciousness, right-sided hemiplegia, and global aphasia for 4.5 hours before admission. His National Institutes of Health Stroke Scale (NIHSS) score was 12. The patient’s brain magnetic resonance imaging (MRI) revealed a large infarction on the left frontotemporoparietal lobe which caused a subfalcine herniation 1.4cm to the right side. He also suffered hyponatremia (115mmol/L). The family refused decompressive craniectomy. The patient received 200ml of 3% NaCl drip intravenous as an initial dose over 20 minutes every 6 hours. Subsequent administration is gradually reduced every 25ml with a distance adjusted to the patient’s condition up to 50ml as the last dose. The patient’s 90-day modified Rankin Scale (mRS) score was 4. Results: The patient with MCE in this case who was administered 3% NaCl as conservative therapy had satisfactory outcomes, as demonstrated by the improvement of the clinical neurological condition. Conclusion: In patients who decline surgery, 3% NaCl might be given as a conservative treatment option to reduce ICP while maintaining serum sodium levels under control. This case revealed a positive clinical result without complications.
Effect of Nerve Mobilization in Reducing Pain in Patients with Guyon Canal Syndrome Maliesgasari, Dita; Sudaryanto, Wahyu Tri
Indonesian Journal of Medicine Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.1.742

Abstract

Background: Guyon Canal Syndrome is a peripheral ulnar neuropathy caused by lesions of the distal ulnar nerve, specifically in the Guyon's tunnel which is at the base of the hypothenar eminence where the ulnar nerve branches and is susceptible to compression. These tunnel structures are frequently subject to cycling-related injuries, sudden compression or repetitive vibration. Guyon Canal Syndrome causes loss of motor, sensory function, or a combination of motor and sensory function. The aim of this research is to determine the effect of nerve mobilization on reducing pain in Guyon Canal Syndrome. Subjects and Method: This research is a quasi-experimental research conducted at the Grhasia Mental Hospital, Yogyakarta Special Region, in June-July 2023. A total sample of 8 patients diagnosed with Guyon canal syndrome was selected using purposive sampling. The sample was divided into 2 groups (1) 4 people received nerve mobilization and (2) 4 people received standard care. The dependent variable is pain. The independent variable is nerve mobilization. Pain was measured using the Quadruple Visual Analogue Scale (QVAS). The difference in pain scores before and after intervention in the two groups was tested using an independent t test. Results: The average difference in pain score reduction in the intervention group (Mean= -11.75; SD= 5.68) was greater than the control (Mean= -3.5; SD= 11.39), but not statistically significant (p= 0.242). Conclusion: The average difference in pain score reduction in the intervention group was greater than the control, but not statistically significant. Keywords: Guyon canal syndrome, pain, nerve mobilization
Nurse’s Characteristics and Their Understanding Regarding the Compatibility of Mixing Intravenous Drug Preparations in Hospital Settings Rizky Wiharti, Irda; Karuniawati, Hidayah
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.744

Abstract

Background: Drug incompatibility can occur in patients in hospital who receive one or more drugs at the same time due to incompatible drug mixing, and the mixture is said to be incompatible if there are precipitates, crystals, visual color changes. This research aims to determine the relationship between nurses' knowledge of incompatibility in mixing intravenous drug preparations, so that collaboration between nurses and pharmacists can occur in administering intravenous drugs and can reduce the occurrence of medication errors, especially when administering intravenous drugs. Subjects and Method: Cross sectional research was conducted in RSUD dr. Soeselo, Tegal, Central Java, November 2023. The research subjects were 152 nurses selected using purposive sampling technique. The dependent variable is knowledge. The independent variables are age, gender, length of work, duration of work, and training. Data was collected using a questionnaire and analyzed using multiple linear regression. Results: The number of survey respondents in this study was 152 people, with the majority being 73.7% female and 26.3% male. The average value of the nurses' age was 31.82 ± SD 5.09 and 6.14 ± SD 3.26 for the length of work of the nurses who took part in this study, and the average duration of work was 10.08 ± 2.00. In the multivariate analysis test, gender, last education, duration of work, length of work, age on knowledge had a p value of >0.005 so there was no significant effect. Conclusion: The majority of nurses still have a poor level of knowledge <75% on several questionnaire items. Apart from that, this research shows that there are still many nurses who do not understand intravenous stability and the stages of intravenous administration, which is shown in the question scores. So the role of clinical pharmacy in monitoring and providing education regarding nurse training regarding drug incompatibility is needed.  
The Effect of a Combination of Ultrasound and Stretching on the Pain Scores of Piriformis Syndrome Patients at the Padas Health Center, Ngawi Regency Imani, Kelvin Teguh; Fariz, Achmad; Hamidah, Nurul
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.746

Abstract

Background: Piriformis Syndrome is a pain in the pelvic area caused by prolonged or excessive contraction of the piriformis muscle so that the sciatic nerve is compressed or compressed. The physiotherapy treatment used is a combination of ultrasound and stretching. This study aimed to determine the effect of a combination of ultrasound and stretching in reducing pain in piriformis syndrome patients. Subjects and Method: The design of this study was a one-group pre-experimental and post-test design with 20 respondents who met the inclusion and exclusion criteria using a purposive sampling technique carried out in September-October 2023. Respondents had their pain scale measured using VAS (Visual Analog Scale) before and after physiotherapy treatment, namely; giving a combination of ultrasound and stretching 2 times a week for 4 weeks. Results: This study used the paired sample test hypothesis test with the median VAS value; (1) pre by 5.70; (2) posts by 3.35 and (3) P value by 0.00. Conclusion: It can be concluded that the combination of ultrasound and stretching is effective in reducing pain in cases of piriformis syndrome.
Surgical Precision in Lumbar Spinal Canal Stenosis: Optimizing Outcomes in a Young Adult with Suspected Infection through Decompression-Stabilization-Fusion Putra, I Gusti Ngurah Paramartha Wijaya; Febyan; Ustriyana, Nyoman Gede Grenata Nanda
Indonesian Journal of Medicine Vol. 9 No. 2 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.2.747

Abstract

Background: This case report examines the uncommon occurrence of Lumbar Spinal Canal Stenosis (LSCS) in a 23-year-old male patient, highlighting the diagnostic challenges and unique aspects of managing this condition in young adults. Typically associated with aging and degenerative changes, LSCS poses a diagnostic dilemma when encountered in a young individual with nonspecific causation. Case Presentation: The patient reported persistent lower back pain since February 2023, primarily on the right side, escalating over the past three months. The pain intensified during prolonged sitting, standing, and walking, alleviated by lying down and analgesics. Radiating pain to both buttocks and legs, particularly on the right side, accompanied a four-month history of persistent right foot numbness. Referred from RS Siloam Kupang to RSAD Denpasar and subsequently to RSUP Prof IGNG Ngoerah, the patient received a diagnosis of Lumbar Spinal Canal Stenosis at L2-L3-L4, L5-S1, with suspected Spondylitis TB. Results: This case underscores the intricacies of diagnosing Lumbar Spinal Canal Stenosis in young adults, emphasizing the exploration of non-traditional causes. The patient underwent Debridement-Decompression-Stabilization-Fusion-Biopsy+Culture, experiencing postoperative improvement. Cultures showed no growth, and biopsy results were nonspecific. The final diagnosis was Lumbar Spinal Canal Stenosis at L2-L3-L4, L5-S1 due to Spondylitis TB dd/Pyogenic Infection, with bilateral Neural Foraminal Stenosis Grade III at L5. The discussion focuses on the rarity of this presentation in young individuals, challenges in diagnosis, and the efficacy of decompression-stabilization-fusion treatment for achieving positive outcomes in young adult patients. Conclusion: The case discussion emphasizes the complexity of managing Lumbar Spinal Canal Stenosis in a young adult, particularly when infection is suspected. The decision to pursue Decompression-Stabilization-Fusion was rooted in the patient's age, the need for structural stability, and the suspicion of infection.
Unveiling Atopic Dermatitis: Exploring Smoking, Obesity, and Fast Food as Pivotal Risk Factors - A Systematic Review Hibatullah, Faiz Nur; Kalada, Elisabeth Chelsea Uma; Baita, Etina Noor; Putra, Fabianus Yvan Marino Cahaya; Adiwinoto, Ronald Pratama; Prasetya, Hanung
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.750

Abstract

Background: Atopic dermatitis (AD), also known as Eczema, is an inflammatory skin disease that causes dry, itchy skin. several risk factors for AD have been reported including demographics, socioeconomics, active and passive smoking, urbanization, diet, breastfeeding and timing of introduction of solid foods, obesity, physical exercise, fast food, and environmental air pollution. This study aims to better understand the effect of smoking, obesity, and fast food consumption as one of the risk factors of AD. Subjects and Method: Systematic review with the help of PICOs to search for eligible articles. Articles were searched from 3 different databases (PubMed, ScienceDirect, and Google Scholar) with the help of a search engine application, Publish or Perish (PoP), using the following keyword: “smoking AND atopic dermatitis”, “fast food AND atopic dermatitis”, “obesity AND atopic dermatitis”. Results: 10 articles matched the specified inclusion and exclusion criteria for this study. Whether or not smoking causes AD is still conflicting, few studies reported there is no correlation between smoking and AD, whereas other studies said otherwise. In contrast to that, second-hand smoke was found to be affecting AD conditions more (up to 2.320). Most of our eligible articles reported that obesity did cause severe reactions of AD up to 1.62 times. Frequent fast food consumption was also found to be causing severe AD conditions (OR=1.580). Conclusion: Obesity and fast food consumption are one of the causes of AD development and AD severity. The risk factor of cigarette smoking still conflicts with whether or not it affects AD conditions.
Application of the Health Belief Model for Assessing Risk Behavior among Patients Experiencing Musculoskeletal Pain Treated with Acupuncture in Surakarta Aditya, Stefanus; Murti, Bhisma; Demartoto, Argyo
Indonesian Journal of Medicine Vol. 9 No. 2 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.2.752

Abstract

Background: Musculoskeletal pain is a complaint that occurs in parts of the skeletal muscles which is felt by a person ranging from mild complaints to very painful. This study aimed to analyze the effects of perceived vulnerability, perceived benefits, perceived barriers, and self-efficacy on risky behavior in patients complaining of musculoskeletal pain treated with acupuncture. Subjects and Method: This was a cross-sectional study conducted in Surakarta, from November-December 2023. A total of 200 patients were selected using fixed disease sampling. The dependent variable was risk behavior for musculoskeletal pain. The independent variables were perceived vulnerability, perceived vulnerability, perceived benefits, perceived barriers, cues to action, and self-efficacy. The data were analyzed using a multiple linear regression. Results: Musculoskeletal pain risk behaviors (MSDs) decreased with increasing perceived susceptibility (b= -0.22; 95% CI= -0.29 to -0.16; p<0.001), perceived benefit (b= -0.09; 95% CI= -0.13 to -0.05; p<0.001), and self-efficacy (b= -0.06; 95% CI= -0.11 to -0.01; p=0.015) and increased with increasing perceived barriers (b= 0.05; 95% CI= 0.02 to 0.09; p= 0.002). Conclusion: Perceived vulnerability, perceived benefits, and self-efficacy decrease risk behavior in musculoskeletal pain patients, and perceived barriers increase risk behavior in musculoskeletal patients.
Effectiveness of Ethanol Extract and Ethyl Acetate Fraction of Breadfruit Leaves (Artocarpus altilis) as Antihyperglycemia Daulay, Agus Husein; Siahaan , Jekson Martiar; Syahrir, Lesmana; Tambunan, Ronald Tunggul Hotmarojahan
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.753

Abstract

Background: The rising diabetes mellitus (DM) population is a public health concern. Pharmaco­therapy for DM can cause side effects and is often inaccessible, necessitating alternative therapies like medicinal plants. Breadfruit leaves (Artocarpus altilis) have antidiabetic effects. This study aimed to examine the antihyperglycemic effect of ethanol extract and ethyl acetate fraction of bread­fruit leaves on alloxan-induced diabetic male white rats (Rattus norvegicus). Subjects and Method: This was a randomized controlled trial. Sample was 35 male white Wistar rats (Rattus norvegicus sp.) divided into 7 groups. The study was conducted at the Phytochemical Laboratory and Animal House, Faculty of Medicine, Indonesian Methodist University, from April to May 2023. The dependent variables were body weight, blood glucose levels, and diameter of the islets of Langerhans. The independent variables were variations in the dose of ethanol extract and ethyl acetate fraction of breadfruit leaves. Body weight was measured by scales. Blood glucose was measured using glucometer. Diameter of the islets of Langerhans was measured using computer-based image analysis system. Data were analyzed using Anova and Kruskal-Wallis tests. Results: Weight loss was better in the group given the ethyl acetate fraction at a dose of 200 mg/kgBW compared to the other groups. Administration of ethanol extract at a dose of 200 mg/kgBW showed a better reduction in blood glucose levels compared to the other groups, where P < 0.05 between K4 and K3, K5, and K7 on day 5. Ethanol extract at a dose of 200 mg/kgBW was able to improve the diameter of the islets of Langerhans induced by alloxan. Conclusion: A 200 mg/kg BW dose of ethyl acetate fraction reduces body weight. A 200 mg/kg BW dose of ethanol extract reduces blood glucose and improves pancreatic islet diameter.
Citicoline in Acute Ischemic Stroke: Case Report Rimbun, Surjadi; Anto, Endy Juli
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.764

Abstract

Background: Stroke is the third most common disease after heart disease and cancer and a leading cause of disability worldwide. The most common type of stroke is non-hemorrhagic stroke (SNH) or Acute Ischemic Stroke, which accounts for about 85-87% of all cases. The purpose of this case report is to examine the benefits of citicoline in a patient with SNH. Case Presentation: In this case, a 63-year-old man was admitted to the Emergency Room of the Agung Mulia Inpatient Clinic on February 25, 2023 with complaints of inability to move his right arm and leg since 5 days before entering the clinic. The complaint was felt suddenly when the patient woke up in the morning. The patient also complained of weakness and difficulty speaking and slurred speech accompanied by difficulty swallowing. The voice could still speak but was unclear but the patient understood what was being said to him. Other complaints such as headaches, nausea, vomiting, bowel and urination disorders, and fainting were denied by the patient. The patient was treated at a hospital near his house on February 21, 2023 and underwent a CT scan of the head and was treated as an outpatient. The results of the CT scan on February 21, 2023, axial section of the head without intravenous contrast, obtained the following results: Infraterritorial cerebellum and 4th ventricle appear normal, Supreterritorial hypodense lesions appear on the left lateral periventricular and in the left parietal, No midline shift, Cortical sulci and prominent ventricular system. It was concluded that the left lateral periventricular and left parietal cerebral infarction were in accordance with Non-Hemorrhagic Stroke (SNH). Senile cerebral atrophy. Based on anamnesis, physical examination, and supporting examinations. The clinical diagnosis in this case was right hemiparesis and paresis of nerves VII, IX, and X, et causa non-hemorrhagic stroke (SNH) with electrolyte disorders (Electrolyte Imbalance), given general and specific management. Results: For general management that can be given is semi-fowler position, oxygen administra­tion, administration of antihypertensive drugs and maintaining fluid and nutritional intake. While specific management with pharmacology by administering citicoline and clopidogrel is given to this patient. Conclusion: Citicoline works to prevent brain damage (neuroprotection) and helps the formation of cell membranes in the brain (neurorepair). The benefits of citicoline in this patient are seen in motor and neurological improvements based on NIHSS assessments.