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INDONESIA
Indonesian Journal of Medicine
Published by Universitas Sebelas Maret
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
Arjuna Subject : -
Articles 407 Documents
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The Effect of Using a Dynamic Wrist Splint on Wrist Pain in Stroke Patients Rachmat, Nur; Kuncoro, Bambang; Prasetya, Hanung
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.796

Abstract

Background: Hand movement function in hemiplegic stroke patients is impaired due to contractures and spasticity. Pain in the wrist joint often occurs when moved. This research aims to determine how dynamic wrist splints can reduce wrist pain in stroke patients. Subjects and Method: This was a quasi-expe­rimental study. The subjects were 20 hemiplegic stroke patients in Colomadu Karanganyar. The research was carried out in July – September 2023. The dependent variable was wrist pain. The independent variable was the use of a dynamic wrist splint. measurement the degree of pain using the Visual Analog Scale which is used to determine the level of pain felt by the sufferer. Data normality test using Shapiro-Wilk. The statistical test used in this research is wilxocon. Results: The ages of subjects ranged from 30 to 62 years. Wrist pain was reduced after the use of a dynamic wrist splint compared to levels before its use. Conclusion: There is an influence of dynamic wrist splints on wrist pain in stroke patients.
Clinical Outcomes Comparison in Administration of Secretome vs Hyaluronic Acid in Patients with Knee Osteoarthritis Kellgren-Lawrence Grade I-III Aryana, I Gusti Ngurah Wien; Suyasa, I Ketut; Dharmayuda, Cokorda Gde Oka; Febyan; Gunawan, Dary
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.798

Abstract

Background: The prevalence of OA in Indonesia is predicted to reach more than 20% of the population aged over 60 years in 2050, with a high risk of disability. So far, early treatment of osteoarthritis in the form of administering hyaluronic acid has not been completely satisfactory and tends to be progressive until ending in more invasive operative therapy. This study aimed to compare the clinical outcomes between secretome injection and hyaluronic acid in patients with Kellgren-Lawrence grade I-III knee osteoarthritis. Subjects and Method: This was a single-blind experimental study. This study was conducted in the orthopedic polyclinic at General Hospital Prof. Dr. I.G.N.G. Ngoerah Bali. A total sample of 36 knee osteoarthritis patients was selected using permuted block sampling with randomization. The sample was divided into two groups, (1) secretome (intervention group) and (2) hyaluronic acid (control group). The independent variables were secretome injection and hyaluronic acid injection. The dependent variable was pain. Pain was measured using Western Ontario and McMaster University (WOMAC), Knee Osteoarthritis Outcome Score (KOOS), Visual Analog Score (VAS), and Patient-Reported Outcome Measure (PROM). Results: Based on gender, there are more women than men and the right foot is more affected at 58.3%. Functional score parameters in each secretome and hyluronic acid group were compared between the 3rd and 6th months of follow-up. Pain in the hyaluronic acid group was lower than in the secretome group. Conclusion: Hyaluronic acid has better effect in pain reduction than secretome. Further studies could explore the underlying mechanisms and potential long-term effects to better understand these differences in pain outcomes.
Effect of Moringa Leaf Infusion (Moringa oleifera) on Reducing Blood Glucose and Total Cholesterol Levels in Mice (Mus musculus) with Diabetic Ulcers Napitupulu, Helen Debora; Siahaan, Jekson Martiar; Simangunsong, Batara
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.799

Abstract

Background: Diabetes mellitus is a chronic disease in the form of metabolic disorders, which is characterized by blood glucose levels (KGD) that exceed normal limits and are accompanied by impaired metabolism of carbohydrates, lipids, and proteins, as a result of abnormalities in insulin secretion. Diabetics are known to have slow wound healing. Moringa oleifera leaves or moringa plants contain flavonoid compounds, which can decrease glucose absorption. This study aims to determine the effect of moringa leaf infusion on blood sugar levels, glucose tolerance, cholesterol levels, body weight, and wound healing speed in mouse model animals. Subject and Method: This study is experimental using a posttest only controlled group design, using 25 male mice (Mus musculus) divided into 5 groups. The study was conducted at the Phytochemistry and Animal House Laboratory, Faculty of Medicine, Methodist University Indonesia from March to May 2022. The bound variables were body weight measured using a scale, current blood glucose levels and blood glucose levels with glucose loading measured with strips and glucometers, total cholesterol levels measured using strips and cholesterol measuring devices, and the length of mice wounds measured using a ruler. The free variable is the variation in the dose of moringa leaf infusion. The data were analyzed using the Anova and Kruskal-Wallis tests. Results: The administration of moringa leaf infusion had a significant effect on the reduction of the levels of each variable, namely a dose of 10% in body weight, a dose of 30% in KGD, 20% in KGD with glucose loading, 20% in cholesterol, and 20% in wound closure, which was proven based on the results of statistical tests. Conclusion: Moringa leaf infusion can lower blood sugar levels, blood sugar levels by glucose depletion, cholesterol levels, body weight, and accelerate wound healing in sucrose-induced mice, high fat diet, and PTU.
Decline in Estrogen Levels and Its Impact on Muscle Strength in Elderly Women: A Systematic Review Cahyaningrum, Hapsari; Silanurrahmi, Athaya Zuhra; Hakim , Gamadhan Kholid Rahman
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.755

Abstract

Background: In the musculoskeletal system, old age is closely related to a decline in muscle strength. Decreased muscle strength in women is caused by the influence of changes in estrogen hormone levels. Several studies were conducted to see how estrogen affects muscle mass, muscle function, muscle damage, muscle regeneration, inflammation in the body, mitochondrial funct¬ion, and substrate metabolism. Therefore, the study was carried out with the aim of conducting further study focusing on estrogen on muscle strength in elderly women.Subjects and Method: The study was conducted with a systematic review design. The study was carried out in accordance using PRISM guidelines with the PICO formula. Population: elderly women, Intervention: estrogen hormone, Outcome: muscle weakness. Article searches were carried out through several databases, namely PubMed, Cochrane Library, Scopus Database, and Physio-therapy Evidence Database (PEDro) with the keywords: estrogen OR "estrogen hormone" OR "muscle strength" OR "risk of falls" OR "menopause" OR "women elderly." Risk of bias assessment was carried out according to the study design of each article.Results: There were 10 articles involved in this study. The article has a cross-sectional and longitudinal study design. Articles had a low and medium risk of bias assessment. 6 articles stated that there was a relationship between changes in estrogen hormone levels and muscle weakness. 4 articles stated that there was no relationship between changes in estrogen hormone levels and muscle weakness. Conclusion: There is a inconsistent relationship between estrogen levels and muscle strength in elderly women.
Comparison of the Effects of Zig-Zag Run and Shuttle Run Exercises on Agility in Futsal Players Fahri, Ana Mustafiyah; Oktaviani, Vernanda; Asyhari, Atge Oktoreza
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.828

Abstract

Background: Futsal players really need agility so that they can improve their performance and get maximum results as well as improve the body's physiological systems and functions. Physiotherapy plays a role in efforts to improve player achievement by optimizing physical capacity and functional abilities so that maximum achievement is achieved. Agility exercises that can be used to improve agility are obstacle runs, zig-zag runs, and shuttle runs. The purpose of this study is to find out which has a greater effect between the addition of zig-zag run and shuttle run exercises on the agility of futsal players.Subjects and method: This was an experimental study to compare the effect of zig-zag run and shuttle run on agility. 30 futsal players aged 18-23 years were divided into two groups, i.e. zig-zag run and shuttle run, randomly. The dependent variable was agility. The independent variables were zig-zag run and shuttle run. Difference of agility score before and after intervention between groups was tested using independent t-test.Results: There was no difference of agility level between zig-zag run (Mean= 10.06; SD= 0.49) and shuttle run (Mean= 10.02; SD= 0.74) groups before intervention, p= 0.315. After intervention, there was a slight difference of agility level between zig-zag run (Mean= 9.77; SD= 0.43) and shuttle run (Mean= 9.73; SD= 0.74) groups, and it was marginally significant (p= 0.052). Conclusion: After intervention, there is a slight difference of agility level between zig-zag run and shuttle run groups, and it is marginally significant.
Multilevel Analysis of Prognostic Factors for Cognitive Function in Post-Stroke Patients Utami, Sukandriani; Rahardjo, Setyo Sri; Murti, Bhisma; Novika, Revi Gama Hatta; Tamtomo, Didik Gunawan
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.829

Abstract

Background: Stroke is the leading cause of disability and the second leading cause of death worldwide. Post-stroke disability can be in the form of motor, sensory, autonomic, or cognitive impairments. Impaired cognitive function is the leading cause of death and pain in post-stroke patients in the world. Decreased cognitive function is present in more than 70% of post-stroke patients and is associated with disability, independence, and pain. This study aims to analyze the prognosis factors of cognitive function in post-stroke patients.Subjects and Method: This study used a cross-sectional design conducted in 7 hospitals on the island of Lombok from July to August 2024. A total of 200 post-stroke patients were selected using stratified random sampling. The dependent variable in this study was cognitive function examined using the Mini Mental State Examinatio (MMSE) questionnaire. Other independent variables such as age, gender, marital status, pension fund, complications, comorbidities and stroke type were collected using a questionnaire. The data were analyzed using a multilevel double-linear regression model.Results: The prognosis factor of cognitive function in post-stroke patients was age (b=-0.19; CI 95%=-0.29 to -0.10; p=<0.001), marital status (b=-3.80; CI 95%=-6.72 to -0.88; p=0.011), pension fund (b=-5.88; CI 95%= -8.35 to -3.42; p=<0.001), complications (b=-5.37; CI 95%= -7.34 to -3.39; p=<0.001). While sex, comorbidities, and stroke type did not show a significant relationship with the cognitive function of post-stroke patients. Conversely, there was an influence of doctors treating post-stroke patients on cognitive function (ICC=8.76%).Conclusion: Age, marital status, pension funds, and complications are prognostic factors in cognitive function of post-stroke patients. Conversely, there is an influence of doctors who treat post-stroke patients on cognitive function.
Factors Influencing Cervical Cancer Screening Participation in Female: Systematic Review Hastuti, Sri; Wulan, Suryati Kumoro; Widyawati, Melyana Nurul
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.801

Abstract

Background: Cervical cancer is the second leading cause of morbidity and mortality in the world. This can be influenced by several things such as lack of willingness to participate in cervical cancer screening. This review aims to explore factors that influence participation in cervical cancer screening. Subjects and Method: This study is a systematic review with PICO covering: (1) Population: women; (2) Intervention: factors influencing participation; (3) none; (4) level of participation in cervical cancer screening. The databases used are PubMed and JSTOR. Inclusion criteria include full text in Indonesian and English with research subjects in women with cervical cancer. Exclusion criteria in this study were articles published less than five years ago. Results: A total of 21 articles stated that several factors such as interpersonal, intrapersonal, community, organizational, and public policy can influence participation in cervical cancer screening. Conclusion: Intervention strategies based on the reviewed factors need to be improved to reduce cervical cancer morbidity and mortality rates.
Comparison of HbA1c Levels in Normal-Weight and Obese Type 2 Diabetes Mellitus Patients at Dr. Pirngadi General Hospital, Medan, North Sumatra, Indonesia Sagala, Daniela; Nainggolan, Ranatha NH; Sinurat, Suryati; Butar-Butar, Harry; Siahaan , Jekson Martiar
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.802

Abstract

Background: Diabetes mellitus is a collection of metabolic diseases caused by impaired insulin secretion, insulin action, or both so that it has the characteristics of hyperglycemia. Increased will cause a decrease in glucose delivery to the plasma membrane, resulting in insulin resistance in muscle and adipose tissue. This study aimed to compare HbA1c in normal weight and obese individuals with type 2 DM at Dr. Pirngadi hospital.Subjects and Method: This was a cross-sectional study was conducted at Dr. Pirngadi Hospital, Medan, North Sumatera, Indonesia, on May 2022. A sample of 50 patients diagnosed with Type 2 Diabetes Mellitus (T2DM, HbA1c ≥6.5%). The study variables were HbA1c and body mass index (BMI). Independent t-test was used to compare HbA1c levels between normal weight and obese participants.Results: HbA1c in type 2 DM patients with obesity (Mean= 11.49; SD= 0.60) is higher than those with normal weight (Mean= 8.71; SD= 0.34), with p= 0.002.Conclusion: HbA1c in type 2 DM patients with obesity is higher than those with normal weight.
Comparison of The Effectiveness of Remifentanyl versus Fentanyl in Pediatric Undergoing Methotrexate Therapy Purwoko, Purwoko; Putro, Bambang Novianto; Pamungkas, Ferdy; Siswanto, Febby Gunawan
Indonesian Journal of Medicine Vol. 7 No. 1 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Anesthesia procedure is routinely performed for some painful pediatric oncologic procedures such as lumbar puncture (LP) and bone marrow examination (BME).  Several studies mentioned that fentanyl and remifentanyl are often used as anesthetic agent of this procedure, but none of them compare the recovery time of both agent. This study aims to compare the recovery time of fentanyl and remifentanyl in pediatric patients undergoing methoterexate therapy.Subjects and Method: This was a double-blind randomized controlled trial on 36 patients who underwent intratechal methotrexate chemoterapy under general anesthesia anesthesia in pediatric intervention room of Moewardi General Hospital Surakarta that met inclusion criteria. The dependent variable was recovery time and the independent variable were fentanyl and remifentanyl. The samples were divided into 2, Fentanyl (F) and Remifentanyl (R) group. Recovery time was recorded after the procedure until the subject reached Pediatric Glasgow Comma Scale (PGCS) of 15. Statistical analysis was Mann Whitney U Test using SPSS 25 for Windows.Results: The mean recovery time of F group was 373.39 ± 29.48 seconds, while R group was 124.67±11.55 seconds. There was a significant difference in recovery time between patients in the Fentanyl group and the Remifentanyl group (p= 0.000).Conclusion: Remifentanyl recovery time was significantly faster than with fentanyl in pediatric patients undergoing intrathecal methotrexate chemotherapy.Keywords: Fentanyl, Methotrexate, Outpatient anesthesia, Recovery time, RemifentanylCorrespondence: Ferdy Pamungkas. Anesthesiology Department, Moewardi General Hospital, Surakarta. Jalan Kolonel Sutarto 132 Jebres, Kecamatan Jebres, Surakarta City 57126. Central Java, Indonesia. dr.ferdypamungkas@gmail.com. +6281230269501.Indonesian Journal of Medicine (2022), 07(01): 115-121https://doi.org/10.26911/theijmed.2022.07.01.12
Meta Analysis: Correlation between Diabetes Mellitus and Surgical Wound Infection Fahrezi, Chattrin; Murti, Bhisma; Tamtomo, Didik
Indonesian Journal of Medicine Vol. 7 No. 2 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Surgical wound infections complicate 10-20% of operations with a considerable burden of increasing morbidity, mortality, and health care costs. One third of postoperative deaths are associated with surgical wound infections. The risk of surgical site infection is associated with the presence of risk factors for diabetes mellitus. This causes patients undergoing surgery with diabetes mellitus to have a higher risk of developing surgical site infections. This study aims to examine the effect of diabetes mellitus on the incidence of surgical wound infection.Subjects and Method: This research was conducted using a systematic review design and meta-analysis using PRISMA flow diagrams. The article search was conducted by selecting articles published between the years 2000-2022 which were obtained from several databases of PubMed, Google Scholar, Science Direct, and Springer Link. The keywords used to search for articles were “Diabetes Mellitus”, “Surgical Site Infection”, “cohort”, “Diabetes Mellitus” AND “Surgical Site Infection”, “Diabetes Mellitus” AND “Surgical Site Infection” AND “adjusted odd ratio”. The analysis was carried out using RevMan 5.3 software.Results: Meta-analysis of 9 articles of diabetes mellitus (aOR= 2.54; 95% CI= 1.93 to 3.34; p<0.001) affected the incidence of surgical wound infection.Conclusion: Diabetes mellitus increases the incidence of surgical wound infections.Keywords: diabetes mellitus, surgical wound infectionCorrespondence: Chattrin Fahrezi. Masters Program in Public Health, Universitas Sebelas Maret, Jl.Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: chattrinfahrezi311@gmail.com. Mobile: 08812­532292.Indonesian Journal of Medicine (2022), 07(02): 122-130https://doi.org/10.26911/theijmed.2022.07.02.01

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