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Journal of Maternal and Child Health

thejmch
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Published by Universitas Sebelas Maret

ISSN : - EISSN : 25490257 DOI : -

Core Subject : Health,

Medicine & Pharmacology Public Health

Journal of Maternal and Child Health (JMCH) is an electronic, open-access, double-blind and peer-reviewed international journal, focusing on maternal and child health. The journal began its publication on July 11, 2015, and is published four times yearly. JMCH aims to improve the policy, program, service, and practice, as they impact infant, children, mother, women, adolescent, and family health.

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Articles 374 Documents

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Meta-Analysis the Effect of Oral Combination Contraceptive on Hypertension and Stroke Zuhaira, Ulul Azmi; Pamungkasari, Eti Poncorini; Widyaningsih, Vitri
Journal of Maternal and Child Health Vol. 7 No. 5 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: Combined oral contraceptives are a form of contraception that are considered safe and effective for some women, but this does not rule out the possibility that combined oral contraceptives contribute to adverse health effects. Several epidemiological studies have shown that oral contraceptives have adverse effects on women's health. The use of contraceptive pills containing the hormones estrogen and progesterone can cause an increase in blood pressure and also stroke if used continuously. The purpose of this study was to estimate the magnitude of the risk of using combined oral contraceptives on the incidence of hypertension and stroke with a meta-analysis study. Subjects and Method: This was a systematic review and meta-analysis using PRISMA flowchart diagram guidelines. The article search process was carried out between 2007-2022 using 3 databases, including Google Scholar, PubMed, and Science Direct. The keywords used in the database search were “oral contraceptive” OR “contraceptive pills” OR “combined oral contraceptive” AND “hypertension” OR “blood pressure” AND “stroke” AND “women of reproductive age”. The inclusion criteria for full text articles using case control observational methods, articles using English, and articles using multivariate analysis with adjusted Odds Ratio results. Articles that have met the requirements are analyzed using the RevMan 5.3 application. Results: A total of 14 articles with case-control study designs originating from China, Ethiopia, the United States, Italy, and the Netherlands were carried out in a meta-analysis in this study. Meta-analysis of 7 articles showed that the effect of using combined oral contraceptives was to increase the incidence of hypertension 1.44 times compared to those who did not use combined oral contraceptives (aOR= 1.44; 95% CI= 1.12 to 1.84; p= 0.004). Meanwhile, 7 articles showed that the effect of using combined oral contraceptives was to increase the incidence of stroke by 2.08 times compared to those who did not use combined oral contraceptives (aOR= 2.08; 95% CI= 1.48 to 2.92; p < 0.001). Conclusion: Combined oral contraceptives increase the risk of hypertension and stroke. Keywords: combined oral contraceptives, hypertension, stroke, meta-analysis Correspondence:Ulul Azmi Zuhaira. Master’s Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: ululazmizuhaira@gmail.com. Mobile: +6282245012258.

The Utilization of Android-Based Application as a Stunting Prevention E-Counseling Program Innovation during Covid-19 Pandemic Friska, Erlin; Andriani, Helen
Journal of Maternal and Child Health Vol. 6 No. 5 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: Stunting in children is one of the most significant barriers to human development, globally affecting approximately 162 million children under 5 years of age. During the Covid-19 pandemic, the development of communication and information media such as smartphones has encouraged the creation of various kinds of application-based health innovations known as mobile health. The purpose of this study was to analyze the utilization of android-based applications as a stunting prevention e-counseling program innovation in the Covid-19 pandemic era. Subjects and Method: This research was a systematic review. The articles were selected from Google Scholar, PubMed, ScienceDirect, and Elsevier. The keywords for this review are: prevention, education, stunting counseling, Covid-19, android-based stunting prevention application, stunting counseling application during the Covid-19 pandemic, application for stunting, android application for stunting. The search process to exclude the articles used for this literature review using the PRISMA method. Results: The results showed that the existence of an Android-based stunting prevention application innovation can make it easier for the public to monitor health, obtain the education, and provide counseling to health workers. This is in line with government policies during the Covid-19 pandemic which urges the public to limit activities. Conclusion: The conclusion of this study is android-based applications are very friendly if used by the wider community because they can access information anytime and anywhere, are more flexible, and affordable.

Meta-Analysis the Effect of Prenatal Yoga to Lower Anxiety and Stress in Intrapartum Women Wulandari, Adetya; Prasetya, Hanung; Murti, Bhisma
Journal of Maternal and Child Health Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: Pregnant women are very susceptible to complications or high risk during pregnancy, especially before delivery, causing anxiety and stress. Prenatal yoga is known to relax breathing which can relax muscles and reduce anxiety. The purpose of this study was to analyze the effect of prenatal yoga on pregnant women on anxiety and stress in the face of labor. Subjects and Method: This study was a meta-analysis with the following PICO, population: pregnant women. Intervention: prenatal yoga. Comparison: not doing prenatal yoga. Result: reduced stress and anxiety. Keywords to search for articles “Prenatal Yoga” OR “Pregnancy yoga” AND “Anxiety” AND “Stress” AND “randomized controlled trial”. The articles included are full-text English and a randomized controlled trial study design from 2009-2021. Article selection is done by using PRISMA flow diagram. Articles were analyzed using the Review Manager 5.3 application. Results: A total of 12 RCT studies from the Asian, American and European continents were selected for systematic review and meta-analysis. Based on 9 articles stated that pregnant women who do prenatal yoga can reduce anxiety about childbirth by 0.86 times compared to not doing prenatal yoga (SMD = -0.86; 95% CI -1.50 to -0.21; p= 0.010) and 5 articles state that pregnant women those who do prenatal yoga can reduce stress during childbirth by 1.23 times compared to those who do not do prenatal yoga (SMD= -1.23; 95% CI= -1.59 to -0.87; p< 0.001). Conclusion: Prenatal yoga can reduce anxiety and stress in pregnant women in the face of childbirth. Keywords: anxiety, stress, pregnancy, prenatal yoga Correspondence: Adetya Wulandari. Master’s Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Mobile: 081274814357. Email: Adetya1507@gmail.com.

Meta-Analysis the Effect of Obesity and Stress on Menstrual Cycle Disorder Annarahayu, Lutfi; Dewi, Yulia Lanti Retno; Adriyani, Rita Benya
Journal of Maternal and Child Health Vol. 6 No. 4 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: There are many factors that influence menstrual patterns to become irregular, including stress and obesity. Menstrual cycle irregularities can have a serious impact on women's health, which will affect the metabolic, fertility, sexual and reproductive systems. This study aims to analyze the influence of obesity and stress on menstrual cycle disorders with a meta-analysis study. Subjects and Method: This study is a systematic study and meta-analysis, with the following PICO, Population= women of childbearing age. Intervention= obesity and stress. Comparison = not obese and not stressed. Outcome = disruption of the menstrual cycle. The articles used in this study were obtained from several databases, including PubMed, ScienceDirect and Google Scholar. The keywords used are "menstrual disorder and obesity and stress", "obesity and menstrual irregularity", "obesity OR stress AND menstrual irregularity OR cross sectional study". The articles included in this study are full text articles with a cross sectional study design. Articles were collected using PRISMA flow diagrams. Articles were analyzed using the Review Manager 5.3 application. Results: Meta-analysis of 8 observational studies showed that obese women were 4 times more likely to have menstrual cycle disorders than normal weight (aOR= 4.19; 95% CI= 1.99 to 8.84; p= 0.002). Meta-analysis of 6 observational studies showed that women with stress had a risk of experiencing menstrual cycle disorders 1.28 times compared to women who did not experience stress (aOR= 1.28; 95% CI= 1.13 to 1.45; p = 0.001). Conclusion: Obesity and stress affect menstrual cycle disorders.

Effect of Antenatal Betamethasone and Dexamethasone on Maternal Blood Glucose Levels, Fetal Movement, Nst Parameters, and Umbilical Artery Doppler Chaurasia, Amrita; Singh, Vidhi
Journal of Maternal and Child Health Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: The rationale of the study is to establish the time duration of recovery of disturbed sugar values and NST parameters following steroid administration and which drug has a lesser rate of hyperglycemia and lesser disturbance of DFMC and NST parameters, so as to advocate better drugs for fetal lung maturity. This study aims to compare the changes in maternal serum glucose levels, daily fetal movement count, NST parameters, and umbilical artery doppler following Betamethasone and Dexamethasone administration in antenatal women. Subjects and Method: The study design is a prospective observational cohort study. 100 pregnant patients, were recruited into 2 equal groups who received Betamethasone and Dexamethasone in Obstetrics & Gynaecology department, MLN Medical College, Prayagraj. The independent variables are Age, Gravidity, and BMI while the dependent variables are postprandial blood sugar values, Daily Fetal Movement Count, Fetal Heart Rate, Non-Stress Test Parameters, and Doppler Flow Veloci- metry of the Umbilical artery. Categorical variables were compared using the Chi-square test, while, for continuous variables T-test was used. Study instruments include Glucometer, Cardiotocography, and Ultrasound. Results: Significant changes in the glycemic profile and fetal movements were noted. The mean ± SD glucose rise after 24 hrs in Group A (Mean= 140.10; SD= 35.90) and group B (Mean= 113.26; SD= 27.90), with p<0.001. 54% and 24% women perceived reduced fetal movements (p = 0.002) while 14% and 12% women had reduced variability on NST (p = 0.766) in Group A and Group B respectively, with 66.6% and 85.71% showing reduced flow on Doppler. Conclusion: Antenatal Betamethasone as well as Dexamethasone administration causes significant changes in maternal hyperglycemia, FHR, and DFMC at 24hrs while changes were non-significant in NST parameters and Doppler. Maternal hyperglycemia resolved within 72hrs with a resolution of decreased fetal movement perception. Umbilical artery flow decreased 24 hrs following steroid administration with more profound changes with betamethasone.

Increased Plasma Caspase-3 in Children with Down Syndrome is Associated with an Increasing Risk of Pulmonary Hypertension Prasanti, Damayanti Ika; Widjaja, Sri Lilijanti; Rokhayati, Evi
Journal of Maternal and Child Health Vol. 8 No. 1 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: Pulmonary hypertension (PH) is the one of the comorbidities in children with Down syndrome. The pathogenesis of this pulmonary hypertension remains to be investigated, although endothelial dysfunction and apoptotic activity are among the proposed mechanisms. Caspase-3 is a key regulator of apoptosis and appears to be an attractive predictor of pulmonary hypertension in children with Down syndrome. Subjects and Method: A cross-sectional observational clinical study was performed in Dr. Moewardi General Hospital in Surakarta-Indonesia between January and March 2021 involving clinically diagnosed children with Down syndrome. Sampling method was using a consecutive sampling. The independent variable was plasma caspase-3 level and the dependent variable were the presence of pulmonary hypertension and congenital heart defects (CHD). Clinical data documentation, blood collection and echocardiography were performed on enrollment day. We first determined the plasma level of caspase-3 in 36 children with Down syndrome and CHD (n=18) or without CHD (n=18) and further determined the risk of having pulmonary hypertension using the plasma caspase-3 level. We also determined the biomarker performance of caspase-3 using a receiver-operating characteristic (ROC) analysis Results: Children with Down syndrome with PH had a higher plasma caspase-3 compared to those without PH (p<0.001). In those with both CHD and PH, the plasma caspase-3 level was also high although not statistically significant (p=0.145). The highest plasma caspase-3 level was observed in subjects with PH without CHD (p<0.01). Relative risk and ROC analysis demonstrated that increased plasma caspase-3 level increased the risk to have PH 5 times (RR=5.00, 95% CI 1.74 to 14.34; p<0.001) and predicted the incidence of PH in children with Down syndrome (AUC 0.88, CI 0.76 to 0.99). Conclusion: An elevation in plasma caspase-3 level of Down syndrome children is associated with the increasing risk of having PH regardless the presence of CHD. Keywords: pulmonary hypertension; down syndrome; caspase-3; pathogenesis; apoptosis. Correspondence: Damayanti Ika Prasanti. Department of Pediatrics, Faculty of Medicine, Universitas Sebelas Maret / Dr. Moewardi General Hospital. Jl. Kolonel Sutarto 132, Surakarta 57126, Indonesia. Email: damayanti_ip@yahoo.com. Mobile: 081215683462.

Meta-Analysis The Effect of Maternal Obesity on the Risk of Premature Birth and Neonatal Death Wulandari, Fitria; Budihastuti, Uki Retno; Pamungkasari, Eti Poncorini
Journal of Maternal and Child Health Vol. 6 No. 6 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: The prevalence of obesity in women of reproductive age worldwide is increasing by an estimated 20-36%. Increased prevalence of obesity also occurs in pregnant women. Obesity increases the risk of poor pregnancy outcome. This study aims to investigate the effect of maternal obesity on preterm birth and neonatal mortality. Subjects and Method: This was a systematic review and meta-analysis. The articles used were obtained from several databases, including: Google Scholar, Science Direct, Springer Link, Proquest, and Scopus published from 2010 to 2021. The population in this study was pregnant women with an intervention in the form of obesity, comparison in the form of normal BMI, and outcome such as premature birth and neonatal death. The keywords used to search for articles were: (“maternal obesity” OR “maternal BMI”) AND (“premature birth” OR “preterm birth” OR “preterm delivery” OR “preterm labor”) AND (“neonatal mortality” OR “ neonatal death”) AND “adjusted Odds Ratio”, and “maternal obesity” AND (“premature birth” OR “preterm birth” OR “preterm delivery”) AND (“neonatal mortality” OR “neonatal death”) AND “adjusted Odds Ratio ". The article is a full text article with a cross-sectional and cohort study design. Articles were collected using PRISMA flow diagrams and analyzed using the Review Manager 5.3 . application. Results: There were 19 articles reviewed in the study. A meta-analysis of 13 cohort studies showed that obese pregnant women were 1.02 times more likely to have a premature birth when compared to normal BMI pregnant women, but this result was not statistically significant (aOR=1.02; 95% CI=0.93 to 1.13; p=0.630). A meta-analysis of 4 cohort studies showed that maternal obesity increased the risk of neonatal death and was statistically significant (aOR=1.52; 95% CI=1.17 to 1.99; p=0.002). A meta-analysis of 4 cross-sectional studies showed that maternal obesity increased the risk of neonatal death and was statistically significant (aOR=1.44; 95% CI=1.26 to 1.64; p<0.001). Conclusion: Maternal obesity increases the risk of neonatal death which is statistically significant and the risk of preterm birth which is not statistically significant.

A Comparative Study of the Incidence of Hypoglycaemia and Hypocalcaemia in Neonatal Seizures Occurring within 72 Hours of Birth Admitted in NICU at a Tertiary Care Centre Ur Rahman, Zia; S, Abdul Khaleef; S, Md Sajid Basha; D, Murali Krishnaiah
Journal of Maternal and Child Health Vol. 7 No. 2 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: Recognition of hypoglycaemia and hypocalcaemia in Neonatal seizures is important for to prompt diagnosis and therapeutic implications. Study aimed to analyse the incidence of hypoglycaemia and hypocalcaemia in neonatal seizures occurring within 72 hours of birth in 32-37 weeks preterm and term (37-42 weeks) babies. Subjects and Method: A prospective hospital based observational study enrolled total of 105 neonates presenting with seizures activity within 72 hours of birth admitted to NICU of SV Medical College, Tirupati from September 2013 to October 2014. Samples selected by Simple random sampling method. Detailed antenatal, natal and postnatal history including CNS examination were taken and investigations estimated includes complete blood counts and picture, random blood sugar, and serum ionic calcium. The analysis data was chi square test with SPSS for Windows (Ver 20), SPSS Inc. New York. Results: The results was In neonatal seizures occurring within 72 hours of birth, hypoglycaemia (62.9%) was common, more so in preterm babies both hypoglycaemia 9 (37.5%) and combination of hypoglycaemia and hypocalcaemia 9 (37.5%). The association between type of delivery and hypoglycaemia/ hypocalcaemia shown significant different (p=0.002). The association between Birth Weight and hypoglycaemia/ hypocalcaemia shown a very high significant different (p< 0.001). Conclusion: In neonatal seizures occurring within 72 hours of birth, hypoglycaemia (62.9%) was common, more so in preterm babies both hypoglycaemia 09 (37.5%) and combination of hypoglycaemia and hypocalcaemia 09 (37.5%).

Stunting Determinant Analysis in the East Mainland Province of East Nusa Tenggara for the Period of 2017-2021 Picauly, Intje; P Manongga, Stefanus; Adar, Damianus; CH Liufeto, Franchy
Journal of Maternal and Child Health Vol. 7 No. 6 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: The Mainland of Timor, East Nusa Tenggara Province (NTT) has a diverse regional topography with a high prevalence of stunting (>20%). The local government has taken preventive measures. However, the results show a very small reduction in the prevalence of stunting (±2-3%/year). This study aimed to determine the factors that influence the incidence of stunting in the Eastern Mainland Region, NTT Subjects and Method: This data was a cross-sectional study conducted in NTT, from in June to August 2022. A sample of 28 informants who were selected with the following considerations: officials from the Health Office, PUPR Service, Agriculture Service, and Regency/ City BPS data managers for the Eastern mainland region of NTT. The dependent variable was stunting. The independent variables were Availability of Public Health Workers, Infectious infectious diseases, Open defecation behavior, Family income level, Availability of clean water and proper sanitation, Exclusive breastfeeding, Posyandu visits, Program for giving iron tablets to young women, and Administration of Vitamin A. The data were analyzed by linear regression analysis. Results: Factors that influence the incidence of stunting were sanitation factors (b= -2.22; 95% CI= -3.52 to -0.91; p= 0.012), factor of pneumonia infection (b= 0.07; 95% CI= 0.01 to 0.13; p= 0.038), open defecation behavior factor (b= 2.60; 95% CI= 0.99 to 4.21; p= 0.014), and family income level factor (p= -1.21; 95% CI= -1.80 to -5.70; p= 0.009). Conclusion: The incidence of stunting in the East Mainland Region, NTT is influenced by factors: sanitation, pneumonia infection, open defecation behavior; and family income level. Keywords: stunting incidence, eastern mainland, sanitation factors, infectious diseases, pneumonia, open defecation. Correspondence:Intje Picauly, Department of Nutrition, Faculty of Public Health, Universitas Nusa Cendana, Kupang, Nusa Tenggara Timur, Indonesia, Jl. Adi Sucipto Penfui, Penfui, Maulafa, Kupang, Nusa Tenggara Timur. Mobile: +62822-3714-5517. Email: intjepicauly@staf.undana.ac.id.

Overweight and Obesity as Risk Factors of Breast Cancer in Premenopausal and Postmenopausal Women: Meta-Analysis Fadhila, Shofia Nur; Murti, Bhisma; Widyaningsih, Vitri
Journal of Maternal and Child Health Vol. 6 No. 6 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: A woman has an increased risk of breast cancer due to increased exposure to the hormone estrogen during her life due to early menarche, late menopause, and/or the absence of childbearing. Epidemiological data show that menopausal status has a risk factor for breast cancer. The aim of this study was to investigate overweight and obesity as risk factors for premenopausal and postmenopausal breast cancer. Subjects and Method: A systematic review and meta-analysis study was conducted by systematically reviewing articles published from 2010-2021 in the PubMed, Google Scholar, SpringerLink and Science Direct databases with the keywords overweight AND obesity AND "breast cancer" OR "breast carcinoma" AND "premenopausal women", overweight AND obesity AND "breast cancer" OR "breast carcinoma" AND "postmenopausal women". Inclusion criteria included articles in English, full text, using an observational study design, and displaying adjusted odds ratios. Articles were reviewed using PRISMA diagrams and analyzed using Revman 5.3. Results: A meta-analysis of 10 articles concluded that overweight women were 1.35 times more likely to develop premenopausal breast cancer than women with a normal BMI (aOR= 1.35; 95% CI= 0.98 to 1.86; p= 0.070). A meta-analysis of 10 articles concluded that obese women were 1.27 times more likely to develop premenopausal breast cancer than women with normal BMI (aOR= 1.27; 95% CI= 0.95 to 1.69; p= 0.110). A meta-analysis of 9 articles concluded that overweight women had a 1.28 times risk of developing postmenopausal breast cancer compared with women with a normal BMI (aOR= 1.28; 95% CI= 1.00 to 1.63; p= 0.050). A meta-analysis of 11 articles concluded that obese women were 1.52 times more likely to develop postmenopausal breast cancer than women with normal BMI (aOR= 1.52; 95% CI= 1.17 to 1.98; p= 0.002). Conclusion: Overweight and obesity increase the risk of pre-menopausal and postmenopausal breast cancer.

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