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JSFK (Jurnal Sains Farmasi & Klinis)
Published by Universitas Andalas
ISSN : 24077062     EISSN : 24425435     DOI : 10.25077
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Jurnal Sains Farmasi & Klinis (J Sains Farm Klin) adalah jurnal ilmiah di bidang kefarmasian yang diterbitkan oleh Fakultas Farmasi Universitas Andalas bekerjasama dengan lembaga profesi "Ikatan Apoteker Indonesia" (IAI) daerah Sumatera Barat sejak tahun 2014.
Arjuna Subject : -
Articles 509 Documents
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Pharmacy Staff's Recommendations for Self-Medication Requests on Non-Infectious Productive Cough: A Study in Padang City, Indonesia Nasif, Hansen; Andrelva, Cynthia Bella; Sari, Yelly Oktavia
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.264-269.2023

Abstract

Cough is a physiological reflex to liberate the airway from mucus or foreign objects. Many cough medicines in pharmacies require special expertise to select the proper medication according to the patient's condition. This research aims to evaluation recommendations of drugs for non-productive cough for self-medication from pharmacy staff in Kuranji subdistrict, Padang City.  A cross-sectional study with total sampling techniques is used for collecting data. This research uses a structured interview technique with the main question, what medicine would pharmacy staff recommend if an adult patient comes with a productive cough without any symptoms of infection? There are 30 pharmacies in Kuranji subdistrict, but data that meets the inclusion criteria is only from 25 pharmacies because five pharmacies are not willing to be research sites. Those who were willing to take part in this research were 16 pharmacists and nine non-pharmacist staff. Only 37.5% (6 of 16) of correct drug recommendations were given by pharmacists, and 33.3% (3 of 9) of proper drug recommendations were provided by non-pharmacist staff. There are still many things that could be improved in drug recommendations for this case, with a total average of correct administration of only 36%. The proper drug choices were Bromhexin and Acetylcysteine, while other drugs that were incorrectly chosen were drugs that should have been given with a doctor's prescription, branded drugs with more than one active ingredient , herbs or not the drug of choice for now.There are still many mistakes in the medicine choice, with an average total of only 36% accurate recommendations.
Testing the effectiveness of hair growth tonic with cocoa bean extract on mice for physical stability and activity Alfian, Muhammad; Hasanudin, Muhammad Nurul; Maulana, Mochamad Luqni
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.270-279.2023

Abstract

Cocoa is a highly valued plant due to its versatile uses, including being processed into cosmetic products. Hair loss and slow hair growth are common hair-related concerns that can be effectively addressed through the use of hair tonics. Previously, research has shown that cocoa bean can effectively stimulate hair growth when made into a cream. Our research aimed to determine the secondary metabolite content of cocoa beans extract, formulate the extract into a hair growth tonic, and test its physical stability and effectiveness on hair growth in mice. Cocoa beans extracted by maceration method and conducted phytochemical screening. This extract was then used to create three formulations with different extract concentrations of 0.2%, 0.3%, and 0.5%, which were tested for physical stability, including organoleptic properties, homogeneity, pH, and specific gravity. Mice were divided into five treatment groups, hair length growth measurements were taken every week, on the 7th, 14th and 21st days. Six strands of hair were taken from the application area, and their length was measured using a calliper. Results revealed that cocoa seed extract contains flavonoids, alkaloids, tannins, and phenolics. The formula with a 0.3% concentration of cocoa bean extract showed the best physical stability. Hair growth tests on mice showed no significant difference between the 0.3% and 0.5% cocoa bean extract formulas and the positive control in the second week. The 0.3% formula is the best for ensuring good physical stability and promoting hair growth in mice when used twice daily for two weeks
Knowledge and Attitude of Hypertension Patients towards Traditional Medicines: A Cross-sectional Study at Public Health Center, Siak, Riau Husnawati, Husnawati; Dewi, Ratna Sari; Ningsih, Yozi Fiedya; Fitriani, Dewi
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.280-285.2023

Abstract

Hypertension is a significant global concern associated with severe cardiovascular ailments, including stroke, myocardial infarction, cardiac insufficiency, and renal dysfunction. Traditional medicines (TM) represent a potential alternative treatment modality for the management of hypertension. Hence, this study aims to establish the relationship between individuals' knowledge and attitudes about using TM among hypertension patients. This observational research utilizes a descriptive-analytic approach with a cross-sectional design. Validated questionnaires were used to collect the knowledge and attitudes data of respondents. The correlation between knowledge and attitudes was analyzed with the Spearman test using SPSS version 24. A total of 102 respondents were successfully acquired using purposive non-probability sampling. The results of this study indicate a significant statistical relationship between the knowledge and attitudes of hypertensive patients regarding the utilization of TM (p-value 0.000). Furthermore, a moderate positive correlation (rs 0.493) was observed, suggesting that an improvement in knowledge is associated with a corresponding enhancement in the attitude of hypertensive patients towards TM.
Anti-inflammatory activity of An Ethanol Extract of Pucuk Merah (Syzigium myrtifolium Walp.) in vivo Nursyafni, Nursyafni; Rahmawati, Ayu; Indriani, Lusi; Ashari, Dicki Hamed
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.286-292.2023

Abstract

Compared with classical Utilization of medicinal plants with anti-inflammatory properties, it needs to be done to find alternative treatments with relatively more minor side effects, such as Syzygium myrtifolium walp. This study aims to determine the effective dose of ethanol extract of pucuk merah as an anti-inflammatory in 30 male white rats of the Wistar strain. Testing the extract's anti-inflammatory effect was measured by measuring the edema volume on the soles of the rats' feet after being induced with 1% carrageenan with a pletismometer. The test animals were divided into six treatment groups, namely group 1 negative control (Na CMC 1%), group 2 positive control (Na Diclofenac 50 mg/KgBW), group 3 (dose of pucuk merah leaves extract 75 mg/KgBW), group 4 (quantity of pucuk merah leaves extract 100 mg/kgBW), and group 5 (amount of pucuk merah leaves extract 125 mg/kg BW), with observation times of 30, 60, 90, 120, 150, and 180 minutes. The results showed that rats in group 5 with a dose of pucuk merah (125 mg/kgBW) had the best anti-inflammatory effect, with an anti-inflammatory potential of 97% compared to diclofenac sodium.
Evaluating Economic Outcomes: Single-Use Aspirin vs. Aspirin-Clopidogrel in Ischemic Stroke Patients Based on Barthel Index Scores Yosmar, Rahmi; Febiana, Dian; Fitria, Najmiatul
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.293-299.2023

Abstract

Ischemic stroke is a catastrophic disease that causes large costs in Indonesia. The high prevalence of stroke results in  increased morbidity and mortality rates, which will impact the socioeconomic status of stroke patients. Cost Effectiveness Analysis  (CEA) is a method in pharmaco-economics that aims to make decisions regarding the rational choice of therapy and evaluate  the economic impact on ischemic stroke patients. This study aims to determine the Incremental Cost Effectiveness Ratio (ICER)  value of antiplatelet therapy in the aspirin-clopidogrel combination group and the single aspirin group in ischemic stroke patients  treated at the Regional General Hospital. Dr. M. Djamil Padang. The clinical parameter observed was the Barthel Index (BI) value.  This research is a descriptive study with retrospective data collection using medical record data and the Hospital Management  Information System (SIMRS) at RSUD Dr. M.Djamil Padang. The cost data shows the total direct medical costs incurred in treating  ischemic stroke. Based on the results obtained, the Incremental Cost Effectiveness Ratio (ICER) value is IDR (-) 401,302. 71 per  1% increase. In this study it can be concluded that the aspirin-clopidogrel combination has better cost effectiveness than aspirin  alone.
Antibacterial activities of three species of mangrove leaves extract against Staphylococcus aureus and Escherichia coli Rahmawati, Ayu; Nursyafni, Nursyafni; Herly, Moh. Azhari Herly Azhari; Indriani, Lusi; Lovena, Tri Nova; Khairiah, Kinanti Bahy; Aprilia, Indri
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.300-306.2023

Abstract

The increasing incidence of infections and drug resistance has led scientists to seek approaches towards medicinal plants that are potentially effective against many microorganisms. Therefore, this study was planned to assess the antibacterial activity of 3 mangrove species (Scyphipora hydrophylaceae C.F.Gaertn., Lumnitzera littorea (Jack) Voigt and Avicennia alba Blume) against Staphylococcus aureus and Escherichia coli bacteria. This study used the disc diffusion method to measure the diameter of inhibition at several concentrations of mangrove leaf ethanol extracts, namely 15%, 10%, 5%, 2.5%, 1.25% and 0.625% b/v as well as positive control cefadroxil for bacteria and DMSO as negative control. The test results showed that ethanol extracts of mangosteen leave Scyphipora hydrophylaceae C.F.Gaertn and Lumnitzera littorea (Jack) Voigt had a solid response to Escherichia coli bacteria and moderate potential against S. Aureus bacteria—no antibacterial activity against both test bacteria for Avicennia alba mangrove. This study concludes that Scyphipora hydrophylaceae C.F.Gaertn and Lumnitzera littorea (Jack) Voigt have potent antibacterial activity against Escherichia coli, but Avicennia alba has no antibacterial activity.
Analysis of Pharmacists' Knowledge Level on Drug Management with The Availability of Medicine in Community Health Centers in Padang City Juwita, Dian Ayu; Nasif, Hansen; Viviani, Ivana Regita
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.307-313.2023

Abstract

The availability of medicine is one of the factors that can be employed to assess the quality of community health centers and determine customer satisfaction. Pharmacists require a strong foundation in drug management knowledge to ensure the medicine availability. Proficient drug management can enhance the rational use of medications, promote rational prescription practices, and improve drug utilization efficiency. This research aims to ascertain the pharmacist's knowledge level and the availability of medicine while also exploring any potential correlations between pharmacist knowledge and medicine availability. This research adopts a non-experimental study design with cross-sectional data collection. The research sample was selected using purposive sampling techniques, employing a questionnaire to assess pharmacist knowledge levels, as well as Drug Usage Reports and Drug Request Sheets (LPLPO) to evaluate the availability of medicine levels. Data analysis involved the Chi-Square test and Spearman Rank test. The study results indicated that the majority of pharmacists possessed a high level of knowledge (73.7%), while most community health centers have a moderate level of medicine availability (73.7%). The Spearman Rank test revealed no significant correlation between pharmacist knowledge levels and the availability of medicine.
Correlation between Family Support and Health Professional Education on Tuberculosis Patient Compliance at Public Health Centers Tasikmalaya Anshar, Doni; Fadhilla, Genialita; Wulansari, Wulansari
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.314-319.2023

Abstract

Tuberculosis prevalence in Indonesia is still high, as 824,000 people are infected with Tuberculosis (Indonesia Basic Health Research 2022). This shows that Tuberculosis is still difficult to control due to various factors, including patient compliance. Patient compliance can be influenced by family support and health professional’s education about Tuberculosis therapy, which plays an important role in increasing knowledge of correct therapy for patients and families. This study examines the influence of family support and health professional education on tuberculosis patient compliance. This is a descriptive study with the cross-sectional method. Data was collected from 52 Tuberculosis patients who met the inclusion criteria using a questionnaire. The result shows that family support and health professional education had very good scores (84.6% and 46.2%) on Tuberculosis patients. This affects patient compliance is very good (82.7%). Based on correlation results, it shows that there is a direct influence of family support (p-value<0.05). At the same time, there is an indirect influence of health professional education on patient compliance (p-value>0.05). This shows that family support has a greater direct influence than health professional education on tuberculosis patients’ compliance. However, health professionals still play an important role because the patient's family also receives education from health professionals.
Treatment Duration and Drug Regimen Correlation with Side Effects Incidence in Drug-Resistant Tuberculosis (DR-TB) Patients at Pulmonary Hospital Indriani, Lusi; Renitia, Gita Iftitah; Setiani, Lusi Agus
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.320-326.2023

Abstract

The bacteria Mycobacterium tuberculosis causes Drug-Resistant Tuberculosis (DR-TB). Excessive use of drugs canresult in drug resistance with various side effects. This study aimed to analyze the correlation between the treatment duration and drug regimen with the side effects incidence in DR-TB Patients at Pulmonary Hospital Dr. M. Goenawan Partoidigdo (RSPG) Bogor. This is an observational study with a cross-sectional design. Subjects were selected with purposive sampling methods based on inclusion and exclusion criteria. The research showed that DR-TB patients were mostly male (50.2%) with productive age (46.1%). The most common DR-TB treatment experienced by patients in the advanced phase, generally for 9-24 months (75.3%), and the type of drug side effect most experienced was gastrointestinal disorders, that is nausea (55.1%). The use of standard conventional drug regimens mostly in Z, E, Eto, Km, Lfx, Cs (Pyrazinamide, Ethambutol, Ethionamide, Kanamycin, Levofloxacin, Cycloserine) of 51.4%. The chi-square analysis showed no significant correlation between the treatment duration and the incidence of side effects. At the same time, there was a meaningful correlation between the drug regimen (short-term, long-term, and conventional standard regimen) and the side effects incidence. The suspected drugs causing gastrointestinal side effects were pyrazinamide, ethambutol, ethionamide, and levofloxacin. The side effects of arthritic arthralgia were suspected to be caused by pyrazinamide, ethionamide, and levofloxacin.
Self-Medication Pattern among Customers in a Community Pharmacy Almasdy, Dedy
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.327-332.2023

Abstract

Self-medication is a common practice carried out by the community. This practice is increasingly popular due to the increasing number of OTC products being marketed and the increase in public knowledge due to advances in information technology. This cross-sectional research was conducted at a community pharmacy by collecting data using a structured interview approach to document self-medication practices carried out by customers. A total of 285 customers were interviewed. The Mean age was 30.54 years old. The majority of them were female (74.4%), students (57.2%), and had secondary-level education (72.3%). The majority of the customers came to the pharmacy to continue their medicines which were bought before the day of the visit (60.4%). The dominant factor that influenced the customers to buy the medicines was the experience of using previous medicines (34.9%). Related to a question about customer's adherence to drug regimen, the majority of them (71.5%) answered 'always' and 'often', meanwhile to question about customers' practice if the medicine could not produce the desired effect, the majority of them (75%) answered 'stopping the medicines and seeking professional advice's. The total number of medicines that were bought by the customers were 375 items (mean 1.27 + 0.51), consisting of scheduled poison medicines, OTC medicines, vitamin/mineral supplement, and phyto-medica.

Page 44 of 51 | Total Record : 509

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