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All Journal Martabe : Jurnal Pengabdian Kepada Masyarakat JSFK (Jurnal Sains Farmasi & Klinis) JURNAL FARMASIMED (JFM) Jurnal Pengmas Kestra (JPK) AS-SHIHA: JURNAL KESEHATAN Journal Of Pharmacy
Tri Nova Lovena
Pharmacy Study Program, Faculty Of Mathematics, Natural Sciences And Health, University Of Muhammadiyah Riau, Riau-Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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SEMINAR TENTANG PELEMBAB KULIT WAJAH DARI EKSTRAK DAUN NANGKA (ATROCARPUS HETEROPHYLLUS LAM.) Tri Nova Lovena; Aminah S; Nur Ulina M Br Turnip
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 1 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (461.625 KB) | DOI: 10.35451/jpk.v1i1.740

Abstract

One of the Indonesia plant has the potential to produce a natural antioxidannt is nangka leaf containing flavonoids,saponins, tannins.objectives: tomake preparations creamy nangka leaf extract mask. Method the study was conducted experimentally,the sampelwas extracted by maceration for 3x24 hours using 96% ethanol. The results of the viscous extract is obtained as the active substances with concentrations 5% and 10%. Test preparations test organoleptis, include an examination of its homogeneity, ph preparations and skin moisture. Homogeneity test showed that the mask cream preparations produced were homogeneous, pH range 6-7 and the humidity test with a concentration of 5% obtained an average value and could moisturize the skin and a concentration of 10% obtained an average value of 59.46% could moisturize the skin. Jackfruit leaf extract can be formulated in cream mask preparations and cream jackfruit leaf mask extract preparations can moisturize the skin.
Evaluasi Penggunaan Obat Dispepsia Pada Pasien Rawat Jalan Periode Juni-November 2022 Di RSUD Rokan Hulu Nursyafni; Tri Nova Lovena; Ulfha, Ulfha Ikhwani
The Journal Of Pharmacy Vol. 1 No. 2 (2024): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

Dyspepsia is a feeling of discomfort originating from the upper abdomen. The purpose of this study was to evaluate the accuracy of drug use in patients with dyspepsia and the relationship between sociodemographic characteristics, especially age and sex, and risk factors at Rokan Hulu Hospital for the period June–November 2022. This study used a non-experimental descriptive method. Samples were taken from as many as 110 patients. The results showed that the most common patient characteristics were female sex by 66.4% (73 people), the elderly-late age group of 56 years by 30.9% (34 people), patients who did not work by 66.4% (73 people), the drug that was widely used was lansopazole by 48.7% (95 prescriptions), and the class of drug that was widely used was the proton pump inhibitor group by 48.7% (95 prescriptions). On the results of the chi-square test with a significance value of p = 0.05 for the relationship between age, gender, and risk factors, the age value is p = 0.025, while gender is p = 0.000. It was concluded that at Rokan Hulu Hospital, the evaluation of dyspepsia drugs was 100% correct and showed that there was a relationship between age, gender, and risk factors for work. Further research is expected to take observation locations in two or more places as a comparison for more varied results.
Aktivitas Analgesik Ekstrak Etanol Daun Pucuk Merah (Syzygium myrtifolium Walp.) pada Mencit Putih Jantan (Mus musculus) Lusi Indriani; Tri Nova Lovena; Nursyafni; Nawwar Irfan; Alfahtiah Zurlina
The Journal Of Pharmacy Vol. 1 No. 2 (2024): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

Analgesics are substances that reduce or eliminate pain without causing loss of consciousness. Traditional medicines are considered safer than synthetic drugs. One plant with potential as an analgesic is the red shoot plant (Syzygium myrtifolium Walp). This plant contains flavonoids, anthocyanins, phenolics, and triterpenoids. This study aimed to determine the analgesic activity of ethanol extract of red shoot leaves (EPM) in male white mice. The analgesic effect was obtained through the writhing test using 1% glacial acetic acid induction. Twenty male white mice were divided into 5 treatment groups, including negative control (0.5% Na CMC), treatment 1 (EPM 3.7 mg/kgBW), treatment 2 (EPM 7.4 mg/kgBW), and treatment 3 (EPM 14.8 mg/kgBW), and positive control (mefenamic acid 500 mg/70 kgBW). All mice were given treatment according to their respective groups. After 30 minutes, all mice were induced with 1% glacial acetic acid at a dose of 10 ml/kgBW intraperitoneally. Then, the number of writhes was observed every 5 minutes for 60 minutes. The average number of writhes data was analyzed using ANOVA and Tukey HSD tests. The results showed that treatment groups 2 (7.40 mg/kgBW) and 3 (14.80 mg/kgBW) showed analgesic activity in male white mice induced by 1% acetic acid. The best dose was 14.80 mg/kgBW with writhing protection of 34.74% and analgesic efficacy of 45.59% compared to mefenamic acid.
PERAN KOMUNIKASI, INFORMASI, DAN EDUKASI (KIE) DALAM MENINGKATKAN PENGETAHUAN MASYARAKAT TENTANG DIABETES MELITUS DI KAMPUNG HIJAU KOTA BANJARMASIN Andika, Andika; Aryani, Diya; Yulianti, Tri; Indrayudha, Peni; Nissa Ainni, Ayu; Nurul Fadel, M.; Nova Lovena, Tri
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 8, No 8 (2025): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v8i8.%p

Abstract

diabetes melitus (DM) merupakan penyakit kronis yang terus meningkat prevalensinya dan membutuhkan perhatian serius, khususnya dalam aspek pencegahan dan pengelolaan. Tujuan kegiatan pengabdian ini untuk meningkatkan pengetahuan masyarakat Kampung Hijau, Banjarmasin, tentang penyakit DM melalui pendekatan Komunikasi, Informasi, dan Edukasi (KIE) dan juga pendekatan PIO bagi pasien yang memiliki gula darah tinggi dari hasil tes leb. Metode pelaksanaan dilakukan dengan pelaksanaan pengabdian masyarakat secara langsung yang bekerjasama dengan puskesmas Sungai Bilu  dan pemerintah setempat, serta dilakukan pemeriksaan gula darah secara langsung, dilanjutkan konsultasi medis, pemberian obat (PIO) dan dilanjutkan komunikasi informasi dan edukasi (KIE) oleh tenaga kesehatan serta dosen Farmasi dari organisasi APTFMA. Hasil kegiatan menunjukkan peningkatan signifikan dalam pengetahuan masyarakat berdasarkan evaluasi pre-test dan post-test. Masyarakat menjadi lebih memahami gejala, pengobatan, pencegahan,  serta pentingnya pola hidup sehat bagi pasien yang mempunyai gula darah tinggi. Kegiatan ini terbukti efektif dalam meningkatkan kesadaran masyarakat akan pentingnya pengendalian diabetes dan diharapkan dapat menjadi model pemberdayaan kesehatan komunitas berbasis edukasi langsung.
Cytotoxic Activity Testing The Extract of Leaves and Yellow Sirsak Fruit (Annona montana) using Method Brine Shrimp Lethality Test (BSLT) Rahmawati, Noveri; Hari, Dewi Gulyla; Tri Nova Lovena; Nurdina Putri; Rahma Dona; Rahma Cintya Faiza; Amini, Rahmi
The Journal Of Pharmacy Vol. 2 No. 2 (2025): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

The yellow sirsak plant (Annona montana) is an annonaceae family which has been used by the community as traditional medicine properties such as treating diarrhea, vitamin C deficiency and treating boils. This study aims to determine the cytotoxic activity of the larvae of Artemia salina Leach shrimp by using the BSLT method after giving extracts from the leaves and fruit of yellow sirsak (Annona montana). The results showed that the LC50 value of the n- hexane extract of yellow sirsak leaves was 45,84 µg/mL, the ethyl acetate extract of yellow sirsak leaves was 26,44 µg/mL and the ethanol extract of yellow sirsak leaves was 13,99 µg/mL. The n-hexane extract of yellow sirsak fruit was 31,46 µg/mL, the ethyl acetate extract was 40,45 µg/mL and the ethanol extract of the yellow sirsak fruit was 19,84 µg/mL. The mixture of n-hexane leaves and yellow sirsak fruit was 29,91 µg/mL, the ethyl acetate extract mixture of yellow sirsak leaves and fruit was 21,71 µg/mL and the mixture of ethanol extract and yellow sirsak fruit was 14,75 µg/mL. Based on the research results, it can be concluded that the ethanol extract of yellow sirsak leaves shows the most active cytotoxic activity with an LC50 value of 13,99 µg/mL.
Antibacterial activities of three species of mangrove leaves extract against Staphylococcus aureus and Escherichia coli Rahmawati, Ayu; Nursyafni, Nursyafni; Herly, Moh. Azhari Herly Azhari; Indriani, Lusi; Lovena, Tri Nova; Khairiah, Kinanti Bahy; Aprilia, Indri
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.300-306.2023

Abstract

The increasing incidence of infections and drug resistance has led scientists to seek approaches towards medicinal plants that are potentially effective against many microorganisms. Therefore, this study was planned to assess the antibacterial activity of 3 mangrove species (Scyphipora hydrophylaceae C.F.Gaertn., Lumnitzera littorea (Jack) Voigt and Avicennia alba Blume) against Staphylococcus aureus and Escherichia coli bacteria. This study used the disc diffusion method to measure the diameter of inhibition at several concentrations of mangrove leaf ethanol extracts, namely 15%, 10%, 5%, 2.5%, 1.25% and 0.625% b/v as well as positive control cefadroxil for bacteria and DMSO as negative control. The test results showed that ethanol extracts of mangosteen leave Scyphipora hydrophylaceae C.F.Gaertn and Lumnitzera littorea (Jack) Voigt had a solid response to Escherichia coli bacteria and moderate potential against S. Aureus bacteria—no antibacterial activity against both test bacteria for Avicennia alba mangrove. This study concludes that Scyphipora hydrophylaceae C.F.Gaertn and Lumnitzera littorea (Jack) Voigt have potent antibacterial activity against Escherichia coli, but Avicennia alba has no antibacterial activity.
Determination of Total Flavonoid Levels Of Cinnamon Leaf Infusion (Cinnamomum burmanni (Nees & T.Nees) Blume.) Using UV-Vis Spectrofotometry Lovena, Tri Nova; Dewi Gulyla Hari; Encik Juliansyah Arief
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/x2vajr20

Abstract

Background: Cinnamon leaves (Cinnamomum burmanni (Nees & T.Nees) Blume.) are natural plants used as traditional medicine because they have secondary metabolite compounds, namely flavonoids, tannins, saponins, alkaloids, and triterpenoids. Objective: This study aims to determine the total flavonoid compound levels found in cinnamon leaves (Cinnamomum burmanni (Nees & T.Nees) Blume.). Methods:The extraction method used is the infusa method using aquadest solvent. Qualitative analysis used phytochemical screening and quantitative analysis used is by UV Vis Spectrophotometry with standard comparison using quercetin. Results: For parametric data analysis using One Way Annova analysis. The results of phytochemical screening examination of cinnamon leaves (Cinnamomum burmanni (Nees & T.Nees) Blume.) are positive for flavonoid compounds with the total flavonoid compound content using the UV-Vis Spectrophotometry method is 0.5691 mgQE/g, and the results of parametric data analysis using One Way Annova analysis show a significant value of flavonoid content of 1.000> 0.05. This indicates that the flavonoid levels in the sample are relatively stable and homogeneous, so the treatments applied did not result in significant variation. This may suggest that the treatment factors in the study did not significantly affect the amount of flavonoids contained in the cinnamon leaf extract. Thus, the detected flavonoid content is likely more influenced by the natural characteristics of the plant rather than by the treatments tested. Conclusion: The cinnamon leaf (Cinnamomum burmanii) showed a positive result for the presence of flavonoid compounds.
Determination of Flavonoid Content of Ethanol Extract of Yellow Pumpkin Leaves (Cucurbita moschata Dulchesne ) Using Uv-Vis Spectrophotometry Dewi Gulyla Hari; Tri Nova Lovena; Ummul Khairiah
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/3rps7m67

Abstract

Background: Flavonoids are one of the most abundant groups of secondary metabolite compounds found in plant tissues. Pumpkin leaves (Cucurbita moschata Dulchesne ) can generally be used as antidiabetic, analgesic, nephroprotective and anticancer for stomach pain, jaundice, skin infections, lowering cholesterol, and blood sugar levels, and contain flavonoid compounds. Purpose: to determine the levels of flavonoid compounds contained in 70% ethanol extract of pumpkin leaves (Cucurbita moschata Dulchesne ). Methods: using the UV-Vis spectrophotometry method and to determine the flavonoid content from the results of phytochemical screening in the ethanol extract of pumpkin leaves. Pumpkin leaf extract was obtained through maceration techniques with 70% ethanol as the solvent. Results: The study showed that there was flavonoid content in pumpkin leaves, which was orange in color and the results of the study determined the flavonoid levels using UV-Vis spectrophotometry at a wavelength of 428 nm. om the resultsobtained from the measurement of the standard curve of quarcetin, it can be concluded that the higher the concentration used, the higher the absorbance value obtained and it can be seen that the results obtained total flavonoid content in the 70% ethanol extract sample of pumpkin leaves is 7.2672 mgQE/g.  Conclusion: There is a flavonoid compound content contained in pumpkin leaves.
Uji Aktivitas Antiinflamasi Ekstrak Etil Asetat Daun Tumbuhan Akar Kaik-Kaik (Uncaria cordata (Lour.) Merr) pada Tikus Putih (Rattus norvegicus) Jantan Noveri Rahmawati; Gulyla Hari, Dewi; Nurbaiti; Rahmawati, Ayu; Nursyafni; Indriani, Lusi; Lovena, Tri Nova; Arif, Muhammad; Hendri Sandi, Nofri
As-Shiha: Jurnal Kesehatan Vol. 3 No. 1 (2023): As-Shiha: Jurnal Kesehatan
Publisher : Fakultas MIPA dan Kesehatan, Universitas Muhammadiyah Riau

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Abstract

Antiinflammatory activity of ethyl acetate extracts of the leaves of plant Akar Kaik-kaik Uncaria cordata (Lour.) Merr on white male rats. This research examined the quality of crude drugs and extracts ethyl acetate. It is intended to obtain raw materials which can ultimately ensure uniform pharmacologic effect. Antiinflammatory activity of the ethyl acetate extract were tested using the method of paw edema against white male rats. The research were 15 rats mile which divided into 5 groups. Negative control (Na CMC 1%), positive control (Na diklofenak dose 4,5 mg/kgBB) and extract group ethyl acetat with the dose 100, 200 and 400 mg/kgBB given orally. The volume measurement after subcutaneous injection caragen 1% performed with one hour interval for 5 hours assessing with pletysmometer and calculated the inhibition persen. The result of this study showed that the quality of crude drugs and extract ethyl acetate meet the specified requirements Indonesian Herbal Pharmacopoeia. Ethyl acetate extract has significant anti-inflammatory effects to the negative control at doses of 200 and 400 mg/kgBB while against the positive control did not differ significantly white male rats.
Uji Aktivitas Antiinflamasi Ekstrak Etanol Daun Tumbuhan Akar Kaik-Kaik (Uncaria cordata (Lour.) Merr) Terhadap Tikus Putih (Rattus norvegicus) Jantan Tri Nova Lovena; Rahmawati, Noveri
As-Shiha: Jurnal Kesehatan Vol. 2 No. 2 (2022): As-Shiha: Jurnal Kesehatan
Publisher : Fakultas MIPA dan Kesehatan, Universitas Muhammadiyah Riau

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Abstract

The study has been carried out of antiinflammatory activity of ethanol extract leaves of plant akar kaik-kaik (Uncaria cordata (Lour.) Merr of the male white rat (Rattus norvegicus). The ethanol extract was first conducted quality checks extracts include: organoleptic test, Thin Layer Chromatography profiles (TLC), determination of water content, drying shrinkage, and ash content. The results showed the ethanol extract the requirements extracts in general. Further test antiinflammatory activity of the white rat (Rattus norvegicus) males using the paw edema. Animal trials were divided into 5 groups: negative control group Na CMC 1%, a positive control diclofenac sodium 4.5 mg/kg weight of the rat and the ethanol extract dose of 100, 200, and 400 mg/kg weight of the rat, the rats are challenged by a subcutaneous injection of 1% solution of carrageenan into the plantar side of the left hind paw, result showed that the ethanol extract doses of 100, 200 and 400 mg/kg weight of the rat had a significantly antiinflammatory activity (p <0.05).
Co-Authors Alfahtiah Zurlina Aminah S Amini, Rahmi Andika Andika Aryani, Diya AYU RAHMAWATI Encik Juliansyah Arief Hari, Dewi Gulyla Hendri Sandi, Nofri Herly, Moh. Azhari Herly Azhari Indri Aprilia, Indri Indriani, Lusi Khairiah, Kinanti Bahy Lusi Indriani Muhammad Arif Nawwar Irfan Nissa Ainni, Ayu Noveri Rahmawati Nur Ulina M Br Turnip Nurbaiti Nurdina Putri Nursyafni Nursyafni, Nursyafni Nurul Fadel, M. Peni Indrayudha Rahma Cintya Faiza Rahma Dona Tri Yulianti, Tri Ulfha, Ulfha Ikhwani Ummul Khairiah