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Jambura Journal of Health Sciences and Research
Published by Universitas Negeri Gorontalo
ISSN : 26230674     EISSN : 2655643X     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health
Jambura Journal of Health Sciences and Research is a health scientific journal which published original articles of public health. This articles Published Twice a year in January and July. Which Focus and Scope in public health issues, including : Epidemiology, Health Education and Promotion, Environmental Health, Occupational Health and Safety, Health Administration and Policy, Biostatistics, Reproductive Health, Hospital Management, Nutrition Science, Health Information System. Moreover, Author can submit articles on any issue relating to public health with editor consideration.
Arjuna Subject : -
Articles 352 Documents
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EXCLUSIVE BREASTFEEDING FOR WORKING MOTHERS AND WORKPLACE LEADERSHIP SUPPORT Hadina Hadina; Hadriani Hadriani; Nirma Nirma; Mardiani Mangun; Putri Mulia Sakti
Jambura Journal of Health Sciences and Research Vol 4 (2022): SPECIAL EDITION JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v4i0.13384

Abstract

Air susu ibu (ASI) merupakan makanan terbaik bagi bayi karena kandungan zat gizinya yang lengkap dan sesuai dengan kebutuhan bayi. Cakupan pemberian air susu ibu (ASI) eksklusif di Puskesmas Tagolu tahun 2020 masih rendah sebesar 36%, faktor penyebab rendahnya cakupan ASI eksklusif karena ibu bekerja sebagai pegawai honorer, Pegawai Negri Sipil (PNS), swasta. Tujuan penelitian ini diketahui hubungan pekerjaan ibu dan dukungan pimpinan tempat kerja dengan pemberian ASI eksklusif. Metode Penelitian observasional analitik dengan metode kuantitatif. Populasi seluruh ibu bekerja yang memiliki bayi usia 6-24 bulan. Jumlah sampel sebesar 24 responden. Instrumen yang digunakan adalah kuisioner. Analisis data univariat dan bivariat dengan uji chi square. Hasil uji statistik chi square diketahui hubungan pekerjaan ibu dengan pemberian ASI dengan nilai p-value = 0,194 (p0,050) berarti tidak signifikan sedangkan hasil uji statistik hubungan dukungan pimpinan dengan pemberian ASI eksklusif diketahui nilai p-value = 0,047 (p0,050) yang menunjukkan adanya hubungan yang signifikan antara dukungan pimpinan dengan pemberian ASI eksklusif. Kesimpulan penelitian tidak ada hubungan pekerjaan ibu dengan pemberian ASI eksklusif dan ada hubungan dukungan pimpinan dengan pemberian ASI eksklusif. Kata Kunci          : ASI eksklusif, Dukungan Pimpinan, Ibu Bekerja. AbstrackMother's milk (ASI) is the best food for babies because of its complete nutritional content and in accordance with the baby's needs. The coverage of exclusive breastfeeding (ASI) at the Tagolu Health Center in 2020 was still low at 36%, a factor causing the low coverage of exclusive breastfeeding because the mother worked as an honorary employee, Civil Servant (PNS), private sector. The purpose of this study was to determine the relationship between mother's work and workplace leadership support with exclusive breastfeeding. Methods Analytical observational research with quantitative methods. The population is all working mothers who have babies aged 6-24 months. Samples 24 respondents. The instrument used is a questionnaire. Analysis of univariate and bivariate data with chi square test. The results of the relationship between mother's work and breastfeeding tha p-value = 0.194 (p 0.050) means that it is not significant and the relationship between leadership support and exclusive breastfeeding the p-value = 0.047 (p 0.050) which indicates a significant relationship between leadership support and exclusive breastfeeding. The conclusion of the study is that there is no relationship between mother's work and exclusive breastfeeding and there is a relationship between leadership support and exclusive breastfeeding. Keywords: Exclusive breastfeeding, Leadership Support, Working Mother.
THE PRESENCE OF Candida albicans IN URINE OF DIABETES MELLITUS AT BHAYANGKARA HOSPITAL PALEMBANG Witi Karwiti; Asrori Asrori; Ardiya Garini; Bayu Meilanda Akbar
Jambura Journal of Health Sciences and Research Vol 4 (2022): SPECIAL EDITION JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v4i0.13070

Abstract

Abstrak Penyakit diabetes mellitus merupakan penyakit degeneratif yang disebabkan oleh kadar glukosa darah puasa yang melebihi 110 mg/dl. Jika konsentrasi glukosa darah melebihi 160 sampai 180 mg/dl, maka glukosa akan keluar bersama urin. Keadaan ini disebut dengan glukosuria. Glukosuria memicu infeksi Candida albicans dan dapat menimbulkan abses ginjal, abses perirenal, infeksi hepar, meningitis, dan lain-lain. Penelitian bertujuan untuk mengetahui keberadaan Candida albicans pada urin penderita diabetes mellitus di Rumah Sakit Bhayangkara Palembang. Jenis penelitian adalah deskriptif dengan pendekatan cross-sectional. Metode pemeriksaan glukosuria dengan carik celup, sedangkan pemeriksaan jamur Candida albicans menggunakan metode Germ-tube test. Besar sampel adalah 45 penderita diabetes mellitus yang diambil dengan teknik purposive samplimg.Hasil penelitian didapatkan dari 45 penderita diabetes mellitus, sebanyak 9 (20%) positif Candida albicans dan 36 (80%) negatif Candida albicans. Berdasarkan umur, dari 29 penderita diabetes mellitus berumur 60 tahun, didapatkan 3 (10,3%) positif Candida albicans. Berdasarkan jenis kelamin, dari 24 penderita diabetes mellitus berjenis kelamin perempuan, didapatkan 7 (29,2%) penderita positif Candida albicans. Hasil pemeriksaan glukosuria positif, dari 13 penderita, sebanyak 4 (30,8%) penderita positif Candida albicans. Penderita  dengan penyakit tidak terkontrol, dari 22 penderita sebanyak 3 (13,6%) penderita positif Candida albicans. Hasil uji statistik menggunakan Chi-square didapatkan, ada hubungan yang signifikan antara umur dengan keberadaan jamur Candida albicans pada urin penderita diabetes mellitus (pValue=0,050). Sedangkan untuk variabel jenis kelamin (pValue=0,143), pemeriksaan glucosuria (pValue=0,411) dan pengontrolan penyakit (pValue=0,459) tidak  ada hubungan yang signifikan (pValue0,05). Dengan demikian, disarankan penderita diabetes mellitus untuk selalu mengontrolkan penyakitnya agar mencegah infeksi Candida albicans.  Kata kunci: Candida albicans, Penyakit Diabetes Mellitus, Germ-tube test, Urin   Abstract              Diabetes mellitus is a degenerative disease caused by blood sugar level is more than 110 mg/dl. If blood sugar level is more than 160 until 180 mg/dl, glucose will be excreted in urine. This situation called glucosuria. Glucosuria triggers Candida albicans infection and causes kidney abscess, perirenal abscess, hepar infection, meningitis, etc. The purpose of this study was to know the presence of Candida albicans in urine of diabetes mellitus patients at Bhayangkara Hospital Palembang. The type of this study was descriptive with cross-sectional approach. The technique of glucosuria test was dip stick, while the method of Candida albicans is Germ-tube test. The sampel size was 45 diabetes mellitus patients collected by purposive sampling technique.                 The research result showed from 45 diabetes mellitus patients, there were 9 (20%) diabetes mellitus patients positive Candida albicans and 36 (80%) negative Candida albicans. Based on age, from 29 diabetes mellitus in patients aged 60 years, there were 3 (10,3%) positive Candida albicans. Based on sex, from 24 women diabetes mellitus patients, there were 7 (29,2%) positive Candida albicans. Based on glucosuria test, from 13 diabetes mellitus patients positive glucosuria, there were 4 (30,8%) positive Candida albicans. Based on disease control, from 22 diabetes mellitus patients with uncontrolled disease, there were 3 (13,6%) positive Candida albicans. The results of statistical tests using Chi-square were obtained, there was a significant relationship between age and the presence of the fungus Candida albicans in the urine of patients with diabetes mellitus (pValue = 0.050). Meanwhile, for the variables of sex (pValue=0,143), glucosuria examination (pValue=0,411) and disease control (pValue=0,459) there was no significant relationship (pValue 0.05). Therefore, it is hoped that diabetes mellitus patients to always control the disease to prevent Candida albicans infection.
HEART DISEASE RISK FACTORS IN ADOLESCENT WOMEN Siti Choirul Dwi Astuti; Nancy Olii
Jambura Journal of Health Sciences and Research Vol 4, No 2 (2022): JULI: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v4i2.13434

Abstract

AbstrakPenyakit jantung penyebab kematian nomor satu pada wanita. Tetapi kenyataannya hanya sedikit wanita yang mengetahui faktor risiko penyakit jantung. Metode yang digunakan studi literatur dengan mencari artikel di situs ilmiah seperti ScienceDirect, Pubmed, Elsiver, NCBI, DOAJ, Proquest, Microsoft Academic, Sage Journal, Oxford Academic, LIPI, ResearceGate, JSTOR dan Scrib.id s menggunakan kata kunci women dan heart disease  sehingga didapatkan 37 artikel dari tahun 2018 sampai dengan tahun 2022. Kebaruan penelitian ini yaitu meneliti tentang faktor risiko penyakit jantung pada remaja putri. Tujuan  dari penelitian ini mengetahui faktor risiko yang menyebabkan wanita mengalami penyakit jantung dan hambatan menerapkan perilaku jantung sehat pada wanita. Hasilnya wanita mengalami penyakit jantung ketika mereka remaja mempunyai persepsi kalau penyakit jantung hanya dialami oleh orang tua dan beransumsi penyakit jantung banyak diderita oleh pria.  Selain faktor tersebut norma sosial juga menjadi penyebab penyakit jantung pada wanita karena  wanita lebih fokus pada  berat badan. Faktor yang menjadi hambatan wanita dalam menerapkan perilaku jantung sehat  antara lain stress dan kurangnya waktu. Karena wanita akan menyadari mereka beresiko mengalami penyakit jantung pada dirinya jika jantung ada masalah sejak awal. Kesimpulannya berat badan, norma sosial dan persepsi tentang penyakit jantung berkontribusi pada rendahnya kesadaran faktor risiko penyakit jantung di kalangan remaja putri sehingga membatasi untuk menerapkan perilaku jantung sehat.Kata kunci:  Jantung; Norma Sosial; Persepsi.  AbstractHeart disease is the number one cause of death in women. But the truth is that few women know the risk factors for heart disease. The method used is to study literature by searching for articles on scientific sites such as ScienceDirect, Pubmed, Elsiver, NCBI, DOAJ, Proquest, Microsoft Academic, Sage Journal, Oxford Academic, LIPI, ResearceGate, JSTOR and Scrib.id s using the keywords women and heart disease so that 37 articles were obtained from 2018 to 2022. The novelty of this study is to examine the risk factors for heart disease in young women. The purpose of this study is to determine the risk factors that cause women to experience heart disease and barriers to implementing heart-healthy behaviors in women. As a result, women experience heart disease when they are teenagers, they have the perception that heart disease is only experienced by the elderly and that many heart disease suffer from men.  In addition to these factors, social norms are also the cause of heart disease in women because women are more focused on weight. Factors that hinder women in implementing heart-healthy behaviors include stress and lack of time. Because women will realize they are at risk of having heart disease on them if the heart has a problem in the first place. In conclusion, weight, social norms and perceptions about heart disease contribute to the low awareness of heart disease risk factors among young women thus limiting to implementing heart-healthy behaviorsKeywords: Heart; Social Norm; Perception.
LECTURES AND YOUTH KNOWLEDGE ON REPRODUCTIVE HEALTH Magdalena Tompunuh; Sri Sujawaty; Odi Lodya Namangdjabar
Jambura Journal of Health Sciences and Research Vol 4, No 3 (2022): OKTOBER: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v4i3.13439

Abstract

Remaja merupakan peralihan dari masa kanak-kanak menjadi dewasa yang artinya, proses pengenalan dan pengetahuan kesehatan reproduksi sebenarnya sudah dimulai sejak dini. Menurut data Kemenkes, angka kehamilan pada remaja umur 15-19 tahun sebesar 1,97%. Angka kematian ibu di Gorontalo tercatat dialami ibu yang masih remaja. Menurut studi pendahuluan, masih ada remaja yang tidak melanjutkan pendidikan dasar di SMP karena terlibat pernikahan dini. Pendidikan kesehatan reproduksi banyak diberikan melalui ceramah. Tujuan penelitian ini adalah untuk mengidentifikasi pengetahuan remaja tentang kesehatan reproduksi. Adapun sampel penelitian diambil menggunakan teknik purposive sampling sebanyak 30 orang remaja.  Instrumen yang digunakan adalah kuesioner yang diberikan sebelum dan sesudah pemberian pendidikan kesehatan reproduksi. Analisis data menggunakan uji Wilcoxon dengan hasil p value sebesar 0,001 lebih kecil dari alpha 0,005 yang berarti ada pengaruh metode ceramah terhadap pengetahuan remaja tentang kesehatan reproduksi. Diharapkan remaja bisa membentuk kelompok sebaya untuk menghidupkan kegiatan konseling pada remaja.Kata kunci: Ceramah; Kesehatan; Pengetahuan; Reproduksi; Remaja.AbstractAdolescence is a transition from childhood to adulthood, which means that the process of introduction and knowledge of reproductive health has actually started from an early age. According to data from the Ministry of Health, the pregnancy rate for adolescents aged 15-19 years is 1.97%. The maternal mortality rate in Gorontalo is recorded to be experienced by mothers who are still teenagers. According to a preliminary study, there are still teenagers who do not continue their basic education in junior high school because they are involved in early marriage. Adolescent reproductive health education is mostly given throughs lectures. The purpose of this study was to identify adolescent knowledge about reproductive health. The research sample was taken using a purposive sampling technique as many as 30 teenagers. The instrument used is a questionnaire given before and after the provision of reproductive health education. Data analysis used the Wilcoxon test with p value of 0.001 smaller than alpha 0.005, which means that there is an influence of the lecture method on adolescent knowledge about reproductive health. It is hoped that teenagers can form peer groups to turn on counseling activities for teenagers.
FACTORS ASSOCIATED WITH STUNTING INCIDENCE IN TODDLERS IN NORTH KALIMANTAN Nurul Hidayatun Jalilah; Ririn Ariyanti; Selvia Febrianti
Jambura Journal of Health Sciences and Research Vol 4 (2022): SPECIAL EDITION JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v4i0.12596

Abstract

Stunting is a condition where the height index for age is below minus 2 standard deviations based on WHO standards. Stunting is caused by the impact of nutritional deficiencies during the first thousand days of life. The purpose of this study was to determine the factors associated with the incidence of stunting in children aged 9-59 months. The type of this research is quantitative, observational analytic study with cross-sectional design. A total of 120 samples were selected by simple random sampling. This research was conducted from August to September 2021. Data was collected by measuring height, interviews and filling out questionnaires. Statistical analysis using Chi-square test and multiple logistic regression. The results showed that the proportion of stunting was 44,2% and normal was 55,8%. The results of the statistical test showed that there was a significant relationship between early complementary feeding, water sources, and place of residence with the incidence of stunting. This study suggests that the government, health agencies, communities and related parties collaborate to implement government policies to reduce the risk of stunting. For health education, it is recommended to be involved in providing health education in the form of counseling that can prevent stunting.
CHARACTERISTICS OF ACCEPTORS WITH THE USE OF IUD CONTRACEPTIVE Fatmawati Ibrahim; Eka Rati Astuti; Juli Gladis Claudia; Selvi Mohamad; Nancy Olii
Jambura Journal of Health Sciences and Research Vol 4 (2022): SPECIAL EDITION JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v4i0.13440

Abstract

Abstrak Masalah kependudukan di Indonesia adalah jumlah penduduk yang besar, laju pertumbuhan penduduk yang tinggi, persebaran penduduk yang tidak merata, struktur demografi yang masih muda, dan kualitas penduduk yang masih memiliki ruang untuk perbaikan. IUD (non hormonal) merupakan jenis alat kontrasepsi jangka panjang yang ideal untuk mencegah kehamilan. Jenis penelitian yang digunakan adalah penelitian observasional analitik dengan pendekatan cross sectional study. Sampel diambil secara total sampling dengan jumlah sampel adalah seluruh akseptor KB yang berkunjung dalam wilayah kerja Puskesmas Dulalowo Kecamatan Kota Tengah Kota Gorontalo dari bulan Januari – Desember 2020 sebanyak98orang. Analisis data yang digunakan adalah Chi Square. Hasil menunjukkan nilai ρ masing-masing karakteristik sebagai berikut: usia (nilai ρ = 0,088), pendidikan (nilai ρ = 0,032), ekonomi (nilai ρ = 0,009), dan paritas (nilai ρ = 0,041). Jadi, karakteristik yang berhubungan dengan penggunaan KB IUD adalah pendidikan, ekonomi, dan paritas. Kata kunci: Akseptor, IUD, Karakteristik, KB Abstract Population problems in Indonesia are a large population, high population growth rate, uneven population distribution, a young demographic structure, and the quality of the population that still has room for improvement. The IUD (non-hormonal) is a type of long-term contraceptive that is ideal for preventing pregnancy. The type of research used is analytic observational research with a cross sectional study approach. The sample was taken by total sampling with the total sample being all family planning acceptors who visited the working area of the Dulalowo Health Center, Kota Tengah Subdistrict, Gorontalo City from January - December 2020 as many as 98 people. Analysis of the data used is Chi Square. The results show the value of each characteristic as follows: age (ρ value = 0.088), education (ρ value = 0.032), economy (ρ value = 0.009), and parity (ρ value = 0.041). So, there characteristics related to the use IUD family planning are education, economy, and parity.          
THE EFFECT OF THE EFFECTIVENESS OF GIVING EFFECTIVE DEEP BREATHING AND COUGHING TECHNIQUES ON AIRWAY CLEANLINESS IN CHILDREN WITH ARI AT THE CIKETING UDIK HEALTH CENTER Restu Iriani
Jambura Journal of Health Sciences and Research Vol 4, No 3 (2022): OKTOBER: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v4i3.14130

Abstract

Sulitnya anak usia sekolah mengeluarkan sekret menjadi pemicu utama anak yang mengalami Infeksi Saluran Pernafasan Akut, upaya untuk membersihkan jalan nafas yaitu dengan cara nafas dalam dan batuk efektif. Kebaruan dalam penelitian ini adalah untuk meneliti pengaruh  keefektifan  pemberian teknik nafas dalam dan batuk efektif terhadap kebersihan jalan nafas pada anak penderita ISPA. Tujuan penelitian untuk meneliti pengaruh  keefektifan  pemberian teknik nafas dalam dan batuk efektif terhadap kebersihan jalan nafas pada anak penderita ISPA di Puskesmas Ciketing Udik. Pengambilan sampel menggunakan tehnik Quota sampling, jumlah sampel 6 responden dengan pertimbangan sampel tersebut telah memenuhi kriteria peneliti. Intervensi yang dilakukan adalah nafas dalam dan batuk efektif  3 kali sehari (pagi, siang dan sore) selama 3 hari, Instrumen yang digunakan adalah Lembar observasi dan SOP nafas dalam dan batuk efektif. Hasil penelitian berdasarkan karakteristik usia didapatkan usia 6 Tahun berjumlah 3 anak (50%) dan usia 8 tahun berjumlah 3 anak (50%), Hasil karakteristik jenis kelamin didapatkan jenis kelamin laki – laki berjumlah 3 anak (50%) dan Jenis kelamin perempuan berjumlah 3 anak (50 %), kebersihan jalan nafas sebelum pemberian nafas dalam dan batuk efektif kategori tidak bersih 6 pasien (100%). Setelah pemberian nafas dalam dan batuk efektif didapatkan hasil kategori bersih 4 pasien (67,3%) dan kategori tidak bersih 2 pasien (33,3%). Kesimpulan penelitian yaitu nafas dalam dan batuk efektik berpengaruh meningkatkan kebersihan jalan nafas pada anak usia sekolah dengan ISPA di Puskesmas Ciketing Udik.Kata kunci : Teknik Nafas Dalam; ISPA ; Anak.AbstractThe difficulty of school-age children expelling secretions is the main trigger for children experiencing acute respiratory infections, efforts to clear the airway by deep breathing and effective coughing. The novelty of this study was to examine the effect of effective deep breathing and coughing techniques on airway hygiene in children with ARI at the Ciketing Udik Health Center. The purpose of this study was to examine the effect of effective deep breathing and coughing techniques on airway hygiene in children with ARI at Ciketing Udik Public Health Center. Sampling using the Quota sampling technique, with a sample of 6 respondents, the application is deep breathing and effective coughing 3 times a day (morning, afternoon and evening) for 3 days, the instruments used are observation sheets and SOPs for deep breathing and effective coughing. Outcomes Evidence-based nursing practice. The results of the application of evidence-based nursing practice based on age characteristics obtained were 3 children (50%) 6 years old and 3 children (50%) 8 years old. There were 3 children (50%) of female sex, cleanliness of the airway before giving deep breaths and effective coughing in the unclean category of 6 patients (100%). After giving deep breaths and effective coughing, the results obtained in the clean category of 4 patients (67.3%) and the unclean category of 2 patients (33.3%). The conclusion of the study is that deep breathing and effective coughing have an effect on improving airway hygiene in school-age children with ARI at the Ciketing Udik Health Center.
TEST THE EFFECTIVENESS OF SENGGANI LEAF EKSTRACT (Melastoma candidum D.Don) AGAINST Propionibacterium acnes suryana ayu lestari; meldawati meldawati
Jambura Journal of Health Sciences and Research Vol 4, No 3 (2022): OKTOBER: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v4i3.13830

Abstract

Senggani (Melastoma candidum D.Don) merupakan tanaman liar yang mengandung beberapa senyawa aktif yang dapat dimanfaatkan sebagai antibakteri. Kebaruan dalam penelitian ini adalah melakukan uji efektivitas ekstrak daun senggani (melastoma candidum d.don) terhadap propionibacterium acnes. Tujuan penelitian ini untuk mengetahui daya hambat ekstrak daun senggani terhadap bakteri Propionibacterium acnes. Ekstrasi dilakukan dengan cara maserasi dengan menggunakan pelarut etanol 96%. Jenis penelitian ini merupakan penelitian eksperimental dengan metode difusi cakram. Perlakuan diulang sebanyak 4 kali dengan konsentrasi 20%, 40%, 60%, 80%, dan 100%, sebagai kontrol positip digunakan clindamycin dan DMSO (Dimethyl sulfoxide) sebagai kontrol negatif. Hasil skrining fitokimia menunjukkan bahwa daun senggani mengandung senyawa, saponin, flavonoid, fenol, tannin, steroid, dan terpenoid. Hasil yang diketahui bahwa ekstrak daun senggani memiliki kemampuan menghambat pertumbuhan bakteri Propionibacterium acnes terlihat dengan adanya zona hambat yang terbentuk. Konsentrasi yang paling efektif menghambat pertumbuhan Propionibacterium acnes yaitu konsentrasi 100% sebesar 16,37 mm. Daun senggani memiliki daya hambat dalam menghambat pertumbuhan bakteri Propionibacterium acnes. Konsentrasi yang paling efektif adalah konsentrasi 100% sebesar 16,37 mm.Kata kunci: Melastoma candidum D.Don; Propionibacterium acnes; antibakteri; ekstrak ABSTRACTSenggani (Melastoma candidum D.Don) is a wild plant that contains several active compounds that can be used as antibacterial. The novelty in this research is to test the effectiveness of senggani leaf extract (Melastoma candidum d.don) against Propionibacterium acnes. The purpose of this study was to determine the inhibition of senggani leaf extract against Propionibacterium acnes bacteria. Extraction is done by maceration using 96% ethanol solvent. This type of research is an experimental study with disk diffusion method. The treatment is repeated 4 times with concentration 20%, 40%, 60%, 80%, and 100%, as a positive control used clindamycin and DMSO (Dimethyl sulfoxide) as a negative control. Phytochemical screening results showed that senggani leaves contain compounds, saponins, flavonoids, phenols, tannins, steroids, and terpenoids. The results are known that senggani leaf extract has the ability to inhibit the growth of Propionibacterium acnes bacteria seen in the presence of inhibitory zones formed. The most effective concentration to inhibit the growth of Propionibacterium acnes is 100% concentration of 16.37 mm. Senggani leaves have inhibitory power in inhibiting the growth of Propionibacterium acnes bacteria. The most effective concentration is a 100% concentration of 16.37 mm.
EFFECT OF ETHANOL EXTRACT OF ROSELLA FLOWER PETALS (HIBISCUS SABDARIFFA LINN) ON THE PHAGOCYTOSIS ACTIVITY OF RAT MACROPHAGES (SPRAGUE DAWLEY) Juliyanty Akuba
Jambura Journal of Health Sciences and Research Vol 4, No 3 (2022): OKTOBER: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v4i3.13353

Abstract

Imunitas merupakan perlindungan terhadap penyakit lebih spesifik terhadap perlindungan infeksi. Kebaruan penelitian ini karena meneliti pengaruh pemberian ekstrak etanol kelopak bunga rosella (Hibiscus Sabdariffa Linn) terhadap aktivitas fagositosis makrofag tikus (Sprague Dawley). Tujuan penelitian untuk mengetahui efek ekstrak etanol kelopak bunga rosella terhadap aktivitas fagositosis, sekresi Nitrit Oksida, sekresi Reactive Oxygen Intermediate, ekspresi IL-12 makrofag tikus yang diinduksi  DMBA pada hari ke-7 dan hari ke-34. Tikus betina galur SD sebanyak 45 ekor dibagi menjadi 5 kelompok, masing-masing kelompok terdiri dari 9 ekor tikus, kelompok baseline, kelompok DMBA 15 mg/ tikus dosis tunggal melalui intragastric dan kelompok perlakuan yaitu diberi EEKBR 10, 50 dan 100 mg/kg BB. Induksi DMBA secara peroral dosis tunggal pada hari pertama penelitian dan EEKBR diberikan setiap hari selama penelitian. Diamati pemberian jangka pendek dan jangka panjang selama 6 hari dan 33 hari, pada hari ke-7 dan hari ke-34 dilakukan pembedahan. Uji aktivitas fagositosis dilakukan dengan uji latex. Sekresi NO dilakukan dengan metode Griess assay. Sekresi ROI dilakukan dengan metode NBT, dan Ekspresi IL-12 dilakukan dengan metode imunositokimia. Data dianalisis dengan Anova satu lengan, kemudian dilanjutkan dengan uji post hoc LSD dan Kurskal-Wallis, kemudian dilanjutkan dengan uji Mann-whitney. Hasil penelitian aktivitas fagositosis makrofag menunjukkan perbedaan yang signifikan antara kelompok DMBA dengan kelompok EEKBR dosis 10, 50 dan 100 mg/kg BB hari ke-7 dan ke-34. Pada pemeriksaan sekresi NO makrofag terdapat perbedaan yang signifikan antara kelompok DMBA dengan kelompok EEKBR dosis 100 mg/kg BB hari ke-7 dan dosis 10, 50 dan 100 mg/kg BB hari ke-34. Pada pemeriksaan sekresi ROI makrofag terdapat perbedaan yang signifikan antara kelompok DMBA dengan kelompok EEKBR dosis 10, 50 dan 100 mg/kg BB hari ke-7 dan ke-34. Kesimpulan EEKBR dapat meningkatkan aktivitas fagositosis, sekresi NO, sekresi ROI dan ekspresi IL-12 makrofag peritoneum tikus yang diinduksi DMBA.Kata kunci: Aktivitas Fagositosis; DMBA; IL-12; Makrofag.AbstractImmunity is protection against disease, more specifically to the protection against infection. DMBA was reported to have immunosuppressive effect. The novelty in this study is the effect of giving ethanol extract of Rosella flower petals (Hibiscus Sabdariffa Linn) on the phagocytic activity of rat macrophages (Sprague Dawley). The objective of this study were to determine the effects of roselle (Hibiscus sabdariffa Linn.) calyx ethanolic extract on the phagocytic activity of macrophage on DMBA induced SD rat on 7 and 34 days.SD female rats by 45 strains were divided into 5 groups, each group consisting of 9 rats; baseline group, group DMBA 15 mg / rat single dose. Treatment group was given EEKBR 10, 50 and 100 mg / kg. The duration treatment of extract was 6 days and 33 days. DMBA were induced by oral administration single dose on the first day of treatment and EEKBR treatment daily the treatment. Phagocytic activity test was conducted using latex. Data were analyzed with one-way ANOVA, followed with LSD analized and Kruskal-wallis followed with Mann-whitney analized.The results showed that phagocytic activity macrophages showed significant differences between the groups with the DMBA and EEKBR dose 10, 50 and 100 mg/kgBW for 7 and 34 days. Total flavonoid anthocyanin levels obtained 2,465% and total polyphenol content obtained 6,03 g GAE/100 g extract.
EMPLOYEE DISCIPLINE, MOTIVATION OF COMPETENCE AND ADMINISTRATION EMPLOYEE PRODUCTIVITY AND FINANCE IN RS. MH. THAMRIN SALEMBA INTERNATIONAL Kurniati Nawangwulan
Jambura Journal of Health Sciences and Research Vol 4, No 3 (2022): OKTOBER: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v4i3.14135

Abstract

Abstrak Kunjungan pasien dalam bulan September – Oktober 2012 belum mencapai target yang diinginkan oleh pemilik RS.MH.Thamrin Internasional Salemba yaitu 300 pasien yang berobat tiap bulannya sedangkan yang dicapai dari divisi marketing hanya 145 pasien yang berobat pada bulan Oktober 2012 ada 5 pegawai yang mengundurkan diri dari admission rekam medis RS.MH.Thamrin Internasional Salemba. Penelitian ini bertujuan untuk mengetahui pengaruh langsung dan tidak langsung disiplin kerja, kompetensi dan motivasi terhadap produktivitas pegawai administrasi dan keuangan RS MH Thamrin Internasional Salemba. Penelitian ini di lakukan di RS MH.Thamrin sampel 64 orang menggunakan data primer dan data sekunder dengan menggunakan kuesioner sebagai instrumen pengumpul data. Desain penelitian metode cross sectional analisis data dilakukan dengan menggunakan SPSS versi 19 dan sistem PLS-Smart. Hasill penelitian menunjukkan adanya pengaruh langsung dan tidak langsung disiplin kerja, kompetensi dan motivasi terhadap produktivitas pegawai sebesar 75,71% sedangkan 24,29% yang mempengaruhi produktivitas pegawai administrasi dan keuangan di RS MH Thamrin Internasional Salemba. Disarankan penelitian selanjutnya memperluas objek penelitian dan menambah variabel lain yang secara teori memiliki pengaruh terhadap produktivitas pegawai.  Kata kunci : Disiplin Kerja; Kompetensi; Motivasi ; Produktivitas Abstract Patient visits in September-October 2012 have not reached the target desired by the owner of RS.MH.Thamrin International Salemba, namely 300 patients who seek treatment every month while what is achieved from the marketing division is only 145 patients who seek treatment in October 2012 there are 5 employees who resigned from admission to medical records RS.MH.Thamrin International Salemba. The purpose of this study to determine the effect of direct and indirect labor discipline, competence and motivation on employee productivity and financial administration RS International MH. Thamrin Internasional Salemba. The research was done at the hospital with the sample Salemba International MH Thamrin 64 people using primary data and secondary data using a questionnaire as a data collection instrument. The study design is cross sectional method of data analysis performed using SPSS version 19 and PLS-Smart system. Results showed that the influence of labor the influence of labor discipline, competence and motivation on employee productivity by 75.71% and 24.29% explained komponen that affect employee productivity and financial administration in RS. MH. Thamrin Internasional 2012. 

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