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SRIWIJAYA JOURNAL OF MEDICINE
Published by Universitas Sriwijaya
ISSN : -     EISSN : 26223589     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health
Sriwijaya Journal of Medicine (SJM) is a scientific journal managed by Faculty of Medicine Universitas Sriwijaya, Indonesia. It publishes original research articles and reviews in Biomedical Sciences, Medicine (Neurology, Cardiovascular, Respiratory, Gastrointestinal, Urogenital, Endocrine and Metabolism, Integument, Mental Health, Obstetry and Gynecology, Ophtalmology, ENT, Musculosceletal) and Public Health Medicine. Sriwijaya Journal of Medicine (SMJ) published three times a year (January, April, October).
Arjuna Subject : Kedokteran - Anatomi
Articles 315 Documents
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CRISPR-Cas9 Potential in Eradicating HIV Latent Reservoir as The Up-to-date Therapy For HIV-1 Salim, Jesica Putri; Anggraini, Friska; Safa Nabila Putri; Maritska, Ziske
Sriwijaya Journal of Medicine Vol. 4 No. 1 (2021): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v4i1.206

Abstract

According to the Ministry of Health in Indonesia, in 2018, there are about 640 thousand cases of people with HIV within the death rate of 38 thousand people. This number grows annually, in fact, according to WHO, there are approximately 38 million people who are diagnosed with HIV in the world in 2019. Thus, HIV-AIDS is a dangerous health problem and needs to be taken care of as soon as possible. HIV (Human Immunodeficiency Virus) is a retrovirus that got its name from the infecting immune cells in the human body. There are two types of HIV, named HIV-1 and HIV-2. Both have the same basic gene arrangement, transmission process, intracellular replication lane, and both cause AIDS. The differences between them are the HIV-1 spreads globally, while HIV-2 locally happens in West Africa. Currently, ART (Antiretroviral Therapy) is the most commonly used method of treatment for HIV-1. Treatment for HIV-1 with ART is effective in controlling HIV-1 virus replication but has not been able to completely eradicate the latent viral reservoir. In the past few years, it is known that there is a CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat) method that can modify genes (DNA) in the body of an organism. However, apart from its potential in handling HIV-1, there are still obstacles in the mechanism.
The Effect of Hydrotherapy on Pain Intensity and Functional Ability in Lumbar Disk Herniation (LDH) Patients that Undergo Non-operative Procedure Pre-experimental Study at Medical Rehabilitation Installation of RSUP dr. Mohammad Hoesin Palembang Rahmadhani, Theresa; Nyimas Fatimah; Eka Febri Zulissetiana
Sriwijaya Journal of Medicine Vol. 3 No. 3 (2020): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v3i3.214

Abstract

The effect of hydrotherapy on pain intensity and functional ability in lumbar disk herniation (LDH) patients thatundergo non-operative procedure; pre-experimental study at medical rehabilitation installation of RSUPdr. Mohammad Hoesin Palembang. Lumbar disk herniation (LDH) is the most common disease that becaused low backpain and functional disability. Some studies mentioned that hydrotherapy is an effective treatment for low back pain.Therefore, this study was conducted to determine the effect of hydrotherapy on reducing pain intensity and improvingfunctional ability in LDH patients. This study was a pre-experimental study with one group pretest-posttest design. Datawas collected by direct interviews to the patients using visual analogue scale (VAS) to measure pain intensity andModified Oswestry Low Back Pain Disability Questionnaire to assess functional ability before and after underwenthydrotherapy once a week for 4 weeks. The data then undergo Shapiro-Wilk normality test and continue with Paired t-Test or Wilcoxon test. From 30 subjects, it was found that there are effects of hydrotherapy on reducing pain intensity(p<0,001) and improving functional ability (p<0,001) in LDH patients that undergo non-operative procedure at theMedical Rehabilitation Installation of RSUP Dr. Mohammad Hoesin Palembang. There are effects of hydrotherapy onpain intensity and functional ability in LDH patients that undergo non-operative procedure.
Optimization of Test Management in Maluku Health Analyst Department M Natsir, Ramdhani
Sriwijaya Journal of Medicine Vol. 3 No. 3 (2020): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v3i3.215

Abstract

Introduction. Exam management is crucial in the implementation of evaluation in educational institutions. This isbecause the test implementation process is one of the determinants of the quality of an institution. This study aims toassess the optimization of examination management in the health analyst department of the Health Polytechnic of theMinistry of Health in Maluku. Methods. This study used a descriptive research design. This research was conducted inthe health analyst department of the Maluku Health Polytechnic Ministry of Health in July - August 2019. The samplein this study were all employees and students in the Maluku Health Poltekkes Department of Health analyst with thesampling technique using total sampling. A Likert scale questionnaire was used as an instrument in the study. Results.There are respondents with more job distribution, namely 45 students (80.4%). Respondents who rated theapplication and website development category as very satisfied were 30 respondents (53.5%), and satisfied were 26respondents (46.5%). Respondents who assessed the optimal management of the examination category were verysatisfied with 38 respondents (67.8%), and satisfied with 18 respondents (32.2%). Conclusion. There is no relationshipbetween the implementation of the SOP for exam management with optimal exam management, and there is arelationship between making applications and websites with optimal exam management.
Correlation of Radiological Severity of Genu Osteoarthritis (Kellgren and Lawrence) with Functional Disabilities (Womac Score) Novita, Mitha; Nyimas Fatimah
Sriwijaya Journal of Medicine Vol. 3 No. 3 (2020): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v3i3.216

Abstract

Background: Osteoarthritis (OA) is a degenerative disease that most often causes functional disabilities. Thecomplaints that most often cause functional disabilities in people with OA are pain and stiffness. The severity of OAcan be seen radiologically. The aim of this study was to assess the correlation of radiological severity of OA (Kellgrenand Lawrence) with functional disabilities (WOMAC score). Method: This type of research is an analytic observationalstudy with a cross sectional design. The population who became the respondents of this study were patients sufferingfrom knee osteoarthritis at the Medical Rehabilitation Installation of Dr. Mohammad Hoesin Hospital, Palembang inNovember 2018 who met the inclusion criteria. Samples were taken by consecutive sampling technique. Thefunctional ability of the patient will be assessed using the WOMAC score and the severity of OA radiologicallyinterpreted based on the Kellgren and Lawrence criteria. Result: Statistical test used Somer's correlation test. From 32respondents' data, it was found that there was no significant correlation between the radiological severity of OA andfunctional disability (p = 0.097). Conclusion: There is no significant correlation between radiological severity of OA(Kellgren and Lawrence) with functional disabilities (WOMAC score).
The Effect of Hydrotherapy in Low Back Pain Patients Walean, Monica Karina; Nyimas Fatimah
Sriwijaya Journal of Medicine Vol. 3 No. 3 (2020): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v3i3.217

Abstract

Background: Low back pain (NPB) is the first disease that causes disabilities at all ages, and its incidence increases withage. A number of previous studies have reported that hydrotherapy has an effect on improving low back pain andincreasing flexibility.Therefore, this study aims to determine the effect of hydrotherapy on pain intensity andlumbosacral flexibility in low back pain patients at dr. Mohammad Hoesin Palembang. Methods: This study is a pre-experimental study with a one group pretest-posttest design with a sample size of 35 NPB patients. Inclusion criteriawere NPB patients who did not undergo operative action, had no contraindications to undergo hydrotherapy, andwere > 29 years old. The exclusion criteria were patients with communication disabilities and a history of low backpain due to infection, tumor and metastases. Subjects dropped out of the study if they underwent hydrotherapy lessthan three times or withdrew. Pain intensity and lumbosacral flexibility data were obtained before and after thesubject underwent hydrotherapy once a week for one month. Results: There was a decrease in pain intensity from5.57 to 4.00 (p <0.001) and an increase in lumbosacral flexibility from 48.10 to 48.73 (p = 0.014) in low back painpatients undergoing hydrotherapy. Conclusion: There is an effect of hydrotherapy on reducing pain intensity andincreasing lumbosacral flexibility in low back pain patients undergoing hydrotherapy at the Medical RehabilitationInstallation Dr. Mohammad Hoesin Palembang
The Correlation of the Limitations of Movement of the Shoulder Joint with the Functional Ability of Frozen Shoulder Patients at the Medical Rehabilitation Institute Dr. Mohammad Hoesin Palembang Sintia, Ine; Nyimas Fatimah
Sriwijaya Journal of Medicine Vol. 3 No. 3 (2020): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v3i3.218

Abstract

Background: Frozen shoulder is a condition of the shoulder joint that experiences inflammation, pain, adhesions, atrophyand shortening of the joint capsule resulting in limited motion. In frozen shoulder patients, the limited range of motion ofthe shoulder joint can affect and reduce functional ability. This study aims to analyze the correlation between the limitedarea of motion of the shoulder joint with the functional ability of frozen shoulder patients at the Medical RehabilitationInstallation Dr. Mohammad Hoesin Palembang. Methods: This study was an observational analytic study, correlationtest, with a cross sectional design. There were 29 frozen shoulder patients who met the inclusion criteria in the MedicalRehabilitation Installation Dr. Mohammad Hoesin Palembang in November 2018 was taken as a sample using consecutivesampling techniques. Functional ability was assessed using the quickDASH questionnaire and the area of motion wasmeasured using a goniometer, then analyzed. Results: The results of the correlation test showed significant resultsbetween functional abilities and the area of motion of the shoulder joints. Active flexion (p = 0.000; r = -0.669), activeextension (p = 0.004; r = -0.520), active abduction (p = 0.000; r = -0.663), active adduction (p = 0.022; r = -0.423 ), passiveflexion (p = 0.001; r = -0.589), passive extension (p = 0.002; r = -0.543), passive abduction (p = 0.000; r = -0.676), passiveadduction (p = 0.038; r = -0.388). Conclusion: There is a significant correlation between limited joint motion andfunctional ability in frozen shoulder patients at the Medical Rehabilitation Installation of Dr. Mohammad HoesinPalembang
Quantitative Antibiotic Use Profile in Typhoid Kurniawati, Hidayatul; Marianti
Sriwijaya Journal of Medicine Vol. 3 No. 3 (2020): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v3i3.219

Abstract

Background. Typhoid fever is a common health problem in developing countries. Antibiotics are used to treat typhoidfever which is caused by a bacterial infection. Selection and use of appropriate and rational antibiotic therapy candetermine a success in treatment to avoid bacterial resistance and minimize drug side effects. This study aims todetermine the rationality of the use of antibiotics in adult patients diagnosed with typhoid fever in the InpatientInstallation of X Hospital in Yogyakarta. Method. Non-experimental research with descriptive observational researchdesign and retrospective data collection. The sample of this study was inpatients with a diagnosis of typhoid fever andwas recorded at the X Hospital Medical Records Installation in Yogyakarta for the period January 2016 - December2017 which was included in the inclusion criteria. Result. Data taken came from 75 medical records that were includedin the inclusion criteria. Patients were dominated by female patients as many as 64% and the adult age range was 18-30 years. The single most widely used antibiotic was levofloxacin in 27 cases (36%). The use of antibiotics with theright indication was 75 patients (100%), the right type was 75 patients (100%), the exact duration of administrationwas 64 patients (85.33%), the right dose was 73 patients (97.33%), the right interval was 73 patients (97.33%) and theright route of administration were 75 patients (100%). Conclusion. The rationality of using antibiotics is good withaccuracy> 75%.
The Effectiveness of Karamunting Leaf’s Fraction (Rhodomyrtus tomentosa (Aiton) Hassk) as Antimicrobials in Carbapenemase Resistant Klebsiella pneumonia Sabrina, Tia; Kamaluddin, MT; Theodorus, Theodorus; Salni, Salni
Sriwijaya Journal of Medicine Vol. 4 No. 1 (2021): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v4i1.225

Abstract

In the world, the incidence of nosocomial infections in hospitals had increased. There had been an increase in the incidence of infections caused by Enterobacteriaceae, one of them is Klebsiella pneumonia, which resistant to carbapenem in the worldwide. The consequences of increased rates of resistance to many drugs pose a high need for the discovery of new types of antibiotic drugs. Rhodomyrtus tomentosa (aiton) hassk has an antibacterial effect that has long been used by Indonesians as a traditional drug. This study aims to find out the effectiveness of karamunting leaf fraction as an antimicrobial in carbapenemase resistant K.pneumonia bacteria and to find out the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the active compound of karamunting leaves as antimicrobial in Carbapenemase resistant Klebsiella pneumonia (CRKP) bacterial isolates. This research was an experimental laboratory research in vitro that exploratory analytical. The results of the study obtained the value of MIC ethyl acetate fraction started at a concentration of 125 μg/ml and n-hexan fraction at a concentration of 4000 μg/ml. MBC value was 125 μg/ml for ethyl acetat fraction and n-hexan fraction of karamunting leaves was 8000 μg/ml. From the bacterial activity test obtained at a concentration 32000 μg/ml of n-hexan fraction, the average diameter of the inhibitory zone 7.80 ± 1.30 mm and ethyl acetate fraction at a concentration of 4000 μg/ml can inhibit the growth of CRKP bacteria with an average of inhibition zone diameter was 9.40 ± 1.67 mm. From the results of the analysis using the Independent T Test and mann whitney test obtained a probability value between all groups with positive control was <0.05. It can be concluded that the ethyl fraction of acetate and n-hexan leaves of karamunting leaves contains active compounds that can interfere with the integrity of CRKP bacterial cell walls or membranes so that the bacteria can die.
The Relationship Between Activity Daily Living Level And Quality Of Life Of Geriatric Patients In RSUP Dr. Mohammad Hoesin Palembang Linata, Angela Maria; Jalalin
Sriwijaya Journal of Medicine Vol. 3 No. 3 (2020): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v3i3.226

Abstract

Background The quality of life of the elderly is influenced by several factors such as physical health, psychological health,and good social relationships. Physical health is related to daily living activities that a person does in his daily lifeincluding ambulation, eating, dressing, bathing, brushing teeth and making up. At old age, a person will experience adecrease in physical condition which will affect the value of fulfilling one's daily living activities. This study aims toanalyze the relationship between the level of independence of daily living activities and the level of quality of life ofgeriatric patients. Methods: This study was an observational analytic study with a cross sectional design. The sampleswere geriatric patients in Dr. Mohammad Hoesin Palembang in September-October 2019. The sample of this study was55 respondents. Results: From 55 Geriatric patients in Dr. Mohammad Hoesin Palembang found 60% male respondentsand 40% female respondents, the 60-74 years age group as much as 74.5%, the 75-90 year age group as much as 25.5%,the 50-60 year age group as much as 26%. Chi-square test results showed a significant relationship between the level ofActivity Daily Living and the level of quality of life of geriatric patients (p value = 0.000). The results of the odds ratio ingeriatric patients state that the probability of improving the quality of life is 27.7 times greater in patients who have anindependent daily living activity level than in patients who have a total dependent daily living activity level. In theanalysis, it was also found that the level of daily living activity of geriatric patients is a protective factor for the quality oflife of geriatric patients. (95% CI = 0.006-0.206). Conclusion: There is a significant relationship between the level of dailyliving activity and the quality of life of geriatric patients in , dr. Mohammad Hoesin Palembang.
The Incidence of Knee Pain Complaints in Pedicab Riders in the Kemuning District, Palembang Oktari, Nendy; Jalalin
Sriwijaya Journal of Medicine Vol. 3 No. 3 (2020): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v3i3.227

Abstract

Background: Knee pain is a major source of disability, and the most frequently complained of disease in people aged 50years and over, this complaint is often associated with osteoarthritis. Complaints of knee pain in OA patients are stronglyassociated with decreased stability of the knee joint. As the main stabilizer in the knee joint, extensor muscle strengthplays a major role in the pain complaints that occur, so that one of the recommended physiotherapy measures for kneeosteoarthritis patients in reducing pain complaints is to exercise the knee extensor muscle strengthening in the form ofpedaling a bicycle. The pedaling movement is a work activity carried out by pedicab drivers. Therefore, this study wasconducted to determine the incidence of knee pain complaints in pedicab riders in the District of Kemuning, Palembang.Method: This type of research is descriptive with cross sectional study design. The study population was pedicab driverswho operated in the Kemuning District of Palembang. Primary data were collected by conducting interviews todetermine whether there were complaints of pain in the knee and assessed by the KOOS Score and Numeric Rating Scale(NRS), as well as measurements of body weight and height. Results: The results showed that 8 pedicab drivers (17.8%)complained of knee pain and 37 pedicab drivers (82.2%) did not complain of pain in their knees. Conclusion: Theincidence of knee pain complaints among pedicab drivers in the Kemuning sub-district of Palembang is lower than that ofpedicab drivers who do not complain of pain in their knees.

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