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INDONESIA
ISM (Intisari Sains Medis) : Jurnal Kedokteran
Published by Universitas Udayana
ISSN : 25033638     EISSN : -     DOI : -
Core Subject : Health, Science,
Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.
Arjuna Subject : -
Articles 1,063 Documents
Gambaran pemeriksaan IgM anti-Salmonella thypi 09 pada penderita demam dan gangguan pencernaan, dengan atau tanpa gangguan kesadaran di Puskesmas Denpasar Timur I IGA Ayu Ratih Pradnyadewi; Ni Nyoman Mahartini; I Wayan Putu Sutirtayasa
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (242.014 KB) | DOI: 10.15562/ism.v10i3.422

Abstract

Latar Belakang: Demam tifoid merupakan penyakit endemik Indonesia, yang disebabkan oleh infeksi dari bakteri Salmonella typhi. Bakteri ini dapat ditularkan melalui makanan dan juga minuman yang terkontaminasi bakteri tersebut, bisa juga akibat dari terkontaminasi dari tinja maupun urin dari orang yang telah terinfeksi bakteri tersebut. Penegakan untuk diagnosis demam tifoid saat ini dapat dilakukan secara klinis maupun dengan cara pemeriksaan laboratorium. Salah satunya ialah uji serologis yang dapat digunakan dalam demam tifoid meliputi tes Tubex.Metode: Penelitian ini merupakan penelitian deskriptif dengan pendekatan cross-sectional. Data dalam penelitian ini berasal dari sumber data primer berupa pengambilan serum pasien di Puskesmas Denpasar Timur I sejumlah 33 sampel.Hasil: Pasien yang berobat ke Puskesmas Denpasar Timur I didapatkan kelompok yang paling banyak ialah perempuan 81,9% sedangkan laki-laki 18,1%. Sebanyak 100% datang dengan keluhan demam, sebanyak 63,7% datang dengan keluhan mual dan muntah 9,0%.Simpulan: Hasil IgM anti-Salmonella thypi 09 positif sebanyak 9,1% dan IgM anti-Salmonella thypi 09 negatif sebanyak 90,9%.Introduction: Typhoid fever is an endemic disease in Indonesia, which is caused by an infection of the bacterium Salmonella typhi. These bacteria can be transmitted through food and beverages contaminated with these bacteria, can also be caused by contamination of feces and urine from people who have been infected with these bacteria. Enforcement for the diagnosis of typhoid fever can now be done clinically or by laboratory examination. One of them is the serological test that can be used in typhoid fever including the Tubex test.Method: This research is a descriptive study with a cross-sectional approach. The data in this study came from primary data sources in the form of taking serum of patients in the East Denpasar Health Center I with 33 samples.Result: Patients who went to the East Denpasar Public Health Center I, found the most group was women 81.9% while men 18.1%. As many as 100% came with complaints of fever, 63.7% came with complaints of nausea and vomiting were 9.0%.Conclusion: The positive results of anti-Salmonella thypi 09 were 9.1% and negative IgM anti-Salmonella thypi 09 as much as 90.9%.
Hubungan antara perubahan iklim dengan jumlah kasus demam dengue (DD) di Denpasar, Bali tahun 2010-2015 I Gusti Agung Bagus Arya Wiradarma; I Ketut Agus Somia
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (777.64 KB) | DOI: 10.15562/ism.v10i3.423

Abstract

Background: Dengue is one of tropical infectious disease that can give a serious public health problem in Denpasar. Several factors have been associated with the high prevalence of dengue fever; one of them is climate changes. This study aims to determine the relations between climate change and a number of dengue cases in Denpasar.Methods: The climate change and a number of dengue cases data take place in Denpasar from the year 2010-2015 using observational study. The Spearman correlation test was used to know the relation between climate change ( maximum and minimum temperature, rainfall, humidity, light duration, and wind velocity ) and a number of dengue cases. Data were analyzed using SPSS version 20 software for windows.Results: The highest prevalence of Dengue Fever infection was in 4,431 (38.16%) cases in 2010, followed by 1,837 (15,82%) cases in 2014, 1,766 (15.22%) cases in 2013, 1,576 (13.57%) cases in 2015, 1,009 (8.69%) cases in 2012, and 992 (8.54%) cases in 2011. Based on climate variables, rainfall has a weak significant relation affecting the number of dengue cases compared with others (r=0.247; p=0.036).Conclusion: Rainfall was the only climates variables significantly related to the high prevalence of dengue fever in Denpasar, Bali since 2010-2015. So, further efforts need to be done to prevent dengue cases on rainy season.
Self-esteem formation among people who are in rehabilitation for drug abuse in Bangli Mental Health Hospital, Bali, Indonesia Mde Dewi Sariyani; Ni Komang Ekawati; Dyah Pradnyaparamita Duarsa; Kadek Sri Ariyanti
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (787.616 KB) | DOI: 10.15562/ism.v10i3.424

Abstract

Background: Self-esteem formation is an essential aspect for people who use drugs to support the success of a rehabilitation program, and to prevent ongoing relapse. However, self-esteem formation is not a priority in the rehabilitation program. It also tends to ignore the drug abuse status and psychological states of its clients. This study aimed to explore self-esteem formation among people who are in rehabilitation for drug abuse at the Bangli Mental Health Hospital. Findings from this study provide insights to the hospital on the importance of self-esteem formation through a rehabilitation program.Metode: A qualitative study was conducted in the Bangli Mental Health Hospital. We recruited a total of ten informants purposively who are in a rehabilitation program for at least two weeks for drug abuse at the Darmawangsa Ward Bangli Mental Health Hospital. Data were collected through in-depth interviews. Data were analyzed inductively and were presented using a narrative approach.Results: Our in-depth interviews found that self-esteem formation among people who are in rehabilitation for drug abuse depends on various factors such as family support, peer support, life experience, skills and traits, spirituality, policies, parenting history, physical and social environments.Conclusion: Self-esteem formation is determined by various factors and the drug abuse status of informants. We hope that the Bangli Mental Health Hospital can provide rehabilitation services tailored for every drug abuse status during their recovery time at the rehabilitation center.
Uji efektivitas ekstrak etanol kulit buah naga merah (Hylocereus polyrhizus) terhadap Staphylococcus aureus ATCC 25923 secara in vitro Anak Agung Bintang Astridwiyanti; Agung Nova Mahendra; Ni Wayan Sucindra Dewi
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (599.437 KB) | DOI: 10.15562/ism.v10i3.425

Abstract

Introduction: Infectious diseases are still one of the main causes of high morbidity and mortality in tropical Indonesia. One of the causes of this disease is the staphylococcus aureus bacteria. Red dragon fruit peel contains potentially antibacterial compounds such as flavonoid, alkaloid, saponin, tannin dan terpenoid. The purpose of this study is to determine the antibacterial activity of ethanolic extract of red dragon fruit peel against staphylococcus aureus ATCC 25923.Method: The method used is true experimental post test only control group design. The activity of ethanol extract of red dragon fruit skin was tested in various concentrations (25%, 50%, 75%, and 100%) against staphylococcus aureus ATCC 25923 by measuring the inhibition zone diameter and minimum inhibitory concentration (MIC).Result: The results of this study show that red dragon fruit peel ethanolic extract has antibacterial activity against staphylococcus aureus ATCC 25923 ith the average diameter of inhibition zone ranging from 8.25 mm – 12.5 mm. The MIC is obtained at concentration of 25%. Kruskal-Wallis test found a significant comparison with a value of p = 0,000 (p value <0.05). Mann-Whitney test showed that there were significant differences between each concentration, except the concentration of 50% did not have a significant difference with a concentration of 75%.Conclusion: The minimum inhibitory concentration (MIC) is produced by extract at a concentration of 25% and the best inhibitory zone produced by 100% concentration of red dragon peel ethanol extract.
Hubungan kadar serum gamma-glutamyl transferase dengan profil lipid pada Diabetes Melitus-Tipe 2 (DM-2) terkontrol dan tidak terkontrol di Rumah Sakit Umum Pusat Haji, Adam Malik Medan, Indonesia Furiyani Furiyani; Santi Syafril; Burhanuddin Nst
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.652 KB) | DOI: 10.15562/ism.v10i3.426

Abstract

Background: Diabetes mellitus is a group of metabolic diseases with characteristics of hyperglycemia that occur due to impaired insulin secretion, insulin work, or both whereas also impaired lipid peroxidation caused by oxidative stress. Gamma-glutamyl transferase (GGT) is an enzyme on the surface of the cell membrane that is responsible for the catabolism of glutathione which acts as a marker of oxidative stress. This study aims to determine the relationship of serum GGT levels with lipid profiles in controlled and uncontrolled type 2 DM.Method: A cross-sectional study was conducted at H. Adam Malik General Hospital Medan from September - November 2018 among 60 patients with type 2 DM grouped according to HbA1c <7% controlled and HbA1C > 7% uncontrolled. GGT levels and lipid profiles examined using enzymatic calorimetry and HbA1c with Immunoturbidimetry method. The relationship of serum GGT levels with lipid profiles in controlled DM-2 was tested using the Pearson correlation test whereas controlled DM-2 correlation test using the Spearman's correlation test using SPSS version 21 for Windows.Results: Most of respondents were males with HbA1C levels <7% (53.3%) and HbA1C ≥ 7% (60.0%). There was no difference in the mean age and serum GGT levels between uncontrolled DM-2 or controlled DM-2 group (P = 0.260 and P = 0.520, respectively). There was no association between serum GGT levels and lipid profiles in the controlled type 2 DM group and uncontrolled type 2 DM. (r=P> 0.05).Conclusion: There is no significant relationship between serum GGT levels and lipid profiles in controlled and uncontrolled type 2 DM groups.
Hubungan antara TIL (Tumor Infiltrating Lymphocyte) dan MAI (Mitotic Activity Index) dengan kejadian metastase kelenjar getah bening (KGB) aksila pada operable breast cancer di RSUP Sanglah, Denpasar. I Gede Aditya Krishna Santhi; I Nengah Wiadnyana Steven Christian; I Gede Raka Widiana
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (382.19 KB) | DOI: 10.15562/ism.v10i2.427

Abstract

Latar belakang: Kanker payudara merupakan penyakit yang menduduki urutan ketiga di Eropa dan United State sebagai jenis kanker yang menyebabkan kematian. Studi dua dekade terakhir mengungkapkan bahwa Tumor microenvironment (TME)juga merupakan penentu penting perilaku tumor.Tumor padat umumnya terdiri dari berbagai sel kekebalan tubuh, termasuk limfosit T dan B, sel NK, makrofag, dan neutrofil. Imunitas adaptif dan imunosupresi selalu menunjukkan tingkat ekspresi yang berbeda pada tumor, dan banyak gen kekebalan terkait dengan inflamasi. Interaksi antara sel imunitas menentukan induksi atau penghambatan perkembangan tumor, angiogenesis, dan metastasis. Sistem imunitas mempengaruhi surveillance pada pasien kanker. Proliferasi telah dikenali sebagai “hallmark” dari kanker dan merupakan faktor prognostik kanker. Evaluasi dari derajat proliferasi sel dalam jaringan tumor digunakan untuk menilai progresifitas tumor. Penilaian indeks mitosis telah digunakan sebagai “gold standard” dalam menilai agresivitas tumor. Maka dari itu, tujuan penelitian ini adalah untuk mengetahui hubungan respon imun pada tumor dalam hal ini sel Lymphocyte dan aktifitas pembelahan sel tumor dengan kejadian penyebaran kanker ke KGB aksila pada operable breast cancer di RSUP Sanglah Denpasar. Metoda:Lima puluh tiga sampel pasien kanker payudara post MRM (Modified Radical Mastectomy) yang berobat di RSUP Sanglah yang mempunyai catatan medis (data klinis, histopatologis), sampel dipilih secara eligible sampling pada rekam medis pasien di Bagian/ SMF Bedah Onkologi Fakultas Kedokteran Universitas Udayana RSUP Sanglah dari tahun 2016 sampai dengan 2018. Penelitian ini merupakan “Cross Sectional Analitik" hubungan antara TIL dan MAI dengan kejadian metastase KGB aksila pada pasien operable breast cancer     secara univariant, bivariat dan multivariant dengan menggunakan perangkat lunak SPSS 20 for windows. Hasil: menunjukkan analisa dengan uji Chi-square didapatkan pasien dengan low TIL (P= 0,627), intermediate TIL (P= 0,339) dan pasien dengan MAI  ≥ 25 /10 lp (P= 0,531), MAI 13-24 /10 lp (P= 0,531) tidak dijumpai adanya hubungan bermakna dengan kejadian metastase KGB aksila karena tidak signifikan secara statistika.  Simpulan:tidak dijumpai adanya hubungan bermakna, low dan intermediate TIL memiliki kecenderungan metastase KGB aksila pada Operable Breast Cancer lebih tinggi, dan dijumpai pula adanya kecenderungan makin tinggi MAI, semakin tinggi resiko metastase KGB aksila pada operable breast cancer di RSUP Sanglah Denpasar.Hubungan antara TIL (Tumor Infiltrating Lymphocyte) dan MAI (Mitotic Activity Index) dengan kejadian metastase kelenjar getah bening (KGB) aksila pada operable breast cancer di RSUP Sanglah, Denpasar.
Gambaran kepuasan pasien rawat jalan terhadap pelayanan kesehatan di UPT Kesmas Payangan, Gianyar, Bali Ni Kadek Novi Antari
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (281.355 KB) | DOI: 10.15562/ism.v10i3.428

Abstract

Background: Health service is any efforts held by personal or together in an organization to maintain and increasing health as well as patient’s satisfaction. This study aims to know the outpatient patients’ satisfaction representation toward health service in UPT Kesmas Payangan.Methods: A cross-sectional descriptive study was conducted among 85 outpatient at UPT Kesmas Payangan. Sample technique used in this study was convenience sampling method. Samples are outpatient patients who were visiting UPT Kesmas Payangan and assesses using valid and reliable questionnaire regarding patient’s satisfaction based on 5 dimensions (tangible, reliability, responsiveness, assurance, empathy). Data were analyzed using SPSS version 20 for Windows.Results: Most of outpatient are satisfied at UPT Kesmas Payangan (88.2%). Based on satisfaction dimension, our study found that more patients are satisfied in reliability (82.3%), responsiveness (94.1%), assurance (92,9%), tangibles (84.7%), and empathy (88,2%). In addition, female patients are more satisfied (91,3%) than males (84,6%), following by lower level of education is more satisfied (95,2%) as well as in jobless group (100%) compared with others. According to the method of payment, group that using out of pocket method is more satisfied (90%) than using BPJS health insurance (88%).Conclusion: Most of outpatients at UPT Kesmas Payangan are satisfied with health services provided particularly in responsiveness dimension. Out of pocket as method of payment is also tend to given higher satisfaction than BPJS health insurance.
Characteristic overview of aplastic anemia at Sanglah Hospital, Bali-Indonesia in 2017-2018 Komang Agus Widhy Utama Putra; A.A Ngurah Subawa; A.A Wiradewi Lestari
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (495.549 KB) | DOI: 10.15562/ism.v10i3.429

Abstract

Background: Aplastic anemia is a rare disease of anemia which characterized by pancytopenia due to spinal cord hypoplasia. This can occur in people of any age, race, and gender with different degree of severity, with incidence rate is two until three times higher in Asia than the West. This study aims to determine the characteristic of aplastic anemia based on age, gender, laboratory examination, and severity in Sanglah Hospital.Methods: This research is a cross sectional descriptive study with sources of data were medical records of aplastic anemia patients at Sanglah Hospital in the last 2 years, 2017-2018. Distribution of research variables is gender, age, laboratory examination, and severity.Results:The result showed that 11 data were 6 (55%) male and 5 female (45%), with the mean age was 48 ± 14 years. The highest incidence occurred in the age range of 26-60 years old with 7 patients (64%). In this study the average hemoglobin level obtained was 9.94 ± 1.46 g/dL with range between 6.65 to 12.49 g/dL. The average number of leukocytes was 11.91 ± 24.52 x 109 L with range of leukocytes is 1.99-84.58 x 109/L. The average number of absolute Neutrophils and percent was 1.53 ± 1.52 x 109/L and 25.99 ± 25.79% with range between 0.06 – 4.53 x 109/L and 2.3 - 70.83%. The average platelet count was 24.77 ± 11.35 x 109/L with range between 4.25 – 42.58 x 109/L. The highest cases were nonsevere aplastic anemia (NSAA) with 7 people (64%).Conclusion: The value of laboratory parameters for complete blood examination (leukocytes, platelets, hemoglobin, and neutrophils) in patients with aplastic anemia at Sanglah General Hospital is still very low, so it is a challenge for clinicians to carry out treatment of aplastic anemia and management related complications.
Perilaku hand hygiene tenaga kesehatan di RSUP Sanglah tahun 2018 Made Dwi Andhika Yogiswara; Ni Luh Putu Ariastuti; Putu Aryani
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.162 KB) | DOI: 10.15562/ism.v10i3.430

Abstract

Background: Low hand hygiene behavior is a very detrimental and a cause of health care associated infection and is a problem faced by patients and the medical profession at this time. The purpose of this study was to find out the distribution of hand hygiene behavior among healthcare professionals in Sanglah General Hospital Denpasar.Method: This study was conducted using a descriptive method with a cross-sectional study design carried out in the polyclinic and inpatients ward at Sanglah General Hospital in September to November 2018.Results: From the 96 study samples, 82.3% had good compliance with hand hygiene standards and 68.7% had a positive perception of hand hygiene. Women are more obedient than men towards the implementation of hand hygiene and doctors is the lowest profession to have a level of adherence to hand hygiene.Conclusion: Perception and compliance with hand hygiene in medical personnel at Sanglah General Hospital Denpasar has been very good, but it still needs to be improved so that all medical personnel perform hand hygiene procedures as a routine practice for the sake of infection prevention and control.
Culture results on chest tube thoracostomy water-sealed drainage in patients with pneumothorax at Sanglah General Hospital, Bali-Indonesia Putu Bagus Anggaraditya; Arland Chandra
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (255.637 KB) | DOI: 10.15562/ism.v10i1.431

Abstract

Introduction: Thoracic trauma is one type of trauma with a high incidence that causes morbidity and mortality after head trauma and extremity. The act of installing a thoracostomy has become one of the standard management of thoracic injury. Infection is a complication that can occur during treatment. This study aimed to provide an overview of the results of thoracostomy tube water-sealed drainage (WSD) culture in pneumothorax patients at Sanglah Hospital.Method: The study design used a cross sectional descriptive method. The subjects of the study were blunt thoracic trauma patients with pneumothorax who came to the emergency department of Sanglah Hospital to indicate the installation of a thoracostomy hose during the period January to December 2018.Results: From 40 study samples there were 32 subjects with positive culture results, then from all subjects with positive culture results found 10 people (25%) with culture results of staphylococcal aureus bacteria, based on rib fractures more samples with rib fractures less than two bones ( 62.5%), based on the duration of WSD installation there were more samples with the duration of WSD installation more than 7 days (75%).Conclusion: The high positive culture results which are dominated by pyogenic skin bacteria, namely Stapylokokus aureus is a challenge for surgeons in managing the complications of tube thoracostomy (TT) installation in patients with pneumothorax.

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