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INDONESIA
YARSI Medical Journal
Published by Universitas Yarsi
ISSN : 08541159     EISSN : 24609382     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 232 Documents
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POTENSI KURKUMIN SEBAGAI BAHAN ANTI FERTILITAS Purwaningsih, MS, PA, Endang
Jurnal Kedokteran YARSI Vol 24, No 3 (2016): SEPTEMBER - DESEMBER 2016
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jky.v24i3.267

Abstract

Kunyit (Curcuma longa, Linn) merupakan salah satu herbal yang sering digunakan sebagai bumbu, pengawet maupun pewarna makanan. Senyawa utama ekstrak kunyit adalah kurkumin.yang memberikan warna kuning yang khas. Telah banyak dilakukan penelitian yang berkaitan dengan efek biologik dan aksi farmakologiknya, seperti antiinflamasi, antikanker, antioksidan  dan antifertilitas.Dalam makalah ini akan dipaparkan mengenai efek kurkumin terhadap sistem reproduksi, khususnya sebagai antiferlitas. Pada sistem reproduksi pria/jantan kurkumin menghambat kualitas spema seperti motilitas, viabilitas sperma, kapasitasi, reaksi akrosom, dan meningkatkan morfologi sperma abnormal. Kurkumin juga dapat melindungi dampak negatif alkohol, potasium dikromat, kadmium, metronidazol terhadap testis, kualitas sperma dan produksi hormon testosteron. Pada sistem reproduksi wanita/betina kurkumin dapat menghambat ovulasi, implantasi, dan produksi hormon FSH, LH, estrogen maupun progesteron. Selain itu kurkumin dapat memblok siklus estrus dan menimbulkan perubahan biokimiawi pada cairan uterus. Dapat disimpulkan bahwa kurkumin memiliki potensi dalam pengendalian kesuburan khususnya sebagai bahan antifertilitas baik pria maupunwanita. Efek antifertilitas kurkumin bersifat reversibel. 
UJI EFIKASI INSEKTISIDA BERBAHAN AKTIF ALPHACYPERMETHRIN TERHADAP LALAT RUMAH MUSCA DOMESTICA DENGAN PENGASAPAN Suwasono, Hadi; Boesri, Hasan; Priyanto, Heru; Suwaryono, Tri
Jurnal Kedokteran YARSI Vol 15, No 1 (2007): JANUARI - APRIL 2007
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (113.255 KB) | DOI: 10.33476/jky.v15i1.1007

Abstract

Although being of less importance to the incidence of the vector-borne disease than mosquitoes, houseflies (Musca domestica) are mechanical transmitters of the disease. The chemical control carried out until now has brought about the emergence of resistance of houseflies against DDT and many other insecticides including organophosphates and carbamates. In order to look for an alternative insecticide which can control houseflies, a study was performed on the efficacy of insecticide belonging to the synthetic pyrethroid group containing 30 g/l of the active substance such as alphacypermethrin. Four dosages of insecticide with active ingredient of 30 g/l alphacypermethrin at dosages of 17.5 ml/ha, 35 ml/ha, 50 ml/ha and 70 ml/ha respectively wereused by fogging against houseflies kept in cages. The result showed that dosages of 35 ml/ha, 50 ml/ha and 70 ml/ha were all effective to kill M. domestica.
PENGARUH PEMBERIAN EKSTRAK DAUN KOLA (COLA NITIDA) PADA KUALITAS SPERMA MANUSIA IN VITRO Susmiarsih, T.; Endrini, Susi
Jurnal Kedokteran YARSI Vol 21, No 1 (2013): JANUARI - APRIL 2013
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (125.797 KB) | DOI: 10.33476/jky.v21i1.15

Abstract

Studi terhadap tanaman yang berpengaruh terhadap proses reproduksi masih menjadi skala prioritas. Salah satunya adalah Kola (Cola  nitida), yang dikenal mempunyai efek stimulan. Telah dilakukan studi untuk mengetahui pengaruh ekstrak daun Kola terhadap viabilitas, motilitas dan integritas membran spermatozoa manusia in vitro. Sampel sperma diperoleh dari 20 orang pria dengan kategori normozoospermia. Sampel semen dibagi menjadi 1 kelompok kontrol ( kontrol negatif) dan 2 kelompok perlakuan dengan ekstrak daun Kola (0.05% dan 0.025%). Hasil penelitian menunjukkan bahwa ekstrak daun Kola tidak berpengaruh terhadap viabilitas spermatozoa tetapi secara bermakna meningkatkan motilitas dan integritas membran spermatozoa (p 0.05). Hasil ini mengindikasikan bahwa ekstrak daun Kola berpengaruh terhadap kualitas spermatozoa manusia in vitro.Study on medicinal plants that have potential effect on  reproductive process is still important to be done. One of the plant is Kola (Cola nitida) that has a stimulant effect. This study evaluated  the effects of Kola  leaf  extract  toward viability, motility and membrane integrity on human sperm in vitro. Normozoospermia semens from  twenty volunteers were taken and divided into 3 groups: 1 group  was  treated  as control  and 2 groups were treated with Kola leaf extracts  (0.05% dan 0.025%). The results showed that Kola leaf extract  had no significant effect in viability but increased significantly (p 0.05) the motility and membrane integrity. It indicates that Kola leaf extract influences human semen quality in vitro.
GAMBARAN DAN KEADAAN MASYARAKAT TERHADAP MALARIA DI KECAMATAN SEBATIK KABUPATEN NUNUKAN, PROVINSI KALIMANTAN TIMUR (DAERAH LINTAS BATAS INDONESIA–MALAYSIA) Boesri, Hasan
Jurnal Kedokteran YARSI Vol 24, No 2 (2016): MEI - AGUSTUS 2016
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jky.v24i2.255

Abstract

Perilaku Masyrakat daerah endemis merupakan penentu akan adanya kasus malaria, meskipun lingkungan mendukungnya. Jika masyarakat mau merobah lingkungan yang tidak baik menjadi lingkungan yang bersih penyakit akan sulit menjadi endemik. Telah dilakukan penelitian mengenai perilaku masyarakat di pulau sebatik terhadap penularan malaria dengan hasil sebagai berikut: Perilaku penduduk berisiko tertular malaria adalah kegiatan keluar rumah pada malam hari dan tidak menggunakan pelindung diri dari gigitan nyamuk. Pengetahuan masyarakat masih rendah terhadap penularan malaria serta ditemukan keterlambatan serta pengobatan tidak tuntas. Meningkatkan penyuluhan kepada masyarakat tentang cara perlindungan diri/keluarga supaya tidak tertular malaria. Usaha pencegahan terjadinya penularan malaria: Meningkatkan surveilan kasus terhadap pendatang dan pengobatan kepada penderita. Dilakukan pelatihan penyegaran kepada mikroskopis di Puskesmas untuk mengurangi kesalahan pemeriksaan slide darah (penentuan spesies parasit). Perlu dilakukan pelatihan entomologi bagi staf Puskesmas, untuk pemantauan nyamuk vektor, sebagai usaha pencegahan dini penularan malaria.
INFEKSI NEMATODE USUS PADA SISWA SEKOLAH DASAR NEGERI (SDN) KARANG MULYO 02, KECAMATAN PEGANDON, KABUPATEN KENDAL Maharani I.P, Astri
Jurnal Kedokteran YARSI Vol 13, No 1 (2005): JANUARI - APRIL 2005
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.285 KB) | DOI: 10.33476/jky.v13i1.1047

Abstract

The intestinal helminth infection was suffered mostly by pre-elementary and elementary students. This work was conducted to study the relationship between hygiene sanitation and intestinal helminth infection and the relationship between intestinal helminth infection and nutrition status in the students of SDN Karang Mulyo 02, Pegandon District, Kendal Regency. Survey method with a cross sectional approach was used in this study. The result showed that 21,57% of 51 subjects suffered intestinal helminth infection and the most common infection was a combination of Necator americanus and Ancylostoma duodenale infection. Hygiene sanitation of 74,51% respondens was good, however the nutrition status of the students was mostly bad according to weight to age as well as height to age, indicates i.e 56,87% out of 51 respondens. The energy and protein levels were less than standard and employing chi square analysis a positive correlation was found between hygiene sanitation and intestinal helminth infection but a negative correlation was found between intestinal helminth infection and nutrition status
GAMBARAN HISTOLOGIS LIMFA (LIEN) SETELAH PAPARAN MADU PADA TIKUS PUTIH (RATTUS NORVEGICUS) Nurul Hidayah, Fitria; Nabawiyati Nurul Makiyah, Sri
Jurnal Kedokteran YARSI Vol 13, No 1 (2005): JANUARI - APRIL 2005
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.881 KB) | DOI: 10.33476/jky.v13i1.1052

Abstract

Honey is a special food because of the taste, nutrition, and high benefits of it. Honey?s effect to healing process also as well known already and has been reported, even the benefits of honey written in Holy Quran. Honey also has an antimicrobial effect because it produces hydrogen peroxide, nonperoxide component effect, acidity, immune system stimulation, and honey viscosity as the barrier against pathogenic bacteria. This scientific paper is presented to observe the stimulation of the effect of the immune system of honey in the lymph after the honey exposure. This research is observational, using experimental approach, which is done by using male white mice (Rattus norvegicus), with a body weight ± 220 gram, expose with honey for as long 35 days. The mice are divided into two groups, the control group and the treatment group. Each group consist of five mice. After the treatment, the mice are decapitated, and then the lymph are collected. The immune system activation in the lymph is estimated by measuring the white pulp diameter which will be compared between that of the treatment group and the control group. As the result of the observation, is obvious that the diameter of the white pulp in the treatment group is less than that of the control group. From the result of the statistical analysis, the significances counted 0,006 (p 0,05). It shows that there are significant differences between those two groups, and also proves that honey has indeed the effect to support the peripheral immune system.
EFEKTIVITAS VECTOBAC DAN PREDATOR MESOCYCLOPS ASPERICORNIS SEBAGAI JASAD PENGENDALI HAYATI JENTIK AEDES AEGYPTI DALAM GENTONG AIR Ambar Yuniarti, Retno; Ch.P, Blondine
Jurnal Kedokteran YARSI Vol 13, No 1 (2005): JANUARI - APRIL 2005
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (172.14 KB) | DOI: 10.33476/jky.v13i1.1057

Abstract

Dengue Haemorrhagic Fever (DHF) was one of the acute and infectious disease and was still a problem of public health in Indonesia. This was caused the spread of the Aedes aegypti mosquito in the country, except at the altitude of more than one thousand meters above sea level. The spread of DHF was connected with the breeding place of the DHF vector. The use of chemical insecticides for vector control has been conducted for some time. Frequent use of insecticides has caused resistence of the mosquito towords the insecticide. Nowdays, biological control agents was developed. The aim of the study is to know the effectivity of the VectoBac and Mesocyclops aspericornis predator both applied individually and combination for controling of Ae. aegypti larvae in the water jar. The study was conducted in January until August 2003 in a DHF endemic area at Kupang Rengas, Kupang Village, Ambarawa subdistrict, Semarang regency, Central Java. The design of the study was quasy experimental comparing before and after intervention using external difference groups. Purposive sampling was conducted. The ten sample size were used for each treatment. The result showed that VectoBac was effective to reduce the Ae. aegypti larvae density until the fifth week reaching a percentage of 79,31 ? 96,04%. M. aspericornis predator was effective to reduce the Ae. aegypti larvae density in the seventh week until the twelfth week was  70,69 ? 75,09%. The combination of VectoBac and M. aspericornis predator was effective to reduce Ae. aegypti larvae density until the twelfth week reaching a percentage of 96,56 ? 100%.
PENYAKIT WALDENSTROM MAKROGLOBULINEMIA Purnamasari, Endah; Wirawan, Riadi
Jurnal Kedokteran YARSI Vol 23, No 1 (2015): JANUARI - APRIL 2015
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (194.605 KB) | DOI: 10.33476/jky.v23i1.95

Abstract

Penyakit Waldenstrom Makroglobulinemia adalah kelainan limfoproliferatif sel B yang tidak umum, ditandai dengan infiltrasi sumsum tulang dan produksi immunoglobulin monoklonal IgM. Kami melaporkan suatu kasus penyakit Waldenstrom Makroglobulinemia. Sampel darah EDTA dan sediaan sumsum tulang diterima di laboratorium untuk dilakukan pemeriksaan hematologi lengkap, gambaran darah tepi, dan pemeriksaan sediaan sumsum tulang.Waldenstrom?s macroglobulinemia (WM) is an uncommon B-cell lymphoproliferative disorder characterized by bone marrow infiltration and production of monoclonal immunoglobulin (Ig) M. We reported a case of Waldenstrom?s disease. An EDTA blood and bone marrow biopsy sample from a man of 58 years old was ordered to be analyzed for routine peripheral blood assessment and morphology, erythrocyte sedimentation rate (ESR), and bone marrow morphology.
HUBUNGAN MEROKOK DENGAN KEJADIAN TUBERKULOSIS PARU DI PROVINSI SULAWESI UTARA BERDASARKAN DATA RISKESDAS TAHUN 2010 Ernawati, Kholis
Jurnal Kedokteran YARSI Vol 25, No 1 (2017): JANUARI - APRIL 2017
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (167.236 KB) | DOI: 10.33476/jky.v25i1.277

Abstract

Tuberkulosis (TB) adalah suatu penyakit infeksi menular yang disebabkan bakteri Mycobacterium tuberculosis, yang dapat menyerang berbagai organ,terutama paru-paru. Merokok merupakan salah satu faktor risiko yang penting pada kejadian TB. Tujuan penelitian ini untuk mengetahui hubungan kebiasaan merokok dengan kejadian Tuberkulosis Paru di Provinsi Sulawesi Utara berdasarkan data Riset Kesehatan Dasar (Riskesdas) tahun 2010. Metode penelitian ini menggunakan metode deskriptif korelatif. Sampel penelitian adalah total sampling dari semua data responden Riskesdas tahun 2010 di Provinsi Sulawesi Utara yang berusia ? 15 tahun berjumlah 2.319 responden. Metode analisis yang digunakan adalah univariat dan bivariat. Hasil penelitian menunjukkan angka kejadian TB Paru di Provinsi Sulawesi Utara Riskesdas tahun 2010 sebesar 47 orang (2,6%), orang yang mengonsumsi rokok setiap hari sebesar 593 orang (33,4%), dan hasil analisis bivariat menunjukkan nilai signifikansi  p = 0,489 (0,489 0,05) yang artinya tidak terdapat hubungan antara kebiasaan merokok dengan kejadian TB Paru. 
EFEK CORIANDRI FRUCTUS (KETUMBAR) TERHADAP SLOW WAVE SLEEP (SWS) Indrawati, Lili; D. Sitorus, Truly
Jurnal Kedokteran YARSI Vol 15, No 3 (2007): SEPTEMBER-DESEMBER 2007
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.932 KB) | DOI: 10.33476/jky.v15i3.1073

Abstract

Traditional remedies have been used by Indonesian people for centuries. One of them which is empirically used as hypnotic sedative is coriandri fructus. The objective of this study was to find out whether cariandri fructus could be used as a sleep medicine by measuring the sleep quality induced. In this study, a true experimental design was employed. Applying a purposive sampling method, 11 apparently healthy adult male fulfilling the inclusion criteria were selected. Each subject was induced to sleep three times, 7.5 hours each and observation through overnight polysomnography was carried out following each treatment. Lorazepam, placebo and coriandri fructus was used to induce the first, second and third sleep respectively. Parameters used in this experiments were Latency to Slow Wave Sleep, Total Time in SWS, and the distribution of SWS.  This study showed that Lorazepam tend to suppress the Latency to SWS compare with the control and Coriandri fructus. There was no SWS deprivation in all groups. Lorazepam tend to suppress SWS on the last 2,5 hours of sleep.

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