cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Beny Irawan
Contact Email
benyirawan77@gmail.com
Phone
-
Journal Mail Official
benyirawan77@gmail.com
Editorial Address
-
Location
Kab. deli serdang,
Sumatera utara
INDONESIA
JURNAL FARMASIMED (JFM)
Published by Institut Kesehatan Medistra Lubuk Pakam
ISSN : -     EISSN : 26550814     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Jurnal FARMASIMED (JFM) Volume I Nomor 1 Periode Mei - Oktober Tahun 2018. Jurnal ini memberikan ruang bagi akademisi, peneliti dan pengguna hasil penelitian dan pengabdian untuk mendiseminasikan, menginformasikan, mendiskusikan dan menggunakan hasil penelitian dan pengabdian sebagai upaya meningkatkan kualitas kebijakan di bidang farmasi yang berbasis ilmiah dan dapat dipertanggung jawabkan. Jurnal ini menyajikan hasil penelitian, pengabdian masyarakat serta artikel ilmiah di bidang farmasi.
Arjuna Subject : -
Articles 33 Documents
 1   2   3   4 
Search results for , issue "Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)" : 33 Documents clear
Test to Determine The Quercetin Content of Tenggiang (Polystichum setiferum) Using the High Performance Liquid Chromatography (HPLC) Method and Its Antifungal Activity Against Pityrosporum ovale Turnip, Nur Ulina M. Br.; Ratih Anggraeni; Sihombing, Yanna Rotua; Suci Wulandari
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2361

Abstract

Background: Indonesia is a country with high temperature and humidity, which are supporting factors for the development of microbes. One of the microbes that causes infection is the fungus Pityrosporum ovale which can cause dandruff, especially on the scalp. Treatment is usually done using shampoo containing an antidandruff formula. Synthetic chemicals used in hair care have been widely known and used to treat various infections caused by fungi. Tenggiang, a shrub originating from the Toba Samosir area, is used empirically as a wound medicine. In previous studies, Tenggiang has been shown to have antimicrobial, antioxidant, and anti-inflammatory effects. This is related to the content of secondary metabolites found in tenggiang, such as flavonoids, terpenoids/steroids, saponins, and phenolics. Flavonoids, which are secondary metabolites of the polyphenol group. Objective: to measure the levels of quercetin in tenggiang using the HPLC method and to evaluate its antifungal activity against Pityrosporum ovale. Method: measurement of quercetin using the HPLC method and measurement of antifungal activity using the Kirby-bauer method. Results: The measurement results were then calculated as quercetin equivalents, the extract contained a total of 1.33% flavonoids. The retention time data of the standard quercetin was 5.405 minutes and the retention time of the ethanol extract of mackerel was 5.332. The ethanol extract of mackerel was  said to contain quercetin because it had a retention time that was relatively the same as the retention time of the standard quercetin. The extract also showed potential as an antimicrobial agent, where an increase in extract concentration was directly proportional to an increase in the diameter of the inhibition zone. In addition, when compared to the blank, the resulting difference was statistically significant (p <0.05). Conclusion: Tenggiang, extract has antifungal activity and antioxidant potential.
Formulation and Evaluation of Maggot Extract Nanocream (Hermatia illucens) as a Future Anti-Aging Candidate Situmorang, Novidawati Boru; Marbun, Romauli Anna Teresia
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2399

Abstract

Background: Premature aging is a serious problem, especially for women. Skin aging is mainly caused by solar radiation. Ultraviolet (UV) A and B rays from sunlight induce the formation of reactive oxygen species in the skin and cause oxidation. Antioxidants are compounds that can neutralize free radicals by slowing down oxidation reactions. Maggots are widely consumed by the public and used as topical medicines because they have high levels of lauric acid, which acts as an anti-inflammatory, antibacterial, and antiprotozoal. Purpose: to analyze the formulation of nanocream preparations, antioxidant activity and evaluate the physical stability of maggot extract nanocream. Research method: The method used was the maceration method with n-hexane, antioxidant testing using the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) method, and testing the physical stability of the preparation. The results of the antioxidant activity test showed an IC50 value of maggot extract of 40.36 ± 1.21 µg / mL. Results: It shows that the sample has very strong antioxidant activity. Based on the organoleptic test, the nanoceram preparation in Formula 1, 2, 3 and 4 has a milky white color which is influenced by the difference in the amount of extract, a distinctive aroma and semi-solid consistency. The pH examination of nanocream preparation must be adjusted to the skin pH, which is 5-7. The results of the viscosity test on the maggot extract have met the requirements, which are 2,000-5,000 cps. Conclusion: formulation and evaluation of the nanocream extract meet the requirements as a good nanocream and have the ability as an anti-aging.
Test Of Antibacterial Activity and GC-MS analysis of ethyl acetate and N-hexane fractions of Kenitu leaves (Chrysophyllum cainito L.) Megawati, Sefi; Meta Safitri; Rangkuti, Saru Noliqo; Luthfiyyatul Makiyyah; Arum Mawarni, Nur Indah
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2421

Abstract

Background: As a result of the large number of infectious diseases, every year 3.5 million people die. The more microorganisms that are resistant to antibiotics, the search for and research into new antibacterials must be carried out from medicinal plant extracts such as the kenitu leaf plant, whose antibacterial activity is still rarely researched. Objectives: to analyze the factors that influence the management of solid media waste of hazardous and toxic materials at RSUD.Kumpulan Pane, Tebing Tinggi City. Research method: This research is a type of laboratory experiment using the semi-polar solvent ethyl acetate and the non-polar solvent n hexane from kenitu (Chrysophyllum cainito L.) leaves to test their antibacterial activity using the disk diffusion method. In this study there were six treatment groups: positive control (+) ciprofloxacin, negative control (-) DMSO 10%, as well as four concentration variations, namely K1: 25 mg/ml, K2: 50 mg/ml, K3: 100 mg/ml, and K4: 500 mg/ml. Results: The results of the ANOVA test of the antibacterial activity test of the Bacillus subtilis fraction against the ethyl acetate fraction obtained a p value <0.001. From the results of the homogeneity test, a significant value of p = 0.023 was obtained. These values ??are in accordance with the criteria (p <0.05), meaning that the concentration treatment has a significant impact on the diameter of the inhibition zone. Based on the results of the two tests, the data obtained in this study were analyzed using the non-parametric Kruskal-Wallis statistical test showing that there was a difference in the average Asymp value in each treatment. Sig. = 0.005 (p <0.05). The results of the Mann-Whitney test of the ethyl acetate fraction on Bacillus subtilis bacteria stated that it had a significant difference in providing an inhibition zone. Conclusion: the analysis stated that there were 27 compounds that were identified in the ethyl acetate fraction and 19 compounds that were identified in the n-hexane fraction of kenitu leaves. The results of testing regarding antibacterial activity stated that the kenitu leaf fraction from ethyl acetate solvent was only able to inhibit the growth of Bacillus subtilis and Staphylococcus aureus bacteria at a concentration of 500 mg/ml, for the kenitu leaf fraction from n-hexane solvent stated that all concentrations were not possible. able to inhibit the growth of Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Bacillus subtilis.
The Effect of Giving Green Apple (Malus Domestica) Juice on the Histopathology of White Rat Pulmonary Organs Induced by Cigarette Smoke Pranata, Chandra; Asti Pratiwi
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2437

Abstract

Background: Cigarette smoke contains oxidants or free radicals and around 4700 dangerous chemicals. The high level of free radicals in the body triggers the emergence of Reactive Oxygen Species (ROS) which results in oxidative stress, this can occur if there is an imbalance between the amount of oxidants and antioxidants. In this process, there is a leak of O2 which will turn into superoxide radicals (*O2) which can form pro-inflammatory cytokines such as IL-6. Objective: to identify the effect of exposure to cigarette smoke on the histopathological appearance of rat lungs. Method: This research uses Post Test Only Control Group Design. Samples were taken from 20 male rats that met the inclusion criteria and were randomly divided into 4 groups, namely K1, K2, K3, and K4. K3 was given standard feed plus green apple juice at a dose of 13.5 grams/day. Meanwhile, the K4 group was given standard feed plus green apple juice at a dose of 27 grams/day. However, both were given exposure to cigarette smoke for 14 days. On the 15th day, blood was taken from male Wistar rats to carry out a histopathological examination of the rats' lungs using Hematoxillin-Eosin staining. Results: The results showed that there was damage in the negative group when compared with the normal group and the highest improvement in lung tissue was found at a dose of 27 grams/day when compared with the negative and normal groups. Conclusion: There is an effect of giving green apple juice on IL-6 and SOD levels in mice exposed to cigarette smoke.
An Overview of The Implementation of Pharmaceutical Service Standards at Puskesmas in Tarakan City in 2024 Syam, Siti Muti'ah; Irma Novrianti; Jufri Ubrusun
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2439

Abstract

Pharmaceutical services that are guided by Permenkes No. 74 of 2016 in the form of presentation and accountability for patients who are directly related to pharmaceutical products at public health centers throughout Tarakan City to become a starting point for optimizing service quality and supporting the progress of the health sector that contributes comprehensively. The purpose of the study was to describe the implementation of pharmaceutical service standards in all community health centers in Tarakan City. Descriptive strategy observation research method through survey media. The results of research on 6 Puskesmas that have a pharmacist in charge can be described that the implementation of pharmaceutical service standards has been successfully implemented in all Puskesmas of Tarakan City by 83.5%, covering the first aspect of clinical pharmacy (69.1%) and the second aspect of the management of pharmaceutical preparations and consumable medical materials (97.9%). The study concluded that most of the implementation was dominated by the Pharmacist in Charge (53.6%), followed by Pharmacy Vocational Workers (24.2%) and Pharmacist Assistants (5.6%).
Evaluation of Lotion Formulation Using Salam Leaf Extract (Syzygium polyanthum) with Antioxidant Activity Ambarita, Petrus Alvin Peter; Veni Putri Nurhayati; Tia Azzahra Putri; Tifani Pardede; Shefia Dhiya Khansa; Herayati
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2440

Abstract

Bay leaves (Syzygium polyanthum) contain active compounds such as tannins, saponins, flavonoids, and steroids, which offer various benefits in skincare, including antioxidant, antimicrobial, anti-inflammatory, and natural cleansing properties. This study aimed to evaluate the antioxidant activity of bay leaf extract and assess the quality of lotion formulation containing the extract. Extraction was carried out using the maceration method with 70% ethanol as the solvent, and antioxidant activity was tested using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, yielding an IC50 value of 48.64 ppm, indicating moderate antioxidant activity. The lotion formulations were evaluated for organoleptic properties, homogeneity, pH, spreadability, viscosity, and emulsion stability. Results showed that formula F2 had superior quality compared to F1, with a spreadability of 6.5 cm (compliant with SNI 16-3499-1996), pH 6.70 (safe range 4.5–8), creamier texture, lower stickiness and greasiness, and faster absorption time (30 seconds). Formula F2 also demonstrated ideal viscosity (6805 mPaS) and shear thinning properties (torQ 68.1%), which ease application on the skin. Based on these findings, formula F2 meets the requirements for topical cosmetics according to SNI and the Indonesian Pharmacopoeia VI edition, especially in terms of pH, physical stability, and viscosity, and thus shows promising potential for development as a natural-based cosmetic product that is both safe and effective in protecting the skin from free radicals and irritation.
Formulation and Antioxidant Activity Test Of Body Lotion Preparation of Ethanol Extract of Sky Mustard Leaves (Cyanthillium cinereum (L) H.Rob) As A Moisturizer Ika Julianti Tambunan; Siti Muliani
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2441

Abstract

The skin is the first protection to ward off free radicals. Cosmetics used on the skin throughout the body are body lotions. The content of the sky mustard leaves (Cyanthillium cinereum (L) H. Rob) are alkaloid compounds, phenols, saponins, steroids, tannins, and flavonoids that function as antioxidants. This study aims to determine the antioxidant activity of the formulation of body lotion preparations of ethanol extract of sky mustard leaves. This study was conducted using an experimental method. The method of maceration of sky mustard leaves (Cyanthillium cinereum (L) H. Rob) using 96% ethanol. The methods used include selecting a standard formula, making body lotion preparations in concentrations of 1%, 1.5%, 2% and blanks, as well as evaluating the physical quality of the preparations and testing antioxidant activity using the DPPH method. The results showed that the leaves of the sky mustard (Cyanthillium cinereum (L) H. Rob) can be formulated into a body lotion preparation. The preparation obtained was stable and homogeneous, an oil-in-water emulsion type, pH immediately after being made 5.6 - 6.0 and after the cycling test 6.0 - 6.05, with a viscosity value of 2,300-4750 mPa's. The body lotion preparation of the sky mustard leaves with a concentration of 2% was the best preparation with a recovery percentage of 57.53% and an IC50 value of 61.38 ppm, including the "strong" category. The extract of the sky mustard leaves had an IC50 value of 14.75 ppm, which was categorized as "very strong". The blank preparation had an IC50 value of 156.91 ppm, including the "moderate" category.
Analysis of Antioxidant Potential of Infusion from Variations in Particle Size of Cinnamon Leaves Simplicia (Cinnamomum burmannii) using the DPPH Method Kasmadi, Fathnur Sani; Maulida, Dafa Riska; Jannah, Zahratul; Yuliawati, Yuliawati
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2455

Abstract

Background: The Cinnamon plant is used as herbal therapy and spices for cooking food in Indonesia. The content of secondary metabolite compounds has the potential as an antioxidant. Variations in particle size have been proven to have the potential to attract compounds from herbal plants. Purpose: The research aimed to determine the antioxidant potential of cinnamon leaf infusion with different simplicia particle sizes. Method: The research method used in this research was the DPPH method, using Vitamin C as a comparison, and the concentration of simplicia used to make the infusion is 5%. Result: The test results showed that a 5% infusion of simplicia microparticles had higher antioxidants than simplicia infusion with an IC50 value of 74.89 ppm, which was included in the classification of strong antioxidant activity. In contrast, the IC50 value of simplicia infusion was 110.61 ppm, which was classified as moderate. Conclusion: The infusion of simplicia microparticles from cinnamon leaves can be developed as an alternative antioxidant from natural ingredients.
Overview of Sales And Investment of Hard Drugs in Pharmacy “X” In Pamusian Village, Tarakan City With ABC Analysis For The Period Of October 2023 – October 2024 Iqradiya, Azdyra; Heriani; Sari Wijayanti
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2459

Abstract

Background: This study aims to evaluate the sales and investment of hard drugs at Pharmacy "X" Pamusian Village, Tarakan City, using the ABC analysis method during the period from October 2023 to October 2024. Objectives: The ABC analysis method is applied to group drugs into three categories based on investment value and contribution to sales. Research method: The data analyzed include sales of hard drugs, investment value, and pharmacology categories. Results: The results of the study show that out of a total of 169 hard drug items, group A consists of 48 items with the highest investment value, group B includes 45 items with moderate contributions, and group C consists of 76 items with the lowest investment value. This grouping provides guidance for pharmacies in managing stock and investment more efficiently to meet market needs. Conclusion: In conclusion, the ABC analysis method helps Pharmacy "X" in prioritizing capital management and increasing operational efficiency by focusing on drug groups that have the greatest impact on sales.
Profile Of The Use Of The Drug In Patients Acute Respiratory Tract Infection In Child Patients Aged 5-10 Years: Profil Penggunaan Obat Pada Pasien Infeksi Saluran Nafas Akut (ISPA) Pada Pasien Anak Usia 5-10 Tahun irma novrianti, Irma
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2462

Abstract

Acute respiratory tract infection  is a disease that is often experienced by toddlers and children caused by bacterial, viral infections, without or accompanied by lung parenchyma. The purpose of this study was to determine the therapy used in ARI patients at the Puskesmas "X" in Tarakan City in the period January-July 2023. This study was experimental with a descriptive method. Sampling was carried out using simple random sampling with a retrospective approach in the period January-July 2023. The research data were grouped and analyzed descriptively and presented in the form of tables and percentages. Based on the results of the study, the most widely used treatments in prescriptions were mucolytics (98.2%), antihistamines (95.7%) and analgesics-antipyretics (70.6%) and the least were antiasthma (4.0%), antibiotics (1.8%) and Corticosteroids (1.2%). The most widely used types of drugs in prescriptions are ambroxol (98.2%), CTM (95.7%), and paracetamol (69.7%) and the least used are Dexamethasone (1.2%), ibuprofen 200 mg (0.9%), and vitamins (12.8%). It can be concluded that the most widely used drug in the treatment of ARI is mucolytic drugs (ambroxol) and the least used drug is corticosteroids, example dexamethasone.

Page 1 of 4 | Total Record : 33

 1   2   3   4 

Filter by Year

2025 2025


Reset
Filter By Issues
All Issue Vol 8 No 1 (2025): Jurnal Farmasimed (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM) Vol 6 No 2 (2024): Jurnal Farmasimed (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM) Vol 5 No 1 (2022): Jurnal Farmasimed (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM) Vol 4 No 1 (2021): Jurnal Farmasimed (JFM) Vol 3 No 2 (2021): Jurnal Farmasimed (JFM) Vol 3 No 1 (2020): Jurnal Farmasimed (JFM) Vol 2 No 2 (2020): Jurnal Farmasimed (JFM) Vol 2 No 1 (2019): Jurnal Farmasimed (JFM) Vol 1 No 2 (2019): Jurnal Farmasimed (JFM) Vol 1 No 1 (2018): Jurnal FARMASIMED (JFM) More Issue