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Lukas Widhiyanto, dr., SpOT(K)
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INDONESIA
Journal Orthopaedi and Traumatology Surabaya (JOINTS)
Published by Universitas Airlangga
ISSN : 2722712X     EISSN : 24608742     DOI : 10.20473/joints.v10i2.2021.39-45
Core Subject : Health,
Health Professions Medicine & Pharmacology
The JOINTS research topics are relating to education and training in the field of orthopedics and traumatology, including research reports, case reports, and literature reviews.
Arjuna Subject : Kedokteran - Ortopedi dan Kedokteran Kesehatan
Articles 103 Documents
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Hypergravity as a Possible Way of Bone Tissue Engineering in Osteoblastic Differentiation from Mesenchymal Stem Cells: A Systematic Review Sudrajad, Wisnu; Indrawan, Andre Erica; Kusuma, Devangga; Soetojo, Bagus Wibowo; Suroto, Heri
Journal Orthopaedi and Traumatology Surabaya Vol. 13 No. 2 (2024): October 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v13i2.2024.75-83

Abstract

Background: Tissue engineering development has become a highlight in recent decades. One of the key areas of focus is producing mature bone tissue to overcome orthopedic problems, such as bone defects. Various cultures have been implemented on stem cells; some induce osteoblastic differentiation markers, while others have the opposite effect. Microgravity has been proven in several studies to inhibit the expression of osteogenic differentiation markers. Conversely, hypergravity is expected to have the opposite impact, supporting stem cells in the osteogenesis pathway. Methods: A literature search was conducted using online databases including Sciencedirect, PubMed, and Proquest, covering the period from 2008 to 2022. This search considered only experimental studies published in English. The keywords used in this research were "hypergravity" and "mesenchymal stem cell." All acquired data were processed and analyzed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines (2020). Results: Initially, 190 studies were collected from online databases based on relevant keywords. After screening, 5 studies were included in the final analysis, focusing on hypergravity treatment and its effects on mesenchymal stem cells (MSCs). Conclusion: Hypergravity shows a significant and strong impact on osteoblastic differentiation. This study revealed that a gravity force of 30G and a culture duration of 7 to 14 days are the most optimal combination for inducing osteoblastic differentiation in MSCs.
Effects of Neoadjuvant Denosumab on Radiological and Histological Responses in Patients Undergoing En Bloc Resection for Giant Cell Tumor of Bone: A Systematic Review Aditama, Hendra; Pratama, Yo Tendy; S, Dhanan Prastanika; K, Dita Anggara; S, Rhyan Dharma
Journal Orthopaedi and Traumatology Surabaya Vol. 13 No. 2 (2024): October 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v13i2.2024.100-110

Abstract

Background: Giant cell tumor of bone (GCTB) is a rare primary bone tumor. The standard treatment is en bloc resection, which can be challenging due to tumor size or location. Denosumab, a monoclonal antibody, has emerged as a promising neoadjuvant therapy for GCTB, potentially facilitating surgical resection. However, its optimal use remains unclear, with debate surrounding its impact on local recurrence. This systematic review aims to synthesize evidence on the histological and radiological changes induced by neoadjuvant denosumab and its impact on surgical outcomes. Methods: This review followed PRISMA guidelines. The medical term "denosumab", "neoadjuvant", "GCTB", "radiological", and "histological" were used in PubMed (423 articles) and Google Scholar (18,100 articles), totaling 18,523 articles to discover studies of the effect of neoadjuvant denosumab on radiological and histological response up to July 2023. Six remaining studies were reviewed and screened for inclusion criteria based on their relevance to the study subject and clinical outcomes. Results: Based on six studies in this review, five showed histological response by decreasing the multinucleated giant cells and osteoclasts after neoadjuvant DT. Six studies showed increased significant bone reconstitution as a radiological response in the GCTB locale, replaced the extending tumor into soft tissue by abundant bone production with peripheral shell, and increased ease of en bloc resection. Conclusions: Neoadjuvant denosumab therapy shows promise in managing giant cell tumors of bone (GCTB) by reducing osteoclasts, shrinking tumor volume, and promoting cortical bone formation, thus facilitating en bloc resection. However, further research is needed to confirm these findings.
Suppurative Flexor Tenosynovitis: A Case Report Wibowo, M.D., Pramono Ari; Adnani, Arham
Journal Orthopaedi and Traumatology Surabaya Vol. 13 No. 2 (2024): October 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v13i2.2024.111-116

Abstract

Background: Suppurative flexor tenosynovitis is an infection of the flexor tendon sheath. This case report presents the clinical course and management of a patient diagnosed with suppurative flexor tenosynovitis. The diagnosis is based on history taking, physical examination, and supporting examination findings. Case Report: A 42-year-old man presented with chief complaints of pain, swelling, and immobility of the index finger of his right hand after being pierced by a fish spine 3 days prior. Physical examination revealed the second digit in a slightly flexed and swollen position, with pain elicited on palpation and passive extension, limiting the patient's range of motion. The patient was diagnosed with suppurative flexor tenosynovitis and treated with antibiotics, debridement, and drainage. Postoperative results were good, with no signs of complications such as spread of infection, tendon necrosis, osteomyelitis, or indications for amputation.Discussion: The treatment for suppurative flexor tenosynovitis involves a combination of antibiotics and surgery. Surgical interventions typically include open drainage and debridement or closed catheter irrigation. Additionally, postoperative rehabilitation is a crucial aspect that requires careful consideration, as it has been shown to accelerate the healing process.Conclusion: Suppurative flexor tenosynovitis is a rare but serious condition that demands early detection and a multidisciplinary approach. Timely surgical debridement and targeted antibiotics, guided by the identification of the causative organism, are essential for positive patient outcomes.
Profile of Lumbar Spinal Stenosis Patients at Dr. M. Djamil Central Public Hospital from 2018-2022 Akbar, Inasa Faiza; Sahputra, Roni Eka; Elfi, Eka Fithra; Rahmadian, Rizki; Rusjdi, Dina Arfiani; Silvia, Nelmi
Journal Orthopaedi and Traumatology Surabaya Vol. 13 No. 2 (2024): October 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v13i2.2024.52-60

Abstract

Background: Lumbar Spinal Stenosis (LSS) is a pathological condition characterized by narrowing of the spinal canal in the lower back. In Indonesia, comprehensive data on LSS is currently unavailable. This study aimed to determine the profile of LSS patients at Dr. M. Djamil Central Public Hospital. Methods: This descriptive cross-sectional study utilized medical record data from 122 LSS patients at Dr. M. Djamil Central Public Hospital between 2018 and 2022, selected via consecutive sampling. Inclusion criteria included age over 18 years and a confirmed LSS diagnosis. Exclusion criteria included incomplete medical records, lack of MRI results, and follow-up visits without treatment. Univariate analysis was performed using SPSS 25.0 to describe patient characteristics, causative factors, symptoms, location of stenosis, and management type. Results: In this study, 122 samples met the inclusion and exclusion criteria. LSS was mainly found in patients aged 60-69 years (33.6%) and in women (59%). Most LSS patients had obesity (BMI category I, 32%). Many LSS patients were housewives (42.62%) and reported light work activity (63.1%). The most common cause of LSS was degenerative factors (59%). The main symptom experienced by LSS patients was lower back pain (94.3%), frequently accompanied by radicular pain (79.5%). The most common location of stenosis was L4-L5 (43.4%). Most LSS patients in this study were managed both conservatively and operatively (70.5%). Conclusion: These findings contribute to a better understanding of LSS prevalence and distribution among patients. Further multicenter studies are needed to establish a comprehensive national LSS profile.
Correlation Between Shoulder Pain Severity, Acromion Morphology, and Acromiohumeral Distance Using MRI: A Study at Haji Adam Malik Hospital Medan in 2022 Albar, Husnul Fuad; Rendy, Geon; Nanto, Iman Dwi
Journal Orthopaedi and Traumatology Surabaya Vol. 13 No. 2 (2024): October 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v13i2.2024.69-74

Abstract

Background: Studies have shown that rotator cuff tears (RCTs) are the most common cause of shoulder pain and restricted movement. The acromion is a posterior shoulder landmark. Specific acromion morphologies may predispose individuals to rotator cuff tears. Furthermore, studies have found a correlation between supraspinatus tendon tears and acromiohumeral distance. This study examines how shoulder pain assessed with American Shoulder and Elbow Surgeons (ASES) score relates to acromion morphology and acromiohumeral distance on MRI at Haji Adam Malik Hospital in 2022.Methods: This descriptive analytical study employed a cross-sectional approach. A total of 38 patients with a confirmed diagnosis of shoulder pain underwent shoulder MRI examinations and were assessed using the ASES score. Statistical analysis included assessing data normality and performing Spearman correlation analysis. Data were processed and analyzed using SPSS version 25.0.Results: In this study of 38 patients, most participants were women with an average age of 54.66 years. The most common acromion type was type 1 (flat), and the most frequent acromiohumeral distance category was normal. There was no correlation between acromion type and ASES scores, but a moderate correlation was found between the scores and acromiohumeral distance (p=0.016). A positive correlation was observed between type III acromion and ASES score. Conclusion: Shoulder pain based on ASES score has a moderate correlation with acromiohumeral distance and acromion type III variation has a positive correlation although there is no significant correlation was found between shoulder pain and acromion type.
Characteristics and Management of Neck and Trochanteric Femur Fractures at a Tertiary Hospital in Indonesia: A Retrospective, Single-Center Study Pulungan, Ndilalah; Thoriq, Yusa Muhammad; Hartono, Felix Giovanni; Adnan, Muhammad Luthfi; Sasetyo, Dadang Rona
Journal Orthopaedi and Traumatology Surabaya Vol. 13 No. 2 (2024): October 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v13i2.2024.61-68

Abstract

Background: Although hip fractures are common among the elderly population, there are still limited studies on neck-trochanteric fractures, one of the less common types of hip fractures. This study aims to describe the characteristics of patients and their management in patients with neck trochanteric fractures. Methods: This retrospective cross-sectional study analyzed medical records of patients aged >18 years with trochanteric fractures from a tertiary hospital in Central Java, Indonesia, between January and December 2021. Fracture types were identified and classified using the Garden, Pauwels, and AO/OTA classifications.  Demographic data, risk factors, fracture locations, and treatment types were also collected.  Statistical analysis was performed using SPSS 21.0 to describe patient characteristics. Results: The total sample was 77 patients, most were female (n = 55 (71.4%)) and aged > 60 years. More than a third of diagnosed fractures were neck of the femur fractures in 33 patients (42.9%). Among the most common classification types of fractures were Garden Type 3, Pauwels Type 3, and AO/OTA type A1.1. A total of 33 patients (42.9%) underwent open reduction of the fracture with internal fixation. Conclusions: Our findings show that the prevalence of neck-trochanteric fractures mostly occurs in patients > 60 years of age and in females. Although open reduction with internal fixation is generally performed, there are several cases of fractures that are not classifiable due to limited imaging examinations. Further research on a wider population is needed to confirm the findings of this study.
Characteristics of Patients with Thoracolumbar Fractures at Dr. M. Djamil Padang Central General Hospital in 2018-2022 Shafira, Zahra; Sahputra, Roni Eka; Noer, Mustafa; Rahmadian, Rizki; Burhan, Ida Rahmah; Irawati, Lili
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol. 14 No. 1 (2025): April 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v14i1.2025.1-9

Abstract

Background: Vertebral fracture is one of the traumas that results in the highest rates of disability and death. Vertebral fractures can occur in various regions, but more than 50% of cases occur in the thoracolumbar region T10-L2. This can be caused by several factors, such as age, gender, and BMI. More than 30% of patients have symptoms of chronic back pain accompanied by neurological deficits. This study discussed the characteristics of patients with thoracolumbar fractures at Dr. M. Djamil Padang Central General Hospital. Methods: This research is an observational descriptive study with a cross-sectional design. Research data were obtained from patient medical records, and the total inclusion sample is 139 patients with thoracolumbar fracture at Dr. M. Djamil Padang Central General Hospital in the 2018-2022 period. The data were processed and displayed as frequency distributions. Results: This research showed that the incidence of thoracolumbar fractures is found in 72 patients, with 72 being women. Mainly occurred between 15-64 years of age (73.4%), with 61.2% of cases caused by low energy trauma. As many as 62.6% of the patients received conservative management accompanied by surgery. Conclusion: This study concluded that thoracolumbar fractures often occur in women of reproductive age. The most common etiology is a fall from a height of less than three meters.
Functional Outcome of Post Anterior Cruciate Ligament Reconstruction Patients in Dr. M. Djamil Central General Hospital Padang 2020-2022 Rinaldiansyah; Rahmadian, Rizki; Fortuna, Fory; Eka Sahputra, Roni; Ramda Ilhami, Yose; Renita Rusjdi, Selfi
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol. 14 No. 1 (2025): April 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v14i1.2025.10-18

Abstract

Background: The anterior cruciate ligament (ACL) is the main stabilizer of the knee joint. The incidence of ACL injuries is quite high, especially in individuals who participate in sports. ACL injuries result in knee instability, hindering daily activities and sports participation. This study aimed to determine the functional outcomes of patients who have undergone ACL reconstruction. Methods: This study was descriptive, with a cross-sectional approach, and used medical record data from Dr. M. Djamil Central General Hospital Padang. The total sampling technique was used from patients after ACL reconstruction in 2020-2022. Patients with bilateral knee injuries, multiple ligament injuries, or revision reconstruction were excluded from the study. The samples were contacted to determine their functional outcome by filling out the Lysholm Knee Score. Results: This study analyzed 27 patients, with 77.8% in the 19-44 age group, and no patients were over 60 years old. This study identified 85.2% of male patients with sports-related injuries being the most common (70.4%). The non-dominant knee was injured more frequently (51.9%). Functional outcomes, as assessed by the Lysholm Knee Score, showed excellent, good, and moderate results in 37 %, 29.6%, and 33.3% of patients, respectively. Conclusions: ACL reconstruction was most frequently performed in the adult population aged 19–44 years, predominantly in males. Sports-related injuries were the primary cause, with the majority of reconstructions involving the non-dominant knee. The average patient achieved good functional outcomes after ACL reconstruction.
Bone Mineral Density Values Using Radiofrequency Echographic Multi-Spectrometry in Premenopausal Breast Cancer Patients Receiving Tamoxifen Therapy Russarianto, Heru; Irsyam, Ilham Abdullah; Bariqi, Muhammad Ilmam; Kadar, Pranajaya Dharma; Mohd Kamil, Muhammad Kashani
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol. 14 No. 1 (2025): April 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v14i1.2025.19-25

Abstract

Background: Breast cancer (BC) is the most prevalent malignancy in women. Tamoxifen produces varying effects on the bone according to menopausal status. This study was performed at Adam Malik Hospital to analyze the risk factors for osteoporosis, focusing on bone mineral density (BMD) and length of tamoxifen therapy in premenopausal breast cancer patients. This research also used radiofrequency echographic multi-spectrometry (REMS) to evaluate BMD as a potential alternative to dual x-ray absorptiometry (DXA) in the diagnosis of osteoporosis patients. Methods: This case-control study analyzed and interviewed 20 premenopausal breast cancer patients who received at least one year of tamoxifen therapy. The stadium of cancer, type of tamoxifen therapy, and BMD of each patient were determined using REMS. Results: The study of 20 breast cancer patients showed a mean age of 50.4 ± 5.61 years. The average length of tamoxifen therapy was 2.65 years, with a standard deviation of 1.13 years. Most patients presented with osteopenia status, namely 16 patients (80%), whereas three patients (15%) of the total sample presented with osteoporosis. REMS showed excellent accuracy in distinguishing between various tissue types, providing detailed information on tissue composition and structure. Conclusions: Based on the conducted research, it was determined that the use of tamoxifen for more than four years in premenopausal breast cancer patients influenced the incidence of osteoporosis. REMS shows potential as an alternative to DXA for the diagnosis of osteoporosis.
The Profile of Road Traffic Injury-Related Fracture Patient in the Emergency Department of H. Damanhuri Barabai General Hospital Firdaus, Muhammad Nanda; Pratista, Muhammad Bagas; Rahman, Ansari; Putera, Husna Dharma; Noor, Zairin
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol. 14 No. 1 (2025): April 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v14i1.2025.37-45

Abstract

Background: Road traffic injuries (RTIs) are a major cause of fractures, posing significant challenges for healthcare systems especially in rural areas. Based on data from to Traffic Corps of the Indonesian National Police published by the Ministry of Transportation, the number of traffic accidents in Indonesia reached 103,645 cases in 2021. Understanding the profile of RTI-related fracture patients is crucial to improve emergency care and guide preventive strategies. This study aims to identify the profile of the RTI-related fracture patient in the emergency department of H. Damanhuri Barabai General Hospital. Methods: This study was retrospective observational. We analysed the medical records of RTI-related fracture patients in Emergency Department of H. Damanhuri Barabai General Hospital during March – July 2023. We observed gender, age, mode of injury, type of fracture and bone involved. Results: There were 91 RTI-related fracture patients from 146 orthopaedic patients recorded. Male had a higher incidence (74%). The highest incidence was observed in 41 – 60 ages group (32%) and 21 - 40 ages group (31%). The most common mode of injury was double traffic injuries (65%) involving motorcycle vs motorcycle (41%). The primary type of fracture was identified as closed fracture (63%). The   bone most involved was tibia (27%). Conclusions: Fractures are common among males during their productive years as a result of traffic injuries. This study provides insights that advance understanding to the prevalence of RTI-related fractures. Additional research is required to develop further overview of RTI-related fractures.

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