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INDONESIA
Science Midwifery
ISSN : 20867689     EISSN : 27219453     DOI : -
Core Subject : Health,
Jurnal Kebidanan dan ilmu kesehatan ini adalah di terbitkan 2 kali dalam setahun, dalam bidang kebidanan dan perawat.
Articles 1,398 Documents
Effectiveness of topical combination of finasterid and minoxidil in the management of male androgenetic alopesia (systematic review and meta-analysis: Hair density study) Riyanto, Puguh; Karami, Muhammad Zuldan; Malik, Diah Adriani
Science Midwifery Vol 13 No 4 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2119

Abstract

Androgenetic alopecia (AAG) is the most common hair loss problem in men, characterized by miniaturization of hair follicles due to systemic androgens and genetic factors. AAG treatment aims to prevent follicle miniaturization Treatment modalities for AAG include hair transplantation, platelet-rich plasma (PRP), microneedling, and stem cells. Each treatment modality has its benefits and risks. The combination of topical finasteride and topical minoxidil has been shown to improve outcomes in several studies. This study aimed to evaluate the efficacy of topical finasteride compared to topical minoxidil in improving hair density among male AAG patients. A systematic literature search method was conducted using MEDLINE, Embase, AMED, Cochrane Library, Clinicaltrials.gov, Web of Knowledge, Web of Science, and WHO ICTRP with the search terms "topical finasteride and minoxidil" 'AND' "male androgenetic alopecia" 'AND' "male pattern hair loss". The literature search was carried out in accordance with the PRISMA 2009 path. Three RCTs were included in the qualitative synthesis and included in the meta-analysis. The results showed that the overall SMD in hair density was 0.751±0.215 (95% CI: 0.331 – 1.162, p<0.001) in favor of topical finasteride and topical minoxidil combination treatment, suggesting that topical finasteride and topical minoxidil combination had much greater effectiveness than control treatments in improving hair density among male patients with AAG.
Family support and medication adherence as determinants of patient decision-making in heart failure symptom management Rahmadani, Hanifa Eka; Kristinawati, Beti
Science Midwifery Vol 13 No 4 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2122

Abstract

Heart failure patients frequently experience difficulties in making decisions related to symptom management. This study aims to determine the relationship between family support and medication management behavior with heart failure patients’ decision-making in managing clinical symptoms. This study uses a quantitative approach with a cross-sectional design and involves 270 heart failure patients at a regional hospital in Central Java in 2025. The instruments used include the Family Support Scale (FSS) questionnaire, the Adherence to Refill Medication Scale (ARMS), and the Decisional Conflict Scale (DCS). The research findings indicate that the majority of respondents received good family support (69.3%), exhibited high medication management behavior (52.6%), and were confident in making decisions regarding symptom management (89.3%). Statistical analysis showed a significant positive correlation between family support and decision-making (ρ = 0.595; p = 0.000), as well as between medication management behavior and decision-making (ρ = 0.126; p = 0.039). Family support and medication management behavior have a significant positive relationship with patients' confidence in making decisions regarding the management of their clinical symptoms. It is recommended to strengthen family support and improve medication management behavior to make it easier for patients to make decisions regarding the management of their disease symptoms. Healthcare professionals should involve family members in patient education and self-care programs, while hospital policymakers can develop family-based interventions to enhance patients’ decision-making confidence.
Developing healthy food for toddlers based on local purple sweet potato food Node Siregar, Nova Sontry; Sihite, Helprida; Simamora, Mayes Felda
Science Midwifery Vol 13 No 4 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2136

Abstract

Nutritional issues in toddlers, particularly stunting, are crucial and align with the fourth point of Asta Cita (Association of Indonesians), namely improving the quality of life of the Indonesian people. This condition not only impacts children's height but also their cognitive development, productivity, and the long-term quality of human resources. To address this, innovation is needed to meet the nutritional needs of toddlers through the use of readily available and nutritious local foods. One potential local food that can be utilized is purple sweet potatoes. Purple sweet potatoes contain natural antioxidants (anthocyanins), vitamins A, C, and E, and dietary fiber, which are good for supporting growth and strengthening children's immune systems. This study aims to provide alternative local food ingredients that are highly nutritious and acceptable, readily available, and easy to process by the wider community. This study used a quasi-experimental design with a one-group pretest-posttest design on mothers of toddlers. The study variables were knowledge and skills, which were measured twice: before and after the purple sweet potato processing practice. The results showed a significant difference. (2-tailed) at knowledge 0.000 < 0.05 and skills significance value 0.000 < 0.05 then there is a significant difference between knowledge and skills before and after the purple sweet potato processing practice. The conclusion is that the purple sweet potato processing practice is effective in increasing the knowledge and skills of mothers of toddlers. The implication is that similar educational or training programs can be implemented more widely in the community to improve mothers' ability to provide nutritious food for their toddlers
Development and optimization of curcumin transfersomes in gel formulations as an antioxidant Mointi, Sella Septiyani; Kuncahyo, Ilham; Harmastuti, Nuraini
Science Midwifery Vol 13 No 4 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2139

Abstract

Curcumin, a natural compound with potent antioxidant properties, faces challenges in pharmaceutical use due to its poor water solubility and low bioavailability. To overcome these limitations, curcumin was encapsulated in a transfersome drug delivery system and subsequently incorporated into a gel to enhance topical delivery and improve drug release efficiency. This study aimed to evaluate the influence of phospholipid, Tween 80, and cholesterol ratios on the physicochemical properties of curcumin-loaded transfersomes and to assess the antioxidant activity of the optimized transfersome gel. A Simplex Lattice Design (SLD) using Design Expert software generated 14 formulations varying in the three components. Transfersomes were produced via the thin layer hydration method and analyzed for particle size, zeta potential, and entrapment efficiency (%EE). The resulting gel was characterized for pH, viscosity, spreadability, adhesiveness, diffusion behavior using Franz cells, and antioxidant activity through the DPPH assay. Statistical analyses employed ANOVA, Wilcoxon, and T-tests. The optimized formulation containing 700 mg phospholipid, 200 mg Tween 80, and 50 mg cholesterol yielded particles of 134.627 nm, zeta potential –8.924 mV, and 93.656% EE. Antioxidant evaluation showed IC₅₀ values of 24±1.78 ppm (transfersome) and 42±2.5 ppm (gel), both indicating very strong antioxidant activity. The gel released 23.12 µg/cm² curcumin within 150 minutes.
The relationship between psychological responses and pain levels in post-thyroidectomy patients at dr. Iskak General Hospital, Tulungagung Dahlia, Dina; Hidayah, Nurul; Ciptaningtyas, Maria Diah; Arif, Taufan; Subekti, Imam
Science Midwifery Vol 13 No 4 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2141

Abstract

Background: Patients undergoing thyroidectomy surgery often experience pain and psychological changes such as anxiety, stress, and depression. Objective: This study was conducted to determine the relationship between psychological responses and pain levels in post-thyroidectomy patients at Dr. Iskak Tulungagung Regional General Hospital. Methods: This study used a correlational analytic design with a cross-sectional approach. A sample of 34 patients was selected using a purposive sampling technique. Data were collected through interviews using two main instruments: the Depression Anxiety and Stress Scale (DASS) questionnaire to measure psychological responses and the Neck Pain and Disability Scale (NPADS) to measure pain levels within 24 hours after surgery. Data were analyzed using the Spearman Rank correlation test. Results: The study showed that the majority of patients experienced severe psychological responses (38.2%) and pain ranging from severe to very severe (26.5%). Statistical tests showed a very strong and significant relationship between psychological responses and pain levels (r = 0.959; p = 0.000). Conclusion: This study contributes to strengthening the biopsychosocial approach in perioperative nursing. Practical implications suggest that psychosocial interventions should be integrated into postoperative pain management.
The relationship between diet and the risk of diabetes mellitus in elementary school children grades 4-6 at Sdn Tasikmadu 1 Malang Oktafiani, Khoirun Nisa; Astuti, Erlina Suci
Science Midwifery Vol 13 No 4 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2142

Abstract

The prevalence of Diabetes Mellitus (DM) among children in Indonesia has shown a significant increase in recent years. The rise in type 2 diabetes is influenced not only by genetic factors but also by unhealthy lifestyles, particularly poor dietary habits. This study aimed to examine the relationship between diet and the risk of diabetes mellitus among elementary school students in grades 4–6 at SDN Tasikmadu 1 Malang. This quantitative research used a cross-sectional design and was conducted in May 2025, involving a sample of 100 students. Data were analyzed using the Chi-square test. The results showed that among children with unhealthy diets, 27 students (46.6%) had a high risk of diabetes, while among those with moderate diets, 18 students (42.9%) had a low risk. Statistical tests showed a significant association between dietary patterns and diabetes risk (χ² = 7.544; p = 0.023), with a linear-by-linear association (χ² = 7.135; p = 0.008). These findings indicate that the less healthy a child’s diet is, the higher their risk of developing early symptoms of diabetes. In conclusion, there is a significant relationship between dietary patterns and the risk of Diabetes Mellitus among elementary school children.
Addition of black pepper extract as an antibacterial in the manufacture of polyvinyl alcohol (PVA) and carboxymethyl cellulose (CMC) based hydrogel wound dressings Yani, Septi Nanda; Hadiah, Fitri; Sari, Tuti Indah
Science Midwifery Vol 13 No 4 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2143

Abstract

This study aims to determine the effect of adding black pepper (Piper nigrum L.) extract on the characteristics of a hydrogel wound dressing made from a mixture of Polyvinyl Alcohol (PVA) and Carboxymethyl Cellulose (CMC), and citric acid as a crosslinking agent. The manufacturing process was carried out by chemical crosslinking with varying concentrations of CMC (5%, 7.5%, 10% w/v) and black pepper extract (0%, 10%, 20%, 30%, 40% v/v). The analysis included FTIR, SEM, swelling degree, water solubility, tensile strength, and antibacterial activity against Staphylococcus aureus. The results showed that the addition of black pepper extract increased antibacterial activity and water absorption (swelling) up to 200–500%, in accordance with the standards for good wound dressings. However, increasing the concentration of black pepper extract tended to decrease water solubility due to its hydrophobic nature. Overall, the PVA/CMC hydrogel with the addition of black pepper extract showed potential as a biocompatible wound dressing with good mechanical properties and antibacterial activity. The gel released 23.12µg/cm²curcumin within 150 minutes.
The relationship between physical activity and the risk of diabetes mellitus in elementary school children (ages 8–12 years) Bimantari, Rafina; Astuti, Erlina Suci
Science Midwifery Vol 13 No 4 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2146

Abstract

The rapid advancement of technology and shifts in modern lifestyles have led young children to spend more time indoors engaging with electronic devices, consequently reducing their physical activity levels. Insufficient physical activity during early childhood is considered a potential risk factor for developing Diabetes Mellitus (DM). This study aimed to investigate the relationship between physical activity and the risk of DM among elementary school children aged 8–12 years. A cross-sectional quantitative design was employed in May 2025 at SDN Tasikmadu 1 Malang, involving 154 participants within the specified age range. Data were analyzed using the Chi-Square test. The results indicated that 84.4% of the children demonstrated a moderate level of physical activity, while 15.6% exhibited a high level. Regarding diabetes risk, 43.5% were classified as moderate risk, 37.0% as low risk, and 19.5% as high risk. Statistical analysis revealed no significant association between physical activity and diabetes risk (p = 0.294, p > 0.05). In conclusion, there was no statistically significant relationship between physical activity and DM risk among the studied population. Nevertheless, regular monitoring and the promotion of physical activity remain essential to support overall child health and reduce the likelihood of future metabolic disorders.

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