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Indian Journal of Forensic Medicine & Toxicology
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Core Subject : Health,
Articles 5,497 Documents
CA 27-29: A Valuable Marker for Breast Cancer Management in Correlation with CA 15-3 Hiba Sarmad Kamal AL-Azzawi1 , Manal Kamal Rasheed2 , Manwar AL-Naqqash3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11773

Abstract

Background: Breast cancer is the most common invasive cancer in women, and second main cause ofcancer death in women after lung cancer. Tumor markers that showed evidence of clinical utility and wererecommended for use in practice include CA15-3, CA27-29 and Carcinoembryonic.Aim of the study: This study was designated to measure the levels of CA15-3, CA27-29 and CEA andevaluate their clinical significance in metastasis and non- metastasis patients with breast carcinoma,comparing their sensitivity and specificity.Patients, Materials and Methods: Serum levels of (CA27-29) and (CA15-3) were measured in 62 patients(40 in non-metastasis and 22 in metastasis patients). The age of patients was from (30 to 90) years old.Samples were collected from the Oncology Teaching Hospital in Baghdad Medical City.Results: The levels of CA15-3, CEA were significantly higher in metastasis group compare to non-metastasisgroup. while the levels of CA27-29 were no statically significant difference between the two groups.Conclusion: In this study, measurement of CA15-3 and CEA correlated with disease activity especiallyin the metastatic setting. on the contrary, CA27-29 did not show such clear correlation. CA15-3 was moresensitive in follow up of breast cancer patients followed by CEA and then CA27-29.
Incidence of Mumps in Anbar province, West of Iraq during the Period 2009-2018 Mothana Ali Khalil1 , Hekmat Ahmed Owaid2 , Shehab Ahmed Lafi3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11774

Abstract

Background: Mumps (infectious parotid gland) is an infectious viral disease mainly affects children andadolescents characterized by enlargement of parotid and salivary glands, other epithelial tissues may beaffected, in some cases it is accompanied by serious complications. In recent years many mumps cases inAnbar province have appeared in people who have been vaccinated with Mumps vaccine and for reasonsthat are not clearObjective: To Show the annual mumps incidence with age groups and sex for those affected in AnbarprovinceMethods: A Descriptive cross-sectional study of the electronic archives of mumps patients who wereimmediately registered in Anbar Governorate hospitals, during the period from 2009 to 2018. Thequestionnaires regarding year of infection, gender, and age of mumps patients included in the study. Mumpsincidence has been calculated through dividing the number of annual cases of infection by population sizemultiplied by 100,000. SPSS software version 24 were used for data analysis.Results: Of 2924 Mumps patients registered at Anbar province hospitals, 1715 (58.7%) were males with 12.1± 4 years mean age . The incidence rates of Mumps in 2009, 2010, 2011, 2012, 2013, 2014, 2015,2016,2017& 2018 were (0.50, 0.20, 0.70, 0.80, 1.70, 0.00, 0.00, 7.20, 97.90& 59.00) / 100,000 respectively withstatistically variance among males & females; p value = 0.000 & annual incidence ratio was 21.00 / 100,000.Annual Mumps incidence ratio from 2009-2018 confirmed one peak in 2017-2018 & a rare 2009-2016,Majority of them were in the age group 5 to14 years old.Conclusion: Mumps incidence had been increase during the last 2 years mainly in the age group 5 to14years old with a marked increase incidence in male in Anbar province, Iraq
Effect of Insecticide “Maxxthor” on Some Hematological and Oxidative Stress Parameters in Male Albino Rats Entesar A. Essa1 , Layla J. Mohammed2 , Jabbar H. Yenzeel3 , Sahar A. H. AL-Sharqi4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11776

Abstract

The present study was designed to investigate the effect of different concentrations of Maxxthor on somehematological and oxidative stress parameters in male albino rats.Twenty male rats with age of 6-8 weeks andweight of 200-250gm were equally divided into four groups as follow:G1 treated with normal saline as controlgroup,while G2,G3andG4groups were treated with(0.01,0.1,1)mg\kg body weight of Maxxthor respectivelyfor 40 days.The following hematological parameters were measured: red blood cell(RBC),hemoglobin(Hb),white blood cell(WBC), platelets(PLT),malondialdehyde(MDA),glutathione(GSH),catalase andvitamin E. The hematological parameters results revealed highly significant(p<0.01)decreasein RBC andH,while a highly significant(p<0.01)increase in WBC and PLT in all treated groups as compared with control.The oxidative stress parameters results revealed highly significant(p<0.01)increase in MDA level,whilehighly significant(p<0.01)decrease in GSH,catalase and vitamin E level were noticed in all treated groupsas compared with control .
Using Probiotics, Antibiotics and their Combinations to Eradicate Biofilms Formed by Four Pathogenic Klebsiella Pneumoniae Strains Omer N. Abbas1 , Abdulwahid B. Al-Shaibani2,3, Ahmed A. Mhawesh2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11777

Abstract

Klebsiella pneumoniae is an opportunistic pathogen leading to nosocomial infections with production ofbiofilm. In the present study, 73 samples were collected from patients of different ages and both genderssuffering from burn and wound injury that referred to four Hospitals in Baghdad from Aug. to Nov. 2019.All Klebsiella isolates were subjected to the primary identification; first by describing colonies grown onMacConkey agar and second microscopically after Gram staining of their cells. Then the isolates wereidentified by Vitek 2 system which insured that 60 of the isolates were found to belong to Klebsiellapneumoniae. All identified isolates were screened for ability to produce biofilm by using the Microtiterplate assay and the Congo red agar method, and the results showed that only 4 isolates (3 of wounds and1of burns) were able to form biofilms. For the importance of these four isolates as the only ones able toproduce biofilm, they were subjected to the 16S rRNA gene amplification test by using PCR technique.Results insured that they are new strains Klebsiella pneumoniae to be discovered for the first time in thisstudy. They were verified and documented by the “National Center for Biotechnology Information (NCBI)”and registered as; KPWIQ25, KPWIQ49, KPWIQ51 and KPBIQ19 strains of Klebsiella pneumoniae. Whenthe probiotic filtrates and antibiotics combination were investigated for eradication of biofilms formed bythe four pathogenic strains, results showed that such combinations had great efficiency in the eradication.
Study and Assess the Occupation Hazards to Health Workers in the City of Kut/ Wassit Fatima Haran Daham1 , Alaa Kadhim Jasim 2 , Khalied Yassen Zakair3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11778

Abstract

Background: Occupational hazards are a major medical, social, economic problem and a leading cause ofmorbidity and mortality for health workers. The aims of this study was to identify the types of occupationalhazards and risks that health workers are exposed to in the study area. In addition, to measure risk level ofoccupation hazards. This is a cross sectional descriptive study was carried out among health workers in twohospitals located in Kut city in Wasit governorate. The period of the study extended from October 2019, untilthe end of March 2020. Data collected by using questionnaire form. The occupation hazards dimensions,which include four domains: physical hazards, chemical hazards, biological hazards, and psychologicalhazards. The statistical methods used included Chi-square and Fisher exact test. A statistical significantassociation (p<0.05). The main findings of the current study indicate that the commonest occupationalhazards among the health workers in Al- Kut hospital was noise (58.6%), and the second hazard in thiscategory was fire (51.9%). While in Al-Karamah hospital the commonest occupational hazards among thehealth workers was noise (57.9%) . Conlusively, the study was found that health workers in Al-Karamahhospital had experienced light, heat, noise, psychological, and chemical hazard higher than health workersin Al-Kut hospital. In addition , the health workers in Al-Karamah hospital had experienced biological lowerthan health workers in Al-Kut hospital.
Associated Factors of Adulthood Overweight/Obesity among Pharmacy Department Students in Al-Rafidain university College / Iraq Samer Shukur Mohammed1 , Wael Waleed Mustafa2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11779

Abstract

Youth people overweight or obesity has become a main public health concern globally because of itsadversarial health outcome and escalating prevalence. The aspects of disease conditions demonstrated duringearly older life commonly originate in youth stage of life. Iraq after wars is went through a transition wherethey started to go under-nutrition and co- exists with obesity. even though, there is a lack in documentedinformation on college life and being overweight or obesity in Iraq. our study was carried out to documentedfor the first time the prevalence and associated factors of adulthood overweight or obesity among pharmacydepartment student in Alrafidain university college. Data were collected using a structured self-administeredquestionnaire from February 2019 to December 2019in grades 1–5 students of pharmacy department inAlrafidain university collegeHeight and weight measurements of 300 students were taken and BMI- for-age-sex was calculated usingWHO AnthroPlus. Based on that, participants were divided to three groups as normal weight (BMI 20–25),overweight (BMI 26.0–30), and obese (BMI > 31.0).Participates response rate is 81%. Age of students take a part in the current study was 21.43 ± 3.81 years. Thecategory of students were 96 students (32%) overweight student 90(30%). The significant different P<0.05among groups were found of particular questions included eating outside their home.
Serological, Culture and Urea Breath Test for Detection of H. Pylori in Gastric Ulcers Patients Nktel Faaz AL-Saad1 , Nadhim M.H2 , Nawar H.Y2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11781

Abstract

Helicobacter pylori t is the causative agent of duodenal ulcers and gastric ulcers, thus, it is very importantto determine the most appropriate system used to diagnose it. The current study use invasive and noninvasive process for diagnosis of H. pylori. Culture of H. pylori is one of these invasive systems, and theresults revealed that 35% of specimen was culture positive ( 62.5% in male and 37.5 in female) While, thenon-invasive method like UBT and ELISA IgG and IgA show 67.1% and 71.5% , 29.2% positive resultsrespectively. The distribution of positive test results between male and female by UBT was (41.3%) maleand (58.7%) female) while, the distribution of positive test results between male and female by ELISA IgGand IgA were (61.4%) , (26.3%) in male patients and (78.75%) , (31.25%) in female patients respectively.The results of UBT were increase with age, (34 positive patients in age group 51-60 years old). Serologicaltest of ELISA IgG shows that great % of H. pylori infection (74%) found in patients with group age (41-50)yr.O. and the lowest percentage (39%) was found with age group (< 20 ) years old while, percentages ofpositive cases of ELISA IgA in young age below 20 years old was 79% related to low % with ages increase.
Low Pollution Emission to Purify Fuel Cell Technology Comprehensively: A Review Muhaned Mohammed Eteya1 , Hayder Saleh Mahdi2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11782

Abstract

In recent decades, scientists have been urged to build the new energy resources by depleting fossil fuel,high-energy demand and pollution. Being one of the principal alternative power devices, Thanks to thehigh energy conversion efficiency, the fuel cells have attracted growing attention, simple operation andlow pollution emissions. This paper surveys the historical backdrop of the power devices, the energy unitactivity, and sorts of energy units, their points of interest, inconveniences and applications.
Major Histocompatibility Complex gene Polymorphism in Systemic Lupus Erythematosus Patients Zahraa Haleem Alqaim1 , Methak J. Al-Jboori2 , Mona N. Al-Terehi3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11783

Abstract

The major histocompatibility complex (MIC) is one of the MHC class I related genes which related withautoimmune diseases , the present study aims to investigated association between MIC gene polymorphismclass I in systematic lupus erythrymatous patients within Hilla city, the present study implemented usingwhole blood genomic DNA and single strand DNA conformation polymorphism (SSCP) for detection genepolymorphisms and haplotypes frequency, The results of present study show that 183 bp of MIC gene and ithas three haplotypes (A, B, and C) each of these haplotypes consist of two bands, non-significant differencesbetween patient and control in haplotypes frequency, B haplotype was more frequent in patinas than others(20%) while A was more frequents in control than others (22.8%). The present study concluded that MICgene may be contributed in immune response of SLE and can be used in pre diagnosis of disease. This studywas one of the serious investigators deal with several immune genes in this disease in Iraqi SLE.
Deleted Alaa Abd Kadim1 , Suha Hussein Mohammed1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11784

Abstract

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