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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
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Development and Preparation of ciprofloxacin Drug Derivatives for Treatment of Microbial Contamination in Hospitals and Environment Aseel Mahmood Jawad1, Nagham Mahmood Aljamali2, Saher Mahmood Jwad3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3067

Abstract

This practical studying involved preparation and development of new medical derivatives of ciprofloxacin drug via series of chemical reactions to preparation new derivatives to resist types of bacteria in hospitals and environment.Various chemical routes have been used to prepare ciprofloxacin derivatives ,then all these derivatives reconnoitered with many spectral chemical techniques for instance (FT.IR ,H.NMR ,C.NMR )– spectrophotometric ,then studying of their effects on bacterial pollution.
Comparison of Surgical Outcomes between Patients Treated with The Harmonic Scalpel and Ligasure Device During Total/ Near Total Open Thyroidectomy Aseel Mahmood Jawad
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3068

Abstract

Over the last few years many surgeons have begun to utilize the LigaSure device or Harmonic scalpel to perform thyroid surgery. Several papers have demonstrated the benefits of these devices over traditional hand-tying techniques. The purpose of this study was to examine our institution’s experience with the LigaSure device and Harmonic scalpel during thyroid surgery and to compare mean operative times and complications associated with each device.The aim of the study was to compare surgical time,postoperative complications and other parameters between ligasure device and harmonic scalpel in the open thyroidectomy procedure. We choose to examine our institution’s experience with the LigaSure and Harmonic scalpel during total/near total thyroidectomy
Safe Concentration of Benzene Exposure Based on Safe Human Dose of Workers in The Paint Manufacturing Industry Sidoarjo, East Java, Indonesia Ayu Prima Kartika1, Vivi Budiarti1, Achmat Kuncoro1, Charles Kimura1, Abdul Rohim Tualeka2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3069

Abstract

Background: Manufacture of paints using benzene in large quantities in the products they produce. Workers in the paint industry may face an increased risk of high health complications. The purpose of this study was to determine the levels of safe concentration of benzene for workers in the Paint Manufacturing Industry in Sidoarjo East Java, Indonesia. Methods: This research was conducted using a cross sectional method. The sample in this study were 24 respondents. The variables that became the data of this study included benzene concentration (C) time of daily exposure (tE), frequency of annual exposure (fE), duration of exposure (Dt), height (cm), weight (kg), age, respiration rate (BR), body surface area, weight of white rat, body surface of white rat, highest dose of toxin without effect on experimental animals (NOAEL), Km factor in animal (Animal Km), Km factor on workers (Human Km), safe limits for toxin doses for workers (SHD), and benzene concentrations in safe air for workers (C is safe). Data analysis in this study was carried out by using quantitative data analysis manually to determine the safe concentration of benzene for workers in the Paint Manufacturing Industry in Sidoarjo East Java, Indonesia. Results: Based on the results of measurements carried out, the concentration of benzene in the work environment of the Sidoarjo Paint Industry in the mixing solvent section is 2 ppm and in the packing section is 0.4 ppm, the safe concentration is 0.028 ppm. Conclusion: The recommended safe concentration of benzene exposure is 0.028 ppm. The safe concentration value exceeds the set value of 0.009 ppm daily for acute effects and 0.003 ppm daily for chronic effects, so control measures are needed to protect against the adverse effects of benzene on the health of workers. Control recommendations are to provide a good exhaust ventilation system at the paint manufacturing.
Determination of the Health Costs of Effective Detoxification Based on Effective Doses of Benzene Exposure To workers in oil and gas mining companies, Central Java, Indonesia Ayu Prima Kartika1, Vivi Budiarti1, Achmat Kuncoro1, Charles Kimura1, Abdul Rohim Tualeka2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3070

Abstract

Benzene is a natural component of crude oil and gasoline. Benzene occurs naturally in crude oil at levels of up to 4 g / l and benzene has been classified as a group carcinogen. This research was conducted in oil and gas mining companies, West Java, Indonesia. This research was conducted using a cross sectional method. The sample in this study were 30 respondents. The variables that became the data of this study included benzene concentration (C) daily exposure time (tE), frequency of annual exposure (fE), duration of exposure (Dt), height, weight, age, respiration rate (BR), and urine of workers. The results showed an average measurement of benzene concentration in oil and gas mining companies, West Java, Indonesia on the KPC portion of 0.1 ppm and in the laboratory section at 0.2 ppm, which means it is still below the Threshold Value (NAB) which is equal to 0.5 ppm5. Obtained the highest effective dose to be consumed by respondents in the KPC unit for beef liver is 6x10-4 kg at a cost of IDR 33,31046813, chicken 3x10-4 kg at a cost of IDR 13,1251,9985, and avocado is 4x10-6 kg at a cost of IDR 0,16206628 , while the highest effective dose to be consumed by respondents in the laboratory unit for beef liver is 1x10-2 kg at a cost of IDR 12,14687477, chicken 6x10-4 kg at a cost of IDR 22,14504841, and avocado is 6x10-6 kg at a cost of IDR 0, 27344083. Control recommendations are to adopt a lifestyle that can minimize exposure to poisons and improve detoxification pathways.
Relationship of Hot Work Climate with Employee Blood Pressure in Binat Installation, Dr. Sardjito Charles Kimura1,Ledita Sartika Goddess2, Zikri Fathur Rahman1, Abdul Rohim Tualeka1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3071

Abstract

Blood pressure in each individual varies, and depends on age and daily activities such as when blood pressure activity will rise and when the remaining blood pressure will drop. Laundry installations are workplaces where there is a physical hazard in the work process in the form of a hot working climate. In a hot working climate, the body regulates its temperature by accelerating the evaporation of sweat by widening (vasodilation) of blood vessels which results in increased blood circulation and increased capillaries accompanied by physiological responses, such as increased pulse and blood pressure. This study aims to analyze the relationship between the work of heat and blood pressure of workers in the Laundry Installation of RSUP Dr. Sardjito Yogyakarta. This study uses quantitative research design using a cross sectional approach. The population in this study were Laundry Installation workers with a sample of 35 respondents taken with total sampling. Data analysis using Chi-Square. The results showed that there was a relationship between the hot work climate and workers’ blood pressure (p = 0.03) and there was a relationship between the hot working climate and diastolic blood pressure of workers in the Laundry in RSUP Installation. Sardjito Yogyakarta (p = 0.01).
Analysis of Worker’s Level of Knowledge on Handling Chemicals in Oil and Gas Industry Laboratory of Pt “X” Indonesia Dani Nasirul Haqi1, Putri Ayuni Alayyannur1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3072

Abstract

The oil and gas industry is one of a large-scale industry, which is when carrying out the production process, they contain several hazard posed that can threaten labor, assets, and other people in industrial environment such as chemical hazards. The chemical groups have special characteristics in disturbing and threatening labor. Knowledge is one of the important factors in preventing work accidents and work-related diseases due to chemicals. This study is a descriptive study, and the data was collected by observational. The object of research in this study is knowledge of workers on handling chemicals. The sample is a total population of 28 workers. The results of the research obtained were that most workers already had adequate knowledge regarding handling chemicals in the laboratory. The highest concentration of chemicals in the laboratory is Benzene (19.1 ppm), Toluene (30.56 ppm) and Xylene (20.48 ppm). The conclusion of this study is that knowledge is a very important domain for the formation of a person’s behavior. In this case, it is related to the handling of chemicals found in the laboratory. If the level of knowledge of the workers is high, the handling of chemicals in the workplace can be carried out maximally, so that workplace accidents can be prevented and the safety of workers can be maintained.
Climate Relationship Work with Fatigue Employees Working in Laundry Plant Dr. Sardjito Dyah Ayu Kusuman Ningrum1, Anggita Kurniawati2, Abdul Rohim Tualeka1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3073

Abstract

Laundry Installation is one of 29 installations in Hospital Dr. Sardjito. Laundry instalation has 35 employees who have worked with exposure to high temperatures up to 35?C. The hot working climate be the cause of fatigue on employees. The purpose of this study was to Determine the relationship between the work climate in employees with work fatigue Hospital Dr. Laundry Installation Sardjito Yogyakata. The study design used is cross sectional. The population in this study as many as 35 people. The sampling technique used is total sampling the entire population of employees that numbered 35 people. The results of the study with the statistical tests Man Whitney p value 0.022 Obtained value <0.05 the which means that Ho refused so that there is work climate relationship with work fatigue of employees working in the department of Dr. Laundry Installation Sardjito. The advice given to the installation related to that with the addition of Appropriate ventilation in the standard installation space doing laundry and job rotation system working parts so that employees do not feel monotonous with the work performed.
Association of Noise Exposure and Physical Workload on Systolic Blood Pressure of Ceramic Industry Workers Erike Anisa Nurshafa1, Noeroel Widajati1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3074

Abstract

Noise is a major problem in modern industrial activities. The use of machines in industry and inseparable design of work between humans and machines makes workers exposed to noise as one of the physical hazards in the work environment. Noise can cause physiological reactions such as systolic and diastolic blood pressure disorders. However, systolic blood pressure response is more sensitive to changes. The systolic pressure after loading is normally up (20 mmHg), the rest is considered abnormal and is considered one of the risk factors for cardiovascular disease. Blood pressure is a multifactorial health indicator. In addition to noise, blood pressure is also influenced by the physical workload that workers receive as one of the factors of workload. The purpose of this study is to examine the relationship of noise and physical workload to an increase in systolic blood pressure. This is a cross sectional design and observational analytical study with statistical tests using spearman. Respondents were determined through simple random sampling technique that results in a sample of 36 ceramics industry workers in the production line section. The results showed the value of the noise relationship (r = 0.581) towards the increase in systolic blood pressure. Physical workload showed a relationship value of (r = 0.666) towards the increase in systolic blood pressure. The direction of the relationship between the independent variable and the dependent variable is positive, which means that the higher the noise level and physical workload, the higher the risk of abnormal systolic blood pressure.
Determination of Oxidant / Antioxidant Levels in Sheep with Hydatite Cyst in Liver Evan Abdul Kareem Mahmood1, Mert Handan2, Mert Nihat2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3075

Abstract

The larval form of Echinococcus granulosus, hydatid cyst is an important parasitic zoonosis commonly seen in animals and humans. The aim of this study was to investigate the efficacy of oxidative stress on the pathogenesis of cystic echinococcosis with antioxidant / oxidant status in sheep sera. The material of the study was composed of sheep infected with hydatid cyst and healthy cut in slaughterhouse in Van province. The general health status of the sheep before slaughtering was checked by physical examination and blood samples were taken. After slaughtering, cyst hydatid examination was performed in different organs of the animals. The control group consisted of 25 sheep study cases with positive (fertil cyst) and 15 sheep without any pathological lesion on organ examinations and healthy on physical examination. Blood samples taken from animals infected with healthy and hydatid cysts were transported to the laboratory under appropriate conditions and centrifuged. Total antioxidant / oxidant status, paraoxonase and arylesterase activities were measured by using commercial kits. Compared with cystic echinococcosis group and healthy group, the importance was calculated on the TAS, PON1 activities (P <0.01), TOS, ARES activities differences (P <0.001), It decreases. This may cause tissue necrosis and increased inflammation . Decrease in antioxidant reserves; excessive free radical formation in the ewes with cystic echinococcosis causes deterioration of the normal histological structure of the organ in the cyst.
Assessment of Health-Related Quality of Life Among Patients Management Program of Chronic Diseases Type 2 Diabetes Mellitus Fajriansyah1,2, Iskandarsyah A3, IM Puspitasari1,4, Keri Lestari1,4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3076

Abstract

Type 2 Diabetes Mellitus (T2DM) has significant adverse effects on health-related quality of life. PROLANIS program is a system of governance of health services and health education for social health insurance participants who suffer from type 2 diabetes mellitus to achieve the optimal quality of life independently. This research aims to measure quality of life in T2DM patient. The research was an analytical non-experimental study according to the patient’s perspective using prospective data collection techniques. The subjects are PROLANIS patient T2DM who comply inclusion and exclusion criteria.The data were collected by using the European Quality of Life 5 Dimensions 5 Levels (EQ-5D-5L) Indonesian questionnaire. Data analysis using EQ-5D preference weight for each health state using Indonesian EQ-5D-5L Value Set. Furthermore, the percentage of the patients’ problems, EQ-5D index (utility) and EQ-5D VAS were calculated. A total of 220 patients were included. Seventy-two different EQ-5D index values were described by the patients. Obtained 37 subjects (16.82%) had no problems. The EQ-5D index value highest is 1,000 (n = 32, 14,54%) and EQ-5D index value lowest is -0,384 (n = 1, 0,45%). EQ-5D index value has an average is 0.57 (SD 0,32) and EQ VAS value has an average is 72.19 (SD 14.73). This study also confirmed that T2DM remains a critical predictor of health outcomes among patients. Results from this study could be constructive in clinical practice, particularly in the early treatment of T2DM patients where improving HRQoL is still possible.

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