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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 488   489   490   491   492 
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Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15577

Abstract

O
Bacterial Co-infections and Antibacterial therapy in retrospective COVID-19 patients in AL Fallujah General Teaching Hospital AL-Karbolii M. M
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15578

Abstract

In order to determine a retrospective study data were collected from all 2031 COVID-19 patients detected by PCR (nasal swap) from January/ 2020- January /2021 for Fallujah General Teaching Hospital ,which total number of Positive covid19 were 210 in isolation ward and Negative number of COVID-19 were 1821.The study condense on bacterial co-infections and antibacterial therapy for this bacteria. Clinical information were : the genera females were 60 ( 28.5%) and were males 150 (71.4%). microbiological detected isolation from blood sample through 48hour of 210 COVID-19 patients in isolation ward detected by BACT/ALERT® Culture Media(1)then cultured on routine bacteriological media according to(2)for positive growth isolated bacteria then identification were done by biochemical test. The result of bacterial isolation from blood of patients assumptive co-infections among 210 samples, positive growth isolated of bacteria which were 121 (57,6%) and included S. pneumoniae , S. aureus , S. epidermidis, K. pneumoniae, p. aeroginosa and E. coli and total negative isolated which indeed enclose 89 (42.3%). Depending on ABS achieve guidelines, the most commonly used antibiotic way was Meropenem, Azithromycin and Cefixime with a median duration of 6 (range 1–13) days in isolation ward and when using Antibiotic Susceptibility test expressed each resistant and sensitive bacteria to antibiotic discs for all positive isolate and detected by sensitivity patterns of VITEK2 system to some species as ensuring method, but; the study focus on co-infection had the highest frequency of Staphylococcus aureus 57 (47.1%) isolates which were resistant to Ciprofloxacin, Chloramphenicol, Gentamycin, Amikacin, azithromycin, Cefotaxime, tetracycline ,Trimethoprim/ Sulphamethoxazole and sensitive to Levofloxacin and imipenem.
Analysis of MCL-1 Copy Number Variation in Non-Small Cell Lung Cancer Almahdi Alzaroukh Jaber; Howard Pringle; David Guttery; Aesa Alzaroug Jaber
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15579

Abstract

Amplification of the MCL-1 gene induces MCL-1 overexpression, which is an important marker for drug resistance in several malignancies through evasion of apoptosis. We analysed 39 lung adenocarcinomas (ADCs), 38 lung squamous cell carcinomas (SCCs), two large cell lung carcinomas (LCCs) and cell lines. A duplex ratio test TaqMan qPCR approach was performed for MCL-1 copy number change analysis and we demonstrated amplification of MCL-1 in H1395 cell line and copy number gain (isochromosome) in H2342 cell line. Immunohistochemistry (IHC) and in situ hybridization (ISH) were performed for protein and mRNA analysis respectively. MCL-1 amplification was detected in 13% and 2.5% of SCCs and ADCs respectively. MCL-1-amplified tumours demonstrated high expression of MCL-1 mRNA. Copy number gain was detected in 2.5 % of ADC but not SCC.
Effectiveness of an Educational Program Directing toward the Domestic Violence Behavior among Secondary School Students Amena Razzaq Jasim; Arkan Bahlol Naji
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15580

Abstract

Background: Domestic violence is now considered as a global health issue. It is defined as a threat or physical, psychological and/or emotionally violent act. Methods: An experimental design was used to guide this study. The study was conducted at three secondary schools for girls from Al-Mahmudiya district. The study included a sample of 200) secondary school student girls who were randomly selected. The education program is implemented through three sessions. Each session is scheduled for 45-minutes.Study instrument: A questionnaire was adopted from Elabani (2015). The behaviors considered as domestic violence against women scale was used to measure behaviors that women consider them implying domestic violence against them. The study results revealed that was a (a priori p = 0.01) significant difference in the domestic violence as a behavior over time for participants in the study group. The omnibus effect (measure of association) for this analysis is .883, which indicates that approximately 88% of the total variance in the domestic violence as a behavior values is accounted for by the variance in the administered intervention.Conclusion : The implemented program positively affected the values of the domestic violence as a behavior, for the study group by time compared to the control group.
Molecular Association of Sexually Transmitted Infections and Methylation Pattern of SNRPN Gene Promoter among Males with Abnormal Semen Noor AL-Hamid; Abdul Kareem AL-Kazaz
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15581

Abstract

Infertility affects about 8-12% of couples worldwide, and male infertility accounts for a half of these cases, therefore, thisstudy was undertaken to focus on some factors affecting male’s fertility such as DNA methylation and genital tract infections by sexually transmitted diseases. The study groups included infertile males as a patient group (n=63) in an age mean (32.28 ± 6.88 years) and fertile males as a control group (n=13)in an age mean (34.07 ±6.52years).Seminal fluid was collected from all males attending a clinical laboratory for routine semen analysis, seminal fluid analysis was performed according to World Health Organization guidelines, all of the 63 infertile males was suffering from reduced sperm concentration (9.42 ± 8.70 million/ml), reduced progressive motility (2.89 ± 5.45%) and abnormal sperm morphology (27.06 ± 16.50%), while control group have a higher values thus, there was a highly significant difference in semen parameters between the two groups.The DNA samples of the patients group (n=44) and control group (n=13) was subjected to bisulfite treatment to convert un-methylated C-residues to uracil, this step was performed to allow the qualitative detection of methylation at the promoter of Small nuclear ribonucleoprotein polypeptide N gene by Real time polymerase chain reaction using two sets of designed primers (methylated and un-methylated sets) allowing one set of the primers to anneal, and amplify the desired region.The results of real time PCR for the detection of methylation in SNRPN gene promoter showed hyper methylation in the promoter of SNRPN in some samples (22.7%), a slight methylation in others (20.4%) and no methylation in other samples (56.8%) from infertile males, while all the 13 control samples showed no methylation.
Obturation Quality of Chitosan-Modified Glass Ionomer Cement in Root Canals (In Vitro Study) Abdulkareem R. Al-Mezouri; Hussain F. Al-Huwaizi; Dara H. Saeed
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15582

Abstract

Background: Many materials are used for root canal obturation but all of them possess certain drawbacks. In the present study compared the obturation quality of Glass ionomer cement containing chitosan root canal filling material with other regularly used materials by using dye penetration. Material and Methods: Thirty-six human roots were chosen for this study. After de-coronation of the teeth and separation of the desired roots, they were instrumented by the Protaper Universal system from S1-F4 and then divided into three major groups: Group 1, filled with experimental material (glass ionomer cement/Chitosan); group 2, filled with gutta-percha with zinc oxide eugenol sealer; group 3, filled with gutta-percha with AH26. The evaluation was performed by radiographs post-obturation and by dye leakage test.Results: There was no significant difference between root canal obturation materials.Conclusions: The use of glass ionomer cement with chitosan root canal filling material improves the obturation quality of root canals.
Aspirin Resistance in Patients with Chronic Coronary Syndrome A.L.Alyavi; Sh.I.Khodjanova; J.K.Uzokov; Sh.Kadirova
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15583

Abstract

This review summarizes aspirin features, actions and resistance in patients with chronic coronary syndrome. As well, it describes mechanism of the aspirin action and possible ways and causality of the aspirin resistance. In addition, it shows how to assess the efficacy of the aspirin therapy in patients with chronic coronary syndrome.
Effect of Methanolic Extract of Green Algal Enteromorpha Intestanalis on the Bioactivity of Giardia lamblia Parasite Abdul Wahab Raisan Ayal
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15584

Abstract

The present study was conducted to detect the effect of Enteromorpha intestanalis methanol extract and study of its therapeutic effect in male Mus musculus experimentally infected with Giardia lamblia parasite, The mice infected with the parasite were dosed with the aforementioned extract at a concentration of (2, 2.5, 3) mg / ml at a dose rate per day for 25, 20, 15) days, and examining the faeces of the mice to monitor the change in the parasite preparation after the extract with the extract, and the results showed that the extract of the moss was Effective in reducing the numbers of encapsulated and feeding phases in mice infected with the parasite. The highest rate of killing of the feeding and encapsulated phases was recorded at a dose of (3) mg / ml during the twenty-five days’ period. Specific disclosures were made of chemicals for secondary metabolism of the algae extract, which indicated the presence of chemically effective compounds such as alkaloids, phenols, flavonoids, cyclosides, turpenoids, tannins, soaps and carotenoids. During the experiment, the therapeutic efficacy of the extract was calculated (64.30%). The chemical compounds of the algae extract were diagnosed using the Gas chromatography mass spectroscopy (Gc-mass) technique.
Determination of Vitamin D Concentration in Diabetic and Non Diabetic Men and Its Correlation with Age Abdulhadi M. Jumaa; Meqdam Atiyah Khalaf; Hassan Yashar Hassan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15585

Abstract

Background Vitamin D is synthesized from precursors” present at the surface of the epidermis and then undergo biotransformation which achieved at the hepatocytes and finally by hydroxylation enzymes in the nephrons “ . “sunrays play a crucial role in the beginning of D vitamin formation processes, parathyroid hormone is an essential hormone secreted by parathyroid glands and play a key role in the activation of D vitamin by renal alfa hydroxylase”. Food sources of D vitamin are also important for supplementation of human body with some requirements. This Study Aimed to compare the concentration of vitamin D in diabetic patients, and non-diabetic men and its association with age.Patients and Methods the current study started at the beginning of june 2018 and continued until the end of March 2019 , at the outpatient unit in especial private hospital at Tikrit city - Iraq. Eighty men have been enrolled in present study.Results Eighty men were participate in the present study, distributed as 40 non diabetic subjects as controls and 40 diabetic patients. The mean and standerad deviation of D vit. levels of non-insulin dependant diabetes and normal physically fit men show there is significant reduction of D vit. Measurements of the diabetic men patients suffering from T2DM, (13.58 ± 5.29) as compared with control subjects, (19.95 ± 6.5). there are significant decrease of vit. D measurements of T2DM young patients. In T2DM patients less than 18 years old have significant reduction in vitamin D concentration, (13.41 ± 5.1), as compare with T2DM patients aged 18-40 years, (17.23 ± 7.3). Measuremets of D vit. Durind heat season and compare to cold months.The evaluation of D vit. During hot monthes show significant rise(26.4 ± 7.1) in comparison with winter status(13.65 ± 4.2). Conclusions the present study conclude that, D vit. Levels show highly important increament in hot months as compare with winter season and there are significant reduction in the concentration of vitamin D in young age type 2 diabetic patients
Access to Maternal Healthcare Services during the Pandemic in Specialized Hospitals for Mother and Child Abigael S. Pagatiku; Tentia Vitariani; Ibrahim Shihata; Bambang Ariyanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15586

Abstract

This research aims to see how is access to maternal services in the pandemic era. Maternal patients with COVID-19 without symptoms (co-incidence) can only access a limited number of health facilities and make it more challenging to access healthcare services. Whereas previously, with the integrated referral system, it was easier for patients to access healthcare services. All childbirth during the pandemic takes place in a Healthcare Facility. Pregnant women with suspected, probable, and confirmed COVID-19 would have childbirth at a COVID-19 referral hospital. Based on our study results, as the conclusion, patients with an integrated referral system will be easy to get access to healthcare services. Maternal patients with confirmed COVID-19 without any symptoms have limited access to the health facilities, making access to healthcare services is not easy as before. Easy access to healthcare services is a patient’s right, including a pregnant women’s right with confirmed COVID-19. Therefore, the government needs to increase the number of COVID-19 Referral Hospital. To provide healthcare services, the Specialized Hospital for Mother and Child can handle the normal childbirth of COVID-19 patients. It is necessary to make regulations on the childbirth of COVID-19 patients at the Specialized Hospital for Mother and Child.

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